flumequine (BioDeep_00000014933)

 

Secondary id: BioDeep_00000017996

natural product


代谢物信息卡片


flumequine

化学式: C14H12FNO3 (261.0801174)
中文名称: 氟甲喹
谱图信息: 最多检出来源 Homo sapiens(general) 2.46%

分子结构信息

SMILES: C12C(C(=CN3C(CCC(=C31)C=C(C=2)F)C)C(=O)O)=O
InChI: InChI=1S/C14H12FNO3/c1-7-2-3-8-4-9(15)5-10-12(8)16(7)6-11(13(10)17)14(18)19/h4-7H,2-3H2,1H3,(H,18,19)

描述信息

J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01M - Quinolone antibacterials
D000970 - Antineoplastic Agents > D059003 - Topoisomerase Inhibitors > D059005 - Topoisomerase II Inhibitors
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D024841 - Fluoroquinolones
C254 - Anti-Infective Agent > C258 - Antibiotic > C795 - Quinolone Antibiotic
D004791 - Enzyme Inhibitors
CONFIDENCE standard compound; INTERNAL_ID 1030
CONFIDENCE standard compound; INTERNAL_ID 8533
CONFIDENCE standard compound; EAWAG_UCHEM_ID 3642

同义名列表

1 个代谢物同义名

flumequine



数据库引用编号

28 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • María Ramos-Payán, Juan Antonio Ocaña-González, Rut Fernández-Torres, Miguel Ángel Bello-López. A Method for the Determination of Veterinary Drugs from Different Therapeutic Classes in Animal Urine. Journal of chromatographic science. 2020 Jan; 58(2):127-135. doi: 10.1093/chromsci/bmz084. [PMID: 32154562]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • H Madej-Śmiechowska, A Orzoł, A Jasiecka-Mikołajczyk, H Ziółkowski, J J Jaroszewski. Differences in the pharmacokinetics of flumequine after single and continuous oral administration in non-fasted broiler chickens. Polish journal of veterinary sciences. 2018 Sep; 21(3):631-634. doi: 10.24425/124298. [PMID: 30468341]
  • Zhao-Hong Hu, Yang-Guang Wang, Huo-Xi Jin, Xiao-Kun Ouyang, Wei-Jian Wu. Analysis of flumequine enantiomers in rat plasma by UFLC-ESI-MS/MS. Chirality. 2016 11; 28(11):737-743. doi: 10.1002/chir.22654. [PMID: 27791319]
  • N Xu, J Dong, Y Yang, Q Yang, Y Liu, X Ai. Pharmacokinetics and bioavailability of flumequine in blunt snout bream (Megalobrama amblycephala) after intravascular and oral administrations. Journal of veterinary pharmacology and therapeutics. 2016 Apr; 39(2):191-5. doi: 10.1111/jvp.12261. [PMID: 26411430]
  • Marte Kaldestad, Gyri T Haugland, Anita Rønneseth, Heidrun I Wergeland, Ole Bent Samuelsen. Antibiotic uptake by cultured Atlantic cod leucocytes and effect on intracellular Francisella noatunensis subsp. noatunensis replication. Diseases of aquatic organisms. 2014 Feb; 108(1):11-21. doi: 10.3354/dao02696. [PMID: 24492050]
  • C Ferraresi, L Lucatello, V Meucci, L Intorre, G Grilli, A Piccirillo, E Russo, R Villa, C Montesissa, P Cagnardi. Pharmacokinetic/pharmacodynamic evaluation of the efficacy of flumequine in treating colibacillosis in turkeys. Poultry science. 2013 Dec; 92(12):3158-65. doi: 10.3382/ps.2013-03460. [PMID: 24235225]
  • Alketa Tarushi, Kostas Lafazanis, Jakob Kljun, Iztok Turel, Anastasia A Pantazaki, George Psomas, Dimitris P Kessissoglou. First- and second-generation quinolone antibacterial drugs interacting with zinc(II): structure and biological perspectives. Journal of inorganic biochemistry. 2013 Apr; 121(?):53-65. doi: 10.1016/j.jinorgbio.2012.12.009. [PMID: 23353082]
