Alizarin (BioDeep_00000017252)

 

Secondary id: BioDeep_00000000174, BioDeep_00000406110

human metabolite PANOMIX_OTCML-2023 blood metabolite


代谢物信息卡片


InChI=1/C14H8O4/c15-10-6-5-9-11(14(10)18)13(17)8-4-2-1-3-7(8)12(9)16/h1-6,15,18

化学式: C14H8O4 (240.0422568)
中文名称: 茜素
谱图信息: 最多检出来源 Viridiplantae(plant) 0.86%

分子结构信息

SMILES: C1=CC=C2C(=C1)C(=O)C3=C(C2=O)C(=C(C=C3)O)O
InChI: InChI=1S/C14H8O4/c15-10-6-5-9-11(14(10)18)13(17)8-4-2-1-3-7(8)12(9)16/h1-6,15,18H

描述信息

Alizarin is a dihydroxyanthraquinone that is anthracene-9,10-dione in which the two hydroxy groups are located at positions 1 and 2. It has a role as a chromophore, a dye and a plant metabolite.
Alizarin is a natural product found in Oldenlandia umbellata, Rubia alata, and other organisms with data available.
See also: Rubia tinctorum root (part of).
A dihydroxyanthraquinone that is anthracene-9,10-dione in which the two hydroxy groups are located at positions 1 and 2.
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同义名列表

91 个代谢物同义名

InChI=1/C14H8O4/c15-10-6-5-9-11(14(10)18)13(17)8-4-2-1-3-7(8)12(9)16/h1-6,15,18; 1,2-dihydroxy-9,10-dihydroanthracene-9,10-dione; 4-08-00-03256 (Beilstein Handbook Reference); 1,2-bis(oxidanyl)anthracene-9,10-dione; 9,10-Anthracenedione, 1,2-dihydroxy-; ?1,2-Dihydroxy-9,10-anthracenedione; 1,2-Dihydroxy-9,10-anthracenedione; 1,2-Dihydroxyanthra-9,10-quinone #; 1,2-dihydroxyanthracene-9,10-dione; 1,2-Dihydroxyanthrachinon [Czech]; Alizarine Paste 20 percent Bluish; 1,10-dihydroxy-2,9-anthraquinone; 9,10-dihydroxy-1,2-anthraquinone; 1,2-Dihydroxyanthra-9,10-quinone; 1,2-Dihydroxy-9,10-anthraquinone; 2,9-dihydroxy-1,10-anthraquinone; DIHYDROXY-9,10-ANTHRACENEDIONE; Anthraquinone, 1,2-dihydroxy-; D&C ORANGE NO. 15 (DELISTED); 1,2-Dihydroxy anthraquinone; 1,2-Dihydroxy-anthraquinone; Alizarin, Dye content 97 \\%; Alizarine paste 20\\% bluish; 1,2-dihydroxyanthraquinone; D and C Orange Number 15D; 1,2-Dihydroxyanthrachinon; D And C Orange Number 15; Alizarine Lake Red IPX; Alizarine Lake Red 2P; 1,2-Anthraquinonediol; Alizarinprimeveroside; Alizarine Lake Red 3P; D and C Orange No. 15; Certiqual Alizarine D; C.I. Mordant Red 11C; Certiqual Alizarine; Mitsui Alizarine BS; C.I. Mordant Red 11; Alizarine indicator; Sanyo Carmine l2BT; Mitsui Alizarine B; Alizarine Red IPP; Alizarine L paste; 9, 1,2-dihydroxy-; Sanyo Carmine L2B; Alizerine Red IPP; Spectrum5_000150; Spectrum4_001555; Alizarine Red B2; Spectrum3_000262; Turkey Red (VAN); Spectrum2_000397; Alizarine Red IP; ATHRAQUINONES A; Alizarine Red L; UNII-60MEW57T9G; Alizarine Red B; Tox21_111486_1; Mordant Red 11; Anthraquinonic; Alizarin, p.a.; Eljon Madder M; ALIZARIN [MI]; Alizarine Red; 1,2-Dihydroxy; Alizerine NAC; DivK1c_006416; Alizarine NAC; KBio2_003434; KBio1_001360; Alizarine 3B; KBio2_000866; Turkey Red W; KBio2_006002; Tox21_111486; alizarin red; NCI60_041501; KBio3_001204; Eljon Madder; Alizarine B; CAS-72-48-0; Hystazarin; Alizarin B; Turkey Red; 60MEW57T9G; Alizarina; Pincoffin; alizarine; AI3-18244; Alizarin; Az



