chlorambucil (BioDeep_00001867781)
Main id: BioDeep_00000006377
代谢物信息卡片
chlorambucil
化学式: C14H19Cl2NO2 (303.0792774)
中文名称: 氯氨布西
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(Cc1ccc(cc1)N(CCCl)CCCl)CC(=O)O
InChI: InChI=1S/C14H19Cl2NO2/c15-8-10-17(11-9-16)13-6-4-12(5-7-13)2-1-3-14(18)19/h4-7H,1-3,8-11H2,(H,18,19)
描述信息
L - Antineoplastic and immunomodulating agents > L01 - Antineoplastic agents > L01A - Alkylating agents > L01AA - Nitrogen mustard analogues
D000970 - Antineoplastic Agents > D018906 - Antineoplastic Agents, Alkylating > D009588 - Nitrogen Mustard Compounds
C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C2842 - DNA Binding Agent
D009676 - Noxae > D000477 - Alkylating Agents
同义名列表
1 个代谢物同义名
数据库引用编号
12 个数据库交叉引用编号
- ChEBI: CHEBI:28830
- KEGG: C06900
- KEGGdrug: D00266
- PubChem: 2708
- DrugBank: DB00291
- ChEMBL: CHEMBL515
- MeSH: Chlorambucil
- CAS: 305-03-3
- PubChem: 9117
- PDB-CCD: CBL
- NIKKAJI: J1.521K
- RefMet: Chlorambucil
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Swagata Patra, Joykrishna Dey, Somnath Kar, Avik Chakraborty. Delivery of Chlorambucil to the Brain Using Surface Modified Solid Lipid Nanoparticles.
ACS applied bio materials.
2024 May; 7(5):3403-3413. doi:
10.1021/acsabm.4c00326. [PMID: 38700026] - Yiping Dong, Congcong Luo, Ning Zhang, Ruonan You, Qiang Yuan, Wuyin Li, Ying Zhang. [Correlation between combined deflection angle classification adduction typing and complications after internal fixation of adduction femoral neck fracture].
Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery.
2024 Apr; 38(4):405-411. doi:
10.7507/1002-1892.202401063. [PMID: 38632058] - Francesco Siano, Gianluca Picariello, Domenico Castaldo, Domenico Cautela, Tonino Caruso, Ermanno Vasca. Monitoring antioxidants by coulometry: Quantitative assessment of the strikingly high antioxidant capacity of bergamot (Citrus bergamia R.) by-products.
Talanta.
2023 Jan; 251(?):123765. doi:
10.1016/j.talanta.2022.123765. [PMID: 35931010] - Lihong Sang, Ji Li, Faxing Zhang, Jiajia Jia, Jian Zhang, Pingtian Ding, Ting Sun, Dongkai Wang. Glycyrrhetinic acid modified chlorambucil prodrug for hepatocellular carcinoma treatment based on DNA replication and tumor microenvironment.
Colloids and surfaces. B, Biointerfaces.
2022 Dec; 220(?):112864. doi:
10.1016/j.colsurfb.2022.112864. [PMID: 36272286] - Minjie Zhang, Xin Jin, Meng Gao, Yunjiao Zhang, Ben Zhong Tang. A Self-Reporting Fluorescent Salicylaldehyde-Chlorambucil Conjugate as a Type-II ICD Inducer for Cancer Vaccines.
Advanced materials (Deerfield Beach, Fla.).
2022 Sep; 34(36):e2205701. doi:
10.1002/adma.202205701. [PMID: 35863361] - Shintaro Funasaki, Sally Mehanna, Wenjuan Ma, Hidekazu Nishizawa, Yasuhiko Kamikubo, Hiroshi Sugiyama, Shuji Ikeda, Takanobu Motoshima, Hisashi Hasumi, W Marston Linehan, Laura S Schmidt, Chris Ricketts, Toshio Suda, Yuichi Oike, Tomomi Kamba, Masaya Baba. Targeting chemoresistance in Xp11.2 translocation renal cell carcinoma using a novel polyamide-chlorambucil conjugate.
Cancer science.
2022 Jul; 113(7):2352-2367. doi:
10.1111/cas.15364. [PMID: 35396773] - Koji Sugita, Ayaka Shima, Kaho Takahashi, Yasuyoshi Matsuda, Masaki Miyajima, Marin Hirokawa, Hirotaka Kondo, Junpei Kimura, Genki Ishihara, Keitaro Ohmori. Successful outcome after a single endoscopic fecal microbiota transplantation in a Shiba dog with non-responsive enteropathy during the treatment with chlorambucil.
The Journal of veterinary medical science.
2021 Jul; 83(6):984-989. doi:
10.1292/jvms.21-0063. [PMID: 33896875] - Katarzyna Lipska, Anna Gumieniczek, Rafał Pietraś, Agata A Filip. HPLC-UV and GC-MS Methods for Determination of Chlorambucil and Valproic Acid in Plasma for Further Exploring a New Combined Therapy of Chronic Lymphocytic Leukemia.
Molecules (Basel, Switzerland).
