Salbutamol (BioDeep_00000001514)

human metabolite Chemicals and Drugs Volatile Flavor Compounds

代谢物信息卡片

4-Hydroxy-3-hydroxymethyl-alpha-((tert-butylamino)methyl)benzyl alcohol

化学式: C13H21NO3 (239.1521356)
中文名称: 甲醇中沙丁胺醇溶液标准物质, 左旋沙丁胺醇, 沙丁胺醇
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C)(C)NCC(C1=CC(=C(C=C1)O)CO)O
InChI: InChI=1S/C13H21NO3/c1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15/h4-6,12,14-17H,7-8H2,1-3H3

描述信息

Salbutamol is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. It is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity for pulmonary beta receptors versus beta1-adrenergic receptors located in the heart. Salbutamol is formulated as a racemic mixture of the R- and S-isomers. The R-isomer has 150 times greater affinity for the beta2-receptor than the S-isomer and the S-isomer has been associated with toxicity. This lead to the development of levalbuterol, the single R-isomer of salbutamol. However, the high cost of levalbuterol compared to salbutamol has deterred wide-spread use of this enantiomerically pure version of the drug. Salbutamol is generally used for acute episodes of bronchospasm caused by bronchial asthma, chronic bronchitis and other chronic bronchopulmonary disorders such as chronic obstructive pulmonary disorder (COPD). It is also used prophylactically for exercise-induced asthma
Salbutamol or albuterol is a short-acting beta 2-adrenergic receptor agonist used for the relief of bronchospasm in conditions such as asthma. -- Pubchem [HMDB]
R - Respiratory system > R03 - Drugs for obstructive airway diseases > R03C - Adrenergics for systemic use > R03CC - Selective beta-2-adrenoreceptor agonists
R - Respiratory system > R03 - Drugs for obstructive airway diseases > R03A - Adrenergics, inhalants > R03AC - Selective beta-2-adrenoreceptor agonists
D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D001993 - Bronchodilator Agents
C78273 - Agent Affecting Respiratory System > C29712 - Anti-asthmatic Agent > C319 - Bronchodilator
C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C87053 - Adrenergic Agonist
D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists
COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials
D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents
D012102 - Reproductive Control Agents > D015149 - Tocolytic Agents
Same as: D08124
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
Salbutamol (Albuterol) is a short-acting beta-2 adrenergic receptor agonist with oral activity. Salbutamol promotes tumorigenesis of gastric cancer cells through the β2-AR/ERK/EMT pathway. Salbutamol is used to study bronchospasms caused by asthma and chronic obstructive pulmonary disease (COPD)[1][2].
Salbutamol (Albuterol) is a short-acting beta-2 adrenergic receptor agonist with oral activity. Salbutamol promotes tumorigenesis of gastric cancer cells through the β2-AR/ERK/EMT pathway. Salbutamol is used to study bronchospasms caused by asthma and chronic obstructive pulmonary disease (COPD)[1][2].

同义名列表

105 个代谢物同义名

4-Hydroxy-3-hydroxymethyl-alpha-((tert-butylamino)methyl)benzyl alcohol; DL-N-Tert-butyl-2-(4-hydroxy-3-hydroxymethylphenyl)-2-hydroxyethylamine; 2-t-Butylamino-1-(4-hydroxy-3-hydroxy-3-hydroxymethyl)phenylethanol; Alpha-((tert-butylamino)methyl)-4-hydroxy-m-xylene-alpha,alpha-diol; 1-(Tert-butylaminomethyl)-4-hydroxy-m-xylene-alpha1,alpha3-diol; 2-(Tert-butylamino)-1-(4-hydroxy-3-hydroxymethylphenyl)ethanol; 4-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol; Salbutamol free base; Arubendol-salbutamol; Volare albuterol hfa; Salbutamol sulphate; Volare easi-breathe; Salbutamol sulfate; Ventolin rotacaps; Albuterol sulfate; Proventil inhaler; Ventolin inhaler; Alti-salbutamol; Asmol uni-dose; (-)-Salbutamol; (L)-Albuterol; Proventil hfa; DL-Salbutamol; Broncho-spray; DL-Albuterol; Levalbuterol; Broncovaleas; R-Salbutamol; Salbutamolum; Salbu-fatol; Sultanol N; Salbuhexal; Ventiloboi; Salbutamol; Novosalmol; Servitamol; Salbutalan; Salbu-basf; Ventodisks; Cobutolin; Dilatamol; Buto-asma; Pneumolat; Ventoline; Salbusian; Salmaplon; Vencronyl; Salbuvent; Butohaler; Albuterol; Proventil; Salbutol; Grafalin; Salbetol; Salbuven; Salbulin; Ventilan; Farcolin; Sultanol; Tobybron; Libretin; Ventolin; Saventol; Sallbupp; Buventol; Salbutan; Salbupur; Gerivent; Suprasma; Asthalin; Respolin; Butovent; Ventamol; Asmatol; Salomol; Asmasal; Aerolin; Salamol; Asmaven; Asmidon; Parasma; Medolin; Asmanil; Salbron; Sabutal; Almotex; Theosal; Butamol; Zaperin; Asmadil; Bronter; Butotal; Anebron; Salvent; Bugonol; Volmax; Spreor; Respax; Asmol; Bumol; Mozal; Suxar; AH-3365; R-Salbutamol; Salbutamol