数据库引用编号

18 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

36 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Zhongjing Jiang, Linhua Deng, Mengjun Li, Emmanuel Alonge, Yanling Wang, Yunjia Wang. Ginsenoside Rg1 modulates PI3K/AKT pathway for enhanced osteogenesis via GPER. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Feb; 124(?):155284. doi: 10.1016/j.phymed.2023.155284. [PMID: 38176267]
  • Wei Xiong, Lingmei Yuan, Liangxia Wang, Guowen Qian, Chaoyi Liang, Bin Pan, Ling Guo, Wenqiang Wei, Xunxiang Qiu, Wenfang Deng, Zhikui Zeng. [Preparation of berberine-naringin dual drug-loaded composite microspheres and evaluation of their antibacterial-osteogenic properties]. Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery. 2023 Dec; 37(12):1505-1513. doi: 10.7507/1002-1892.202308054. [PMID: 38130195]
  • Hongpeng Yu, Qing Zhou, Dong He, JinJin Yang, Kegang Wu, Xianghua Chai, Yujuan Xiang, Xuejuan Duan, Xiqin Wu. Enhanced mechanical and functional properties of chitosan/polyvinyl alcohol/hydroxypropyl methylcellulose/alizarin composite film by incorporating cinnamon essential oil and tea polyphenols. International journal of biological macromolecules. 2023 Sep; ?(?):126859. doi: 10.1016/j.ijbiomac.2023.126859. [PMID: 37714243]
  • Xiaodan Zheng, Jingqiu Chen, Nanquan Rao, Chun Yang, Juan Liu, Jun Zhang, Yanhong Li. The Effect of an Extract of Sappanwood, Protosappanin A and Protosappanin B on Osteogenesis in Periodontitis. Frontiers in bioscience (Landmark edition). 2023 08; 28(8):172. doi: 10.31083/j.fbl2808172. [PMID: 37664926]
  • Zhenhua Ni, Honghong Ma, Xiaodong Li, Liwei Zou, Zongjun Liu, Xiongbiao Wang, Hong Ma, Ling Yang. Wogonin alleviates BaP-induced DNA damage and oxidative stress in human airway epithelial cells by dual inhibiting CYP1A1 activity and expression. Environmental toxicology. 2023 Jul; ?(?):. doi: 10.1002/tox.23907. [PMID: 37515497]
  • Lin Jin, Jiali Shan, Yanhong Hao, Yingchun Wang, Liping Liu. Enhanced bone regeneration by low-intensity pulsed ultrasound and lipid microbubbles on PLGA/TCP 3D-printed scaffolds. BMC biotechnology. 2023 06; 23(1):13. doi: 10.1186/s12896-023-00783-9. [PMID: 37280578]
  • Yuexuan Li, Jiaxing Zhang, Chengyu Zhang, Weifan Dang, Lu Xue, Hongliang Liu, Huiying Cheng, Xiaohui Yan. Facile and selective separation of anthraquinones by alizarin-modified iron oxide magnetic nanoparticles. Journal of chromatography. A. 2023 May; 1702(?):464088. doi: 10.1016/j.chroma.2023.464088. [PMID: 37230053]
  • Mengyuan Li, Yumeng Wang, Jing Xue, Qingqing Xu, Yuerong Zhang, Jie Liu, Hai Xu, Zhuo Guan, Chengyue Bian, Guangdong Zhang, Yan Yu. Baicalin can enhance odonto/osteogenic differentiation of inflammatory dental pulp stem cells by inhibiting the NF-κB and β-catenin/Wnt signaling pathways. Molecular biology reports. 2023 Apr; ?(?):. doi: 10.1007/s11033-023-08398-1. [PMID: 37009956]
  • Guan-Jun Yang, Fan Tao, Hai-Jing Zhong, Chao Yang, Jiong Chen. Targeting PGAM1 in cancer: An emerging therapeutic opportunity. European journal of medicinal chemistry. 2022 Dec; 244(?):114798. doi: 10.1016/j.ejmech.2022.114798. [PMID: 36215859]
  • Zihang Xu, Yifei Hou, Chunpu Zou, Haibin Liang, Jiasheng Mu, Xiaoning Jiao, Yangzhuangzhuang Zhu, Lin Su, Mingxi Liu, Xiao Chen, Chunmei Qian, Xiandan Zhu, Wei Gong, Qian Dong, Fei Zhang. Alizarin, a nature compound, inhibits the growth of pancreatic cancer cells by abrogating NF-κB activation. International journal of biological sciences. 2022; 18(7):2759-2774. doi: 10.7150/ijbs.70567. [PMID: 35541911]
  • Swarup Roy, Jong-Whan Rhim. Fabrication of Carboxymethyl Cellulose/Agar-Based Functional Films Hybridized with Alizarin and Grapefruit Seed Extract. ACS applied bio materials. 2021 05; 4(5):4470-4478. doi: 10.1021/acsabm.1c00214. [PMID: 35006859]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Marcela B Queiroz, Fernanda F E Torres, Elisandra M Rodrigues, Kennia S Viola, Roberta Bosso-Martelo, Gisselle M Chavez-Andrade, Marina T Souza, Edgar D Zanotto, Juliane M Guerreiro-Tanomaru, Mario Tanomaru-Filho. Development and evaluation of reparative tricalcium silicate-ZrO2 -Biosilicate composites. Journal of biomedical materials research. Part B, Applied biomaterials. 2021 04; 109(4):468-476. doi: 10.1002/jbm.b.34714. [PMID: 32860327]