  • Evropi Chalkidou, Franc Perdih, Iztok Turel, Dimitris P Kessissoglou, George Psomas. Copper(II) complexes with antimicrobial drug flumequine: structure and biological evaluation. Journal of inorganic biochemistry. 2012 Aug; 113(?):55-65. doi: 10.1016/j.jinorgbio.2012.03.005. [PMID: 22694822]
  • Huan Yu, Yanfei Tao, Dongmei Chen, Yuanhu Pan, Zhenli Liu, Yulian Wang, Lingli Huang, Menghong Dai, Dapeng Peng, Xu Wang, Zonghui Yuan. Simultaneous determination of fluoroquinolones in foods of animal origin by a high performance liquid chromatography and a liquid chromatography tandem mass spectrometry with accelerated solvent extraction. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2012 Feb; 885-886(?):150-9. doi: 10.1016/j.jchromb.2011.12.016. [PMID: 22230742]
  • Reza Ghanbarpour, Shirin Daneshdoost. Identification of shiga toxin and intimin coding genes in Escherichia coli isolates from pigeons (Columba livia) in relation to phylotypes and antibiotic resistance patterns. Tropical animal health and production. 2012 Feb; 44(2):307-12. doi: 10.1007/s11250-011-0021-0. [PMID: 22105907]
  • Xin-Yuan Ding, Cheng-Jiao Hong, Yang Liu, Zong-Lin Gu, Kong-Lang Xing, Ai-Jun Zhu, Wei-Liang Chen, Lin-Seng Shi, Xue-Nong Zhang, Qiang Zhang. Pharmacokinetics, tissue distribution, and metabolites of a polyvinylpyrrolidone-coated norcantharidin chitosan nanoparticle formulation in rats and mice, using LC-MS/MS. International journal of nanomedicine. 2012; 7(?):1723-35. doi: 10.2147/ijn.s29696. [PMID: 22619523]
  • Xuelan Chen, Hengyi Xu, Weihua Lai, Yuan Chen, Xiaohui Yang, Yonghua Xiong. A sensitive chromatographic strip test for the rapid detection of enrofloxacin in chicken muscle. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment. 2012; 29(3):383-91. doi: 10.1080/19440049.2011.641509. [PMID: 22243423]
  • Kalliopi C Skyrianou, Franc Perdih, Athanasios N Papadopoulos, Iztok Turel, Dimitris P Kessissoglou, George Psomas. Nickel-quinolones interaction. Part 5-Biological evaluation of nickel(II) complexes with first-, second- and third-generation quinolones. Journal of inorganic biochemistry. 2011 Oct; 105(10):1273-85. doi: 10.1016/j.jinorgbio.2011.06.005. [PMID: 21820989]
  • María Ramos Payán, Miguel Ángel Bello López, Rut Fernández-Torres, Juan Antonio Ocaña González, Manuel Callejón Mochón. Hollow fiber-based liquid phase microextraction (HF-LPME) as a new approach for the HPLC determination of fluoroquinolones in biological and environmental matrices. Journal of pharmaceutical and biomedical analysis. 2011 May; 55(2):332-41. doi: 10.1016/j.jpba.2011.01.037. [PMID: 21353435]
  • M P Hermo, E Nemutlu, J Barbosa, D Barrón. Multiresidue determination of quinolones regulated by the European Union in bovine and porcine plasma. Application of chromatographic and capillary electrophoretic methodologies. Biomedical chromatography : BMC. 2011 May; 25(5):555-69. doi: 10.1002/bmc.1483. [PMID: 20641008]
  • Ayman Goudah, Sherifa Hasabelnaby. Disposition kinetics of levofloxacin in sheep after intravenous and intramuscular administration. Veterinary medicine international. 2010 Nov; 2010(?):727231. doi: 10.4061/2010/727231. [PMID: 21052556]
