semustine (BioDeep_00001868020)
Main id: BioDeep_00000006559
Volatile Flavor Compounds
代谢物信息卡片
化学式: C10H18ClN3O2 (247.1087478)
中文名称: 司莫司汀, 塞莫司汀
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1CCC(CC1)NC(=O)N(CCCl)N=O
InChI: InChI=1S/C10H18ClN3O2/c1-8-2-4-9(5-3-8)12-10(15)14(13-16)7-6-11/h8-9H,2-7H2,1H3,(H,12,15)
描述信息
L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01A - Alkylating agents > L01AD - Nitrosoureas
C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C2842 - DNA Binding Agent
D009676 - Noxae > D000477 - Alkylating Agents
D000970 - Antineoplastic Agents
同义名列表
数据库引用编号
14 个数据库交叉引用编号
- ChEBI: CHEBI:6863
- KEGG: C07640
- KEGGdrug: D05822
- PubChem: 5198
- ChEMBL: CHEMBL1967746
- ChEMBL: CHEMBL2051944
- ChEMBL: CHEMBL12948
- MeSH: Semustine
- CAS: 13909-09-6
- CAS: 33073-59-5
- CAS: 33185-87-4
- PubChem: 9842
- NIKKAJI: J8.456E
- KNApSAcK: 6863
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Guangrong Lu, Liping Chen, Shengjie Wu, Yuao Feng, Tiesu Lin. Comprehensive Analysis of Tumor-Infiltrating Immune Cells and Relevant Therapeutic Strategy in Esophageal Cancer.
Disease markers.
2020; 2020(?):8974793. doi:
10.1155/2020/8974793
. [PMID: 32454908] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964
. [PMID: 31515284] - Zheng-Ping Yu, Jia-Hua Ding, Ai-Ning Sun, Bao-An Chen, Zheng Ge, De-Pei Wu. A New Conditioning Regimen Can Significantly Promote Post-Transplant Immune Reconstitution and Improve the Outcome of Umbilical Cord Blood Transplantation for Patients.
Stem cells and development.
2019 10; 28(20):1376-1383. doi:
10.1089/scd.2019.0139
. [PMID: 31464164] - Eu Jin Lim, Ruth Chin, Ueli Nachbur, John Silke, Zhiyuan Jia, Peter W Angus, Joseph Torresi. Effect of Immunosuppressive Agents on Hepatocyte Apoptosis Post-Liver Transplantation.
PloS one.
2015; 10(9):e0138522. doi:
10.1371/journal.pone.0138522
. [PMID: 26390404] - Yasuto Kido, Pär Matsson, Kathleen M Giacomini. Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2.
Journal of medicinal chemistry.
2011 Jul; 54(13):4548-58. doi:
10.1021/jm2001629
. [PMID: 21599003] - Evrim Sahin, Anna M Petrunkina, Dagmar Waberski, Robin A P Harrison, Edda Töpfer-Petersen. Control of bull sperm cell volume during epididymal maturation.
Reproduction, fertility, and development.
2009; 21(3):469-78. doi:
10.1071/rd08162
. [PMID: 19261224] - Leonard C Hymes, Laurence Greenbaum, Sandra G Amaral, Barry L Warshaw. Surveillance renal transplant biopsies and subclinical rejection at three months post-transplant in pediatric recipients.
Pediatric transplantation.
2007 Aug; 11(5):536-9. doi:
10.1111/j.1399-3046.2007.00705.x
. [PMID: 17631023] - P E Kintzel. Anticancer drug-induced kidney disorders.
Drug safety.
2001 Jan; 24(1):19-38. doi:
10.2165/00002018-200124010-00003
. [PMID: 11219485] - K Kuze, P Graves, A Leahy, P Wilson, H Stuhlmann, G You. Heterologous expression and functional characterization of a mouse renal organic anion transporter in mammalian cells.
The Journal of biological chemistry.
1999 Jan; 274(3):1519-24. doi:
10.1074/jbc.274.3.1519
. [PMID: 9880528] - F Cachat, J P Guignard. [The kidney in children under chemotherapy].
Revue medicale de la Suisse romande.
1996 Dec; 116(12):985-93. doi:
NULL
. [PMID: 9026889] - M E Dolan, L Stine, R B Mitchell, R C Moschel, A E Pegg. Modulation of mammalian O6-alkylguanine-DNA alkyltransferase in vivo by O6-benzylguanine and its effect on the sensitivity of a human glioma tumor to 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea.
Cancer communications.