  • Yipeng Sun, Zhaowen Shi, Yuhua Lin, Mengzhe Zhang, Jinjin Liu, Linyun Zhu, Qingge Chen, Junjie Bi, Shanqun Li, Zhenhua Ni, Xiongbiao Wang. Benzo(a)pyrene induces MUC5AC expression through the AhR/mitochondrial ROS/ERK pathway in airway epithelial cells. Ecotoxicology and environmental safety. 2021 Mar; 210(?):111857. doi: 10.1016/j.ecoenv.2020.111857. [PMID: 33421718]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Juan Qiao, Qianrong Liu, Han Wu, Huiwu Cai, Li Qi. Non-enzymatic detection of serum glucose using a fluorescent nanopolymer probe. Mikrochimica acta. 2019 05; 186(6):366. doi: 10.1007/s00604-019-3475-9. [PMID: 31114937]
  • Lanting Xu, Meimei Xing, Xiaoqing Xu, Fatma Sa Saadeldeen, Zhenhua Liu, Jinfeng Wei, Wenyi Kang. Alizarin increase glucose uptake through PI3K/Akt signaling and improve alloxan-induced diabetic mice. Future medicinal chemistry. 2019 03; 11(5):395-406. doi: 10.4155/fmc-2018-0515. [PMID: 30650995]
  • Sisubalan Natarajan, Priyanka Mishra, Malayaman Vadivel, M Ghouse Basha, Amit Kumar, Sundaresan Velusamy. ISSR Characterization and Quantification of Purpurin and Alizarin in Rubia cordifolia L. Populations from India. Biochemical genetics. 2019 Feb; 57(1):56-72. doi: 10.1007/s10528-018-9875-4. [PMID: 30039443]
  • Carmel Fargason, Nan Zhang, Mandi J Lopez. Feline Adult Adipose Tissue-Derived Multipotent Stromal Cell Isolation and Differentiation. Methods in molecular biology (Clifton, N.J.). 2018; 1773(?):173-188. doi: 10.1007/978-1-4939-7799-4_15. [PMID: 29687390]
  • Zuoliang Zheng, Shengqing Li, Yuping Zhong, Ruoting Zhan, Yan Yan, Huafeng Pan, Ping Yan. UPLC-QTOF-MS Identification of the Chemical Constituents in Rat Plasma and Urine after Oral Administration of Rubia cordifolia L. Extract. Molecules (Basel, Switzerland). 2017 Aug; 22(8):. doi: 10.3390/molecules22081327. [PMID: 28800124]
  • Jia Tang, Takashi Saito. Human plasma fibronectin promotes proliferation and differentiation of odontoblast. Journal of applied oral science : revista FOB. 2017 May; 25(3):299-309. doi: 10.1590/1678-7757-2016-0442. [PMID: 28678949]
  • M R Gandhi, A D Reegan, P Ganesan, K Sivasankaran, M G Paulraj, K Balakrishna, S Ignacimuthu, N A Al-Dhabi. Larvicidal and Pupicidal Activities of Alizarin Isolated from Roots of Rubia cordifolia Against Culex quinquefasciatus Say and Aedes aegypti (L.) (Diptera: Culicidae). Neotropical entomology. 2016 Aug; 45(4):441-8. doi: 10.1007/s13744-016-0386-x. [PMID: 27004695]
  • Satin Salehi, Paul Cooper, Anthony Smith, Jack Ferracane. Dentin matrix components extracted with phosphoric acid enhance cell proliferation and mineralization. Dental materials : official publication of the Academy of Dental Materials. 2016 Mar; 32(3):334-42. doi: 10.1016/j.dental.2015.11.004. [PMID: 26777093]
  • Abraham Daniel Arulraj, Muthunanthevar Vijayan, Vairathevar Sivasamy Vasantha. Spectrophotometric determination of pico-molar level of hydrazine by using Alizarin red in water and urine samples. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2015 Sep; 148(?):355-61. doi: 10.1016/j.saa.2015.03.092. [PMID: 25911160]
  • Lauren Ford, Christopher M Rayner, Richard S Blackburn. Isolation and extraction of ruberythric acid from Rubia tinctorum L. and crystal structure elucidation. Phytochemistry. 2015 Sep; 117(?):168-173. doi: 10.1016/j.phytochem.2015.06.015. [PMID: 26091962]
  • Hong-shuai Yang, Ju Wang, Cui Guo, Wei Liu, Yuan-yuan Chen, Jin-feng Wei, Wen-yi Kang. Simultaneous determination of alizarin and rubimaillin in Rubia cordifolia by ultrasound-assisted ionic liquid-reversed phase liquid chromatography. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2015 Jul; 40(13):2617-23. doi: ". [PMID: 26697688]
  • Vijaykumar L Dhadge, Abid Hussain, Ana M Azevedo, Raquel Aires-Barros, Ana C A Roque. Boronic acid-modified magnetic materials for antibody purification. Journal of the Royal Society, Interface. 2014 Feb; 11(91):20130875. doi: 10.1098/rsif.2013.0875. [PMID: 24258155]
  • Dariusz Toczek, Karolina Kubas, Michał Turek, Szczepan Roszak, Roman Gancarz. Theoretical studies of structure, energetics and properties of Ca²⁺ complexes with alizarin glucoside. Journal of molecular modeling. 2013 Oct; 19(10):4209-14. doi: 10.1007/s00894-013-1841-9. [PMID: 23605140]
  • Mingming Zou, Ying Li, Jun Wang, Jingqun Gao, Qi Wang, Baoxin Wang, Ping Fan. Spectroscopic studies on H2O2 damaging BSA induced by 1,2-dihydroxy-9, 10-anthraquinone-3-aminomethyl-N, N-diacetate-ferrous(III). Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2013 Aug; 112(?):206-13. doi: 10.1016/j.saa.2013.04.005. [PMID: 23666356]
