homoserine lactone (BioDeep_00001868997)
Main id: BioDeep_00000005035
代谢物信息卡片
homoserine lactone
化学式: C4H7NO2 (101.0477)
中文名称: 高丝氨酸内酯
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1COC(=O)C1N
InChI: InChI=1S/C4H7NO2/c5-3-1-2-7-4(3)6/h3H,1-2,5H2
描述信息
A butan-4-olide having an amino substituent at the 2-position.
同义名列表
3 个代谢物同义名
数据库引用编号
10 个数据库交叉引用编号
- ChEBI: CHEBI:17289
- KEGG: C02926
- PubChem: 73509
- CAS: 171736-85-9
- CAS: 1192-20-7
- MetaboLights: MTBLC17289
- PubChem: 5848
- NIKKAJI: J38.532H
- RefMet: Homoserine lactone
- KNApSAcK: 17289
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
2 个相关的物种来源信息
- 7227 - Drosophila melanogaster: 10.1038/S41467-019-11933-Z
- 5691 - Trypanosoma brucei: 10.1371/JOURNAL.PNTD.0001618
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Yongming Duan, Min Han, Maja Grimm, Jessica Ponath, Michael Reichelt, Axel Mithöfer, Adam Schikora. Combination of bacterial N-acyl homoserine lactones primes Arabidopsis defenses via jasmonate metabolism.
Plant physiology.
2023 Jan; ?(?):. doi:
10.1093/plphys/kiad017. [PMID: 36649188] - Abhishek Shrestha, Casandra Hernández-Reyes, Maja Grimm, Johannes Krumwiede, Elke Stein, Sebastian T Schenk, Adam Schikora. AHL-Priming Protein 1 mediates N-3-oxo-tetradecanoyl-homoserine lactone priming in Arabidopsis.
BMC biology.
2022 12; 20(1):268. doi:
10.1186/s12915-022-01464-3. [PMID: 36464707] - Xiang-Yu Cao, Qian Zhao, Ya-Na Sun, Ming-Xiang Yu, Fang Liu, Zhe Zhang, Zhen-Hua Jia, Shui-Shan Song. Cellular messengers involved in the inhibition of the Arabidopsis primary root growth by bacterial quorum-sensing signal N-decanoyl-L-homoserine lactone.
BMC plant biology.
2022 Oct; 22(1):488. doi:
10.1186/s12870-022-03865-6. [PMID: 36229795] - Min Zhu, Yusheng Yang, Meizhen Wang, Xiaoxiao Li, Ruifang Han, Qianqian Chen, Dongsheng Shen, Jiali Shentu. A deep insight into the suppression mechanism of Sedum alfredii root exudates on Pseudomonas aeruginosa based on quorum sensing.
Ecotoxicology and environmental safety.
2021 Jul; 217(?):112240. doi:
10.1016/j.ecoenv.2021.112240. [PMID: 33901783] - Mario López-Martín, Jean-Frédéric Dubern, Morgan R Alexander, Paul Williams. AbaM Regulates Quorum Sensing, Biofilm Formation, and Virulence in Acinetobacter baumannii.
Journal of bacteriology.
2021 03; 203(8):. doi:
10.1128/jb.00635-20. [PMID: 33495249] - Xiaohua Du, Renyan Huang, Zhuo Zhang, Deyong Zhang, Ju'e Cheng, Peijie Tian, Yanqi Wang, Zhongying Zhai, Lijie Chen, Xiaoting Kong, Yong Liu, Pin Su. Rhodopseudomonas palustris Quorum Sensing Molecule pC-HSL Induces Systemic Resistance to TMV Infection via Upregulation of NbSIPK/NbWIPK Expressions in Nicotiana benthamiana.
Phytopathology.
2021 Mar; 111(3):500-508. doi:
10.1094/phyto-05-20-0177-r. [PMID: 32876530] - Wenjie Cai, Fuwen Ou, Christian Staehelin, Weijun Dai. Bradyrhizobium sp. strain ORS278 promotes rice growth and its quorum sensing system is required for optimal root colonization.
