1,3-Cyclohexanedione (BioDeep_00001868202)

Main id: BioDeep_00000003069

 


代谢物信息卡片


1,3-Cyclohexanedione

化学式: C6H8O2 (112.0524)
中文名称: 1,3-环己二酮
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1CC(=O)CC(=O)C1
InChI: InChI=1S/C6H8O2/c7-5-2-1-3-6(8)4-5/h1-4H2

描述信息

同义名列表

3 个代谢物同义名

1,3-Cyclohexanedione; Cyclohexane-1,3-dione; 1,3-Cyclohexanedione



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 10 CAT, CYP2E1, EGFR, HPD, ITPR3, MSMP, PDGFRB, PMP2, SOD1, TNK1
Peripheral membrane protein 3 CYP2E1, HPD, TNK1
Endosome membrane 1 EGFR
Endoplasmic reticulum membrane 5 CYP2E1, EGFR, HPD, ITPR3, SGPL1
Nucleus 5 EGFR, MET, PDGFRB, PMP2, SOD1
cytosol 6 CAT, FAH, HACL1, HPD, PMP2, SOD1
nuclear body 1 MET
nucleoplasm 4 HACL1, ITPR3, MET, SOD1
Cell membrane 3 EGFR, KIT, PROKR2
Cytoplasmic side 1 SGPL1
ruffle membrane 1 EGFR
Early endosome membrane 1 EGFR
Multi-pass membrane protein 2 ITPR3, PROKR2
Golgi apparatus membrane 1 HPD
cell junction 1 EGFR
cell surface 2 EGFR, MET
glutamatergic synapse 1 EGFR
Golgi apparatus 1 PDGFRB
Golgi membrane 2 EGFR, HPD
mitochondrial inner membrane 1 CYP2E1
neuronal cell body 2 ITPR3, SOD1
postsynapse 1 MET
acrosomal vesicle 1 KIT
endosome 1 EGFR
plasma membrane 9 EGFR, ITPR3, KIT, MET, PDGFRB, PROKR2, RXFP3, RXFP4, TNK1
Membrane 9 CAT, EGFR, ITPR3, KIT, MET, PDGFRB, RXFP3, SGPL1, TNK1
apical plasma membrane 2 EGFR, PDGFRB
basolateral plasma membrane 1 EGFR
brush border 1 ITPR3
extracellular exosome 6 CAT, FAH, HPD, PMP2, SERPINA7, SOD1
endoplasmic reticulum 2 ITPR3, SGPL1
extracellular space 5 EGFR, KIT, MSMP, SERPINA7, SOD1
lysosomal lumen 1 PDGFRB
perinuclear region of cytoplasm 1 EGFR
mitochondrion 2 CAT, SOD1
protein-containing complex 3 CAT, EGFR, SOD1
intracellular membrane-bounded organelle 4 CAT, CYP2E1, HACL1, PDGFRB
Microsome membrane 1 CYP2E1
Single-pass type I membrane protein 2 EGFR, KIT
Secreted 1 MSMP
extracellular region 4 CAT, MET, SERPINA7, SOD1
cytoplasmic side of plasma membrane 1 KIT
Single-pass membrane protein 1 MET
mitochondrial matrix 2 CAT, SOD1
nuclear membrane 1 EGFR
external side of plasma membrane 1 KIT
cytoplasmic vesicle 2 PDGFRB, SOD1
nucleolus 1 ITPR3
axon cytoplasm 1 SOD1
apical part of cell 1 ITPR3
cell-cell junction 1 KIT
Mitochondrion inner membrane 1 CYP2E1
Membrane raft 1 EGFR
focal adhesion 3 CAT, EGFR, PDGFRB
Peroxisome 3 CAT, HACL1, SOD1
intracellular vesicle 1 EGFR
sarcoplasmic reticulum 1 ITPR3
Peroxisome matrix 1 CAT
peroxisomal matrix 2 CAT, HACL1
peroxisomal membrane 1 CAT
mitochondrial intermembrane space 1 SOD1
nuclear outer membrane 1 ITPR3
dendrite cytoplasm 1 SOD1
receptor complex 5 EGFR, ITPR3, KIT, MET, PDGFRB
fibrillar center 1 KIT
myelin sheath 1 PMP2
basal plasma membrane 2 EGFR, MET
[Isoform 3]: Cytoplasm 1 KIT
synaptic membrane 1 EGFR
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 1 CAT
secretory granule membrane 1 ITPR3
Single-pass type III membrane protein 1 SGPL1
clathrin-coated endocytic vesicle membrane 1 EGFR
platelet dense tubular network membrane 1 ITPR3
Cytoplasmic vesicle, secretory vesicle membrane 1 ITPR3
hemoglobin complex 1 HBA1
multivesicular body, internal vesicle lumen 1 EGFR
Shc-EGFR complex 1 EGFR
transport vesicle membrane 1 ITPR3
catalase complex 1 CAT
cytoplasmic side of endoplasmic reticulum membrane 1 ITPR3