数据库引用编号

24 个数据库交叉引用编号

ChEBI: CHEBI:2549
ChEBI: CHEBI:8746
KEGG: C11770
PubChem: 2083
HMDB: HMDB0001937
DrugBank: DB01001
ChEMBL: CHEMBL714
Wikipedia: Albuterol
MeSH: Albuterol
foodb: FDB022752
chemspider: 1999
CAS: 1219798-60-3
CAS: 148563-15-9
CAS: 34391-04-3
CAS: 18559-94-9
CAS: 35763-26-9
PMhub: MS000000684
PubChem: 13934
PDB-CCD: 68H
NIKKAJI: J428.072E
RefMet: Salbutamol
medchemexpress: HY-B1037
CAS: 51022-70-9
KNApSAcK: 8746

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

9606 - Homo sapiens: -

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Hua Li, Tao Dong, Jinling Luan. Efficacy and safety of fluticasone propionate/salmeterol and fluticasone propionate monotherapy in step-up treatment of childhood asthma: A systematic review and meta-analysis. Heart & lung : the journal of critical care. 2023 Sep; 63(?):23-34. doi: 10.1016/j.hrtlng.2023.09.004. [PMID: 37740997]
Qin Qin Gong, Justin Yong Soon Tay, Natalia Veronica, Jian Xu, Paul Wan Sia Heng, Yong Ping Zhang, Celine Valeria Liew. Surface Modification of lactose carrier particles using a fluid bed coater to improve fine particle fraction for dry powder inhalers. Pharmaceutical development and technology. 2023 Feb; 28(2):164-175. doi: 10.1080/10837450.2023.2171434. [PMID: 36683577]
Dany Silva, Katarzyna Kacprzak, Clara Quintas, Jorge Gonçalves, Paula Fresco. Activation of β-Adrenoceptors Promotes Lipid Droplet Accumulation in MCF-7 Breast Cancer Cells via cAMP/PKA/EPAC Pathways. International journal of molecular sciences. 2023 Jan; 24(1):. doi: 10.3390/ijms24010767. [PMID: 36614209]
Noémie Penoy, Kouka Luc Delma, Hermane Avohou Tonakpon, Bruno Grignard, Brigitte Evrard, Géraldine Piel. An innovative one step green supercritical CO2 process for the production of liposomes co-encapsulating both a hydrophobic and a hydrophilic compound for pulmonary administration. International journal of pharmaceutics. 2022 Nov; 627(?):122212. doi: 10.1016/j.ijpharm.2022.122212. [PMID: 36150416]
Morten Hostrup, Jakob Grunnet Knudsen, Caroline Maag Kristensen, Søren Jessen, Henriette Pilegaard, Jens Bangsbo. Beta2 -agonist increases skeletal muscle interleukin 6 production and release in response to resistance exercise in men. Scandinavian journal of medicine & science in sports. 2022 Jul; 32(7):1099-1108. doi: 10.1111/sms.14171. [PMID: 35460295]
Glenn A Jacobson, Morten Hostrup. The salmeterol anomaly and the need for a urine threshold. Drug testing and analysis. 2022 Jun; 14(6):997-1003. doi: 10.1002/dta.2810. [PMID: 32314556]
Olivia L Ramey, Armando Silva Almodóvar, Milap C Nahata. Medication adherence in Medicare-enrolled older adults with asthma before and during the coronavirus disease 2019 pandemic. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2022 05; 128(5):561-567.e1. doi: 10.1016/j.anai.2022.02.010. [PMID: 35227901]
Graham Johnson, Andrew Tabner, Apostolos Fakis, Rachelle Sherman, Victoria Chester, Elizabeth Bedford, Richard Jackson, Hari Ratan, Suzanne Mason. Salbutamol for analgesia in renal colic: study protocol for a prospective, randomised, placebo-controlled phase II trial (SARC). Trials. 2022 Apr; 23(1):352. doi: 10.1186/s13063-022-06225-9. [PMID: 35468847]