  • N Klamerth, S Malato, M I Maldonado, A Agüera, A R Fernández-Alba. Application of photo-fenton as a tertiary treatment of emerging contaminants in municipal wastewater. Environmental science & technology. 2010 Mar; 44(5):1792-8. doi: 10.1021/es903455p. [PMID: 20131796]
  • N Klamerth, L Rizzo, S Malato, Manuel I Maldonado, A Agüera, A R Fernández-Alba. Degradation of fifteen emerging contaminants at microg L(-1) initial concentrations by mild solar photo-Fenton in MWTP effluents. Water research. 2010 Jan; 44(2):545-54. doi: 10.1016/j.watres.2009.09.059. [PMID: 19853272]
  • John Mitchell. Small molecule immunosensing using surface plasmon resonance. Sensors (Basel, Switzerland). 2010; 10(8):7323-46. doi: 10.3390/s100807323. [PMID: 22163605]
  • Hervé Pouliquen, Raphaël Delépée, Chantal Thorin, Jacques Haury, Michaëlle Larhantec-Verdier, Marie-Line Morvan, Hervé Le Bris. Comparison of water, sediment, and plants for the monitoring of antibiotics: a case study on a river dedicated to fish farming. Environmental toxicology and chemistry. 2009 Mar; 28(3):496-502. doi: 10.1897/08-238.1. [PMID: 18980393]
  • Tao Ding, Dongxu Shen, Jinzhong Xu, Bin Wu, Huilan Chen, Chongyu Shen, Weijian Shen, Zengyun Zhao, Hongzhen Lian. [Simultaneous determination of 19 quinolone residues in honey using high performance liquid chromatography-tandem mass spectrometry]. Se pu = Chinese journal of chromatography. 2009 Jan; 27(1):34-8. doi: ". [PMID: 19449537]
  • A A M Stolker, P Rutgers, E Oosterink, J J P Lasaroms, R J B Peters, J A van Rhijn, M W F Nielen. Comprehensive screening and quantification of veterinary drugs in milk using UPLC-ToF-MS. Analytical and bioanalytical chemistry. 2008 Jul; 391(6):2309-22. doi: 10.1007/s00216-008-2168-8. [PMID: 18491081]
  • A Anadón, M A Martínez, M Martínez, C De La Cruz, M J Díaz, M R Martínez-Larrañaga. Oral bioavailability, tissue distribution and depletion of flumequine in the food producing animal, chicken for fattening. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2008 Feb; 46(2):662-70. doi: 10.1016/j.fct.2007.09.086. [PMID: 17950971]
  • Eleni A Christodoulou, Victoria F Samanidou, Ioannis N Papadoyannis. Development of an HPLC multi-residue method for the determination of ten quinolones in bovine liver and porcine kidney according to the European Union Decision 2002/657/EC. Journal of separation science. 2008 Jan; 31(1):119-27. doi: 10.1002/jssc.200700297. [PMID: 18081209]
  • M K Hassouan, O Ballesteros, A Zafra, J L Vílchez, A Navalón. Multiresidue method for simultaneous determination of quinolone antibacterials in pig kidney samples by liquid chromatography with fluorescence detection. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2007 Nov; 859(2):282-8. doi: 10.1016/j.jchromb.2007.10.002. [PMID: 17951118]
  • Florentina Cañada-Cañada, Anunciación Espinosa-Mansilla, Arsenio Muñoz de la Peña. Separation of fifteen quinolones by high performance liquid chromatography: application to pharmaceuticals and ofloxacin determination in urine. Journal of separation science. 2007 Jun; 30(9):1242-9. doi: 10.1002/jssc.200600536. [PMID: 17623463]
  • Willem Haasnoot, Hüsniye Gerçek, Geert Cazemier, Michel W F Nielen. Biosensor immunoassay for flumequine in broiler serum and muscle. Analytica chimica acta. 2007 Mar; 586(1-2):312-8. doi: 10.1016/j.aca.2006.10.003. [PMID: 17386729]