Environmental microbiology reports.
2020 12; 12(6):656-666. doi:
10.1111/1758-2229.12885. [PMID: 32929871] - Miguel Medina Munoz, Noah Spencer, Shinichiro Enomoto, Colin Dale, Rita V M Rio. Quorum sensing sets the stage for the establishment and vertical transmission of Sodalis praecaptivus in tsetse flies.
PLoS genetics.
2020 08; 16(8):e1008992. doi:
10.1371/journal.pgen.1008992. [PMID: 32797092] - Xiaofei Qin, Ganesh Kumar Thota, Ratna Singh, Rengarajan Balamurugan, Francisco M Goycoolea. Synthetic homoserine lactone analogues as antagonists of bacterial quorum sensing.
Bioorganic chemistry.
2020 05; 98(?):103698. doi:
10.1016/j.bioorg.2020.103698. [PMID: 32217369] - Xiyi Zhuang, An Zhang, Weihua Chu. Anti-quorum sensing activity of Forsythia suspense extract against Chromobacterium violaceum by targeting CviR receptor.
International microbiology : the official journal of the Spanish Society for Microbiology.
2020 May; 23(2):215-224. doi:
10.1007/s10123-019-00091-3. [PMID: 31342213] - Mi-Young Won, Linda B Oyama, Stephen J Courtney, Christopher J Creevey, Sharon A Huws. Can rumen bacteria communicate to each other?.
Microbiome.
2020 02; 8(1):23. doi:
10.1186/s40168-020-00796-y. [PMID: 32085816] - Fang Liu, Qian Zhao, Zhenhua Jia, Cong Song, Yali Huang, Hong Ma, Shuishan Song. N-3-oxo-octanoyl-homoserine lactone-mediated priming of resistance to Pseudomonas syringae requires the salicylic acid signaling pathway in Arabidopsis thaliana.
BMC plant biology.
2020 Jan; 20(1):38. doi:
10.1186/s12870-019-2228-6. [PMID: 31992205] - Jitendrapuri Gosai, Swetha Anandhan, Anindya Bhattacharjee, G Archana. Elucidation of quorum sensing components and their role in regulation of symbiotically important traits in Ensifer nodulating pigeon pea.
Microbiological research.
2020 Jan; 231(?):126354. doi:
10.1016/j.micres.2019.126354. [PMID: 31678651] - Jun-Wei Zhang, Chen-Guang Xuan, Can-Hua Lu, Song Guo, Jin-Feng Yu, Muhammad Asif, Wen-Jun Jiang, Zhi-Gang Zhou, Zhao-Qing Luo, Li-Qun Zhang. AidB, a Novel Thermostable N-Acylhomoserine Lactonase from the Bacterium Bosea sp.
Applied and environmental microbiology.
2019 12; 85(24):. doi:
10.1128/aem.02065-19. [PMID: 31604771] - Viveka Balasundararajan, Balachandar Dananjeyan. Occurrence of diversified N-acyl homoserine lactone mediated biofilm-forming bacteria in rice rhizoplane.
Journal of basic microbiology.
2019 Oct; 59(10):1031-1039. doi:
10.1002/jobm.201900202. [PMID: 31402466] - Shereen A Murugayah, Monica L Gerth. Engineering quorum quenching enzymes: progress and perspectives.
Biochemical Society transactions.
2019 06; 47(3):793-800. doi:
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Scientific reports.
2019 03; 9(1):4525. doi:
10.1038/s41598-019-40970-3. [PMID: 30872786] - Carla Dias, Marta Ribeiro, Ana Correia-Branco, Raul Domínguez-Perles, Fátima Martel, Maria José Saavedra, Manuel Simões. Virulence, attachment and invasion of Caco-2 cells by multidrug-resistant bacteria isolated from wild animals.
Microbial pathogenesis.