2021 May; 26(10):. doi:
10.3390/molecules26102903. [PMID: 34068372] - Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Snezana Uncanin, Jasminka Dzemidzic, Nafija Serdarevic, Alma Muslimovic, Denis Haskovic. Idiopathic Membranous Nephropathy and Treatment Related Complications.
Medical archives (Sarajevo, Bosnia and Herzegovina).
2020 Jun; 74(3):228-232. doi:
10.5455/medarh.2020.74.228-232. [PMID: 32801441] - Nicholas G Larkins, Isaac D Liu, Narelle S Willis, Jonathan C Craig, Elisabeth M Hodson. Non-corticosteroid immunosuppressive medications for steroid-sensitive nephrotic syndrome in children.
The Cochrane database of systematic reviews.
2020 04; 4(?):CD002290. doi:
10.1002/14651858.cd002290.pub5. [PMID: 32297308] - WanJun Lu, ShuHao Gong, Juan Li, HongWen Luo, Ying Wang. Efficacy and safety of rituximab in the treatment of membranous nephropathy: A systematic review and meta-analysis.
Medicine.
2020 Apr; 99(16):e19804. doi:
10.1097/md.0000000000019804. [PMID: 32311997] - Luis D Pedro-Hernández, Ulises Organista-Mateos, Luis I Allende-Alarcón, Elena Martínez-Klimova, Teresa Ramírez-Ápan, Marcos Martínez-García. Improvement of the Anticancer Activity of Chlorambucil and Ibuprofen via Calix[4]arene Conjugates.
Medicinal chemistry (Shariqah (United Arab Emirates)).
2020; 16(7):984-990. doi:
10.2174/1573406415666190826162339. [PMID: 31448714] - Leila Tabrizi, Lukman O Olasunkanmi, Olatomide A Fadare. De novo design of thioredoxin reductase-targeted heterometallic titanocene-gold compounds of chlorambucil for mechanistic insights into renal cancer.
Chemical communications (Cambridge, England).
2019 Dec; 56(2):297-300. doi:
10.1039/c9cc07406f. [PMID: 31808475] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - Kogularasu Sakthivel, Akilarasan Muthumariappan, Shen-Ming Chen, Yi-Ling Li, Tse-Wei Chen, Mohammad Ajmal Ali. Evaluating Ternary Metal Oxide (TMO) core-shell nanocomposites for the rapid determination of the anti-neoplastic drug Chlorambucil (Leukeran™) by electrochemical approaches.
Materials science & engineering. C, Materials for biological applications.
2019 Oct; 103(?):109724. doi:
10.1016/j.msec.2019.05.009. [PMID: 31349448] - Anazoeze Jude Madu, Kaladada Korubo, Augustine Okoye, Ifeoma Ajuba, Augustine N Duru, Angela O Ugwu, Oji Nnachi, Helen Chioma Okoye. Presenting features and treatment outcomes of chronic lymphocytic leukaemia in a resource poor Southern Nigeria.
Malawi medical journal : the journal of Medical Association of Malawi.
2019 06; 31(2):144-149. doi:
10.4314/mmj.v31i2.7. [PMID: 31452848] - Andrea Angioi, Nicola Lepori, Ana Coloma López, Sanjeev Sethi, Fernando C Fervenza, Antonello Pani. Treatment of primary membranous nephropathy: where are we now?.
Journal of nephrology.
2018 08; 31(4):489-502. doi:
10.1007/s40620-017-0427-5. [PMID: 28875476] - R Timothy Bentley, Stephanie A Thomovsky, Margaret A Miller, Deborah W Knapp, Aaron A Cohen-Gadol. Canine (Pet Dog) Tumor Microsurgery and Intratumoral Concentration and Safety of Metronomic Chlorambucil for Spontaneous Glioma: A Phase I Clinical Trial.
World neurosurgery.
2018 Aug; 116(?):e534-e542. doi:
10.1016/j.wneu.2018.05.027. [PMID: 29775768] - Margaux Van Wynsberghe, Pascal Lenain, Fanny Drieux, Dominique Guerrot, Dominique Bertrand. Monoclonal B lymphocytosis and minimal change disease: a new monoclonal B-cell disorder of renal significance?.
Journal of nephrology.
2018 04; 31(2):317-320. doi:
10.1007/s40620-017-0464-0. [PMID: 29270844] - Yvonne A Dei-Adomakoh, Leslie Quarcoopome, Afua D Abrahams, Catherine I Segbefia, Dzifa I Dey. Sjögren's and plasma cell variant Castleman disease: a case report.
Ghana medical journal.
2018 Mar; 52(1):61-65. doi:
10.4314/gmj.v52i1.9. [PMID: 30013261] - Michael J Reese, Deborah W Knapp, Kimberly M Anderson, Julie A Mund, Jamie Case, David R Jones, Rebecca A Packer. In vitro effect of chlorambucil on human glioma cell lines (SF767 and U87-MG), and human microvascular endothelial cell (HMVEC) and endothelial progenitor cells (ECFCs), in the context of plasma chlorambucil concentrations in tumor-bearing dogs.
PloS one.
