Fluazinam (BioDeep_00000001757)

   

natural product


代谢物信息卡片


Pesticide4_Fluazinam_C13H4Cl2F6N4O4_2-Pyridinamine, 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-

化学式: C13H4Cl2F6N4O4 (463.9514)
中文名称: 甲醇中氟啶胺溶液
谱图信息: 最多检出来源 Mentha canadensis(plant) 28.95%

分子结构信息

SMILES: C1=C(C=NC(=C1Cl)NC2=C(C=C(C(=C2[N+](=O)[O-])Cl)C(F)(F)F)[N+](=O)[O-])C(F)(F)F
InChI: InChI=1S/C13H4Cl2F6N4O4/c14-6-1-4(12(16,17)18)3-22-11(6)23-9-7(24(26)27)2-5(13(19,20)21)8(15)10(9)25(28)29/h1-3H,(H,22,23)

描述信息

CONFIDENCE standard compound; EAWAG_UCHEM_ID 119

同义名列表

3 个代谢物同义名

Fluazinam; Pesticide4_Fluazinam_C13H4Cl2F6N4O4_2-Pyridinamine, 3-chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-; Fluazinam



数据库引用编号

24 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 12 AIMP2, ARHGAP45, BAX, BCL2, CASP3, CASP9, CAT, DNAJC7, GAPDH, HPGDS, LMLN, MAPK8
Peripheral membrane protein 1 CYP1B1
Endoplasmic reticulum membrane 4 BAX, BCL2, CYP1B1, UGT1A1
Nucleus 9 AIMP2, BAX, BCL2, CASP3, CASP9, DNAJC7, GAPDH, MAPK8, PARP1
cytosol 13 AIMP2, ARHGAP45, BAX, BCL2, CASP3, CASP9, CAT, DNAJC7, GAPDH, HPGDS, LMLN, MAPK8, PARP1
nuclear body 1 PARP1
nucleoplasm 7 ATP2B1, CASP3, CD2, DNAJC7, HPGDS, MAPK8, PARP1
Cell membrane 2 ATP2B1, CD2
ruffle membrane 1 ARHGAP45
Multi-pass membrane protein 2 ATP2B1, SYP
Synapse 2 ATP2B1, MAPK8
cell surface 1 CD2
glutamatergic synapse 2 ATP2B1, CASP3
Golgi apparatus 1 CD2
mitochondrial inner membrane 1 ATP5ME
neuromuscular junction 1 SYP
neuronal cell body 1 CASP3
presynaptic membrane 2 ATP2B1, SYP
synaptic vesicle 1 SYP
Cytoplasm, cytosol 3 AIMP2, GAPDH, PARP1
plasma membrane 5 ARHGAP45, ATP2B1, CD2, GAPDH, UGT1A1
presynaptic active zone 1 SYP
synaptic vesicle membrane 2 ATP2B1, SYP
terminal bouton 1 SYP
Membrane 13 AIMP2, ARHGAP45, ATP2B1, BAX, BCL2, CAT, CYP1B1, DNAJC7, GAPDH, LMLN, PARP1, SYP, UGT1A1
axon 1 MAPK8
basolateral plasma membrane 1 ATP2B1
extracellular exosome 6 ATP2B1, BAX, CAT, DNAJC7, GAPDH, SOD2
endoplasmic reticulum 3 BAX, BCL2, UGT1A1
perinuclear region of cytoplasm 3 GAPDH, SYP, UGT1A1
Schaffer collateral - CA1 synapse 1 SYP
mitochondrion 8 ATP5ME, BAX, BCL2, CASP9, CAT, CYP1B1, PARP1, SOD2
protein-containing complex 5 BCL2, CASP9, CAT, CD2, PARP1
intracellular membrane-bounded organelle 5 ATP2B1, CAT, CYP1B1, GAPDH, HPGDS
Microsome membrane 1 CYP1B1
postsynaptic density 1 CASP3
Single-pass type I membrane protein 1 CD2