2019 Mar; 128(?):230-235. doi:
10.1016/j.micpath.2019.01.011. [PMID: 30615997] - Frederike Stock, Michail Syrpas, Shiri Graff van Creveld, Simon Backx, Lander Blommaert, Lachlan Dow, Willem Stock, Ewout Ruysbergh, Bernard Lepetit, Benjamin Bailleul, Koen Sabbe, Norbert De Kimpe, Anne Willems, Peter G Kroth, Assaf Vardi, Wim Vyverman, Sven Mangelinckx. N-Acyl Homoserine Lactone Derived Tetramic Acids Impair Photosynthesis in Phaeodactylum tricornutum.
ACS chemical biology.
2019 02; 14(2):198-203. doi:
10.1021/acschembio.8b01101. [PMID: 30694649] - Olena V Moshynets, Lidia M Babenko, Sergiy P Rogalsky, Olga S Iungin, Jessica Foster, Iryna V Kosakivska, Geert Potters, Andrew J Spiers. Priming winter wheat seeds with the bacterial quorum sensing signal N-hexanoyl-L-homoserine lactone (C6-HSL) shows potential to improve plant growth and seed yield.
PloS one.
2019; 14(2):e0209460. doi:
10.1371/journal.pone.0209460. [PMID: 30802259] - Yulia V Zaitseva, Olga A Koksharova, Valentina A Lipasova, Vladimir A Plyuta, Ilya V Demidyuk, Leonid S Chernin, Inessa A Khmel. SprI/SprR Quorum Sensing System of Serratia proteamaculans 94.
BioMed research international.
2019; 2019(?):3865780. doi:
10.1155/2019/3865780. [PMID: 31915691] - Wah Seng See-Too, Peter Convey, David A Pearce, Kok-Gan Chan. Characterization of a novel N-acylhomoserine lactonase, AidP, from Antarctic Planococcus sp.
Microbial cell factories.
2018 Nov; 17(1):179. doi:
10.1186/s12934-018-1024-6. [PMID: 30445965] - Merve Eylul Kiymaci, Nurten Altanlar, Mehmet Gumustas, Sibel A Ozkan, Ahmet Akin. Quorum sensing signals and related virulence inhibition of Pseudomonas aeruginosa by a potential probiotic strain's organic acid.
Microbial pathogenesis.
2018 Aug; 121(?):190-197. doi:
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Food chemistry.
2018 Jul; 255(?):1-7. doi:
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ACS synthetic biology.
2018 06; 7(6):1519-1527. doi:
10.1021/acssynbio.8b00002. [PMID: 29746094] - Marta Potrykus, Nicole Hugouvieux-Cotte-Pattat, Ewa Lojkowska. Interplay of classic Exp and specific Vfm quorum sensing systems on the phenotypic features of Dickeya solani strains exhibiting different virulence levels.
Molecular plant pathology.
2018 May; 19(5):1238-1251. doi:
10.1111/mpp.12614. [PMID: 28921772] - Johannes Arp, Sebastian Götze, Ruchira Mukherji, Derek J Mattern, María García-Altares, Martin Klapper, Debra A Brock, Axel A Brakhage, Joan E Strassmann, David C Queller, Bettina Bardl, Karsten Willing, Gundela Peschel, Pierre Stallforth. Synergistic activity of cosecreted natural products from amoebae-associated bacteria.
Proceedings of the National Academy of Sciences of the United States of America.
2018 04; 115(15):3758-3763. doi:
10.1073/pnas.1721790115. [PMID: 29592954] - Huasong Peng, Yi Ouyang, Muhammad Bilal, Wei Wang, Hongbo Hu, Xuehong Zhang. Identification, synthesis and regulatory function of the N-acylated homoserine lactone signals produced by Pseudomonas chlororaphis HT66.
Microbial cell factories.
2018 Jan; 17(1):9. doi:
10.1186/s12934-017-0854-y. [PMID: 29357848] - Brett L Mellbye, Eva Spieck, Peter J Bottomley, Luis A Sayavedra-Soto. Acyl-Homoserine Lactone Production in Nitrifying Bacteria of the Genera Nitrosospira, Nitrobacter, and Nitrospira Identified via a Survey of Putative Quorum-Sensing Genes.
