2,3-Dihydroxypropyl dodecanoate (BioDeep_00000173508)
human metabolite blood metabolite
描述信息
D020011 - Protective Agents > D002327 - Cariostatic Agents
D001697 - Biomedical and Dental Materials
D013501 - Surface-Active Agents
同义名列表
36 个代谢物同义名
Dodecanoic acid, 2,3-dihydroxypropyl ester; Dodecanoate, 2,3-dihydroxypropyl ester; Dodecanoic acid alpha-monoglyceride; 2,3-Dihydroxypropyl dodecanoic acid; Dodecanoate alpha-monoglyceride; Dodecanoic acid a-monoglyceride; 2,3-Dihydroxypropyl dodecanoate; 2,3-Dihydroxypropyl lauric acid; Dodecanoic acid α-monoglyceride; 2,3-Dihydroxypropyl laic acid; rac-sn-1(3)-Dodecylglycerol; Dodecanoate α-monoglyceride; Lauric acid 1-monoglyceride; Dodecanoate a-monoglyceride; 2,3-Dihydroxypropyl laurate; Laic acid 1-monoglyceride; 2,3-Dihydroxypropyl laate; 1-Monododecanoylglycerol; Glyceryl monolauric acid; Glyceryl monolaic acid; Laate 1-monoglyceride; Glyceryl monolaurate; 1-Dodecanoylglycerol; Glycerol monolaurate; Monoglycerol laurate; 1-O-Dodecylglycerol; Monododecylglycerol; Glyceryl monolaate; 1-Dodecylglycerol; GLYCERYL LAURATE; UNII:WR963Y5QYW; 1-Monomyristin; 1-Monolaurin; Monolaurin; Lauricidin; Monolaurin
数据库引用编号
11 个数据库交叉引用编号
- ChEBI: CHEBI:75543
- ChEBI: CHEBI:75539
- PubChem: 14871
- HMDB: HMDB0245396
- ChEMBL: CHEMBL510533
- KNApSAcK: C00049928
- chemspider: 14181
- CAS: 27215-38-9
- CAS: 40738-26-9
- CAS: 67701-26-2
- CAS: 142-18-7
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Thomas Vennard, Nathan A Meredith, Sarah D Maria, Lauren Brink, Neil Shah, Ardythe L Morrow, Ruth Simmons, Michael A Gray, Shay C Phillips. A novel LC-MS/MS method to characterize the antimicrobial lipid glycerol monolaurate in global human milk.
Journal of pharmaceutical and biomedical analysis.
2023 Oct; 238(?):115817. doi:
10.1016/j.jpba.2023.115817. [PMID: 37939550] - Adam Yasgar, Danielle Bougie, Richard T Eastman, Ruili Huang, Misha Itkin, Jennifer Kouznetsova, Caitlin Lynch, Crystal McKnight, Mitch Miller, Deborah K Ngan, Tyler Peryea, Pranav Shah, Paul Shinn, Menghang Xia, Xin Xu, Alexey V Zakharov, Anton Simeonov. Quantitative Bioactivity Signatures of Dietary Supplements and Natural Products.
ACS pharmacology & translational science.
2023 May; 6(5):683-701. doi:
10.1021/acsptsci.2c00194. [PMID: 37200814] - Huanhuan Cui, Cuie Tang, Shan Wu, David Julian McClements, Shilin Liu, Bin Li, Yan Li. Fabrication of chitosan-cinnamaldehyde-glycerol monolaurate bigels with dual gelling effects and application as cream analogs.
Food chemistry.
2022 Aug; 384(?):132589. doi:
10.1016/j.foodchem.2022.132589. [PMID: 35258001] - Longxian Li, Huakai Wang, Nan Zhang, Tuan Zhang, Yongxi Ma. Effects of α-glycerol monolaurate on intestinal morphology, nutrient digestibility, serum profiles, and gut microbiota in weaned piglets.
Journal of animal science.
2022 Mar; 100(3):. doi:
10.1093/jas/skac046. [PMID: 35167667] - Jing Wang, Huiqi Jiang, Yasmin Alhamoud, Yong Chen, Jiachen Zhuang, Tao Liu, Luyun Cai, Weiliang Shen, Xiongfei Wu, Weiqiang Zheng, Fengqin Feng. Integrated metabolomic and gene expression analyses to study the effects of glycerol monolaurate on flesh quality in large yellow croaker (Larimichthys crocea).
Food chemistry.
2022 Jan; 367(?):130749. doi:
10.1016/j.foodchem.2021.130749. [PMID: 34375886] - Maha Raafat Abd El Fadeel, Eman M Soliman, Ahmad Mohammad Allam, Mohamed F ElKersh, Rehab Mahmoud Abd El-Baky, Ahmad Mustafa. Efficacy and durability of bovine virus diarrhea (BVD) virus killed vaccine adjuvanted with monolaurin.
PloS one.
2022; 17(7):e0269031. doi:
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International journal of molecular sciences.