extracellular region 3 ARHGAP45, CAT, CD2
cytoplasmic side of plasma membrane 1 CD2
Mitochondrion outer membrane 1 BCL2
Single-pass membrane protein 3 BAX, BCL2, UGT1A1
mitochondrial outer membrane 2 BAX, BCL2
excitatory synapse 1 SYP
Mitochondrion matrix 1 SOD2
mitochondrial matrix 2 CAT, SOD2
transcription regulator complex 1 PARP1
BAK complex 1 BAX
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 2 ATP2B1, SYP
Nucleus membrane 1 BCL2
Bcl-2 family protein complex 2 BAX, BCL2
nuclear membrane 2 BCL2, GAPDH
external side of plasma membrane 1 CD2
microtubule cytoskeleton 1 GAPDH
nucleolus 1 PARP1
cell-cell junction 1 CD2
vesicle 1 GAPDH
Cell projection, ruffle membrane 1 ARHGAP45
Cytoplasm, perinuclear region 2 GAPDH, UGT1A1
pore complex 2 BAX, BCL2
Cytoplasm, cytoskeleton 2 DNAJC7, GAPDH
focal adhesion 2 CAT, LMLN
mitochondrial nucleoid 1 SOD2
Peroxisome 1 CAT
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
lateral plasma membrane 1 ATP2B1
neuron projection 1 SYP
chromatin 1 PARP1
cell projection 1 ATP2B1
Chromosome 1 PARP1
cytoskeleton 2 DNAJC7, GAPDH
Nucleus, nucleolus 1 PARP1
nuclear replication fork 1 PARP1
chromosome, telomeric region 1 PARP1
Basolateral cell membrane 1 ATP2B1
site of double-strand break 1 PARP1
nuclear envelope 2 BAX, PARP1
Endomembrane system 1 SYP
Lipid droplet 2 GAPDH, LMLN
Presynaptic cell membrane 1 ATP2B1
myelin sheath 1 BCL2
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 2 ARHGAP45, CAT
azurophil granule lumen 1 ARHGAP45
immunological synapse 1 ATP2B1
apoptosome 1 CASP9
ribonucleoprotein complex 1 GAPDH
Synapse, synaptosome 1 SYP
protein-DNA complex 1 PARP1
basal dendrite 1 MAPK8
death-inducing signaling complex 1 CASP3
aminoacyl-tRNA synthetase multienzyme complex 1 AIMP2
GAIT complex 1 GAPDH
site of DNA damage 1 PARP1
proton-transporting ATP synthase complex 1 ATP5ME
proton-transporting ATP synthase complex, coupling factor F(o) 1 ATP5ME
catalase complex 1 CAT
mitochondrial permeability transition pore complex 1 BAX
endoplasmic reticulum chaperone complex 1 UGT1A1
[Poly [ADP-ribose] polymerase 1, processed N-terminus]: Chromosome 1 PARP1
[Poly [ADP-ribose] polymerase 1, processed C-terminus]: Cytoplasm 1 PARP1
BAD-BCL-2 complex 1 BCL2
photoreceptor ribbon synapse 1 ATP2B1
cytochrome complex 1 UGT1A1
caspase complex 1 CASP9
[Isoform Alpha]: Mitochondrion outer membrane 1 BAX
[Isoform Delta]: Cytoplasm 1 BAX
BAX complex 1 BAX