Applied and environmental microbiology.
2017 Nov; 83(22):. doi:
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Infection and immunity.
2017 09; 85(9):. doi:
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Molecular plant-microbe interactions : MPMI.
2017 07; 30(7):557-565. doi:
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Environmental microbiology reports.
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Journal of biotechnology.
2017 Jan; 241(?):158-162. doi:
10.1016/j.jbiotec.2016.12.002. [PMID: 27923736] - In Seon Kim, Si Young Yang, Seur Kee Park, Young Cheol Kim. Quorum sensing is a key regulator for the antifungal and biocontrol activity of chitinase-producing Chromobacterium sp. C61.
Molecular plant pathology.
2017 01; 18(1):134-140. doi:
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PloS one.
2017; 12(5):e0177647. doi:
10.1371/journal.pone.0177647. [PMID: 28545065] - Simone Rankl, Benet Gunsé, Tina Sieper, Christoph Schmid, Charlotte Poschenrieder, Peter Schröder. Microbial homoserine lactones (AHLs) are effectors of root morphological changes in barley.
Plant science : an international journal of experimental plant biology.
2016 Dec; 253(?):130-140. doi:
10.1016/j.plantsci.2016.09.014. [PMID: 27968982] - Agustín Reyes-Pérez, María Del Carmen Vargas, Magdalena Hernández, Eneas Aguirre-von-Wobeser, Ernesto Pérez-Rueda, Sergio Encarnacion. Transcriptomic analysis of the process of biofilm formation in Rhizobium etli CFN42.
Archives of microbiology.
2016 Nov; 198(9):847-60. doi:
10.1007/s00203-016-1241-5. [PMID: 27226009] - Ran Zhao, Hanmin Zhang, Xiang Zou, Fenglin Yang. Effects of Inhibiting Acylated Homoserine Lactones (AHLs) on Anammox Activity and Stability of Granules'.
Current microbiology.
2016 Jul; 73(1):108-14. doi:
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Journal of natural products.
2016 05; 79(5):1316-21. doi:
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Molecular plant pathology.
2016 May; 17(4):487-500. doi:
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Scientific reports.
2016 Apr; 6(?):24299. doi:
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Molecular systems biology.
2016 Jan; 12(1):849. doi:
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Science signaling.
2016 Jan; 9(409):ra1. doi:
10.1126/scisignal.aaa8271. [PMID: 26732761] - Sivaramakrishnan Subramaniyan, Sasikumar Divyasree, Girija Sadasivan Sandhia. Phytochemicals as Effective Quorum Quenchers Against Bacterial Communication.
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Microbial pathogenesis.
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Microbial cell factories.
2015 Nov; 14(?):191. doi:
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Current microbiology.
2015 Nov; 71(5):585-93. doi:
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Applied and environmental microbiology.
2015 Sep; 81(17):5917-26. doi:
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Analytical and bioanalytical chemistry.
2014 Oct; 406(25):6373-83. doi:
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Life sciences.
2014 Sep; 112(1-2):68-73. doi:
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Cellular microbiology.
2014 Jul; 16(7):1094-104. doi:
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Archives of microbiology.
2014 Mar; 196(3):169-77. doi:
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Chembiochem : a European journal of chemical biology.
2014 Jan; 15(1):87-93. doi:
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Applied and environmental microbiology.
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Journal of bioscience and bioengineering.
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Molecular microbiology.
2013 Nov; 90(3):457-71. doi:
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The Journal of biological chemistry.
2013 Aug; 288(33):23914-27. doi:
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Molecular plant pathology.
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Molecular plant-microbe interactions : MPMI.
2013 Mar; 26(3):356-66. doi:
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Environmental microbiology.
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Microbial ecology.
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Microbiology (Reading, England).
2012 Feb; 158(Pt 2):529-538. doi:
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Plant physiology.
