metaraminol (BioDeep_00000016559)

Main id: BioDeep_00000002734

 


代谢物信息卡片


metaraminol

化学式: C9H13NO2 (167.09462380000002)
中文名称: 间羟胺
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C(C1=CC(=CC=C1)O)O)N
InChI: InChI=1S/C9H13NO2/c1-6(10)9(12)7-3-2-4-8(11)5-7/h2-6,9,11-12H,10H2,1H3/t6-,9-/m0/s1

描述信息

C - Cardiovascular system > C01 - Cardiac therapy > C01C - Cardiac stimulants excl. cardiac glycosides > C01CA - Adrenergic and dopaminergic agents
D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D013566 - Sympathomimetics
C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C87053 - Adrenergic Agonist
D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists
D002317 - Cardiovascular Agents > D014662 - Vasoconstrictor Agents
KEIO_ID M167

同义名列表

1 个代谢物同义名

metaraminol



数据库引用编号

16 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yugeesh R Lankadeva, Andrew D Cochrane, Bruno Marino, Naoya Iguchi, Sally G Hood, Rinaldo Bellomo, Clive N May, Roger G Evans. Strategies that improve renal medullary oxygenation during experimental cardiopulmonary bypass may mitigate postoperative acute kidney injury. Kidney international. 2019 06; 95(6):1338-1346. doi: 10.1016/j.kint.2019.01.032. [PMID: 31005272]
  • Chuixiu Huang, Knut Fredrik Seip, Astrid Gjelstad, Stig Pedersen-Bjergaard. Electromembrane extraction of polar basic drugs from plasma with pure bis(2-ethylhexyl) phosphite as supported liquid membrane. Analytica chimica acta. 2016 Aug; 934(?):80-7. doi: 10.1016/j.aca.2016.06.002. [PMID: 27506347]
  • Mayank Rashmi, D Swati. In silico drug re-purposing against African sleeping sickness using GlcNAc-PI de-N-acetylase as an experimental target. Computational biology and chemistry. 2015 Dec; 59 Pt A(?):87-94. doi: 10.1016/j.compbiolchem.2015.09.010. [PMID: 26476127]
  • Daniel J Warner, Hongming Chen, Louis-David Cantin, J Gerry Kenna, Simone Stahl, Clare L Walker, Tobias Noeske. Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals. 2012 Dec; 40(12):2332-41. doi: 10.1124/dmd.112.047068. [PMID: 22961681]
  • Einly Lim, Socrates Dokos, Robert F Salamonsen, Franklin L Rosenfeldt, Peter J Ayre, Nigel H Lovell. Numerical optimization studies of cardiovascular-rotary blood pump interaction. Artificial organs. 2012 May; 36(5):E110-24. doi: 10.1111/j.1525-1594.2012.01449.x. [PMID: 22489799]
  • Martyn Harvey, Grant Cave. Case report: successful lipid resuscitation in multi-drug overdose with predominant tricyclic antidepressant toxidrome. International journal of emergency medicine. 2012 Feb; 5(1):8. doi: 10.1186/1865-1380-5-8. [PMID: 22296992]
  • Ania L Manson, Rohit Juneja, Robert Self, Paul Farquhar-Smith, Fiona Macneill, Suranjith L Seneviratne. Anaphylaxis to Patent Blue V: a case series. Asia Pacific allergy. 2012 Jan; 2(1):86-9. doi: 10.5415/apallergy.2012.2.1.86. [PMID: 22348211]
  • E T Yamaguchi, M M Cardoso, M L Torres, R C Nascimento, M C Ribeiro, E Frerichs, D Payen. Serum oxytocin concentrations in elective caesarean delivery: a randomized comparison of three infusion regimens. International journal of obstetric anesthesia. 2011 Jul; 20(3):224-8. doi: 10.1016/j.ijoa.2011.03.004. [PMID: 21641198]
  • Mohammad Minakari, Leila Faiiaz, Mehdi Rowshandel, Ahmad Shavakhi. Comparison of the effect of midodrine versus octreotide on hemodynamic status in cirrhotic patients with ascites. Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences. 2011 Jan; 16(1):87-93. doi: . [PMID: 21448389]
  • Joseph Prandota. Mollaret meningitis may be caused by reactivation of latent cerebral toxoplasmosis. The International journal of neuroscience. 2009; 119(10):1655-92. doi: 10.1080/00207450802480044. [PMID: 19922380]
  • José Fernando Amaral Meletti, Reinaldo Vargas Bastos de Miranda. Amniotic fluid embolism during vaginal delivery under analgesia. Case report. Revista brasileira de anestesiologia. 2008 Jul; 58(4):397-402. doi: 10.1590/s0034-70942008000400010. [PMID: 19378589]