文献列表

  • Kun Fan, Yu-Kun Qi, Li Fu, Li Li, Xinghong Liu, Jianlu Qu, De-Wei Li, Ai-Xin Dong, Yi-Ji Peng, Qing-Hai Wang. Identification and fungicide screening of fungal species associated with walnut anthracnose in Shaanxi and Liaoning provinces, China. Plant disease. 2023 Sep; ?(?):. doi: 10.1094/pdis-05-23-0967-re. [PMID: 37682223]
  • Xiaohong Zhang, Gang Tang, Zhiyuan Zhou, Huachen Wang, Xuan Li, Guangyao Yan, Yulu Liu, Yuqi Huang, Jialu Wang, Yongsong Cao. Fabrication of Enzyme-Responsive Prodrug Self-Assembly Based on Fluazinam for Reducing Toxicity to Aquatic Organisms. Journal of agricultural and food chemistry. 2023 Aug; 71(34):12678-12687. doi: 10.1021/acs.jafc.3c03762. [PMID: 37595273]
  • Shazma Gulzar, Muhammad Aamir Manzoor, Fiza Liaquat, Muhammad Salman Zahid, Samiah Arif, Xuanwei Zhou, Yidong Zhang. Endophytic bacterial diversity by 16S rRNA gene sequencing of Pak choi roots under fluazinam, Trichoderma harzianum, and Sophora flavescens inoculation. Functional & integrative genomics. 2023 06; 23(2):194. doi: 10.1007/s10142-023-01119-8. [PMID: 37266724]
  • Li Chen, Fugen Li, ZhenTao Zhang, Junjie Jing, Ercheng Zhao, Pingzhong Yu, Min He, Yan Tao, Jingwei Zhang. Residues and dietary risk assessment of fluazinam in root mustard after field experiments. Environmental science and pollution research international. 2023 Mar; ?(?):. doi: 10.1007/s11356-023-26336-3. [PMID: 36929251]
  • Luoyu Wu, Zhiwen Wu, Feifei Zhao, Matthias Hahn, Mingguo Zhou, Yiping Hou. Activity and cell toxicology of fluazinam on Fusarium graminearum. Pesticide biochemistry and physiology. 2022 Nov; 188(?):105253. doi: 10.1016/j.pestbp.2022.105253. [PMID: 36464359]
  • Jhulia Gelain, Sydney Lykins, Pâmela Franciella Rosa, Alex Teixeira Soares, Madeline Elizabeth Dowling, Guido Schnabel, Louise Larissa May De Mio. Identification and Fungicide Sensitivity of Colletotrichum spp. from Apple Flowers and Fruitlets in Brazil. Plant disease. 2022 Oct; ?(?):. doi: 10.1094/pdis-01-22-0243-re. [PMID: 36256738]
  • Rogério F Vieira, Renan C Lima, Pablo H Teixeira, Trazilbo J Paula Júnior, José Eustáquio S Carneiro, Felipe Possamai, Heder Braun, Marilene S Lima. Managing White Mold on Common Bean with Type III Growth Habit by Integrating Partial Resistance, Plant Density, and Fungicide. Plant disease. 2022 Oct; 106(10):2672-2677. doi: 10.1094/pdis-11-21-2414-re. [PMID: 35224984]
  • Qizheng Liu, Panqing Liu, Yanjun Xu, Bin Wang, Pengfei Liu, Jianjun Hao, Xili Liu. Encapsulation of fluazinam to extend efficacy duration in controlling Botrytis cinerea on cucumber. Pest management science. 2021 Jun; 77(6):2836-2842. doi: 10.1002/ps.6318. [PMID: 33538400]
  • Tao Li, Qian Xiu, Jie Zhang, Jian Xin Wang, Ya Bing Duan, Ming Guo Zhou. Pharmacological Characteristics and Efficacy of Fluazinam Against Corynespora cassiicola, Causing Cucumber Target Spot in Greenhouses. Plant disease. 2020 Sep; 104(9):2449-2454. doi: 10.1094/pdis-12-19-2649-re. [PMID: 32579058]
  • Nabil A Younes, Mona F A Dawood, Ahmed A Wardany. The phyto-impact of fluazinam fungicide on cellular structure, agro-physiological, and yield traits of pepper and eggplant crops. Environmental science and pollution research international. 2020 May; 27(15):18064-18078. doi: 10.1007/s11356-020-08289-z. [PMID: 32170615]
  • Jian Hu, Yuxin Zhou, Tao Gao, Jiamei Geng, Yuan Dai, Haiyan Ren, Kurt Lamour, Xili Liu. Resistance risk assessment for fludioxonil in Sclerotinia homoeocarpa in China. Pesticide biochemistry and physiology. 2019 May; 156(?):123-128. doi: 10.1016/j.pestbp.2019.02.011. [PMID: 31027571]
  • Yi-Ping Hou, Xue-Wei Mao, Luo-Yu Wu, Jian-Xin Wang, Bao Mi, Ming-Guo Zhou. Impact of fluazinam on morphological and physiological characteristics of Sclerotinia sclerotiorum. Pesticide biochemistry and physiology. 2019 Mar; 155(?):81-89. doi: 10.1016/j.pestbp.2019.01.009. [PMID: 30857631]
  • Li Chen, Chunhong Jia, Fugen Li, Junjie Jing, Pingzhong Yu, Min He, Ercheng Zhao. Dissipation and residues of fluazinam and dimethomorph in potatoes, potato plants, and soil, determined by QuEChERS ultra-performance liquid chromatography tandem mass spectrometry. Environmental science and pollution research international. 2018 Nov; 25(32):32783-32790. doi: 10.1007/s11356-018-3281-7. [PMID: 30251039]
  • Xiang-Pu Qu, Jiao-Sheng Li, Jian-Xin Wang, Luo-Yu Wu, Ying-Fan Wang, Chang-Jun Chen, Ming-Guo Zhou, Yi-Ping Hou. Effects of the dinitroaniline fungicide fluazinam on Fusarium fujikuroi and rice. Pesticide biochemistry and physiology. 2018 Nov; 152(?):98-105. doi: 10.1016/j.pestbp.2018.09.010. [PMID: 30497718]