  • N T Abdel-Ghani, M S Rizk, M Mostafa. Extractive determination of ephedrine hydrochloride and bromhexine hydrochloride in pure solutions, pharmaceutical dosage form and urine samples. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2013 Jul; 111(?):131-41. doi: 10.1016/j.saa.2013.03.038. [PMID: 23624039]
  • Farid A Badria, Ahmed S Ibrahim. Evaluation of natural anthracene-derived compounds as antimitotic agents. Drug discoveries & therapeutics. 2013 Apr; 7(2):84-9. doi: . [PMID: 23715507]
  • Thilo Christopher Fischer, Christian Gosch, Beate Mirbeth, Markus Gselmann, Veronika Thallmair, Karl Stich. Potent and specific bactericidal effect of juglone (5-hydroxy-1,4-naphthoquinone) on the fire blight pathogen Erwinia amylovora. Journal of agricultural and food chemistry. 2012 Dec; 60(49):12074-81. doi: 10.1021/jf303584r. [PMID: 23163769]
  • Natasha Baker, Guofeng Zhang, Yang You, Rocky S Tuan. Caveolin-1 regulates proliferation and osteogenic differentiation of human mesenchymal stem cells. Journal of cellular biochemistry. 2012 Dec; 113(12):3773-87. doi: 10.1002/jcb.24252. [PMID: 22807396]
  • Li Hong Zhang, Zhi Yong Zheng, Shu-Lian Jiang, Ma-Lin Cui, Li Jiao, Xuan Lin, Wen-Lian Cai, Shao-Qin Lin, Jia-Ming Liu. Coupling technique of self-ordered ring and phosphorimetry for the determination of alkaline phosphatase and diseases prediction. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2012 Nov; 97(?):639-47. doi: 10.1016/j.saa.2012.07.003. [PMID: 22858611]
  • Zhanguang Chen, Zhen Wang, Junhui Chen, Xi Chen. Alizarin red S/copper ion-based ensemble for fluorescence turn on detection of glutathione with tunable dynamic range. Biosensors & bioelectronics. 2012 Oct; 38(1):202-8. doi: 10.1016/j.bios.2012.05.030. [PMID: 22732668]
  • Swati Srivastava, Upasana Bedi, Partha Roy. Synergistic actions of insulin-sensitive and Sirt1-mediated pathways in the differentiation of mouse embryonic stem cells to osteoblast. Molecular and cellular endocrinology. 2012 Sep; 361(1-2):153-64. doi: 10.1016/j.mce.2012.04.002. [PMID: 22542761]
  • Fei Yi, Muhammad Khan, Hongwen Gao, Feng Hao, Meiyan Sun, Lili Zhong, Changzheng Lu, Xuechao Feng, Tonghui Ma. Increased differentiation capacity of bone marrow-derived mesenchymal stem cells in aquaporin-5 deficiency. Stem cells and development. 2012 Sep; 21(13):2495-507. doi: 10.1089/scd.2011.0597. [PMID: 22420587]
  • Michael Wolf, Stefan Lossdörfer, Nuersailike Abuduwali, Rainer Meyer, Sied Kebir, Werner Götz, Andreas Jäger. Effect of intermittent PTH(1-34) on human periodontal ligament cells transplanted into immunocompromised mice. Tissue engineering. Part A. 2012 Sep; 18(17-18):1849-56. doi: 10.1089/ten.tea.2011.0626. [PMID: 22497226]
  • Fang Liu, Ping Fu, Wenxing Fan, Rong Gou, Youqun Huang, Hongyu Qiu, Hui Zhong, Songmin Huang. Involvement of parathyroid hormone-related protein in vascular calcification of chronic haemodialysis patients. Nephrology (Carlton, Vic.). 2012 Aug; 17(6):552-60. doi: 10.1111/j.1440-1797.2012.01601.x. [PMID: 22448974]
  • Saeedeh Darzi, Amir Hassan Zarnani, Mahmood Jeddi-Tehrani, Kobra Entezami, Ebrahim Mirzadegan, Mohamad Mehdi Akhondi, Saeed Talebi, Manijeh Khanmohammadi, Somaieh Kazemnejad. Osteogenic differentiation of stem cells derived from menstrual blood versus bone marrow in the presence of human platelet releasate. Tissue engineering. Part A. 2012 Aug; 18(15-16):1720-8. doi: 10.1089/ten.tea.2011.0386. [PMID: 22571521]
  • Yu Ren, Haiqing Wu, Xueyuan Zhou, Jianxun Wen, Muzi Jin, Ming Cang, Xudong Guo, Qinglian Wang, Dongjun Liu, Yuzhen Ma. Isolation, expansion, and differentiation of goat adipose-derived stem cells. Research in veterinary science. 2012 Aug; 93(1):404-11. doi: 10.1016/j.rvsc.2011.08.014. [PMID: 21945802]
  • Hong-guang Xu, Xiao-hai Zhang, Hong Wang, Ping Liu, Ling-ting Wang, Chi-jian Zuo, Wen-xue Tong, Xiao-ling Zhang. Intermittent Cyclic Mechanical Tension-Induced Calcification and downregulation of ankh gene expression of end plate chondrocytes. Spine. 2012 Jun; 37(14):1192-7. doi: 10.1097/brs.0b013e318244d989. [PMID: 22695244]
  • Haiqing Wu, Yu Ren, Shuo Li, Wei Wang, Jianlong Yuan, Xudong Guo, Dongjun Liu, Ming Cang. In vitro culture and induced differentiation of sheep skeletal muscle satellite cells. Cell biology international. 2012 Jun; 36(6):579-87. doi: 10.1042/cbi20110487. [PMID: 22233500]
  • Eun Mi Choi. Magnolol protects osteoblastic MC3T3-E1 cells against antimycin A-induced cytotoxicity through activation of mitochondrial function. Inflammation. 2012 Jun; 35(3):1204-12. doi: 10.1007/s10753-012-9430-0. [PMID: 22281543]
