beta-Amyrin acetate (BioDeep_00000176616)

Main id: BioDeep_00000396507

 

human metabolite PANOMIX_OTCML-2023 blood metabolite natural product


代谢物信息卡片


4,4,6a,6b,8a,11,11,14b-octamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-yl acetate

化学式: C32H52O2 (468.3967)
中文名称: β-香树脂醇乙酸酯
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1[C@@H](C([C@H]2[C@](C1)([C@@H]1[C@@](CC2)([C@]2(C(=CC1)[C@H]1[C@@](CC2)(CCC(C1)(C)C)C)C)C)C)(C)C)OC(=O)C
InChI: InChI=1S/C32H52O2/c1-21(33)34-26-13-14-30(7)24(28(26,4)5)12-15-32(9)25(30)11-10-22-23-20-27(2,3)16-17-29(23,6)18-19-31(22,32)8/h10,23-26H,11-20H2,1-9H3

描述信息

Beta-amyrin acetate, also known as B-amyrin acetic acid, is a member of the class of compounds known as triterpenoids. Triterpenoids are terpene molecules containing six isoprene units. Beta-amyrin acetate is practically insoluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). Beta-amyrin acetate can be found in burdock and guava, which makes beta-amyrin acetate a potential biomarker for the consumption of these food products.
β-Amyrin acetate is a triterpenoid with potent anti-inflammatory, antifungal, anti-diabetic, anti-hyperlipidemic activities. β-Amyrin acetate can inhibit HMG-CoA reductase activity by locating in the hydrophobic binding cleft of HMG CoA reductase[1][2][3][4].

同义名列表

12 个代谢物同义名

4,4,6a,6b,8a,11,11,14b-octamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-icosahydropicen-3-yl acetate; (4,4,6a,6b,8a,11,11,14b-Octamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl) acetate; 4,4,6a,6b,8a,11,11,14b-octamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl acetate; (3beta)-olean-12-en-3-yl acetate; beta-Amyrin acetic acid; alpha-amyrin acetate; b-Amyrin acetic acid; Β-amyrin acetic acid; beta-Amyrin acetate; β-Amyrin acetate; b-Amyrin acetate; amyrin acetate