2018; 13(9):e0203517. doi:
10.1371/journal.pone.0203517. [PMID: 30192852] - Quan Zhang, Li Zhang, Zemin Li, Xingliang Xie, Xiurong Gao, Xiaohong Xu. Inducing Controlled Release and Increased Tumor-Targeted Delivery of Chlorambucil via Albumin/Liposome Hybrid Nanoparticles.
AAPS PharmSciTech.
2017 Nov; 18(8):2977-2986. doi:
10.1208/s12249-017-0782-5. [PMID: 28477146] - Sierra Schmidt, Mark Sears, Stephanie Crawford, Christine Cicci, Charles J Diskin. Membranous Glomerulopathy in Hypogammaglobulinemia.
The American journal of the medical sciences.
2017 Mar; 353(3):307-309. doi:
10.1016/j.amjms.2016.12.017. [PMID: 28262220] - Simon J A van Kuijk, Nanda Kumar Parvathaneni, Raymon Niemans, Marike W van Gisbergen, Fabrizio Carta, Daniela Vullo, Silvia Pastorekova, Ala Yaromina, Claudiu T Supuran, Ludwig J Dubois, Jean-Yves Winum, Philippe Lambin. New approach of delivering cytotoxic drugs towards CAIX expressing cells: A concept of dual-target drugs.
European journal of medicinal chemistry.
2017 Feb; 127(?):691-702. doi:
10.1016/j.ejmech.2016.10.037. [PMID: 27823879] - Jianguo Lin, Ling Qiu, Gaochao Lv, Ke Li, Wei Wang, Guiqing Liu, Xueyu Zhao, Shanshan Wang. Synthesis and preliminary biological evaluation of a 99m Tc-chlorambucil derivative as a potential tumor imaging agent.
Journal of labelled compounds & radiopharmaceuticals.
2017 02; 60(2):116-123. doi:
10.1002/jlcr.3481. [PMID: 27862213] - Song Ren, Ying Wang, Li Xian, Tadashi Toyama, Meg Jardine, Guisen Li, Vlado Perkovic, Daqing Hong. Comparative effectiveness and tolerance of immunosuppressive treatments for idiopathic membranous nephropathy: A network meta-analysis.
PloS one.
2017; 12(9):e0184398. doi:
10.1371/journal.pone.0184398. [PMID: 28898290] - Natalie C Reinert, David G Feldman. Acquired Fanconi syndrome in four cats treated with chlorambucil.
Journal of feline medicine and surgery.
2016 12; 18(12):1034-1040. doi:
10.1177/1098612x15593108. [PMID: 26170278] - Nannan Pang, Rui Zhang, Jinhua Li, Zhenghao Zhang, Hailong Yuan, Gang Chen, Fang Zhao, Lei Wang, Haizhou Cao, Jianhua Qu, Jianbing Ding. Increased IL-10/IL-17 ratio is aggravated along with the prognosis of patients with chronic lymphocytic leukemia.
International immunopharmacology.
2016 Nov; 40(?):57-64. doi:
10.1016/j.intimp.2016.07.008. [PMID: 27584054] - Carmen Diana Herling, Marion Klaumünzer, Cristiano Krings Rocha, Janine Altmüller, Holger Thiele, Jasmin Bahlo, Sandra Kluth, Giuliano Crispatzu, Marco Herling, Joanna Schiller, Anja Engelke, Eugen Tausch, Hartmut Döhner, Kirsten Fischer, Valentin Goede, Peter Nürnberg, Hans Christian Reinhardt, Stephan Stilgenbauer, Michael Hallek, Karl-Anton Kreuzer. Complex karyotypes and KRAS and POT1 mutations impact outcome in CLL after chlorambucil-based chemotherapy or chemoimmunotherapy.
Blood.
2016 07; 128(3):395-404. doi:
10.1182/blood-2016-01-691550. [PMID: 27226433] - Vanja Vučičević Boras, Snježana Židovec-Lepej, Branka Marinović, Sven Seiwerth, Ivana Škrinjar, Dražen Pulanić, Danica Vidović Juras. DRUG-INDUCED ORAL ULCERATIONS: CASE REPORT.
Acta clinica Croatica.
2016 Jun; 55(2):334-7. doi:
10.20471/acc.2016.55.02.24. [PMID: 28394553] - Temilolu Idowu, Pranati Samadder, Gilbert Arthur, Frank Schweizer. Design, synthesis and antitumor properties of glycosylated antitumor ether lipid (GAEL)- chlorambucil-hybrids.
Chemistry and physics of lipids.
2016 Jan; 194(?):139-48. doi:
10.1016/j.chemphyslip.2015.07.003. [PMID: 26188768] - Mina Ibrahim Tadros, Abdulaziz Mohsen Al-Mahallawi. Long-circulating lipoprotein-mimic nanoparticles for smart intravenous delivery of a practically-insoluble antineoplastic drug: Development, preliminary safety evaluations and preclinical pharmacokinetic studies.
International journal of pharmaceutics.
2015 Sep; 493(1-2):439-50. doi:
10.1016/j.ijpharm.2015.08.011. [PMID: 26253380] - Mei-Hong Li, Rolf Swenson, Miriam Harel, Sampa Jana, Erik Stolarzewicz, Timothy Hla, Linda H Shapiro, Fernando Ferrer. Antitumor Activity of a Novel Sphingosine-1-Phosphate 2 Antagonist, AB1, in Neuroblastoma.