文献列表

  • Wei Zhang, Radhia Benmohamed, Anthony C Arvanites, Richard I Morimoto, Robert J Ferrante, Donald R Kirsch, Richard B Silverman. Cyclohexane 1,3-diones and their inhibition of mutant SOD1-dependent protein aggregation and toxicity in PC12 cells. Bioorganic & medicinal chemistry. 2012 Jan; 20(2):1029-45. doi: 10.1016/j.bmc.2011.11.039. [PMID: 22189273]
  • Alinanuswe S Mwakaboko, Binne Zwanenburg. Single step synthesis of strigolactone analogues from cyclic keto enols, germination stimulants for seeds of parasitic weeds. Bioorganic & medicinal chemistry. 2011 Aug; 19(16):5006-11. doi: 10.1016/j.bmc.2011.06.057. [PMID: 21757362]
  • Weiwei Zi, Shouyun Yu, Dawei Ma. Synthetic studies toward galbulimima alkaloid (-)-GB 13 and (+)-GB 16 and (-)-himgaline. Chemistry, an Asian journal. 2011 Feb; 6(2):573-9. doi: 10.1002/asia.201000556. [PMID: 21254431]
  • Flaviana T Vieira, Geraldo M de Lima, José R da S Maia, Nivaldo L Speziali, José D Ardisson, Leonardo Rodrigues, Ary Correa, Oscar B Romero. Synthesis, characterization and biocidal activity of new organotin complexes of 2-(3-oxocyclohex-1-enyl)benzoic acid. European journal of medicinal chemistry. 2010 Mar; 45(3):883-9. doi: 10.1016/j.ejmech.2009.11.026. [PMID: 19959261]
  • Tae-Joon Kim, Jin-Seog Kim, Kyoung Sik Hong, In-Taek Hwang, Kyoung Mahn Kim, Hyeong-Rae Kim, Kwang Yun Cho. EK-2612, a new cyclohexane-1,3-dione possessing selectivity between rice (Oryza sativa) and barnyardgrass (Echinochloa crus-galli). Pest management science. 2004 Sep; 60(9):909-13. doi: 10.1002/ps.868. [PMID: 15382506]
  • Ralph W Howard, James E Baker. Stage-specific surface chemicals of Plodia interpunctella: 2-acyl-1,3-cyclohexanediones from larval mandibular glands serve as cuticular lipids. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 2004 Jun; 138(2):193-206. doi: 10.1016/j.cbpc.2004.03.008. [PMID: 15193275]
  • Tahar Mechichi, Erko Stackebrandt, Georg Fuchs. Alicycliphilus denitrificans gen. nov., sp. nov., a cyclohexanol-degrading, nitrate-reducing beta-proteobacterium. International journal of systematic and evolutionary microbiology. 2003 Jan; 53(Pt 1):147-152. doi: 10.1099/ijs.0.02276-0. [PMID: 12661531]
  • S Ishimitsu, A Kaihara, K Yoshii, Y Tsumura, Y Nakamura, Y Tonogai. Determination of clethodim and its oxidation metabolites in crops by liquid chromatography with confirmation by LC/MS. Journal of AOAC International. 2001 Jul; 84(4):1172-8. doi: NULL. [PMID: 11501920]
  • S R Webb, J C Hall. Polyclonal-based ELISA for the identification of cyclohexanedione analogs that inhibit maize acetyl coenzyme-A carboxylase. Journal of AOAC International. 2001 Jan; 84(1):143-9. doi: 10.1093/jaoac/84.1.143. [PMID: 11234801]
  • A E Holley, M K Walker, K H Cheeseman, T F Slater. Measurement of n-alkanals and hydroxyalkenals in biological samples. Free radical biology & medicine. 1993 Sep; 15(3):281-9. doi: 10.1016/0891-5849(93)90075-6. [PMID: 8406128]
  • J K Beckman, S A Morley, H L Greene. Analysis of aldehydic lipid peroxidation products by TLC/densitometry. Lipids. 1991 Feb; 26(2):155-61. doi: 10.1007/bf02544011. [PMID: 1904971]
  • M K Samson, R L Stephens, S Rivkin, M Opipari, T Maloney, C W Groppe, R Fisher. Vinblastine, bleomycin, and cis-dichlorodiammineplatinum(II) in disseminated testicular cancer: preliminary report of a Southwest Oncology Group Study. Cancer treatment reports. 1979 Sep; 63(9-10):1663-7. doi: . [PMID: 91435]