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

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314 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Dae-Gun Seo, Sunggun Kim, Da Kyung Lee, Na Yeon Kim, Jae-Sun Lee, Kwang Woo Hwang, So-Young Park. Inhibitory effect of α-amyrin acetate isolated from Fraxinus rhynchophylla on Th17 polarization. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2019 Oct; 63(?):153056. doi: 10.1016/j.phymed.2019.153056. [PMID: 31398661]
  • Nkeoma Nkasi Okoye, Daniel Lotanna Ajaghaku, Henry Nnaemeka Okeke, Emmanuel Emeka Ilodigwe, Chukwuemeka Sylvester Nworu, Festus Basden C Okoye. beta-Amyrin and alpha-amyrin acetate isolated from the stem bark of Alstonia boonei display profound anti-inflammatory activity. Pharmaceutical biology. 2014 Nov; 52(11):1478-86. doi: 10.3109/13880209.2014.898078. [PMID: 25026352]
  • D Ramasamy, A Saraswathy. Vitiquinolone--a quinolone alkaloid from Hibiscus vitifolius Linn. Food chemistry. 2014 Feb; 145(?):970-5. doi: 10.1016/j.foodchem.2013.08.128. [PMID: 24128571]
  • Niaz Ali. Brine shrimp cytotoxicity of crude methanol extract and antispasmodic activity of α-amyrin acetate from Tylophora hirsuta wall. BMC complementary and alternative medicine. 2013 Jun; 13(?):135. doi: 10.1186/1472-6882-13-135. [PMID: 23773697]
  • Catharina E Fingolo, Thabata de S Santos, Marcelo D M Vianna Filho, Maria Auxiliadora C Kaplan. Triterpene esters: natural products from Dorstenia arifolia (Moraceae). Molecules (Basel, Switzerland). 2013 Apr; 18(4):4247-56. doi: 10.3390/molecules18044247. [PMID: 23579992]
  • Sanjay Kumar Karan, Arijit Mondal, Sagar Kumar Mishra, Dilipkumar Pal, Kedar Kumar Rout. Antidiabetic effect of Streblus asper in streptozotocin-induced diabetic rats. Pharmaceutical biology. 2013 Mar; 51(3):369-75. doi: 10.3109/13880209.2012.730531. [PMID: 23406357]
  • Ranjani Maurya, Anuj Srivastava, Priyanka Shah, Mohammad Imran Siddiqi, S M Rajendran, Anju Puri, Prem P Yadav. β-Amyrin acetate and β-amyrin palmitate as antidyslipidemic agents from Wrightia tomentosa leaves. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2012 Jun; 19(8-9):682-5. doi: 10.1016/j.phymed.2012.03.013. [PMID: 22541636]
  • Yong-Qin Yin, Zhi-Bin Shen, Ling-Yi Kong. [Chemical constituents from the tubers of Ipomoea batata]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2012 Jun; 35(6):913-7. doi: ". [PMID: 23236827]
  • Qi-kang Ya, Wen-jie Lu, Jia-yuan Chen, Xiao Tan. [Studies on the chemical constituents from the antithrombus activity extract of Radix Aerio Fici Microcarpae]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2010 Aug; 33(8):1254-6. doi: ". [PMID: 21213536]
  • Yan Ding, Chun Liang, Jun Ho Kim, Young-Mi Lee, Jae-Hee Hyun, Hee-Kyoung Kang, Jeong-Ah Kim, Byung Sun Min, Young Ho Kim. Triterpene compounds isolated from Acer mandshuricum and their anti-inflammatory activity. Bioorganic & medicinal chemistry letters. 2010 Mar; 20(5):1528-31. doi: 10.1016/j.bmcl.2010.01.096. [PMID: 20153184]
  • Qian Cai, Yu-qiang Liu, Xue Feng. [Studies on the chemical constituents from the seed of Forsythia suspense]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2009 Nov; 32(11):1691-3. doi: ". [PMID: 20218291]
  • Min-Qing Tian, Guang-Ming Bao, Nai-Yun Ji, Xiao-Ming Li, Bin-Gui Wang. [Triterpenoids and steroids from Excoecaria agallocha]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2008 Feb; 33(4):405-8. doi: ". [PMID: 18533497]
  • Ying Yuan, Wei-Dong Zhang, Chuan Zhang, Run-Hui Liu, Juan Su, Hui-Zi Jin. [Studies on chemical constituents from root of Cynanchum atratum]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2007 Sep; 32(18):1895-8. doi: . [PMID: 18051900]
  • Jules-Roger Kuiate, Simplice Mouokeu, Hypolyte K Wabo, Pierre Tane. Antidermatophytic triterpenoids from Syzygium jambos (L.) Alston (Myrtaceae). Phytotherapy research : PTR. 2007 Feb; 21(2):149-52. doi: 10.1002/ptr.2039. [PMID: 17128435]
  • Jun-Yan Wu, Guo-Cheng Li, Ding-Yong Wang. [Chemical constituents of the non-alkaloid fraction of Uncaria macrophylla]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. 2007 Feb; 27(2):226-7. doi: ". [PMID: 17355944]
  • Zhong Dai, Feng Wang, Gang-Li Wang, Rui-Chao Lin. [Studies on chemical constituents of Balanophora spicata]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2006 Nov; 31(21):1798-800. doi: ". [PMID: 17260797]
  • Jian-feng Zhang, You-bin Li, Cheng-lu Li, Jian-qin Jiang. [Studies on chemical constituents in root tuber of Cynanchum auriculatum]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2006 May; 31(10):814-6. doi: ". [PMID: 17048663]
  • Xing-qi Tan, Hai-sheng Chen, Cong-li Xu, Run-hui Liu, Wei-dong Xuan. [Studies on chemical constituents of Ervatamia hainanensis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2003 Nov; 28(11):1040-2. doi: ". [PMID: 15615411]
  • W Z Liu, F L He, Z Y Ruan, X F Gu, X Y Wu, G W Qin. [Studies on chemical constituents from Euphorbia fischeriana Steud]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2001 Mar; 26(3):180-2. doi: ". [PMID: 12525037]
  • Y Gu, Y Tu. [Chemical constituents of Cirsium Japonicum D. C]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 1992 Aug; 17(8):489-90, 512. doi: ". [PMID: 1482537]
  • M He. [Studies on chemical constituents of the seeds of Forsythia suspensa I--isolation and identification of liposoluble components]. Zhong yao tong bao (Beijing, China : 1981). 1983 Mar; 8(2):34. doi: ". [PMID: 6222811]