The Journal of pharmacology and experimental therapeutics.
2015 Sep; 354(3):261-8. doi:
10.1124/jpet.115.224519. [PMID: 26105954] - Venkata V V R Marada, Saskia Flörl, Annett Kühne, Gerhard Burckhardt, Yohannes Hagos. Interaction of human organic anion transporter polypeptides 1B1 and 1B3 with antineoplastic compounds.
European journal of medicinal chemistry.
2015 Mar; 92(?):723-31. doi:
10.1016/j.ejmech.2015.01.011. [PMID: 25618019] - Yohannes Hagos, Philip Hundertmark, Volodymyr Shnitsar, Venkata V V R Marada, Gerald Wulf, Gerhard Burckhardt. Renal human organic anion transporter 3 increases the susceptibility of lymphoma cells to bendamustine uptake.
American journal of physiology. Renal physiology.
2015 Feb; 308(4):F330-8. doi:
10.1152/ajprenal.00467.2014. [PMID: 25477469] - Jinyao Liu, Wenge Liu, Isaac Weitzhandler, Jayanta Bhattacharyya, Xinghai Li, Jing Wang, Yizhi Qi, Somnath Bhattacharjee, Ashutosh Chilkoti. Ring-opening polymerization of prodrugs: a versatile approach to prepare well-defined drug-loaded nanoparticles.
Angewandte Chemie (International ed. in English).
2015 Jan; 54(3):1002-6. doi:
10.1002/anie.201409293. [PMID: 25427831] - Nao Nagata, Sanae Shibata, Hiroki Sakai, Hiroaki Konno, Satoshi Takashima, Mifumi Kawabe, Takashi Mori, Hitoshi Kitagawa, Makoto Washizu. Gallbladder lymphoma in a miniature dachshund.
The Journal of veterinary medical science.
2015 Jan; 77(1):117-21. doi:
10.1292/jvms.14-0300. [PMID: 25311915] - XinYi Wang, Quan Zhang, Qing Lin, Yue Zhang, Zhi-Rong Zhang. Validated LC-MS/MS method for the simultaneous determination of chlorambucil and its prodrug in mouse plasma and brain, and application to pharmacokinetics.
Journal of pharmaceutical and biomedical analysis.
2014 Oct; 99(?):74-8. doi:
10.1016/j.jpba.2014.07.010. [PMID: 25090578] - Avijit Jana, Kim Truc Nguyen, Xin Li, Pengcheng Zhu, Nguan Soon Tan, Hans Ågren, Yanli Zhao. Perylene-derived single-component organic nanoparticles with tunable emission: efficient anticancer drug carriers with real-time monitoring of drug release.
ACS nano.
2014 Jun; 8(6):5939-52. doi:
10.1021/nn501073x. [PMID: 24824959] - Suravi Kalita, Akalesh Kumar Verma, Surya Bali Prasad. Chlorambucil and ascorbic acid-mediated anticancer activity and hematological toxicity in Dalton's ascites lymphoma-bearing mice.
Indian journal of experimental biology.
2014 Feb; 52(2):112-24. doi:
. [PMID: 24597143] - Nanthiya Pravitsitthikul, Narelle S Willis, Elisabeth M Hodson, Jonathan C Craig. Non-corticosteroid immunosuppressive medications for steroid-sensitive nephrotic syndrome in children.
The Cochrane database of systematic reviews.
2013 Oct; ?(10):CD002290. doi:
10.1002/14651858.cd002290.pub4. [PMID: 24166716] - Julien R S Dandrieux, Peter-John M Noble, Timothy J Scase, Peter J Cripps, Alexander J German. Comparison of a chlorambucil-prednisolone combination with an azathioprine-prednisolone combination for treatment of chronic enteropathy with concurrent protein-losing enteropathy in dogs: 27 cases (2007-2010).
Journal of the American Veterinary Medical Association.
2013 Jun; 242(12):1705-14. doi:
10.2460/javma.242.12.1705. [PMID: 23725434] - Luis E Voyer, Caupolican Alvarado, Rubén J Cuttica, Alejandro Balestracci, Marta Zardini, Néstor Lago. Nephrotic syndrome due to immunoglobulin M mesangial glomerulonephritis preceding juvenile idiopathic arthritis.
Iranian journal of kidney diseases.
2013 May; 7(3):231-4. doi:
NULL. [PMID: 23689157] - Andrew Howman, Tracey L Chapman, Maria M Langdon, Caroline Ferguson, Dwomoa Adu, John Feehally, Gillian J Gaskin, David R W Jayne, Donal O'Donoghue, Michael Boulton-Jones, Peter W Mathieson. Immunosuppression for progressive membranous nephropathy: a UK randomised controlled trial.
Lancet (London, England).
2013 Mar; 381(9868):744-51. doi:
10.1016/s0140-6736(12)61566-9. [PMID: 23312808] - Wei Xin Li, Xiang Yan, Chun Rui Shi, Ai Ping Zhang. Chlorambucil for patients with primary biliary cirrhosis.
The Cochrane database of systematic reviews.