  • Francesco Barbato, Giuseppina di Martino, Lucia Grumetto, Maria Immacolata La Rotonda. Retention of quinolones on human serum albumin and alpha1-acid glycoprotein HPLC columns: relationships with different scales of lipophilicity. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2007 Mar; 30(3-4):211-9. doi: 10.1016/j.ejps.2006.11.004. [PMID: 17169537]
  • Anne-Catherine Huet, Caroline Charlier, Sheryl A Tittlemier, Gurmit Singh, Samuel Benrejeb, Philippe Delahaut. Simultaneous determination of (fluoro)quinolone antibiotics in kidney, marine products, eggs, and muscle by enzyme-linked immunosorbent assay (ELISA). Journal of agricultural and food chemistry. 2006 Apr; 54(8):2822-7. doi: 10.1021/jf052445i. [PMID: 16608195]
  • H Cantwell, M O'Keeffe. Evaluation of the Premi Test and comparison with the One-Plate Test for the detection of antimicrobials in kidney. Food additives and contaminants. 2006 Feb; 23(2):120-5. doi: 10.1080/02652030500357433. [PMID: 16449053]
  • Frode Todnem Vik-Mo, Oivind Bergh, Ole Bent Samuelsen. Efficacy of orally administered flumequine in the treatment of vibriosis caused by Listonella anguillarum in atlantic cod Gadus morhua. Diseases of aquatic organisms. 2005 Nov; 67(1-2):87-92. doi: 10.3354/dao067087. [PMID: 16385813]
  • R Villa, P Cagnardi, O Sonzogni, S Carli. Flumequine in the goat: pharmacokinetics after intravenous and intramuscular administration. Veterinary research communications. 2005 Nov; 29(8):689-98. doi: 10.1007/s11259-005-3867-7. [PMID: 16369883]
  • Eric Verdon, Pierrick Couedor, Brigitte Roudaut, Pascal Sandérs. Multiresidue method for simultaneous determination of ten quinolone antibacterial residues in multimatrix/multispecies animal tissues by liquid chromatography with fluorescence detection: single laboratory validation study. Journal of AOAC International. 2005 Jul; 88(4):1179-92. doi: . [PMID: 16156083]
  • R Villa, P Cagnardi, F Acocella, P Massi, P Anfossi, F Asta, S Carli. Pharmacodynamics and pharmacokinetics of flumequine in pigs after single intravenous and intramuscular administration. Veterinary journal (London, England : 1997). 2005 Jul; 170(1):101-7. doi: 10.1016/j.tvjl.2004.05.012. [PMID: 15993793]
  • C Belloc, D N Lam, J-L Pellerin, F Beaudeau, A Laval. Effect of quinolone treatment on selection and persistence of quinolone-resistant Escherichia coli in swine faecal flora. Journal of applied microbiology. 2005; 99(4):954-9. doi: 10.1111/j.1365-2672.2005.02667.x. [PMID: 16162248]
  • Els Van Coillie, Jan De Block, Wim Reybroeck. Development of an indirect competitive ELISA for flumequine residues in raw milk using chicken egg yolk antibodies. Journal of agricultural and food chemistry. 2004 Aug; 52(16):4975-8. doi: 10.1021/jf049593d. [PMID: 15291461]
  • Raphaël Delépée, Hervé Pouliquen, Hervé Le Bris. The bryophyte Fontinalis antipyretica Hedw. bioaccumulates oxytetracycline, flumequine and oxolinic acid in the freshwater environment. The Science of the total environment. 2004 Apr; 322(1-3):243-53. doi: 10.1016/j.scitotenv.2003.09.018. [PMID: 15081752]
