Thymidine-5-diphosphate (BioDeep_00001868846)

Main id: BioDeep_00000001708

 

PANOMIX_OTCML-2023


代谢物信息卡片


Thymidine-5-diphosphate

化学式: C10H16N2O11P2 (402.0229)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1=CN(C(=O)NC1=O)C2CC(C(O2)COP(=O)(O)OP(=O)(O)O)O
InChI: InChI=1S/C10H16N2O11P2/c1-5-3-12(10(15)11-9(5)14)8-2-6(13)7(22-8)4-21-25(19,20)23-24(16,17)18/h3,6-8,13H,2,4H2,1H3,(H,19,20)(H,11,14,15)(H2,16,17,18)/t6-,7+,8+/m0/s1

描述信息

A thymidine phosphate having a diphosphate group at the 5-position.
D000890 - Anti-Infective Agents > D000998 - Antiviral Agents
D000970 - Antineoplastic Agents

同义名列表

3 个代谢物同义名

Thymidine-5-diphosphate; dTDP; dTDP



数据库引用编号

13 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

3 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 10 CMPK2, DCK, DGUOK, DHFR, DTYMK, G6PD, GLI3, PKM, TARDBP, TK2
Golgi apparatus, trans-Golgi network membrane 1 ATP2C1
Peripheral membrane protein 2 G6PD, HSD17B6
Endoplasmic reticulum membrane 1 SPCS2
Nucleus 7 DCK, DGUOK, DTYMK, GLI3, LIN9, PKM, TARDBP
cytosol 8 DCK, DGUOK, DHFR, DTYMK, G6PD, GALE, GLI3, PKM
trans-Golgi network 1 ATP2C1
nucleoplasm 7 ATP2B1, CMPK2, DCK, FCF1, GLI3, LIN9, TARDBP
Cell membrane 1 ATP2B1
Early endosome membrane 1 HSD17B6
Multi-pass membrane protein 3 ATP2B1, ATP2C1, SPCS2
Golgi apparatus membrane 1 GBGT1
Synapse 1 ATP2B1
glutamatergic synapse 1 ATP2B1
Golgi apparatus 2 ATP2C1, GBGT1
Golgi membrane 2 ATP2C1, GBGT1
presynaptic membrane 1 ATP2B1
Cytoplasm, cytosol 1 G6PD
plasma membrane 2 ATP2B1, ATP2C1
synaptic vesicle membrane 1 ATP2B1
Membrane 4 ATP2B1, ATP2C1, G6PD, GBGT1
basolateral plasma membrane 1 ATP2B1
extracellular exosome 3 ATP2B1, G6PD, PKM
Lumenal side 1 HSD17B6
endoplasmic reticulum 2 ATP2C1, HSD17B6
mitochondrion 8 CMPK2, DCK, DGUOK, DHFR, DTYMK, PKM, TARDBP, TK2
intracellular membrane-bounded organelle 4 ATP2B1, G6PD, GLI3, HSD17B6
Microsome membrane 1 HSD17B6
extracellular region 1 PKM
cytoplasmic side of plasma membrane 1 G6PD
mitochondrial matrix 3 DGUOK, DTYMK, TK2
centriolar satellite 1 G6PD
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
Extracellular vesicle 1 PKM
nucleolus 2 FCF1, GLI3
Single-pass type II membrane protein 1 GBGT1
vesicle 2 GBGT1, PKM
collagen-containing extracellular matrix 1 PKM
lateral plasma membrane 1 ATP2B1
axoneme 1 GLI3
ciliary tip 1 GLI3
nuclear speck 2 GLI3, TARDBP
ciliary base 1 GLI3
cilium 2 GLI3, PKM
chromatin 1 TARDBP
cell projection 1 ATP2B1
Nucleus, nucleolus 1 FCF1
Basolateral cell membrane 1 ATP2B1
Nucleus, nucleoplasm 1 LIN9
Golgi cisterna membrane 1 ATP2C1
Cytoplasm, Stress granule 1 TARDBP
cytoplasmic stress granule 1 TARDBP
Presynaptic cell membrane 1 ATP2B1
ficolin-1-rich granule lumen 1 PKM
secretory granule lumen 1 PKM
transcription repressor complex 2 GLI3, LIN9
Golgi apparatus, Golgi stack membrane 1 ATP2C1
small-subunit processome 1 FCF1
immunological synapse 1 ATP2B1
perichromatin fibrils 1 TARDBP
intracellular non-membrane-bounded organelle 1 TARDBP
Rough endoplasmic reticulum 1 PKM
cis-Golgi network membrane 1 ATP2C1
GLI-SUFU complex 1 GLI3
photoreceptor ribbon synapse 1 ATP2B1
[Isoform M2]: Cytoplasm 1 PKM
[Isoform M1]: Cytoplasm 1 PKM
signal peptidase complex 1 SPCS2
interchromatin granule 1 TARDBP


文献列表

  • Chitra Bhatia, Stephanie Oerum, James Bray, Kathryn L Kavanagh, Naeem Shafqat, Wyatt Yue, Udo Oppermann. Towards a systematic analysis of human short-chain dehydrogenases/reductases (SDR): Ligand identification and structure-activity relationships. Chemico-biological interactions. 2015 Jun; 234(?):114-25. doi: 10.1016/j.cbi.2014.12.013. [PMID: 25526675]
  • Yun-Gon Kim, Hyung-Yeon Park, Dongwon Yoo, Changmin Sung, Eunjung Song, Jae-Hun Lee, Yun-Hui Choi, Yong-Hyun Kim, Chang-Soo Lee, Kyungmoon Park, Byung-Gee Kim, Yung-Hun Yang. Selective derivatization of nucleotide diphosphate (NDP)-4-keto sugars for electrospray ionization-mass spectrometry (ESI-MS). Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2012 Apr; 893-894(?):177-81. doi: 10.1016/j.jchromb.2012.02.045. [PMID: 22459405]
  • N Tarbouriech, S J Charnock, G J Davies. Three-dimensional structures of the Mn and Mg dTDP complexes of the family GT-2 glycosyltransferase SpsA: a comparison with related NDP-sugar glycosyltransferases. Journal of molecular biology. 2001 Dec; 314(4):655-61. doi: 10.1006/jmbi.2001.5159. [PMID: 11733986]
  • H J Hilderson, M J De Wolf, A R Lagrou, W S Dierick. Subcellular structure of bovine thyroid gland. A study on bovine thyroid membranes by buoyant-density-gradient centrifugation in a B-XIV zonal rotor. The Biochemical journal. 1975 Dec; 152(3):601-7. doi: 10.1042/bj1520601. [PMID: 5997]