2012 Sep; ?(9):CD008714. doi:
10.1002/14651858.cd008714.pub2. [PMID: 22972125] - Heng Li, Xiangdong Shi, Hong Shen, Xiayu Li, Huiping Wang, Hongmei Li, Guangbiao Xu, Jianghua Chen. Tacrolimus versus intravenous pulse cyclophosphamide therapy in Chinese adults with steroid-resistant idiopathic minimal change nephropathy: a multicenter, open-label, nonrandomized cohort trial.
Clinical therapeutics.
2012 May; 34(5):1112-20. doi:
10.1016/j.clinthera.2012.03.008. [PMID: 22503105] - Katie J Baxter, Richard C Hill, Shannon L Parfitt, Clifford R Berry, Travis W Heskett, Barbara J Sheppard. Gastrointestinal small-cell lymphoma with gall bladder involvement in a cat.
Journal of feline medicine and surgery.
2012 Apr; 14(4):267-71. doi:
10.1177/1098612x11434820. [PMID: 22412164] - Lajos Gera, Caroline Roy, Marie-Thérèse Bawolak, Xavier Charest-Morin, François Marceau. N-terminal extended conjugates of the agonists and antagonists of both bradykinin receptor subtypes: structure-activity relationship, cell imaging using ligands conjugated with fluorophores and prospect for functionally active cargoes.
Peptides.
2012 Apr; 34(2):433-46. doi:
10.1016/j.peptides.2012.02.007. [PMID: 22349904] - Morie A Gertz. Waldenström macroglobulinemia.
Hematology (Amsterdam, Netherlands).
2012 Apr; 17 Suppl 1(?):S112-6. doi:
10.1179/102453312x13336169156212. [PMID: 22507796] - S Jennane, K Doghmi, E M Mahtat, N Messaoudi, B Varet, M Mikdame. Bing and neel syndrome.
Case reports in hematology.
2012; 2012(?):845091. doi:
10.1155/2012/845091. [PMID: 22988532] - Pius S Fasinu, Patrick J Bouic, Bernd Rosenkranz. An overview of the evidence and mechanisms of herb-drug interactions.
Frontiers in pharmacology.
2012; 3(?):69. doi:
10.3389/fphar.2012.00069. [PMID: 22557968] - A Gigante, E Rosato, M Liberatori, M L Gasperini, K Giannakakis, B Barbano, R Cianci, F Salsano, A Amoroso. ACTH and azathioprine: antiproteinuric and lipid-lowering effect in the course of idiopathic membranous glomerulonephritis.
Journal of biological regulators and homeostatic agents.
2012 Jan; 26(1):135-8. doi:
. [PMID: 22475105] - Emily P McQuarrie, Catherine M Stirling, Colin C Geddes. Idiopathic membranous nephropathy and nephrotic syndrome: outcome in the era of evidence-based therapy.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
2012 Jan; 27(1):235-42. doi:
10.1093/ndt/gfr220. [PMID: 21558430] - Jie Xu, Ji-Hui Zhao, Ying Liu, Nian-Ping Feng, Yong-Tai Zhang. RGD-modified poly(D,L-lactic acid) nanoparticles enhance tumor targeting of oridonin.
International journal of nanomedicine.
2012; 7(?):211-9. doi:
10.2147/ijn.s27581. [PMID: 22275836] - Guoqiang Xie, Jing Xu, Chaoyang Ye, Dongping Chen, Chenggang Xu, Li Yang, Yiyi Ma, Xiaohong Hu, Lin Li, Lijun Sun, Xuezhi Zhao, Zhiguo Mao, Changlin Mei. Immunosuppressive treatment for nephrotic idiopathic membranous nephropathy: a meta-analysis based on Chinese adults.
PloS one.
2012; 7(9):e44330. doi:
10.1371/journal.pone.0044330. [PMID: 22957065] - Eric Wallace, Agnes B Fogo, Gerald Schulman. Imatinib therapy for non-infection-related type II cryoglobulinemia with membranoproliferative glomerulonephritis.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
2012 Jan; 59(1):122-5. doi:
10.1053/j.ajkd.2011.08.016. [PMID: 21982457] - Iryna N Stepanenko, Angela Casini, Fabio Edafe, Maria S Novak, Vladimir B Arion, Paul J Dyson, Michael A Jakupec, Bernhard K Keppler. Conjugation of organoruthenium(II) 3-(1H-benzimidazol-2-yl)pyrazolo[3,4-b]pyridines and indolo[3,2-d]benzazepines to recombinant human serum albumin: a strategy to enhance cytotoxicity in cancer cells.
Inorganic chemistry.
2011 Dec; 50(24):12669-79. doi:
10.1021/ic201801e. [PMID: 22111668] - Anna Osofsky, Michelle G Hawkins, Oded Foreman, Michael S Kent, William Vernau, Linda J Lowenstine. T-cell chronic lymphocytic leukemia in a double yellow-headed Amazon parrot (Amazona ochrocephala oratrix).
Journal of avian medicine and surgery.