  • Han Liu, Fang Feng, Ming Ma, Shuangjin Cui, Darong Xie, Sizhi Xu. Pharmacokinetic study of three cardiovascular drugs by high-performance liquid chromatography using pre-column derivatization with 9,10-anthraquinone-2-sulfonyl chloride. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2007 Oct; 858(1-2):42-8. doi: 10.1016/j.jchromb.2007.08.004. [PMID: 17766197]
  • Li-Chao Hou, Shu-Zhi Li, Li-Ze Xiong, Shao-Yang Chen, Min Chen, Xi-Jing Zhang, Ting-Ting Huo, Qiang Wang, Ya-Li Wang, Wen-Neng Hu. Effect of dopamine and metaraminol on the renal function of patients with septic shock. Chinese medical journal. 2007 Apr; 120(8):680-3. doi: . [PMID: 17517184]
  • Xue-ling Fang, Qiang Fang, Guo-long Cai, Jing Yan. [Effect of fluid resuscitation on adhesion molecule and hemodynamics in patients with severe sepsis]. Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue. 2006 Sep; 18(9):539-41. doi: NULL. [PMID: 16959151]
  • D M Wood, K D Wright, A L Jones, P I Dargan. Metaraminol (Aramine) in the management of a significant amlodipine overdose. Human & experimental toxicology. 2005 Jul; 24(7):377-81. doi: 10.1191/0960327105ht538oa. [PMID: 16119252]
  • Bi-li Zhang, Zhi-jun Li, Lan-yun Song, Hong Zhou, Wen-hong Wang, Xuan Zhang. [Experimental study on prevention and treatment of focal segmental glomerulosclerosis with heparin]. Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue. 2004 Jan; 16(1):26-8. doi: . [PMID: 14706199]
  • Margit Pissarek, Johannes Ermert, Guido Oesterreich, Dirk Bier, Heinz H Coenen. Relative uptake, metabolism, and beta-receptor binding of (1R,2S)-4-(18)F-fluorometaraminol and (123)I-MIBG in normotensive and spontaneously hypertensive rats. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2002 Mar; 43(3):366-73. doi: NULL. [PMID: 11884497]
  • S A Ford, P C Kam, B A Baldo, M M Fisher. Anaphylactic or anaphylactoid reactions in patients undergoing cardiac surgery. Journal of cardiothoracic and vascular anesthesia. 2001 Dec; 15(6):684-8. doi: 10.1053/jcan.2001.28310. [PMID: 11748513]
  • W D Ngan Kee, K S Khaw, B B Lee, F F Ng, M M Wong. Randomized controlled study of colloid preload before spinal anaesthesia for caesarean section. British journal of anaesthesia. 2001 Nov; 87(5):772-4. doi: 10.1093/bja/87.5.772. [PMID: 11878530]
  • Y Takewa, T Seki, E Tatsumi, Y Taenaka, H Takano. Prostaglandin synthesis inhibitor improves hypotension during normothermic cardiopulmonary bypass. ASAIO journal (American Society for Artificial Internal Organs : 1992). 2001 Nov; 47(6):673-6. doi: 10.1097/00002480-200111000-00020. [PMID: 11730209]
  • D W Hill, W G Hyde, A J Kind, D Greulich, S Hopkins. Development of analytical methods for the detection of metaraminol in the horse. Journal of analytical toxicology. 2000 May; 24(4):281-8. doi: 10.1093/jat/24.4.281. [PMID: 10872576]
  • O Langer, H Valette, F Dollé, C Halldin, C Loc'h, C Fuseau, C Coulon, M Ottaviani, M Bottlaender, B Mazière, C Crouzel. High specific radioactivity (1R,2S)-4-[(18)F]fluorometaraminol: a PET radiotracer for mapping sympathetic nerves of the heart. Nuclear medicine and biology. 2000 Apr; 27(3):233-8. doi: 10.1016/s0969-8051(00)00082-2. [PMID: 10832079]
  • J C Yap, L A Critchley, S C Yu, R M Calcroft, J L Derrick. A comparison of three fluid-vasopressor regimens used to prevent hypotension during subarachnoid anaesthesia in the elderly. Anaesthesia and intensive care. 1998 Oct; 26(5):497-502. doi: 10.1177/0310057x9802600504. [PMID: 9807603]
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  • L A Critchley, F Conway. Hypotension during subarachnoid anaesthesia: haemodynamic effects of colloid and metaraminol. British journal of anaesthesia. 1996 May; 76(5):734-6. doi: 10.1093/bja/76.5.734. [PMID: 8688279]