  • Kunga Mohan Ramkumar, Chinnasamy Manjula, Georgepeter Gnanakumar, Muzafar A Kanjwal, Thillai V Sekar, Ramasamy Paulmurugan, Palanisamy Rajaguru. Oxidative stress-mediated cytotoxicity and apoptosis induction by TiO2 nanofibers in HeLa cells. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 2012 Jun; 81(2):324-33. doi: 10.1016/j.ejpb.2012.02.013. [PMID: 22446064]
  • Eleonora Iacono, Marco Cunto, Daniele Zambelli, Francesca Ricci, Pier Luigi Tazzari, Barbara Merlo. Could fetal fluid and membranes be an alternative source for mesenchymal stem cells (MSCs) in the feline species? A preliminary study. Veterinary research communications. 2012 Jun; 36(2):107-18. doi: 10.1007/s11259-012-9520-3. [PMID: 22327440]
  • An-ju Zhao, Song-min Huang, San-tao Ou, Fang Liu, Ze-jun Chen, Zhang-xue Hu, Wan-xin Tang. [Relation between bone matrix proteins and monocyte chemoattractant protein-1 in renal small artery in diabetic nephropathy rats]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition. 2012 May; 43(3):414-9. doi: NULL. [PMID: 22812249]
  • Xiao-Feng Zhu, Ting-Chun Wang, Rong-Hua Zhang. [Effects of yigu capsule containing serum on the osteoblast differentiation and the expressions of osteoprotegerin and bone morphogenetic protein 2 after treatment by advanced glycation end products in vitro]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine. 2012 Apr; 32(4):525-9. doi: . [PMID: 22803437]
  • Eleonora Iacono, Lara Brunori, Alessandro Pirrone, Pasquale Paolo Pagliaro, Francesca Ricci, Pier Luigi Tazzari, Barbara Merlo. Isolation, characterization and differentiation of mesenchymal stem cells from amniotic fluid, umbilical cord blood and Wharton's jelly in the horse. Reproduction (Cambridge, England). 2012 Apr; 143(4):455-68. doi: 10.1530/rep-10-0408. [PMID: 22274885]
  • Fei Tan, Feidhlim O'Neill, Mariam Naciri, Denis Dowling, Mohamed Al-Rubeai. Cellular and transcriptomic analysis of human mesenchymal stem cell response to plasma-activated hydroxyapatite coating. Acta biomaterialia. 2012 Apr; 8(4):1627-38. doi: 10.1016/j.actbio.2011.12.014. [PMID: 22202907]
  • Deliang Zeng, Lunguo Xia, Wenjie Zhang, Hui Huang, Bin Wei, Qingfeng Huang, Jie Wei, Changsheng Liu, Xinquan Jiang. Maxillary sinus floor elevation using a tissue-engineered bone with calcium-magnesium phosphate cement and bone marrow stromal cells in rabbits. Tissue engineering. Part A. 2012 Apr; 18(7-8):870-81. doi: 10.1089/ten.tea.2011.0379. [PMID: 22066969]
  • Malihezaman Monsefi, Fatemeh Parvin, Tahereh Talaei-Khozani. Effects of pomegranate extracts on cartilage, bone and mesenchymal cells of mouse fetuses. The British journal of nutrition. 2012 Mar; 107(5):683-90. doi: 10.1017/s0007114511003394. [PMID: 21781378]
  • Takayuki Suzuki, Koji Uetsuka, Kunio Doi, Tetsuo Nunoya. A case of renal oxalosis in a 3-month-old cat raised under controlled conditions. The Journal of veterinary medical science. 2012 Mar; 74(3):381-4. doi: 10.1292/jvms.11-0399. [PMID: 22067080]
  • Nesrine Ben Azouna, Faouzi Jenhani, Zohra Regaya, Lamia Berraeis, Tarek Ben Othman, Elfi Ducrocq, Jorge Domenech. Phenotypical and functional characteristics of mesenchymal stem cells from bone marrow: comparison of culture using different media supplemented with human platelet lysate or fetal bovine serum. Stem cell research & therapy. 2012 Feb; 3(1):6. doi: 10.1186/scrt97. [PMID: 22333342]
  • Natália Mencacci Esteves-Pedro, Thaisa Borim, Virginia Sbrugnera Nazato, Magali Glauzer Silva, Patricia Santos Lopes, Márcio Galdino dos Santos, Cháriston André Dal Belo, Cássia Regina Primila Cardoso, Eliana Aparecida Varanda, Francisco Carlos Groppo, Marli Gerenutti, Yoko Oshima-Franco. In vitro and in vivo safety evaluation of Dipteryx alata Vogel extract. BMC complementary and alternative medicine. 2012 Feb; 12(?):9. doi: 10.1186/1472-6882-12-9. [PMID: 22305153]
  • Fatih Kircelli, Mirjam E Peter, Ebru Sevinc Ok, Fatma Gul Celenk, Mumtaz Yilmaz, Sonja Steppan, Gulay Asci, Ercan Ok, Jutta Passlick-Deetjen. Magnesium reduces calcification in bovine vascular smooth muscle cells in a dose-dependent manner. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 2012 Feb; 27(2):514-21. doi: 10.1093/ndt/gfr321. [PMID: 21750166]
  • Jing Liu, Kun Ling Ma, Min Gao, Chang Xian Wang, Jie Ni, Yang Zhang, Xiao Liang Zhang, Hong Liu, Yan Li Wang, Bi Cheng Liu. Inflammation disrupts the LDL receptor pathway and accelerates the progression of vascular calcification in ESRD patients. PloS one. 2012; 7(10):e47217. doi: 10.1371/journal.pone.0047217. [PMID: 23115640]