1990; 2(11):371-7. doi:
10.3727/095535490820873985
. [PMID: 2242301] - R C Vyas, S G Adhvaryu, V C Shah. Genotoxic effects of MeCCNU on human peripheral blood lymphocytes.
Toxicology letters.
1988 Nov; 44(1-2):153-9. doi:
10.1016/0378-4274(88)90141-5
. [PMID: 3188073] - Y Yegana, A Zimber, K Perk. The effect of high doses of methyl-CCNU on male and female fertility in SJL/J mice.
Anticancer research.
1988 May; 8(3):397-401. doi:
NULL
. [PMID: 3389744] - A Zimber, K Perk, I Livnat. Priming with low doses of methyl-CCNU reduce the toxicity of high doses of methyl-CCNU and melphalan, and increase the lifespan of mice implanted with Lewis lung carcinoma.
British journal of cancer.
1988 Mar; 57(3):266-70. doi:
10.1038/bjc.1988.57
. [PMID: 3355764] - M J O'Connell, A J Schutt, C G Moertel, J Rubin, R G Hahn, M Scott. A randomized clinical trial of combination chemotherapy in advanced colorectal cancer.
American journal of clinical oncology.
1987 Aug; 10(4):320-4. doi:
10.1097/00000421-198708000-00013
. [PMID: 3303905] - P R Thomas, D M Stablein, S M Steinberg, J S Barkin, R J Nauta. The effects of liver directed radiotherapy and chemotherapy on liver function tests and hematological parameters in patients with surgically resected colon cancer: findings from the Gastrointestinal Tumor Study Group.
The American journal of gastroenterology.
1987 Aug; 82(8):738-43. doi:
NULL
. [PMID: 3300276] - Y Kubo, M Abe, Y Majima, K Hirai. [Current status of diagnosis and treatment of metastatic liver cancer].
Gan to kagaku ryoho. Cancer & chemotherapy.
1987 Mar; 14(3 Pt 1):590-9. doi:
NULL
. [PMID: 2435244] - D K Todorov, K K Silyanovska, K M Maneva, M V Ilarionova, G T Gantchev, C M Getov. Chemo- and immunotherapy of an adenovirus-induced transplantable sarcoma in hamsters.
Neoplasma.
1987; 34(3):287-94. doi:
. [PMID: 3039387]
- F Ries, J Klastersky. Nephrotoxicity induced by cancer chemotherapy with special emphasis on cisplatin toxicity.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
1986 Nov; 8(5):368-79. doi:
10.1016/s0272-6386(86)80112-3
. [PMID: 3538860] - R A Kramer, M G McMenamin, M R Boyd. In vivo studies on the relationship between hepatic metabolism and the renal toxicity of 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea (MeCCNU).
Toxicology and applied pharmacology.
1986 Sep; 85(2):221-30. doi:
10.1016/0041-008x(86)90116-x
. [PMID: 3764909] - R A Kramer, M R Boyd, J H Dees. Comparative nephrotoxicity of 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea (MeCCNU) and chlorozotocin: functional-structural correlations in the Fischer 344 rat.
Toxicology and applied pharmacology.
1986 Mar; 82(3):540-50. doi:
10.1016/0041-008x(86)90289-9
. [PMID: 2937179] - T Takahashi. Emulsion and activated carbon in cancer chemotherapy.
Critical reviews in therapeutic drug carrier systems.
1986; 2(3):245-74. doi:
"
. [PMID: 2424623] - P F Engstrom, J M MacIntyre, A J Schutt, H O Douglass. Chemotherapy of large bowel carcinoma--fluorouracil (FU) + hydroxyurea (HU) vs. methyl-CCNU, oncovin, fluorouracil, and streptozotocin (MOF-Strep). An Eastern Cooperative Oncology Group study.
American journal of clinical oncology.
1985 Oct; 8(5):358-61. doi:
10.1097/00000421-198510000-00004
. [PMID: 2932908] - R A Kramer, H M Schuller, A C Smith, M R Boyd. Effects of buthionine sulfoximine on the nephrotoxicity of 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea (MeCCNU).
The Journal of pharmacology and experimental therapeutics.
1985 Aug; 234(2):498-506. doi:
NULL
. [PMID: 4020683] - R A Kramer, M G McMenamin, M R Boyd. Differential distribution and covalent binding of two labeled forms of methyl-CCNU in the Fischer 344 rat.
Cancer chemotherapy and pharmacology.
1985; 14(2):150-5. doi:
10.1007/bf00434355
. [PMID: 3971479] - S Frytak, C G Moertel, J Rubin. Metabolic studies of delta-9-tetrahydrocannabinol in cancer patients.
Cancer treatment reports.