  • K Någren, C Halldin, C G Swahn, T Suhara, L Farde. [11C]metaraminol, a false neurotransmitter: preparation, metabolite studies and positron emission tomography examination in monkey. Nuclear medicine and biology. 1996 Apr; 23(3):221-7. doi: 10.1016/0969-8051(95)02050-0. [PMID: 8782229]
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  • Y Ohmomo, A Yokoyama, K Kawai, Y Arano, K Horiuchi, C Tanaka, H Saji, K Torizuka. [125I] radioiodinated metaraminol: a new platelet-specific labeling agent. European journal of nuclear medicine. 1985; 10(5-6):269-75. doi: 10.1007/bf00254473. [PMID: 3987703]
  • R G Johnson, S E Carty, S Hayflick, A Scarpa. Mechanisms of accumulation of tyramine, metaraminol, and isoproterenol in isolated chromaffin granules and ghosts. Biochemical pharmacology. 1982 Mar; 31(5):815-23. doi: 10.1016/0006-2952(82)90468-3. [PMID: 7082350]
  • D Davila, R Ivanov, T Davila. Inhibitory effect of two steroids on the accumulation of [3H]metaraminol by rat tissues in vivo. The Journal of pharmacy and pharmacology. 1981 Jun; 33(6):362-4. doi: 10.1111/j.2042-7158.1981.tb13804.x. [PMID: 6115007]
  • H J Houthoff, K G Go, I Molenaar. The permeability of the blood-brain barrier in acute hypertension. Comparison of an endogenous and exogenous protein tracer. Acta neuropathologica. Supplementum. 1981; 7(?):13-6. doi: 10.1007/978-3-642-81553-9_4. [PMID: 6939220]
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  • H Seneca. Gram-negative sepsis: part II. Management. Comprehensive therapy. 1977 Aug; 3(8):66-74. doi: NULL. [PMID: 884949]
  • A H Anton, A I Berk. Distribution of metaraminol and its relation to norepinephrine. European journal of pharmacology. 1977 Jul; 44(2):161-7. doi: 10.1016/0014-2999(77)90102-9. [PMID: 885165]
  • K M Braunstein, K E Sarji, J Kleinfelder, H B Schraibman, J A Colwell, K Eurenius. The effects of dopamine on human platelet aggregation, in vitro. The Journal of pharmacology and experimental therapeutics. 1977 Feb; 200(2):449-57. doi: NULL. [PMID: 839449]
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  • M A Saleh, O A Zaki, A M Kamel, K M Ghoneim, N A El-Damarawy. Effects of metaraminol, insulin and trasylol on the responses to haemorrhage in dogs. African journal of medicine and medical sciences. 1976 Sep; 5(3):229-34. doi: . [PMID: 829734]
  • P Hirszel, R H Martin, M W Mizell, K D Nolph. Uremic autonomic neuropathy: evaluation of ephedrine sulphate therapy for hemodialysis-induced hypotension. International urology and nephrology. 1976; 8(4):313-21. doi: 10.1007/bf02082096. [PMID: 1017920]
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  • J H Moyer, L C Mills. Vasopressors for treating shock. Postgraduate medicine. 1974 Aug; 56(2):172-80. doi: 10.1080/00325481.1974.11713830. [PMID: 4855378]
  • M Levitt, W R Cumiskey, L Shargel. Studies on the physiologic disposition and activity of phenylpropanolamines in the mouse. Drug metabolism and disposition: the biological fate of chemicals. 1974 Mar; 2(2):187-93. doi: NULL. [PMID: 4150999]
  • M H Weil, H Shubin. Treatment of shock caused by bacterial infections. California medicine. 1973 Nov; 119(5):7-13. doi: NULL. [PMID: 4755702]
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  • S K Gomer, B G Zimmerman. Effect of angiotensin II on uptake and release of dl- 3 H-metaraminol. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 1973 Mar; 142(3):787-92. doi: 10.3181/00379727-142-37117. [PMID: 4348092]
  • W A Saad, L A Camargo, C R Silva Netto, J Antunes-Rodrigues, M R Covian. Proceedings: Natriuresis, kaliuresis and urinary volume changes induced by cholinergic and adrenergic stimulation of the septal area of the rat brain. Acta physiologica latino americana. 1973; 23(6):477-8. doi: NULL. [PMID: 4153019]
  • J Dodsworth, J H James, M G Cummings, J E Fischer. Diagnosis and therapy of the hepatorenal syndrome: a tentative classification. Surgical forum. 1973; 24(?):396-7. doi: NULL. [PMID: 4806037]
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