  • ". Evaluation of certain veterinary drug residues in food. Sixty-second report of the Joint FAO/WHO Expert Committee on food additives. World Health Organization technical report series. 2004; 925(?):1-72. doi: ". [PMID: 15587045]
  • George Rigos, Athanassios E Tyrpenou, Ioannis Nengas, Maria Yiagnisis, Maria Koutsodimou, Maria Alexis, Gera M Troisi. Pharmacokinetics of flumequine and in vitro activity against bacterial pathogens of gilthead sea bream Sparus aurata. Diseases of aquatic organisms. 2003 Mar; 54(1):35-41. doi: 10.3354/dao054035. [PMID: 12718468]
  • B Toussaint, G Bordin, A Janosi, A R Rodriguez. Validation of a liquid chromatography-tandem mass spectrometry method for the simultaneous quantification of 11 (fluoro)quinolone antibiotics in swine kidney. Journal of chromatography. A. 2002 Nov; 976(1-2):195-206. doi: 10.1016/s0021-9673(02)00948-2. [PMID: 12462610]
  • Margarita Hernández, Carme Aguilar, Francesc Borrull, Marta Calull. Determination of ciprofloxacin, enrofloxacin and flumequine in pig plasma samples by capillary isotachophoresis--capillary zone electrophoresis. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2002 May; 772(1):163-72. doi: 10.1016/s1570-0232(02)00071-5. [PMID: 12016028]
  • Géry van Vyncht, Amaya Jànosi, Guy Bordin, Brigitte Toussaint, Guy Maghuin-Rogister, Edwin De Pauw, Adela Rosa Rodriguez. Multiresidue determination of (fluoro)quinolone antibiotics in swine kidney using liquid chromatography-tandem mass spectrometry. Journal of chromatography. A. 2002 Apr; 952(1-2):121-9. doi: 10.1016/s0021-9673(02)00092-4. [PMID: 12064523]
  • Margarita Hernández, Francesc Borrull, Marta Calull. Using nonaqueous capillary electrophoresis to analyze several quinolones in pig kidney samples. Electrophoresis. 2002 Feb; 23(3):506-11. doi: 10.1002/1522-2683(200202)23:3<506::aid-elps506>3.0.co;2-c. [PMID: 11870754]
  • M K Hansen, K Ingebrigtsen, W L Hayton, T E Horsberg. Disposition of 14C-flumequine in eel Anguilla anguilla, turbot Scophthalmus maximus and halibut Hippoglossus hippoglossus after oral and intravenous administration. Diseases of aquatic organisms. 2001 Dec; 47(3):183-91. doi: 10.3354/dao047183. [PMID: 11804417]
  • O B Samuelsen, A Ervik. Absorption, tissue distribution and excretion of flumequine and oxolinic acid in corkwing wrasse (Symphodus melops) following a single intraperitoneal injection or bath treatment. Journal of veterinary pharmacology and therapeutics. 2001 Apr; 24(2):111-6. doi: 10.1046/j.1365-2885.2001.00319.x. [PMID: 11442785]
  • M K Hansen, T E Horsberg. Single-dose pharmacokinetics of flumequine in the eel (Anguilla anguilla) after intravascular, oral and bath administration. Journal of veterinary pharmacology and therapeutics. 2000 Jun; 23(3):169-74. doi: 10.1046/j.1365-2885.2000.00277.x. [PMID: 11110105]
  • M K Hansen, T E Horsberg. Single-dose pharmacokinetics of flumequine in cod (Gadus morhua) and goldsinny wrasse (Ctenolabrus rupestris). Journal of veterinary pharmacology and therapeutics. 2000 Jun; 23(3):163-8. doi: 10.1046/j.1365-2885.2000.00259.x. [PMID: 11110104]
  • L Migliore, S Cozzolino, M Fiori. Phytotoxicity to and uptake of flumequine used in intensive aquaculture on the aquatic weed, Lythrum salicaria L. Chemosphere. 2000 Apr; 40(7):741-50. doi: 10.1016/s0045-6535(99)00448-8. [PMID: 10705552]
