methylarsonous acid (BioDeep_00001868763)
Main id: BioDeep_00000006459
代谢物信息卡片
methylarsonous acid
化学式: CH5AsO2 (123.9505)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C[As](O)O
InChI: InChI=1S/CH5AsO2/c1-2(3)4/h3-4H,1H3
描述信息
A one-carbon compound that is arsonous acid in which the hydrogen attached to arsenic is replaced by a methyl group.
同义名列表
2 个代谢物同义名
数据库引用编号
10 个数据库交叉引用编号
- ChEBI: CHEBI:17826
- KEGG: C07295
- PubChem: 161491
- ChEMBL: CHEMBL4097463
- CAS: 25400-23-1
- MetaboLights: MTBLC17826
- PubChem: 9504
- PDB-CCD: 6OL
- NIKKAJI: J622.642F
- KNApSAcK: 17826
分类词条
相关代谢途径
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
- 3039 - Euglena gracilis: 10.3389/FBIOE.2021.662655
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Luis Fernando Negro Silva, Kiran Makhani, Maryse Lemaire, Catherine A Lemarié, Dany Plourde, Alicia M Bolt, Christopher Chiavatti, D Scott Bohle, Stéphanie Lehoux, Mark S Goldberg, Koren K Mann. Sex-Specific Effects of Prenatal and Early Life Inorganic and Methylated Arsenic Exposure on Atherosclerotic Plaque Development and Composition in Adult ApoE-/- Mice.
Environmental health perspectives.
2021 05; 129(5):57008. doi:
10.1289/ehp8171. [PMID: 34014776] - Chao-Yuan Huang, Ying-Chin Lin, Horng-Sheng Shiue, Wei-Jen Chen, Chien-Tien Su, Yeong-Shiau Pu, Pui-Lam Ao, Yu-Mei Hsueh. Comparison of arsenic methylation capacity and polymorphisms of arsenic methylation genes between bladder cancer and upper tract urothelial carcinoma.
Toxicology letters.
2018 Oct; 295(?):64-73. doi:
10.1016/j.toxlet.2018.05.035. [PMID: 29859237] - Mayukh Banerjee, Vanessa Marensi, Gwenaëlle Conseil, X Chris Le, Susan P C Cole, Elaine M Leslie. Polymorphic variants of MRP4/ABCC4 differentially modulate the transport of methylated arsenic metabolites and physiological organic anions.
Biochemical pharmacology.
2016 Nov; 120(?):72-82. doi:
10.1016/j.bcp.2016.09.016. [PMID: 27659809] - Jenna M Currier, María C Ishida, Carmen González-Horta, Blanca Sánchez-Ramírez, Lourdes Ballinas-Casarrubias, Daniela S Gutiérrez-Torres, Roberto Hernández Cerón, Damián Viniegra Morales, Francisco A Baeza Terrazas, Luz M Del Razo, Gonzalo G García-Vargas, R Jesse Saunders, Zuzana Drobná, Rebecca C Fry, Tomáš Matoušek, John B Buse, Michelle A Mendez, Dana Loomis, Miroslav Stýblo. Associations between arsenic species in exfoliated urothelial cells and prevalence of diabetes among residents of Chihuahua, Mexico.
Environmental health perspectives.
2014 Oct; 122(10):1088-94. doi:
10.1289/ehp.1307756. [PMID: 25000461] - Matthew Medeiros, Tam Minh Le, Daniel Troup, Petr Novak, A Jay Gandolfi. Expression Of Selected Pathway-Marker Genes In Human Urothelial Cells Exposed Chronically To A Non-Cytotoxic Concentration Of Monomethylarsonous Acid.
Toxicology reports.
2014; 1(?):421-434. doi:
10.1016/j.toxrep.2014.07.004. [PMID: 25177542] - Puttappa R Dodmane, Lora L Arnold, Satoko Kakiuchi-Kiyota, Fang Qiu, Xiangde Liu, Stephen I Rennard, Samuel M Cohen. Cytotoxicity and gene expression changes induced by inorganic and organic trivalent arsenicals in human cells.
Toxicology.
2013 Oct; 312(?):18-29. doi:
10.1016/j.tox.2013.07.008. [PMID: 23876855] - M Calatayud, V Devesa, D Vélez. Differential toxicity and gene expression in Caco-2 cells exposed to arsenic species.
Toxicology letters.
2013 Mar; 218(1):70-80. doi:
10.1016/j.toxlet.2013.01.013. [PMID: 23353816] - Hua Naranmandura, Shi Xu, Shota Koike, Li Qiang Pan, Bin Chen, Yan Wei Wang, Kanwal Rehman, Bin Wu, Zhe Chen, Noriyuki Suzuki. The endoplasmic reticulum is a target organelle for trivalent dimethylarsinic acid (DMAIII)-induced cytotoxicity.
Toxicology and applied pharmacology.
2012 May; 260(3):241-9. doi:
10.1016/j.taap.2012.02.017. [PMID: 22425709] - Xuefeng Ren, Maria Aleshin, William J Jo, Russel Dills, David A Kalman, Christopher D Vulpe, Martyn T Smith, Luoping Zhang. Involvement of N-6 adenine-specific DNA methyltransferase 1 (N6AMT1) in arsenic biomethylation and its role in arsenic-induced toxicity.
Environmental health perspectives.
2011 Jun; 119(6):771-7. doi:
10.1289/ehp.1002733. [PMID: 21193388] - Craig Steinmaus, Yan Yuan, Dave Kalman, Omar A Rey, Christine F Skibola, Dave Dauphine, Anamika Basu, Kristin E Porter, Alan Hubbard, Michael N Bates, Martyn T Smith, Allan H Smith. Individual differences in arsenic metabolism and lung cancer in a case-control study in Cordoba, Argentina.
Toxicology and applied pharmacology.
2010 Sep; 247(2):138-45. doi:
10.1016/j.taap.2010.06.006. [PMID: 20600216] - Don A Delker, David R Geter, Barbara C Roop, William O Ward, Gene J Ahlborn, James W Allen, Gail M Nelson, Ming Ouyang, William Welsh, Yan Chen, Thomas O'Brien, Kirk T Kitchin. Oncogene expression profiles in K6/ODC mouse skin and papillomas following a chronic exposure to monomethylarsonous acid.
Journal of biochemical and molecular toxicology.
2009 Nov; 23(6):406-18. doi:
10.1002/jbt.20304. [PMID: 20024957] - Kathleen M McCarty, Yen-Ching Chen, Quazi Quamruzzaman, Mahmuder Rahman, Golam Mahiuddin, Yu-Mei Hsueh, Li Su, Thomas Smith, Louise Ryan, David C Christiani. Arsenic methylation, GSTT1, GSTM1, GSTP1 polymorphisms, and skin lesions.
Environmental health perspectives.
2007 Mar; 115(3):341-5. doi:
10.1289/ehp.9152. [PMID: 17431481]