Jinxuan Liang, Zhiwei Liu, Haihuan Xie, Yalin Fang, Qiqi Quan, Xing Shen, Hongtao Lei, Zhenlin Xu, Xiangmei Li. Ultrasensitive Magnetic Assisted Lateral Flow Immunoassay Based on Chiral Monoclonal Antibody against R-(-)-Salbutamol of Broad-Specificity for 38 β-Agonists Detection in Swine Urine and Pork. Journal of agricultural and food chemistry. 2022 Apr; 70(13):4112-4122. doi: 10.1021/acs.jafc.2c00875. [PMID: 35344358]
Perrine Courlet, Thierry Buclin, Jérôme Biollaz, Irene Mazzoni, Olivier Rabin, Monia Guidi. Model-based meta-analysis of salbutamol pharmacokinetics and practical implications for doping control. CPT: pharmacometrics & systems pharmacology. 2022 04; 11(4):469-481. doi: 10.1002/psp4.12773. [PMID: 35315251]
Ahmed Samir, Hesham Salem, Mohammed Abdelkawy. Optimization of two charge transfer reactions for colorimetric determination of two beta 2 agonist drugs, salmeterol xinafoate and salbutamol, in pharmaceutical and biological samples. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2022 Mar; 269(?):120747. doi: 10.1016/j.saa.2021.120747. [PMID: 34952438]
Martina Zügel, Daniel A Bizjak, Dorle Nussbaumer, Kay Winkert, Kensuke Takabayashi, Johannes Kirsten, Mickel Washington, Gunnar Treff, Jens Dreyhaupt, Luise Steeb, Patrick Diel, Maria Kristina Parr, Jürgen M Steinacker, Hasema Persch. The ELSA trial: single versus combinatory effects of non-prohibited beta-2 agonists on skeletal muscle metabolism, cardio-pulmonary function and endurance performance-study protocol for a randomized 4-way balanced cross-over trial. Trials. 2021 Dec; 22(1):903. doi: 10.1186/s13063-021-05862-w. [PMID: 34895300]
Salah M Seif, Elnady Ma, Hoda Rabea, Haitham Saeed, Mohamed E A Abdelrahim. Aerosol delivery of inhalation devices with different add-on connections to invasively ventilated COPD subjects: An in-vivo study. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2021 Dec; 167(?):105988. doi: 10.1016/j.ejps.2021.105988. [PMID: 34492291]
Marcella Granfone, Julie M Walker. Acute nontraumatic rhabdomyolysis in a Greyhound after albuterol toxicosis. Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001). 2021 Nov; 31(6):818-822. doi: 10.1111/vec.13137. [PMID: 34450682]
Muhammad Waqas Sadiq, Olaf Holz, Birthe D Ellinghusen, Cornelia Faulenbach, Meike Müller, Philipp Badorrek, Ulf G Eriksson, Markus Fridén, Stina Stomilovic, Anders J Lundqvist, Jens M Hohlfeld. Lung pharmacokinetics of inhaled and systemic drugs: A clinical evaluation. British journal of pharmacology. 2021 11; 178(22):4440-4451. doi: 10.1111/bph.15621. [PMID: 34250588]
Mona A Abdelrahman, Mohamed E Abdelrahim, Haitham Saeed. Impact of different nebulisers' connections on aerosol therapy. International journal of clinical practice. 2021 Oct; 75(10):e14493. doi: 10.1111/ijcp.14493. [PMID: 34117678]
Xianrong Du, Hongju Bao, Daguo Zhao. Efficacy and safety of combined doxofylline and salbutamol in treatment of acute exacerbation of chronic obstructive pulmonary disease. Revista da Associacao Medica Brasileira (1992). 2021 Sep; 67(9):1256-1260. doi: 10.1590/1806-9282.20210429. [PMID: 34816917]
Ankit Tripathi, Bhuvnesh Kumar, Sarada S K Sagi. Hypoxia-mediated alterations in pulmonary surfactant protein expressions: Beneficial effects of quercetin prophylaxis. Respiratory physiology & neurobiology. 2021 09; 291(?):103695. doi: 10.1016/j.resp.2021.103695. [PMID: 34052411]