1984 Dec; 68(12):1427-31. doi:
NULL
. [PMID: 6095996] - F Y Lee, P Workman. Nitroimidazoles as modifiers of nitrosourea pharmacokinetics.
International journal of radiation oncology, biology, physics.
1984 Sep; 10(9):1627-30. doi:
10.1016/0360-3016(84)90516-9
. [PMID: 6237080] - S Pavlovsky, J Saslavsky, M Tezanos Pinto, L Palmer, M Curuchet, J M Lein, G Garay, M Dragosky, E Quiroga-Micheo, A B Huberman. A randomized trial of melphalan and prednisone versus melphalan, prednisone, cyclophosphamide, MeCCNU, and vincristine in untreated multiple myeloma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
1984 Jul; 2(7):836-40. doi:
10.1200/jco.1984.2.7.836
. [PMID: 6376722] - I D Goldberg, M B Garnick, W D Bloomer. Urinary tract toxic effects of cancer therapy.
The Journal of urology.
1984 Jul; 132(1):1-6. doi:
10.1016/s0022-5347(17)49438-9
. [PMID: 6233430] - K R Hine, P W Dykes. Prospective randomised trial of early cytotoxic therapy for recurrent colorectal carcinoma detected by serum CEA.
Gut.
1984 Jun; 25(6):682-8. doi:
10.1136/gut.25.6.682
. [PMID: 6376291] - D W Potter, W Levin, D E Ryan, P E Thomas, D J Reed. Stereoselective monooxygenation of carcinostatic 1-(2-chloroethyl)-3-(cyclohexyl)-1-nitrosourea and 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea by purified cytochrome P-450 isozymes.
Biochemical pharmacology.
1984 Feb; 33(4):609-13. doi:
10.1016/0006-2952(84)90316-2
. [PMID: 6704177] - T T Antonovych. Drug-induced nephropathies.
Pathology annual.
1984; 19 Pt 2(?):165-96. doi:
NULL
. [PMID: 6390307] - R B Weiss, J G Posada, R A Kramer, M R Boyd. Nephrotoxicity of semustine.
Cancer treatment reports.
1983 Dec; 67(12):1105-12. doi:
. [PMID: 6360348]
- R A Kramer, M R Boyd. Nephrotoxicity of 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea (MeCCNU) in the Fischer 344 rat.
The Journal of pharmacology and experimental therapeutics.
1983 Nov; 227(2):409-14. doi:
NULL
. [PMID: 6631721] - H Windschitl, M Scott, A Schutt, G McCormack, L Everson, S Cullinan, J Gerstner, J Krook, J Laurie, R Shreck. Randomized phase II studies in advanced colorectal carcinoma: a North Central Cancer Treatment Group study.
Cancer treatment reports.
1983 Nov; 67(11):1001-8. doi:
NULL
. [PMID: 6640551] - F Dumler. Drug-induced glomerulopathy: a selective review.
Henry Ford Hospital medical journal.
1983; 31(2):110-4. doi:
NULL
. [PMID: 6414992] - S D Harrison, J L Cox, R C Giles. Effects of prochlorperazine on experimental nephrotoxicity.
Cancer chemotherapy and pharmacology.
1982 Dec; 10(1):62-7. doi:
10.1007/bf00257241
. [PMID: 6218930] - A E Brandt. Correspondence re: J. H. Pincus, A. K. Jameson, and A. E. Brandt. Immunotherapy of L1210 leukemia using neuraminidase-modified plasma membranes combined with chemotherapy. Cancer Res., 41: 3082-3086, 1981.
Cancer research.
1982 Oct; 42(10):4263-4. doi:
NULL
. [PMID: 7105020] - S K Joishy, J M Bennett, M Balasegaram, J M MacIntyre, G Falkson, C Moertel, P P Carbone. Clinical and chemotherapeutic study of hepatocellular carcinoma in Malaysia: a comparison with African and American patients.
Cancer.
1982 Sep; 50(6):1065-9. doi:
10.1002/1097-0142(19820915)50:6<1065::aid-cncr2820500608>3.0.co;2-b
. [PMID: 6286085] - A Wakui. [Cancer chemotherapy with special reference to pharmacokinetics of nitrosoureas].
Gan to kagaku ryoho. Cancer & chemotherapy.
1982 Aug; 9(8):1327-38. doi:
"
. [PMID: 6223595] - R G Smith, L K Cheung. Determination of two nitrosourea antitumor agents by chemical ionization gas chromatography--mass spectrometry.
Journal of chromatography.