2011 Dec; 25(4):286-94. doi:
10.1647/2011-009.1. [PMID: 22458185] - Xianrui Dou, Haitang Hu, Yongle Ju, Yongdong Liu, Kaifu Kang, Shufeng Zhou, Wenfang Chen. Concurrent nephrotic syndrome and acute renal failure caused by chronic lymphocytic leukemia (CLL): a case report and literature review.
Diagnostic pathology.
2011 Oct; 6(?):99. doi:
10.1186/1746-1596-6-99. [PMID: 21995711] - Francesca Merchionne, Pasquale Procaccio, Franco Dammacco. Waldenström's macroglobulinemia. An overview of its clinical, biochemical, immunological and therapeutic features and our series of 121 patients collected in a single center.
Critical reviews in oncology/hematology.
2011 Oct; 80(1):87-99. doi:
10.1016/j.critrevonc.2010.09.007. [PMID: 21036057] - Jonathan Hebb, Sarit Assouline, Caroline Rousseau, Pierre Desjardins, Stephen Caplan, Merrill J Egorin, Lilian Amrein, Raquel Aloyz, Lawrence Panasci. A phase I study of imatinib mesylate in combination with chlorambucil in previously treated chronic lymphocytic leukemia patients.
Cancer chemotherapy and pharmacology.
2011 Sep; 68(3):643-51. doi:
10.1007/s00280-010-1530-7. [PMID: 21120481] - Laetitia Jaillardon, Corinne Fournel-Fleury. Waldenström's macroglobulinemia in a dog with a bleeding diathesis.
Veterinary clinical pathology.
2011 Sep; 40(3):351-5. doi:
10.1111/j.1939-165x.2011.00341.x. [PMID: 21827519] - Wenyan Xiao, Ganchimeg Ishdorj, Jinmei Sun, James B Johnston, Spencer B Gibson. Death receptor 4 is preferentially recruited to lipid rafts in chronic lymphocytic leukemia cells contributing to tumor necrosis related apoptosis inducing ligand-induced synergistic apoptotic responses.
Leukemia & lymphoma.
2011 Jul; 52(7):1290-301. doi:
10.3109/10428194.2011.567317. [PMID: 21699383] - Howard Trachtman, Fernando C Fervenza, Debbie S Gipson, Peter Heering, David R W Jayne, Harm Peters, Stefano Rota, Giuseppe Remuzzi, L Christian Rump, Lorenz K Sellin, Jeremy P W Heaton, James B Streisand, Marjie L Hard, Steven R Ledbetter, Flavio Vincenti. A phase 1, single-dose study of fresolimumab, an anti-TGF-β antibody, in treatment-resistant primary focal segmental glomerulosclerosis.
Kidney international.
2011 Jun; 79(11):1236-43. doi:
10.1038/ki.2011.33. [PMID: 21368745] - Ramón Peces, Jorge Martínez-Ara, Carlos Peces, Mariluz Picazo, Emilio Cuesta-López, Cristina Vega, Sebastián Azorín, Rafael Selgas. Nephrotic syndrome and idiopathic membranous nephropathy associated with autosomal-dominant polycystic kidney disease.
TheScientificWorldJournal.
2011 May; 11(?):1041-7. doi:
10.1100/tsw.2011.94. [PMID: 21552769] - Anders Carlsson, Dirk M Wuttge, Johan Ingvarsson, Anders A Bengtsson, Gunnar Sturfelt, Carl A K Borrebaeck, Christer Wingren. Serum protein profiling of systemic lupus erythematosus and systemic sclerosis using recombinant antibody microarrays.
Molecular & cellular proteomics : MCP.
2011 May; 10(5):M110.005033. doi:
10.1074/mcp.m110.005033. [PMID: 21350050] - Milena Villarini, Luca Dominici, Renza Piccinini, Cristina Fatigoni, Maura Ambrogi, Gianluca Curti, Piero Morucci, Giacomo Muzi, Silvano Monarca, Massimo Moretti. Assessment of primary, oxidative and excision repaired DNA damage in hospital personnel handling antineoplastic drugs.
Mutagenesis.
2011 May; 26(3):359-69. doi:
10.1093/mutage/geq102. [PMID: 21112930] - Satish V Khadilkar, Shrikant S Deshmukh, Pramod D Dhonde. Chronic dysimmune neuropathies: Beyond chronic demyelinating polyradiculoneuropathy.
Annals of Indian Academy of Neurology.
2011 Apr; 14(2):81-92. doi:
10.4103/0972-2327.82789. [PMID: 21808468] - Pierre-Antoine Michel, Karine Dahan, Pierre-Yves Ancel, Emmanuelle Plaisier, Rachid Mojaat, Sophie De Seigneux, Eric Daugas, Marie Matignon, Laurent Mesnard, Alexandre Karras, Hélène François, Agathe Pardon, Valérie Caudwell, Hanna Debiec, Pierre Ronco. Rituximab treatment for membranous nephropathy: a French clinical and serological retrospective study of 28 patients.
Nephron extra.
2011 Jan; 1(1):251-61. doi:
10.1159/000333068. [PMID: 22470399] - Banasri Hazra, Subhalakshmi Ghosh, Amit Kumar, B N Pandey. The prospective role of plant products in radiotherapy of cancer: a current overview.
Frontiers in pharmacology.