Søren B Poulsen, Lei Cheng, David Penton, Marleen L A Kortenoeven, Vladimir V Matchkov, Johannes Loffing, Robert Little, Sathish K Murali, Robert A Fenton. Activation of the kidney sodium chloride cotransporter by the β2-adrenergic receptor agonist salbutamol increases blood pressure. Kidney international. 2021 08; 100(2):321-335. doi: 10.1016/j.kint.2021.04.021. [PMID: 33940111]
Panagiotis Sakellariou, Michael Petrou, Emmanouil Lyris, Maria Tsivou, Argyro Fragkaki, Polyxeni Kiousi, Yiannis S Angelis, Constantinos Pistos. Determination of salmeterol, α-hydroxysalmeterol and fluticasone propionate in human urine and plasma for doping control using UHPLC-QTOF-MS. Biomedical chromatography : BMC. 2021 Aug; 35(8):e5114. doi: 10.1002/bmc.5114. [PMID: 33720401]
Matthew A Bailey. Salbutamol and salt-sensitive hypertension. Kidney international. 2021 08; 100(2):272-275. doi: 10.1016/j.kint.2021.05.023. [PMID: 34294206]
Olga L Guijon, Tricia Morphew, Louis Ehwerhemuepha, Stanley P Galant. Evaluating the impact of coronavirus disease 2019 on asthma morbidity: A comprehensive analysis of potential influencing factors. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2021 07; 127(1):91-99. doi: 10.1016/j.anai.2021.03.018. [PMID: 33775900]
V P Chandrasekaran, Anand Parthasarathy, Balaji Muruga, Senthamil, Tharanesh. Lipid emulsion in theophylline and salbutamol overdose: Lipid sink theory (MS 25092). The American journal of emergency medicine. 2021 07; 45(?):632. doi: 10.1016/j.ajem.2020.11.040. [PMID: 33323277]
Priya Venkatesan. 2021 American Thoracic Society International Conference. The Lancet. Respiratory medicine. 2021 07; 9(7):e65-e66. doi: 10.1016/s2213-2600(21)00260-5. [PMID: 34087099]
Mina Nicola, Raghda R S Hussein, Youssef M A Soliman, Mohamed Abdelrahim. Effect of different accessory devices on the dose delivered from pressurised metred-dose inhalers. International journal of clinical practice. 2021 Jun; 75(6):e14157. doi: 10.1111/ijcp.14157. [PMID: 33763954]
Craig D Nowadly, Shu-Yi Liao, John S Rose. Effects of Continuous Albuterol Inhalation on Serum Metabolome in Healthy Subjects: More Than Just Lactic Acid. Journal of clinical pharmacology. 2021 05; 61(5):649-655. doi: 10.1002/jcph.1781. [PMID: 33128239]
Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
Yasmin M Madney, Nabila Ibrahim Laz, Ahmed A Elberry, Hoda Rabea, Mohamed E A Abdelrahim. The impact of changing patient interfaces on delivering aerosol with titrated oxygen in the high flow system. International journal of clinical practice. 2021 Apr; 75(4):e13898. doi: 10.1111/ijcp.13898. [PMID: 33280194]
Søren Jessen, Victoria Becker, Sebastian Rzeppa, Vibeke Backer, Kasper Høtoft Bengtsen, Ingunn Hullstein, Yvette Dehnes, Morten Hostrup. Pharmacokinetics of salmeterol and its main metabolite α-hydroxysalmeterol after acute and chronic dry powder inhalation in exercising endurance-trained men: Implications for doping control. Drug testing and analysis. 2021 Apr; 13(4):747-761. doi: 10.1002/dta.2978. [PMID: 33210444]
Marc Mac Giolla Eain, Andrew O'Sullivan, Mary Joyce, Ronan MacLoughlin. In vitro evaluation of disposable transport ventilators with combination aerosol therapy. BMJ open respiratory research. 2021 Mar; 8(1):. doi: 10.1136/bmjresp-2020-000739. [PMID: 33771812]