1982 May; 229(2):464-9. doi:
10.1016/s0378-4347(00)84292-9
. [PMID: 7096484] - B Caddy, O R Idowu. Gas-chromatographic determination of 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea (methyl-CCNU). Part III. Denitrosation to the parent urea.
The Analyst.
1982 May; 107(1274):556-65. doi:
10.1039/an9820700556
. [PMID: 7103097] - B Caddy, O R Idowu. Gas-chromatographic determination of 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea (methyl-CCNU) Part II. Reduction to semicarbazide with sodium tetrahydroborate (III).
The Analyst.
1982 May; 107(1274):550-5. doi:
10.1039/an9820700550
. [PMID: 7103096] - B Caddy, O R Idowu, J F Stuart. A high pressure liquid chromatographic procedure for monitoring 1-(2-chloroethyl)-3-(4-trans-methylcyclohexyl)-1-nitrosourea levels in body fluids.
Therapeutic drug monitoring.
1982; 4(4):389-95. doi:
10.1097/00007691-198212000-00010
. [PMID: 7157463] - K C Micetich, M Jensen-Akula, J C Mandard, R I Fisher. Nephrotoxicity of semustine (methyl-CCNU) in patients with malignant melanoma receiving adjuvant chemotherapy.
The American journal of medicine.
1981 Dec; 71(6):967-72. doi:
10.1016/0002-9343(81)90315-6
. [PMID: 7032289] - R G Schacht, H D Feiner, G R Gallo, A Lieberman, D S Baldwin. Nephrotoxicity of nitrosoureas.
Cancer.
1981 Sep; 48(6):1328-34. doi:
10.1002/1097-0142(19810915)48:6<1328::aid-cncr2820480613>3.0.co;2-n
. [PMID: 7272960] - R T Chlebowski, K K Chan, M J Tong, J M Weiner, V M Ryden, J R Bateman. Adriamycin and methyl-CCNU combination therapy in hepatocellular carcinoma: clinical and pharmacokinetic aspects.
Cancer.
1981 Sep; 48(5):1088-95. doi:
10.1002/1097-0142(19810901)48:5<1088::aid-cncr2820480507>3.0.co;2-w
. [PMID: 6268277] - J H Pincus, A K Jameson, A E Brandt. Immunotherapy of L1210 leukemia using neuraminidase-modified plasma membranes combined with chemotherapy.
Cancer research.
1981 Aug; 41(8):3082-6. doi:
. [PMID: 7248965]
- M Inaba, N Yoshida, S Tsukagoshi. Preferential action of liposome-entrapped 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea on lung metastasis of Lewis lung carcinoma as compared with the free drug.
Gan.
1981 Jun; 72(3):341-5. doi:
. [PMID: 7319193]
- P D Williams, P Kantor, G P Murphy. Evaluation of vincristine, CCNU and methyl-CCNU at high level doses in an experimental murine renal adenocarcinoma model.
Research communications in chemical pathology and pharmacology.
1981 Mar; 31(3):529-36. doi:
NULL
. [PMID: 7255884] - S J Kohlhepp, H E May, D J Reed. Urinary metabolites of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea and 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea.
Drug metabolism and disposition: the biological fate of chemicals.
1981 Mar; 9(2):135-41. doi:
. [PMID: 6113112]
- K Komiyama, K Edanami, T Kuroda, I Umezawa. Antitumor effect of 3-[3-(2-chloroethyl)-3-nitrosoureido]-3-deoxy-D-glucopyranose on murine tumors.
Gan.
1981 Feb; 72(1):53-9. doi:
NULL
. [PMID: 6456168] - R J Weinkam, A Finn, V A Levin, J P Kane. Lipophilic drugs and lipoproteins: partitioning effects on chloroethylnitrosourea reaction rates in serum.
The Journal of pharmacology and experimental therapeutics.
1980 Aug; 214(2):318-23. doi:
NULL
. [PMID: 7391979] - M T Ercan, I S Or, C F Bekdik, T Sarizi, A Yazicioglu. 99mTc-methyl-CCNU for the static imaging of kidneys.
European journal of nuclear medicine.
1980 Apr; 5(2):109-14. doi:
10.1007/bf00252468
. [PMID: 7379812] - P Kari, W R McConnell, J M Finkel, D L Hill. Distribution of Bratton-Marshall-positive material in mice following intravenous injections of nitrosoureas.
Cancer chemotherapy and pharmacology.
1980; 4(4):243-8. doi:
10.1007/bf00255268
. [PMID: 7438326] - W C Nichols, C G Moertel. Nephrotoxicity of methyl CCNU.
The New England journal of medicine.