  • Anton G Kutikhin, Elena B Brusina, Arseniy E Yuzhalin. The role of calcifying nanoparticles in biology and medicine. International journal of nanomedicine. 2012; 7(?):339-50. doi: 10.2147/ijn.s28069. [PMID: 22287843]
  • ChenChen Wu, XiaoBing Li, TieSuo Han, Peng Li, JianGuo Wang, GuoWen Liu, Zhe Wang, ChangRong Ge, ShiZheng Gao. Dietary pseudopurpurin improves bone geometry architecture and metabolism in red-bone Guishan goats. PloS one. 2012; 7(5):e37469. doi: 10.1371/journal.pone.0037469. [PMID: 22624037]
  • Guoyan Liang, Wenjie Gao, Anjing Liang, Wei Ye, Yan Peng, Liangming Zhang, Swarkar Sharma, Peiqiang Su, Dongsheng Huang. Normal leptin expression, lower adipogenic ability, decreased leptin receptor and hyposensitivity to Leptin in Adolescent Idiopathic Scoliosis. PloS one. 2012; 7(5):e36648. doi: 10.1371/journal.pone.0036648. [PMID: 22615788]
  • Michael Lohmann, Gudrun Walenda, Hatim Hemeda, Sylvia Joussen, Wolf Drescher, Stefan Jockenhoevel, Gabriele Hutschenreuter, Martin Zenke, Wolfgang Wagner. Donor age of human platelet lysate affects proliferation and differentiation of mesenchymal stem cells. PloS one. 2012; 7(5):e37839. doi: 10.1371/journal.pone.0037839. [PMID: 22662236]
  • Kanitsak Boonanantanasarn, Kajohnkiart Janebodin, Prapan Suppakpatana, Tawepong Arayapisit, Jit-aree Rodsutthi, Panjit Chunhabundit, Surintorn Boonanuntanasarn, Wanida Sripairojthikoon. Morinda citrifolia leaves enhance osteogenic differentiation and mineralization of human periodontal ligament cells. Dental materials journal. 2012; 31(5):863-71. doi: 10.4012/dmj.2012-053. [PMID: 23037852]
  • Chen-Chen Wu, Xiao-Bing Li, Tie-Suo Han, Peng Li, Guo-Wen Liu, Wei-Zhong Wang, Zhe Wang. Dietary pseudopurpurin effects on bone mineral density and bone geometry architecture in rats. International journal of molecular sciences. 2012; 13(3):3431-3443. doi: 10.3390/ijms13033431. [PMID: 22489160]
  • Neil Charles Wallace Mackenzie, Dongxing Zhu, Elspeth M Milne, Rob van 't Hof, Aline Martin, Leigh Darryl Quarles, Darryl Leigh Quarles, José Luis Millán, Colin Farquharson, Vicky Elisabeth MacRae. Altered bone development and an increase in FGF-23 expression in Enpp1(-/-) mice. PloS one. 2012; 7(2):e32177. doi: 10.1371/journal.pone.0032177. [PMID: 22359666]
  • Quan Yuan, Tadatoshi Sato, Michael Densmore, Hiroaki Saito, Christiane Schüler, Reinhold G Erben, Beate Lanske. Deletion of PTH rescues skeletal abnormalities and high osteopontin levels in Klotho-/- mice. PLoS genetics. 2012; 8(5):e1002726. doi: 10.1371/journal.pgen.1002726. [PMID: 22615584]
  • Niranjan K Pehere, Sreedhar Bojja, Geeta K Vemuganti, Pravin K Vaddavalli, Monica Samant, Subhadra Jalali, Manjushree Bhate. Opacification of intraocular lenses implanted during infancy: a clinicopathologic study of 4 explanted intraocular lenses. Ophthalmology. 2011 Nov; 118(11):2128-2132.e1. doi: 10.1016/j.ophtha.2011.05.012. [PMID: 21862135]
  • Daria Mamaeva, Chantal Ripoll, Claire Bony, Marisa Teigell, Florence E Perrin, Bernard Rothhut, Ivan Bieche, Rosette Lidereau, Alain Privat, Valérie Rigau, Hélène Guillon, Florence Vachiery-Lahaye, Daniele Noel, Luc Bauchet, Jean-Philippe Hugnot. Isolation of mineralizing Nestin+ Nkx6.1+ vascular muscular cells from the adult human spinal cord. BMC neuroscience. 2011 Oct; 12(?):99. doi: 10.1186/1471-2202-12-99. [PMID: 21985235]
  • Kristine M Wiren, Joel G Hashimoto, Anthony A Semirale, Xiao-Wei Zhang. Bone vs. fat: embryonic origin of progenitors determines response to androgen in adipocytes and osteoblasts. Bone. 2011 Oct; 49(4):662-72. doi: 10.1016/j.bone.2011.06.010. [PMID: 21704206]
  • Erzsébet Zavaczki, Viktória Jeney, Anupam Agarwal, Abolfazl Zarjou, Melinda Oros, Mónika Katkó, Zsuzsa Varga, György Balla, József Balla. Hydrogen sulfide inhibits the calcification and osteoblastic differentiation of vascular smooth muscle cells. Kidney international. 2011 Oct; 80(7):731-9. doi: 10.1038/ki.2011.212. [PMID: 21716261]
  • Qin Bian, Kuan Jia, Shu-Fen Liu, Bing Shu, Qian-Qian Liang, Chong-Jian Zhou, Quan Zhou, Yong-Jun Wang. Inhibitory effect of YQHYRJ recipe on osteoblast differentiation induced by BMP-2 in fibroblasts from posterior longitudinal ligament of mice. Die Pharmazie. 2011 Oct; 66(10):784-90. doi: ". [PMID: 22026161]
