3-[[(2S)-2,4-Dihydroxy-3,3-dimethylbutanoyl]amino]propanoic acid (BioDeep_00000177899)

Main id: BioDeep_00000000742

 

human metabolite PANOMIX_OTCML-2023 blood metabolite BioNovoGene_Lab2019


代谢物信息卡片


3-[[(2S)-2,4-Dihydroxy-3,3-dimethylbutanoyl]amino]propanoic acid

化学式: C9H17NO5 (219.11066720000002)
中文名称: D-泛酸, 泛酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C)(CO)C(C(=O)NCCC(=O)O)O
InChI: InChI=1S/C9H17NO5/c1-9(2,5-11)7(14)8(15)10-4-3-6(12)13/h7,11,14H,3-5H2,1-2H3,(H,10,15)(H,12,13)

描述信息

Pantothenic acid is a water-soluble vitamin. For many animals, pantothenic acid is an essential nutrient. Only the dextrorotatory (D) isomer of pantothenic acid possesses biologic activity. The levorotatory (L) form may antagonize the effects of the dextrorotatory isomer. Pantothenic acid is found in many foods, some of which are cream substitute, yellow bell pepper, corn, and atlantic mackerel.
D018977 - Micronutrients > D014815 - Vitamins
D-Pantothenic acid (Pantothenate) is an essential trace nutrient that functions as the obligate precursor of coenzyme A (CoA). D-Pantothenic acid plays key roles in myriad biological processes, including many that regulate carbohydrate, lipid, protein, and nucleic acid metabolism[1].
D-Pantothenic acid (Pantothenate) is an essential trace nutrient that functions as the obligate precursor of coenzyme A (CoA). D-Pantothenic acid plays key roles in myriad biological processes, including many that regulate carbohydrate, lipid, protein, and nucleic acid metabolism[1].

同义名列表

22 个代谢物同义名

3-[[(2S)-2,4-Dihydroxy-3,3-dimethylbutanoyl]amino]propanoic acid; D(+)-N-(2,4-Dihydroxy-3,3-dimethylbutyryl)-beta-alanine; 3-(2,4-dihydroxy-3,3-dimethylbutanamido)propanoic acid; D(+)-N-(2,4-Dihydroxy-3,3-dimethylbutyryl)-b-alanine; N-(2,4-dihydroxy-3,3-dimethylbutanoyl)-beta-alanine; N-(2,4-Dihydroxy-3,3-dimethylbutanoyl)-β-alanine; N-(2,4-Dihydroxy-3,3-dimethylbutanoyl)-b-alanine; Chick antidermatitis factor; (D)-(+)-Pantothenic acid; delta-Pantothenic acid; (D)-(+)-Pantothenate; (+)-Pantothenic acid; D-Pantothenic acid; delta-Pantothenate; (R)-pantothenate; Pantothenic Acid; (+)-Pantothenate; DL-Pantothenate; d-pantothenate; pantothenate; vitamin B5; Pantothenate



数据库引用编号

19 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yangyang Sun, Yutong Zhou, Qiyuan Long, Junwei Xing, Peizhen Guo, Yanchen Liu, Changjian Zhang, Yuanyuan Zhang, Alisdair R Fernie, Yuheng Shi, Yuehua Luo, Jie Luo, Cheng Jin. OsBCAT2, a gene responsible for the degradation of branched-chain amino acids, positively regulates salt tolerance by promoting the synthesis of vitamin B5. The New phytologist. 2024 Mar; 241(6):2558-2574. doi: 10.1111/nph.19551. [PMID: 38258425]
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  • Aitor Benedicto, Iera Hernandez-Unzueta, Eduardo Sanz, Joana Márquez. Ocoxin Increases the Antitumor Effect of BRAF Inhibition and Reduces Cancer Associated Fibroblast-Mediated Chemoresistance and Protumoral Activity in Metastatic Melanoma. Nutrients. 2021 Feb; 13(2):. doi: 10.3390/nu13020686. [PMID: 33669949]
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