1979 Nov; 301(21):1181. doi:
10.1056/nejm197911223012113
. [PMID: 492286] - W E Harmon, H J Cohen, E E Schneeberger, W E Grupe. Chronic renal failure in children treated with methyl CCNU.
The New England journal of medicine.
1979 May; 300(21):1200-3. doi:
10.1056/nejm197905243002106
. [PMID: 431647] - A W Schrecker, R M Schultz, M A Chirigos. Effect of macrophage activation by immunoadjuvants on serum levels of lysosomal hydrolases in mice.
Journal of immunopharmacology.
1979; 1(2):219-31. doi:
10.3109/08923977909026373
. [PMID: 553109] - A Zimber, K Perk. The effect of early treatment with methyl-CCNU on the lymphoid organs and the humoral immune response in chickens.
Poultry science.
1979 Jan; 58(1):162-72. doi:
10.3382/ps.0580162
. [PMID: 471882] - B L Hillcoat, P B McCulloch, A T Figueredo, M H Ehsan, J M Rosenfeld. Clinical response and plasma levels of 5-fluorouracil in patients with colonic cancer treated by drug infusion.
British journal of cancer.
1978 Dec; 38(6):719-24. doi:
10.1038/bjc.1978.278
. [PMID: 743489] - Z Zimber, K Perk. Male sterility in the domestic fowl (Gallus domesticus) after 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitroso-trans-urea (NSC-95441) treatment of chicks.
Journal of the National Cancer Institute.
1978 Sep; 61(3):793-7. doi:
NULL
. [PMID: 278856] - R G Hahn, N R Temkin, E D Savlov, C Perlia, G L Wampler, J Horton, J Marsh, P P Carbone. Phase II study of vinblastine, methyl-CCNU, and medroxyprogesterone in advanced renal cell cancer.
Cancer treatment reports.
1978 Jul; 62(7):1093-5. doi:
. [PMID: 356971]
- N M Blackett, J C Marsh, M Y Gordon, S F Okell, M Aguado. Simultaneous assay by six methods of the effect on haemopoietic precursor cells of adriamycin, methyl CCNU, 60Co gamma-rays, vinblastine, and cytosine arabinoside.
Experimental hematology.
1978 Jan; 6(1):2-8. doi:
. [PMID: 342260]
- J J Lokich, A T Skarin, R J Mayer, E Frei. Lack of effectiveness of combined 5- fluorouracil and methyl-CCNU therapy in advanced colorectal cancer.
Cancer.
1977 Dec; 40(6):2792-6. doi:
10.1002/1097-0142(197712)40:6<2792::aid-cncr2820400606>3.0.co;2-r
. [PMID: 589555] - L E Posey, L R Morgan. Methyl-CCNU versus methyl-CCNU and 5-fluorouracil in carcinoma of the large bowel.
Cancer treatment reports.
1977 Nov; 61(8):1453-8. doi:
. [PMID: 922750]
- E P Denine, S D Harrison, J C Peckham. Qualitative and quantitative toxicity of sublethal doses of methyl-CCNU in BDF1 mice.
Cancer treatment reports.
1977 May; 61(3):409-17. doi:
NULL
. [PMID: 872140] - W J Hrushesky, G P Murphy. Current status of the therapy of advanced renal carcinoma.
Journal of surgical oncology.
1977; 9(3):277-88. doi:
10.1002/jso.2930090310
. [PMID: 327158] - M Slavik. Clinical studies with nitrosoureas in various solid tumors.
Cancer treatment reports.
1976 Jun; 60(6):795-800. doi:
NULL
. [PMID: 986243] - D L Ahmann, H F Bisel, J H Edmonson, R G Hahn, R T Eagan, M J O'Connell, S Frytak. Clinical comparison of adriamycin and a combination of methyl-CCNU and imidazole carboxamide in disseminated malignant melanoma.
Clinical pharmacology and therapeutics.
1976 Jun; 19(6):821-4. doi:
10.1002/cpt1976196821
. [PMID: 773589] - W Dorn, M P Gladden, E A Rankin. Regression of a renal-cell metastatic osseous lesion following treatment.
The Journal of bone and joint surgery. American volume.
1975 Sep; 57(6):869-70. doi:
10.2106/00004623-197557060-00033
. [PMID: 1158935] - J A Greager, G Culberson, B Manning, T K Das Cupta. Chemotherapy, BCG, and serum from tumor-bearing mice: comparative effects on growth and spread of mouse Lewis lung cancer.
Archives of surgery (Chicago, Ill. : 1960).
1975 Aug; 110(8):901-2. doi:
10.1001/archsurg.1975.01360140045009
. [PMID: 1156156]