  • Tahereh Talaei-Khozani, Zahra Vojdani, Farzaneh Dehghani, Emad Heidari, Ebrahym Kharazinejad, Mohhamad Reza Panjehshahin. Toxic effects of Elaeagnus angustifolia fruit extract on chondrogenesis and osteogenesis in mouse limb buds. The Tokai journal of experimental and clinical medicine. 2011 Sep; 36(3):63-70. doi: ". [PMID: 21932186]
  • Brooke R Snyder, Pei-Hsun Cheng, Jinjing Yang, Shang-Hsun Yang, Anderson H C Huang, Anthony W S Chan. Characterization of dental pulp stem/stromal cells of Huntington monkey tooth germs. BMC cell biology. 2011 Sep; 12(?):39. doi: 10.1186/1471-2121-12-39. [PMID: 21910887]
  • Roz Alfred, Jaymi T Taiani, Roman J Krawetz, Akihiro Yamashita, Derrick E Rancourt, Michael S Kallos. Large-scale production of murine embryonic stem cell-derived osteoblasts and chondrocytes on microcarriers in serum-free media. Biomaterials. 2011 Sep; 32(26):6006-16. doi: 10.1016/j.biomaterials.2011.04.015. [PMID: 21620471]
  • Agbor Ndip, Alfred Williams, Edward B Jude, Ferdinand Serracino-Inglott, Steve Richardson, J V Smyth, Andrew J M Boulton, M Yvonne Alexander. The RANKL/RANK/OPG signaling pathway mediates medial arterial calcification in diabetic Charcot neuroarthropathy. Diabetes. 2011 Aug; 60(8):2187-96. doi: 10.2337/db10-1220. [PMID: 21659498]
  • Katarzyna Otulak, Grażyna Garbaczewska. Cellular localisation of calcium ions during potato hypersensitive response to Potato virus Y. Micron (Oxford, England : 1993). 2011 Jul; 42(5):381-91. doi: 10.1016/j.micron.2010.11.001. [PMID: 21227706]
  • Jiucheng He, Azucena H Kakazu, Nicolas G Bazan, Haydee E P Bazan. Aspirin-triggered lipoxin A4 (15-epi-LXA4) increases the endothelial viability of human corneas storage in Optisol-GS. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics. 2011 Jun; 27(3):235-41. doi: 10.1089/jop.2010.0187. [PMID: 21548792]
  • Hai Wu, Po Wang, Xiao Hu, Zong Dai, Xiaoyong Zou. Site-selective probe for investigating the asynchronous unfolding of domains in bovine serum albumin. Talanta. 2011 May; 84(3):881-6. doi: 10.1016/j.talanta.2011.02.027. [PMID: 21482297]
  • Mohamed T Abdel aziz, Mohamed F El Asmar, Hazem M Atta, Soheir Mahfouz, Hanan H Fouad, Nagwa K Roshdy, Laila A Rashed, Dina Sabry, Amira A Hassouna, Fatma M Taha. Efficacy of mesenchymal stem cells in suppression of hepatocarcinorigenesis in rats: possible role of Wnt signaling. Journal of experimental & clinical cancer research : CR. 2011 May; 30(?):49. doi: 10.1186/1756-9966-30-49. [PMID: 21545718]
  • Caitlin E Filby, Robert Williamson, Peter van Kooy, Alice Pébay, Mirella Dottori, Ngaire J Elwood, Faten Zaibak. Stimulation of Activin A/Nodal signaling is insufficient to induce definitive endoderm formation of cord blood-derived unrestricted somatic stem cells. Stem cell research & therapy. 2011 Apr; 2(2):16. doi: 10.1186/scrt57. [PMID: 21463501]
  • Sridhar Muthusami, Krishnamoorthy Senthilkumar, Chandragandan Vignesh, Ramachandran Ilangovan, Jone Stanley, Nagarajan Selvamurugan, Narasimhan Srinivasan. Effects of Cissus quadrangularis on the proliferation, differentiation and matrix mineralization of human osteoblast like SaOS-2 cells. Journal of cellular biochemistry. 2011 Apr; 112(4):1035-45. doi: 10.1002/jcb.23016. [PMID: 21308732]
  • Ying-xing Xu, Cheng-liang Wu, Yan Wu. [The expression and significance of Wnt/beta-catenin signal pathway protein in the effect of bushen huoxue granule containing serum on the osteoblast]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine. 2011 Apr; 31(4):537-41. doi: NULL. [PMID: 21608229]
  • Kenneth T Thurn, Hans Arora, Tatjana Paunesku, Aiguo Wu, Eric M B Brown, Caroline Doty, Jeff Kremer, Gayle Woloschak. Endocytosis of titanium dioxide nanoparticles in prostate cancer PC-3M cells. Nanomedicine : nanotechnology, biology, and medicine. 2011 Apr; 7(2):123-30. doi: 10.1016/j.nano.2010.09.004. [PMID: 20887814]
  • Satoshi Sera, Masakazu Ishikawa, Nobuo Adachi, Yuji Yasunaga, Mitsuo Ochi. Stem/progenitor cells in closed suction drainage fluid after hip arthroplasty. Acta orthopaedica. 2011 Apr; 82(2):217-22. doi: 10.3109/17453674.2011.566153. [PMID: 21434846]
  • Xue-Dong Li, Jian-Sheng Wang, Bo Chang, Bin Chen, Chun Guo, Guo-Qing Hou, Dong-Yang Huang, Shi-Xin Du. Panax notoginseng saponins promotes proliferation and osteogenic differentiation of rat bone marrow stromal cells. Journal of ethnopharmacology. 2011 Mar; 134(2):268-74. doi: 10.1016/j.jep.2010.11.075. [PMID: 21167926]
  • Benjamin Levi, Aaron W James, Emily R Nelson, Michelle Peng, Derrick C Wan, George W Commons, Min Lee, Benjamin Wu, Michael T Longaker. Acute skeletal injury is necessary for human adipose-derived stromal cell-mediated calvarial regeneration. Plastic and reconstructive surgery. 2011 Mar; 127(3):1118-1129. doi: 10.1097/prs.0b013e318205f274. [PMID: 21364415]