2011; 2(?):94. doi:
10.3389/fphar.2011.00094. [PMID: 22291649] - Fakhry S Salem, Mohamed O T Badr, Ahmed N F Neamat-Allah. Biochemical and pathological studies on the effects of levamisole and chlorambucil on Ehrlich ascites carcinoma-bearing mice.
Veterinaria italiana.
2011 Jan; 47(1):89-95. doi:
. [PMID: 21240854] - Yoshinori Takeuchi, Haruna Iizuka, Hiroyuki Kanemitsu, Yasuhito Fujino, Ko Nakashima, Kazuyuki Uchida, Koichi Ohno, Hiroyuki Nakayama, Hajime Tsujimoto. Myeloma-related disorder with leukaemic progression in a cat.
Journal of feline medicine and surgery.
2010 Dec; 12(12):982-7. doi:
10.1016/j.jfms.2010.07.018. [PMID: 21036087] - Honglin Song, Shufang Nie, Xinggang Yang, Ning Li, Hongtao Xu, Liangyuan Zheng, Weisan Pan. Characterization and in vivo evaluation of novel lipid-chlorambucil nanospheres prepared using a mixture of emulsifiers for parenteral administration.
International journal of nanomedicine.
2010 Nov; 5(?):933-42. doi:
10.2147/ijn.s14596. [PMID: 21187945] - Cristiana Rollino, Rosanna Coppo, Franca Giacchino, Silvana Savoldi, Marco Manganaro, Alessandro Amore, Loredana Colla, Michela Ferro, Giovanni Demicheli, Silvia Berutti, Manuel Burdese, Giuseppe Paternoster, Raffaella Cravero, Luisa Benozzi, Giuseppe Vagelli, Alessandra Messuerotti, Carolina Licata, Serena Bainotti, Rosaria Rita Patti, Marco Quaglia, Luigia Costantini, Piero Stratta, Giuseppe Segoloni. [Application of guidelines in clinical practice: a multicenter analysis of the treatment of membranous glomerulonephritis in Piedmont, Italy].
Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia.
2010 Nov; 27(6):639-48. doi:
NULL. [PMID: 21132646] - R Naumovic, D Furuncic, D Jovanovic, M Stosovic, G Basta-Jovanovic, V Lezaic. Application of artificial neural networks in estimating predictive factors and therapeutic efficacy in idiopathic membranous nephropathy.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2010 Nov; 64(9):633-8. doi:
10.1016/j.biopha.2010.06.003. [PMID: 20888177] - J P Power, M El Chaar, J Temple, M Thomas, D Spillane, D Candotti, J P Allain. HBV reactivation after fludarabine chemotherapy identified on investigation of suspected transfusion-transmitted Hepatitis B virus.
Journal of hepatology.
2010 Oct; 53(4):780-7. doi:
10.1016/j.jhep.2010.04.034. [PMID: 20638744] - Anna Wasilewska, Agnieszka Rybi-Szuminska, Walentyna Zoch-Zwierz. Serum RANKL, osteoprotegerin (OPG), and RANKL/OPG ratio in nephrotic children.
Pediatric nephrology (Berlin, Germany).
2010 Oct; 25(10):2067-75. doi:
10.1007/s00467-010-1583-1. [PMID: 20602239] - Gustavo Horacio Marin, Eduardo Mansilla. Apoptosis induced by Magnolia Grandiflora extract in chlorambucil-resistant B-chronic lymphocytic leukemia cells.
Journal of cancer research and therapeutics.
2010 Oct; 6(4):463-5. doi:
10.4103/0973-1482.77107. [PMID: 21358081] - Angoori Gnaneshwar Rao. Cryoglobulinemia in a child.
Indian journal of dermatology.
2010 Oct; 55(4):381-3. doi:
10.4103/0019-5154.74558. [PMID: 21430896] - A Eyshi Oskooii, L Mohammad Gholizad, S Zare, V Nejati. A comparison of effects of ABVD and ChlVPP chemotherapeutic protocols for Hodgkin's disease on rats' epididiymal and testicular tissues.
Pakistan journal of biological sciences : PJBS.
2010 Sep; 13(18):884-90. doi:
10.3923/pjbs.2010.884.890. [PMID: 23350161] - Jameela A Kari, Manal Halawani. Treatment of steroid resistant nephrotic syndrome in children.
Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia.
2010 May; 21(3):484-7. doi:
NULL. [PMID: 20427873] - Jack Cheng, Tian-Huey Lu, Chao-Lin Liu, Jung-Yaw Lin. A biophysical elucidation for less toxicity of agglutinin than abrin-a from the seeds of Abrus precatorius in consequence of crystal structure.
Journal of biomedical science.
2010 Apr; 17(?):34. doi:
10.1186/1423-0127-17-34. [PMID: 20433687] - Ana Maria Carmona-Ribeiro. Biomimetic nanoparticles: preparation, characterization and biomedical applications.
International journal of nanomedicine.
2010 Apr; 5(?):249-59. doi:
10.2147/ijn.s9035. [PMID: 20463941] - M Harnalikar, S Pande, V Kharkar, U Khopkar. Keratotic vascular papules over the feet: a case of Waldenström's macroglobulinaemia-associated cutaneous macroglobulinosis.