Tetsuro Maeda, Janvi Paralkar, Toshiki Kuno, Paru Patrawalla. Inhaled Albuterol Use and Impaired Lactate Clearance in Patients With Sepsis: A Retrospective Cohort Study. Journal of intensive care medicine. 2021 Mar; 36(3):284-289. doi: 10.1177/0885066619901095. [PMID: 31964210]
Jinyan Zhang, Yihua Wei, Suyan Qiu, Yan Xiong. A highly selective and simple fluorescent probe for salbutamol detection based on thioglycolic acid-capped CdTe quantum dots. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy. 2021 Feb; 247(?):119107. doi: 10.1016/j.saa.2020.119107. [PMID: 33166780]
Vorakamol Phoophiboon, Parima Singhagowinta, Sangdao Boonkaya, Thitiwat Sriprasart. Salbutamol-induced lactic acidosis in status asthmaticus survivor. BMC pulmonary medicine. 2021 Jan; 21(1):23. doi: 10.1186/s12890-021-01404-x. [PMID: 33435939]
Chuanlin Zhang, Jie Mi, Zeju Zhang, Xueqin Wang, Yunxiao Zhu, Xinyi Luo, Ruiying Gan, Xiaoya Chen, Yujun Zou. The Clinical Practice and Best Aerosol Delivery Location in Intubated and Mechanically Ventilated Patients: A Randomized Clinical Trial. BioMed research international. 2021; 2021(?):6671671. doi: 10.1155/2021/6671671. [PMID: 33884269]
Zhizeng Wang, Qianqwen Zhou, Yafei Guo, Hangzhan Hu, Zhi Zheng, Shulian Li, Yaohui Wang, Yuanfang Ma. Rapid Detection of Ractopamine and Salbutamol in Swine Urine by Immunochromatography Based on Selenium Nanoparticles. International journal of nanomedicine. 2021; 16(?):2059-2070. doi: 10.2147/ijn.s292648. [PMID: 33727813]
Ajay K Medipally, Min Xiao, Brad H Rovin, Anjali A Satoskar, Iouri Ivanov, Shahzeb Qaisar, Sergey V Brodsky. Role of glomerular filtration rate-modifying drugs in the development of anticoagulant-related nephropathy. Physiological reports. 2021 01; 9(1):e14697. doi: 10.14814/phy2.14697. [PMID: 33427414]
Emiliana R Meroni, Roxanna Khorzad, Kiko Bracker, Virginia Sinnott-Stutzman. Retrospective evaluation of albuterol inhalant exposure in dogs: 36 cases (2007-2017). Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001). 2021 Jan; 31(1):86-93. doi: 10.1111/vec.13012. [PMID: 33118712]
Kesanee Chaicoming, Aroonwan Preutthipan, Anusorn Adirekkittikun, Malinee Nugboon. Homemade valved holding chambers for children with airway hyperresponsiveness: A randomized crossover trial. Pediatric pulmonology. 2021 01; 56(1):49-56. doi: 10.1002/ppul.25123. [PMID: 33150727]
Lingdi Zhao, Huanying Zhou, Tieqiang Sun, Wentao Liu, Hongwei He, Baoan Ning, Shuang Li, Yuan Peng, Dianpeng Han, Zunquan Zhao, Jiansheng Cui, Zhixian Gao. Complete antigen-bridged DNA strand displacement amplification immuno-PCR assay for ultrasensitive detection of salbutamol. The Science of the total environment. 2020 Dec; 748(?):142330. doi: 10.1016/j.scitotenv.2020.142330. [PMID: 33113707]
V P Chandrasekaran, Anand Parthasarathy, Balaji Muruga, Senthamil, Tharanesh. Theophylline toxicity: Successful management of a patient with distributive shock secondary to drug overdose. The American journal of emergency medicine. 2020 11; 38(11):2491.e1-2491.e2. doi: 10.1016/j.ajem.2020.05.112. [PMID: 32826106]