2021 Dec; 23(1):. doi:
10.3390/ijms23010384. [PMID: 35008810] - Sini Kang, Yaqing Guo, Junhui Rao, Hui Jin, Hyun Ju You, Geun Eog Ji. In vitro and in vivo inhibition of Helicobacter pylori by Lactobacillus plantarum pH3A, monolaurin, and grapefruit seed extract.
Food & function.
2021 Nov; 12(21):11024-11032. doi:
10.1039/d1fo01480c. [PMID: 34657941] - Linglian Kong, Zhenhua Wang, Chuanpi Xiao, Qidong Zhu, Zhigang Song. Glycerol Monolaurate Ameliorated Intestinal Barrier and Immunity in Broilers by Regulating Intestinal Inflammation, Antioxidant Balance, and Intestinal Microbiota.
Frontiers in immunology.
2021; 12(?):713485. doi:
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Anais da Academia Brasileira de Ciencias.
2021; 93(suppl 4):e20210687. doi:
10.1590/0001-3765202120210687. [PMID: 34909829] - Tao Liu, Jun Tang, Fengqin Feng. Glycerol monolaurate improves performance, intestinal development, and muscle amino acids in yellow-feathered broilers via manipulating gut microbiota.
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2020 Nov; 13(1):527. doi:
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Nutrients.
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International journal of pharmaceutics.
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Microbial pathogenesis.
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2019 03; 35(9):3568-3575. doi:
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Antimicrobial agents and chemotherapy.
1994 Jul; 38(7):1523-9. doi:
10.1128/aac.38.7.1523. [PMID: 7979283] - N Yamamoto, N P Willett, D D Lindsay. Participation of serum proteins in the inflammation-primed activation of macrophages.
Inflammation.
1994 Jun; 18(3):311-22. doi:
10.1007/bf01534272. [PMID: 8088927] - N Yamamoto, R Kumashiro. Conversion of vitamin D3 binding protein (group-specific component) to a macrophage activating factor by the stepwise action of beta-galactosidase of B cells and sialidase of T cells.
Journal of immunology (Baltimore, Md. : 1950).
1993 Sep; 151(5):2794-802. doi:
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European journal of cancer (Oxford, England : 1990).
1992; 28A(10):1637-42. doi:
10.1016/0959-8049(92)90058-a. [PMID: 1389479] - N Yamamoto, S Homma, J G Haddad, M A Kowalski. Vitamin D3 binding protein required for in vitro activation of macrophages after alkylglycerol treatment of mouse peritoneal cells.
Immunology.
1991 Nov; 74(3):420-4. doi:
NULL. [PMID: 1769691] - H S Ved, E Gustow, R A Pieringer. Regulation of neuronal differentiation in neuron-enriched primary cultures from embryonic rat cerebra by platelet activating factor and the structurally related glycerol ether lipid, dodecylglycerol.
Journal of neuroscience research.
1991 Oct; 30(2):353-8. doi:
10.1002/jnr.490300211. [PMID: 1798056] - B Z Ngwenya, D M Foster. Enhancement of antibody production by lysophosphatidylcholine and alkylglycerol.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.).
1991 Jan; 196(1):69-75. doi:
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Immunology and cell biology.
1990 Apr; 68 ( Pt 2)(?):137-42. doi:
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Clinical and experimental immunology.
1990 Feb; 79(2):307-13. doi:
10.1111/j.1365-2249.1990.tb05195.x. [PMID: 2178824] - H S Ved, E Gustow, R A Pieringer. Synergism between penicillin G and the antimicrobial ether lipid, rac-1-dodecylglycerol, acting below its critical micelle concentration.
Lipids.
1990 Feb; 25(2):119-21. doi:
10.1007/bf02562216. [PMID: 2329923] - E A Cabacungan, E Gustow, R A Pieringer. In vivo studies on stereospecificity of the monoglyceride kinase, lysophosphatidic acid acyltransferase, phosphatidic acid phosphatase and CDP-diglyceride synthase of Streptococcus mutans BHT using the stereoisomers of the ether lipid, dodecylglycerol.
Biochimica et biophysica acta.
1988 Sep; 962(2):241-7. doi:
10.1016/0005-2760(88)90166-x. [PMID: 2844276] - J L Brissette, E A Cabacungan, R A Pieringer. Studies on the antibacterial activity of dodecylglycerol. Its limited metabolism and inhibition of glycerolipid and lipoteichoic acid biosynthesis in Streptococcus mutans BHT.
The Journal of biological chemistry.
1986 May; 261(14):6338-45. doi:
10.1016/s0021-9258(19)84568-4. [PMID: 3634775] - N Weber. Metabolism of orally administered rac-1-O-[1'-14C]dodecylglycerol and nutritional effects of dietary rac-1-O-dodecylglycerol in mice.
Journal of lipid research.
1985 Dec; 26(12):1412-20. doi:
NULL. [PMID: 4086944]