  • Guopeng Miao, Juan Han, Tao Ye, Zhina Chen, Kegui Zhang. Efficiency and Safety Assurance of Six Fungicides Applied on Postharvest Cabbages Stored in a Natural Environment. Journal of agricultural and food chemistry. 2018 Oct; 66(41):10864-10870. doi: 10.1021/acs.jafc.8b03910. [PMID: 30272962]
  • Yingying Song, Lili Li, Chao Li, Zengbin Lu, Xingyuan Men, Fajun Chen. Evaluating the Sensitivity and Efficacy of Fungicides with Different Modes of Action Against Botryosphaeria dothidea. Plant disease. 2018 Sep; 102(9):1785-1793. doi: 10.1094/pdis-01-18-0118-re. [PMID: 30125189]
  • Ya-Li Chen, Xue-Wei Mao, Jian-Xin Wang, Luo-Yu Wu, Ming-Guo Zhou, Yi-Ping Hou. Activity of the dinitroaniline fungicide fluazinam against Bipolaris maydis. Pesticide biochemistry and physiology. 2018 Jun; 148(?):8-15. doi: 10.1016/j.pestbp.2018.03.005. [PMID: 29891381]
  • Xue-Wei Mao, Jiao-Sheng Li, Ya-Li Chen, Xiu-Shi Song, Ya-Bing Duan, Jian-Xin Wang, Chang-Jun Chen, Ming-Guo Zhou, Yi-Ping Hou. Resistance risk assessment for fluazinam in Sclerotinia sclerotiorum. Pesticide biochemistry and physiology. 2018 Jan; 144(?):27-35. doi: 10.1016/j.pestbp.2017.10.010. [PMID: 29463405]
  • Biljana Mirković, Brankica Tanović, Jovana Hrustić, Milica Mihajlović, Milan Stević, Goran Delibašić, Petar Vukša. Toxicity of copper hydroxide, dithianon, fluazinam, tebuconazole and pyraclostrobin to Didymella applanata isolates from Serbia. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. 2015; 50(3):175-83. doi: 10.1080/03601234.2015.982414. [PMID: 25602150]
  • Wenyong Shao, Yu Zhang, Weichao Ren, Changjun Chen. Physiological and biochemical characteristics of laboratory induced mutants of Botrytis cinerea with resistance to fluazinam. Pesticide biochemistry and physiology. 2015 Jan; 117(?):19-23. doi: 10.1016/j.pestbp.2014.10.003. [PMID: 25619907]
  • D E Partridge-Telenko, J Hu, D M Livingstone, B B Shew, P M Phipps, E A Grabau. Sclerotinia blight resistance in Virginia-type peanut transformed with a barley oxalate oxidase gene. Phytopathology. 2011 Jul; 101(7):786-93. doi: 10.1094/phyto-10-10-0266. [PMID: 21303213]
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  • Mario Serrano, Silke Robatzek, Martha Torres, Erich Kombrink, Imre E Somssich, Mike Robinson, Paul Schulze-Lefert. Chemical interference of pathogen-associated molecular pattern-triggered immune responses in Arabidopsis reveals a potential role for fatty-acid synthase type II complex-derived lipid signals. The Journal of biological chemistry. 2007 Mar; 282(9):6803-11. doi: 10.1074/jbc.m608792200. [PMID: 17166839]
  • Gertie H P Arts, Laura L Buijse-Bogdan, J Dick M Belgers, Caroline H van Rhenen-Kersten, Rene P A van Wijngaarden, Ivo Roessink, Steve J Maund, Paul J van den Brink, Theo C M Brockt. Ecological impact in ditch mesocosms of simulated spray drift from a crop protection program for potatoes. Integrated environmental assessment and management. 2006 Apr; 2(2):105-25. doi: . [PMID: 16646380]
  • E B Cornel, R de Wit, J A Witjes. Evaluation of early pelvic floor physiotherapy on the duration and degree of urinary incontinence after radical retropubic prostatectomy in a non-teaching hospital. World journal of urology. 2005 Nov; 23(5):353-5. doi: 10.1007/s00345-005-0003-9. [PMID: 16211421]
  • Epaminondas J Paplomatas, Athanasios C Pappas, Elene Syranidou. Molecular characterization and biological response to respiration inhibitors of Pyricularia isolates from ctenanthe and rice plants. Pest management science. 2005 Jul; 61(7):691-8. doi: 10.1002/ps.1036. [PMID: 15739234]
  • L Hautier, J P Jansen, B Schiffers, R Deleu, C Moreira. Drawing-up of pesticide selectivity lists to beneficial arthropods for IPM programmes in potato. Communications in agricultural and applied biological sciences. 2004; 69(3):171-81. doi: ". [PMID: 15759409]
  • Shigeru Mitani, Koji Sugimoto, Hiroyuki Hayashi, Yasuko Takii, Takeshi Ohshima, Norifusa Matsuo. Effects of cyazofamid against Plasmodiophora brassicae Woronin on Chinese cabbage. Pest management science. 2003 Mar; 59(3):287-93. doi: 10.1002/ps.627. [PMID: 12639045]
  • A Draper, P Cullinan, C Campbell, M Jones, A Newman Taylor. Occupational asthma from fungicides fluazinam and chlorothalonil. Occupational and environmental medicine. 2003 Jan; 60(1):76-7. doi: 10.1136/oem.60.1.76. [PMID: 12499462]