Andrew G Weber, Alice S Chau, Mikala Egeblad, Betsy J Barnes, Tobias Janowitz. Nebulized in-line endotracheal dornase alfa and albuterol administered to mechanically ventilated COVID-19 patients: a case series. Molecular medicine (Cambridge, Mass.). 2020 09; 26(1):91. doi: 10.1186/s10020-020-00215-w. [PMID: 32993479]
Emmanuel Montassier, Loic Lemoine, Jean Benoit Hardouin, Patrick Rossignol, Matthieu Legrand. Insulin glucose infusion versus nebulised salbutamol versus combination of salbutamol and insulin glucose in acute hyperkalaemia in the emergency room: protocol for a randomised, multicentre, controlled study (INSAKA). BMJ open. 2020 08; 10(8):e039277. doi: 10.1136/bmjopen-2020-039277. [PMID: 32847923]
Keigo Nakayama, Hidetaka Kamimura, Hiroshi Suemizu, Nao Yoneda, Megumi Nishiwaki, Kazuhiko Iwamoto, Mari Mizunaga, Tamotsu Negoro, Soichiro Ito, Hiroshi Yamazaki, Yukihiro Nomura. Predicted values for human total clearance of a variety of typical compounds with differently humanized-liver mouse plasma data. Drug metabolism and pharmacokinetics. 2020 Aug; 35(4):389-396. doi: 10.1016/j.dmpk.2020.05.004. [PMID: 32690433]
Christopher D Codispoti, Sindhura Bandi, Payal Patel, Mahboobeh Mahdavinia. Clinical course of asthma in 4 cases of coronavirus disease 2019 infection. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2020 08; 125(2):208-210. doi: 10.1016/j.anai.2020.05.009. [PMID: 32437838]
Israel Amirav, Michael T Newhouse. COVID-19: Time to embrace MDI+ valved-holding chambers!. The Journal of allergy and clinical immunology. 2020 08; 146(2):331. doi: 10.1016/j.jaci.2020.04.046. [PMID: 32482527]
A M Diezma-Martín, M I Morales-Casado, N García-Alvarado, A Vadillo Bermejo, N López-Ariztegui, M A Sepúlveda Berrocal. [Tremor and ataxia in COVID-19]. Neurologia (Barcelona, Spain). 2020 Jul; 35(6):409-410. doi: 10.1016/j.nrl.2020.06.005. [PMID: 32571554]
Ronald A Strauss. Subcutaneous terbutaline as an alternative to aerosolized albuterol. The journal of allergy and clinical immunology. In practice. 2020 Jul; 8(7):2450. doi: 10.1016/j.jaip.2020.04.015. [PMID: 32336646]
Marcus S Shaker, John Oppenheimer, Mitchell Grayson, David Stukus, Nicholas Hartog, Elena W Y Hsieh, Nicholas Rider, Cullen M Dutmer, Timothy K Vander Leek, Harold Kim, Edmond S Chan, Doug Mack, Anne K Ellis, David Lang, Jay Lieberman, David Fleischer, David B K Golden, Dana Wallace, Jay Portnoy, Giselle Mosnaim, Matthew Greenhawt. Reply to 'Subcutaneous terbutaline as an alternative to aerosolized albuterol'. The journal of allergy and clinical immunology. In practice. 2020 Jul; 8(7):2450-2452. doi: 10.1016/j.jaip.2020.04.016. [PMID: 32340824]
Abril Carbajal-García, Jorge Reyes-García, María F Casas-Hernández, Edgar Flores-Soto, Verónica Díaz-Hernández, Héctor Solís-Chagoyán, Bettina Sommer, Luis M Montaño. Testosterone augments β2 adrenergic receptor genomic transcription increasing salbutamol relaxation in airway smooth muscle. Molecular and cellular endocrinology. 2020 06; 510(?):110801. doi: 10.1016/j.mce.2020.110801. [PMID: 32278021]
Qian Wu, Qing Song, Xinxin Wang, Li Yao, Jianguo Xu, Jianfeng Lu, Guodong Liu, Wei Chen. Simultaneous Detection of Multiple β-Adrenergic Agonists with 2-Directional Lateral Flow Strip Platform. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry. 2020 Jun; 36(6):653-658. doi: 10.2116/analsci.19p218. [PMID: 31656246]
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