Clinical and experimental dermatology.
2010 Apr; 35(3):278-81. doi:
10.1111/j.1365-2230.2009.03651.x. [PMID: 19874364] - Srinivas Ganta, Puneet Sharma, James W Paxton, Bruce C Baguley, Sanjay Garg. Pharmacokinetics and pharmacodynamics of chlorambucil delivered in long-circulating nanoemulsion.
Journal of drug targeting.
2010 Feb; 18(2):125-33. doi:
10.3109/10611860903244199. [PMID: 19728787] - Samuel Rivera, James R McClearen, Drury R Reavill. Treatment of nonepitheliotropic cutaneous B-cell lymphoma in an umbrella cockatoo (Cacatua alba).
Journal of avian medicine and surgery.
2009 Dec; 23(4):294-302. doi:
10.1647/2008-032r.1. [PMID: 20235461] - Xiaofan Sui, Jin Sun, Haiyan Li, Yongjun Wang, Jianfang Liu, Xiaohong Liu, Wenping Zhang, Lijiang Chen, Zhonggui He. Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
European journal of medicinal chemistry.
2009 Nov; 44(11):4455-60. doi:
10.1016/j.ejmech.2009.06.004. [PMID: 19586686] - Maria Hanna Kniazewska, Anna Karolina Obuchowicz, Tomasz Wielkoszyński, Joanna Zmudzińska-Kitczak, Katarzyna Urban, Lidia Hyla-Klekot. Evaluation of certain constituents of antioxidant defense in youth treated in the past for steroid-sensitive idiopathic nephrotic syndrome.
Pediatric nephrology (Berlin, Germany).
2009 Nov; 24(11):2187-92. doi:
10.1007/s00467-009-1269-8. [PMID: 19636593] - Ernest Hs Choy, Jessica E Hoogendijk, Bryan Lecky, John B Winer, Patrick Gordon. WITHDRAWN: Immunosuppressant and immunomodulatory treatment for dermatomyositis and polymyositis.
The Cochrane database of systematic reviews.
2009 Oct; ?(4):CD003643. doi:
10.1002/14651858.cd003643.pub3. [PMID: 19821312] - Vicki A Morrison. Infectious complications in patients with chronic lymphocytic leukemia: pathogenesis, spectrum of infection, and approaches to prophylaxis.
Clinical lymphoma & myeloma.
2009 Oct; 9(5):365-70. doi:
10.3816/clm.2009.n.071. [PMID: 19858055] - Hala Alshayeb, Barry M Wall. Non-Hodgkin's lymphoma associated membranoproliferative glomerulonephritis: rare case of long term remission with chemotherapy: a case report.
Cases journal.
2009 Sep; 2(?):7201. doi:
10.1186/1757-1626-0002-0000007201. [PMID: 20181193] - Simon Hohenester, Ronald P J Oude-Elferink, Ulrich Beuers. Primary biliary cirrhosis.
Seminars in immunopathology.
2009 Sep; 31(3):283-307. doi:
10.1007/s00281-009-0164-5. [PMID: 19603170] - Manthena V S Varma, Bo Feng, R Scott Obach, Matthew D Troutman, Jonathan Chupka, Howard R Miller, Ayman El-Kattan. Physicochemical determinants of human renal clearance.
Journal of medicinal chemistry.
2009 Aug; 52(15):4844-52. doi:
10.1021/jm900403j. [PMID: 19445515] - K S Wilson. Regression of follicular lymphoma with Devil's Claw: coincidence or causation?.
Current oncology (Toronto, Ont.).
2009 Aug; 16(4):67-70. doi:
10.3747/co.v16i4.401. [PMID: 19672427] - Arnaud Millet, Nathalie Rioux-Leclercq, Jean-Pierre Le Lay, Patrick Le Pogamp, Cécile Vigneau. Unexpected remission of renal AA amyloidosis associated with rheumatoid arthritis.
Joint bone spine.
2009 Jul; 76(4):431-2. doi:
10.1016/j.jbspin.2008.12.003. [PMID: 19303340] - Palle J Pedersen, Mikkel S Christensen, Tristan Ruysschaert, Lars Linderoth, Thomas L Andresen, Fredrik Melander, Ole G Mouritsen, Robert Madsen, Mads H Clausen. Synthesis and biophysical characterization of chlorambucil anticancer ether lipid prodrugs.
Journal of medicinal chemistry.
2009 May; 52(10):3408-15. doi:
10.1021/jm900091h. [PMID: 19402667] - U Das, K V Dakshinamurty, N Prasad. Ponticelli regimen in idiopathic nephrotic syndrome.
Indian journal of nephrology.
2009 Apr; 19(2):48-52. doi:
10.4103/0971-4065.53321. [PMID: 20368923] - Saman Hewamana, Chris Pepper, Chris Jenkins, Clare Rowntree. Acute renal failure as the presenting feature of leukaemic infiltration in chronic lymphocytic leukaemia.
Clinical and experimental nephrology.
2009 Apr; 13(2):179-181. doi:
10.1007/s10157-009-0129-y. [PMID: 19255826]