  • G Pachón-Peña, G Yu, A Tucker, X Wu, J Vendrell, B A Bunnell, J M Gimble. Stromal stem cells from adipose tissue and bone marrow of age-matched female donors display distinct immunophenotypic profiles. Journal of cellular physiology. 2011 Mar; 226(3):843-51. doi: 10.1002/jcp.22408. [PMID: 20857424]
  • Aaron W James, Benjamin Levi, Emily R Nelson, Michelle Peng, George W Commons, Min Lee, Benjamin Wu, Michael T Longaker. Deleterious effects of freezing on osteogenic differentiation of human adipose-derived stromal cells in vitro and in vivo. Stem cells and development. 2011 Mar; 20(3):427-39. doi: 10.1089/scd.2010.0082. [PMID: 20536327]
  • Tingjun Fan, Jun Zhao, Xiya Ma, Xiaohui Xu, Wenzhuo Zhao, Bin Xu. Establishment of a continuous untransfected human corneal endothelial cell line and its biocompatibility to denuded amniotic membrane. Molecular vision. 2011 Feb; 17(?):469-80. doi: NULL. [PMID: 21365020]
  • Fei Ding, Wei Liu, Jian-Xiong Diao, Ying Sun. Characterization of Alizarin Red S binding sites and structural changes on human serum albumin: a biophysical study. Journal of hazardous materials. 2011 Feb; 186(1):352-9. doi: 10.1016/j.jhazmat.2010.11.002. [PMID: 21112139]
  • Jeffery Ford, Asghar Hajibeigi, Michael Long, Lisa Hahner, Crystal Gore, Jer-Tseng Hsieh, Deborah Clegg, Joseph Zerwekh, Orhan K Oz. GPR30 deficiency causes increased bone mass, mineralization, and growth plate proliferative activity in male mice. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2011 Feb; 26(2):298-307. doi: 10.1002/jbmr.209. [PMID: 20734455]
  • Tahereh Talaei-Khozani, Malihezaman Monsefi, Mansoureh Ghasemi. Lectins influence chondrogenesis and osteogenesis in limb bud mesenchymal cells. Glycoconjugate journal. 2011 Feb; 28(2):89-98. doi: 10.1007/s10719-011-9326-5. [PMID: 21360166]
  • Hao Ai, Hai Bai, Cun-Bang Wang, Jian-Feng Ou, Qiang Zhao, Xia Han, Zhe Chen, Xiao-Yan Hu. [Expression characteristics of SDF-1 receptor CXCR4 in mesenchymal stem cells derived from human umbilical cord tissue]. Zhongguo shi yan xue ye xue za zhi. 2011 Feb; 19(1):169-73. doi: ". [PMID: 21362245]
  • Manisha C Yadav, Ana Maria Sper Simão, Sonoko Narisawa, Carmen Huesa, Marc D McKee, Colin Farquharson, José Luis Millán. Loss of skeletal mineralization by the simultaneous ablation of PHOSPHO1 and alkaline phosphatase function: a unified model of the mechanisms of initiation of skeletal calcification. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2011 Feb; 26(2):286-97. doi: 10.1002/jbmr.195. [PMID: 20684022]
  • Vikash Chandra, G Swetha, Sudhakar Muthyala, Amit K Jaiswal, Jayesh R Bellare, Prabha D Nair, Ramesh R Bhonde. Islet-like cell aggregates generated from human adipose tissue derived stem cells ameliorate experimental diabetes in mice. PloS one. 2011; 6(6):e20615. doi: 10.1371/journal.pone.0020615. [PMID: 21687731]
  • Anna Idelevich, Michael Kerschnitzki, Ron Shahar, Efrat Monsonego-Ornan. 1,25(OH)2D3 alters growth plate maturation and bone architecture in young rats with normal renal function. PloS one. 2011; 6(6):e20772. doi: 10.1371/journal.pone.0020772. [PMID: 21695192]
  • Feng Ge, Lixiang Jiang, Diqiu Liu, Chaoyin Chen. Interaction between alizarin and human serum albumin by fluorescence spectroscopy. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry. 2011; 27(1):79-84. doi: 10.2116/analsci.27.79. [PMID: 21233565]
  • Christian Niehage, Charlotte Steenblock, Theresia Pursche, Martin Bornhäuser, Denis Corbeil, Bernard Hoflack. The cell surface proteome of human mesenchymal stromal cells. PloS one. 2011; 6(5):e20399. doi: 10.1371/journal.pone.0020399. [PMID: 21637820]
  • Ryohei Kono, Yoshiharu Okuno, Ken-ichi Inada, Akihiko Tokuda, Hiroshi Hashizume, Munehito Yoshida, Misa Nakamura, Hirotoshi Utsunomiya. A Prunus mume extract stimulated the proliferation and differentiation of osteoblastic MC3T3-E1 cells. Bioscience, biotechnology, and biochemistry. 2011; 75(10):1907-11. doi: 10.1271/bbb.110264. [PMID: 21979066]
  • Cristina Zanini, Stefania Bruno, Giorgia Mandili, Denisa Baci, Francesco Cerutti, Giovanna Cenacchi, Leo Izzi, Giovanni Camussi, Marco Forni. Differentiation of mesenchymal stem cells derived from pancreatic islets and bone marrow into islet-like cell phenotype. PloS one. 2011; 6(12):e28175. doi: 10.1371/journal.pone.0028175. [PMID: 22194812]