2012 Feb; 158(2):725-36. doi:
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Sensors (Basel, Switzerland).
2012; 12(3):2851-73. doi:
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Sensors (Basel, Switzerland).
2012; 12(3):3327-49. doi:
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Water science and technology : a journal of the International Association on Water Pollution Research.
2012; 66(7):1424-30. doi:
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Environmental microbiology.
2011 Oct; 13(10):2649-66. doi:
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Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi.
2011 Apr; 44(2):144-8. doi:
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Journal of microbiology and biotechnology.
2010 Dec; 20(12):1614-23. doi:
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Phytomedicine : international journal of phytotherapy and phytopharmacology.
2010 Nov; 17(13):1040-6. doi:
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Applied and environmental microbiology.
2010 Sep; 76(18):6119-27. doi:
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Applied and environmental microbiology.
2010 Apr; 76(8):2524-30. doi:
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Journal of agricultural and food chemistry.
2009 Dec; 57(23):11186-93. doi:
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Bioscience, biotechnology, and biochemistry.
2009 Sep; 73(9):2124-7. doi:
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Journal of applied microbiology.
2009 Jan; 106(1):268-77. doi:
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Microbiology (Reading, England).
2009 Jan; 155(Pt 1):124-133. doi:
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Journal of bacteriology.
2008 Jul; 190(13):4398-407. doi:
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Antimicrobial agents and chemotherapy.
2008 Jan; 52(1):198-203. doi:
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Microbiology (Reading, England).
2007 Dec; 153(Pt 12):3923-3938. doi:
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FEMS microbiology ecology.
2007 Aug; 61(2):222-34. doi:
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Philosophical transactions of the Royal Society of London. Series B, Biological sciences.
2007 Jul; 362(1483):1165-83. doi:
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Philosophical transactions of the Royal Society of London. Series B, Biological sciences.
2007 Jul; 362(1483):1235-40. doi:
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Proceedings of the National Academy of Sciences of the United States of America.
2007 Jul; 104(28):11790-5. doi:
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Molecular plant-microbe interactions : MPMI.
2007 Jul; 20(7):843-56. doi:
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Applied and environmental microbiology.
2007 Jun; 73(11):3684-94. doi:
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Applied and environmental microbiology.
2007 Jun; 73(11):3724-7. doi:
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Applied and environmental microbiology.
2007 Jun; 73(11):3669-76. doi:
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Research in microbiology.
2007 Jun; 158(5):463-70. doi:
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Journal of molecular biology.
2007 May; 368(5):1392-402. doi:
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FEMS microbiology letters.
2007 May; 270(2):299-305. doi:
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Microbial ecology.
2007 May; 53(4):524-36. doi:
10.1007/s00248-006-9085-1. [PMID: 17356949] - Selvaraj Poonguzhali, Munusamy Madhaiyan, Tongmin Sa. Quorum-sensing signals produced by plant-growth promoting Burkholderia strains under in vitro and in planta conditions.
Research in microbiology.
2007 Apr; 158(3):287-94. doi:
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FEMS microbiology letters.
2007 Apr; 269(2):213-20. doi:
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Journal of agricultural and food chemistry.
2007 Feb; 55(4):1200-4. doi:
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Analytical and bioanalytical chemistry.
2007 Jan; 387(2):425-35. doi:
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FEMS microbiology letters.
2007 Jan; 266(1):34-41. doi:
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Applied and environmental microbiology.
2007 Jan; 73(2):535-44. doi:
10.1128/aem.01451-06. [PMID: 17085703] - Agnes Fekete, Moritz Frommberger, Michael Rothballer, Xiaojing Li, Matthias Englmann, Jenoe Fekete, Anton Hartmann, Leo Eberl, Philippe Schmitt-Kopplin. Identification of bacterial N-acylhomoserine lactones (AHLs) with a combination of ultra-performance liquid chromatography (UPLC), ultra-high-resolution mass spectrometry, and in-situ biosensors.
Analytical and bioanalytical chemistry.
2007 Jan; 387(2):455-67. doi:
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