  • A Ruiz-García, M Bermejo, V Merino, G Sánchez-Castaño, J Freixas, T M Garrigues. Pharmacokinetics, bioavailability and absorption of flumequine in the rat. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 1999 Nov; 48(3):253-8. doi: 10.1016/s0939-6411(99)00057-0. [PMID: 10612037]
  • P J van der Wolf, J H Bongers, A R Elbers, F M Franssen, W A Hunneman, A C van Exsel, M J Tielen. Salmonella infections in finishing pigs in The Netherlands: bacteriological herd prevalence, serogroup and antibiotic resistance of isolates and risk factors for infection. Veterinary microbiology. 1999 Jul; 67(4):263-75. doi: 10.1016/s0378-1135(99)00054-1. [PMID: 10466502]
  • O B Samuelsen, B Hjeltnes, L Torkildsen. Efficacy of orally administered oxolinic acid and Vetoquinol, an oxolinic acid ester, for the treatment of furunculosis in Atlantic salmon Salmo salar held in seawater. Diseases of aquatic organisms. 1999 Jun; 37(1):53-9. doi: 10.3354/dao037053. [PMID: 10439903]
  • S M Plakas, K R el Said, F A Bencsath, S M Musser, C C Walker. Determination of flumequine in channel catfish by liquid chromatography with fluorescence detection. Journal of AOAC International. 1999 May; 82(3):614-9. doi: 10.1093/jaoac/82.3.614. [PMID: 10367379]
  • M K Hansen, T E Horsberg. Single-dose pharmacokinetics of flumequine in halibut (Hippoglossus hippoglossus) and turbot (Scophthalmus maximus). Journal of veterinary pharmacology and therapeutics. 1999 Apr; 22(2):122-6. doi: 10.1046/j.1365-2885.1999.00191.x. [PMID: 10372596]
  • S Sohlberg, B Martinsen, T E Horsberg, N E Søli. Excretion of flumequine in free-swimming Atlantic salmon (Salmo salar), determined by cannulation of the dorsal aorta, gall bladder and urethra. Journal of veterinary pharmacology and therapeutics. 1999 Feb; 22(1):72-5. doi: 10.1046/j.1365-2885.1999.00179.x. [PMID: 10211722]
  • J M Delmas, A M Chapel, P Sanders. Determination of flumequine and 7-hydroxyflumequine in plasma of sheep by high-performance liquid chromatography. Journal of chromatography. B, Biomedical sciences and applications. 1998 Aug; 712(1-2):263-8. doi: 10.1016/s0378-4347(98)00159-5. [PMID: 9698250]
  • S Besse, J Guyonnet, P Delatour. Quantification of flumequine enantiomers in plasma by high-performance liquid chromatography. Journal of veterinary pharmacology and therapeutics. 1998 Aug; 21(4):330-2. doi: 10.1046/j.1365-2885.1998.00145.x. [PMID: 9731957]
  • J M Delmas, A M Chapel, P Sanders. Determination of residues of flumequine and 7-hydroxyflumequine in edible sheep tissues by liquid chromatography with fluorimetric and ultraviolet detection. Journal of AOAC International. 1998 May; 81(3):519-27. doi: 10.1093/jaoac/81.3.519. [PMID: 9606916]
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  • S Sohlberg, B Martinsen, T E Horsberg, N E Søli. Evaluation of the dorsal aorta cannulation technique for pharmacokinetic studies in Atlantic salmon (Salmo salar) in sea water. Journal of veterinary pharmacology and therapeutics. 1996 Dec; 19(6):460-5. doi: 10.1111/j.1365-2885.1996.tb00083.x. [PMID: 8971675]
  • J Guyonnet, M Pacaud, M Richard, A Doisi, F Spavone, P Hellings. Routine determination of flumequine in kidney tissue of pig using automated liquid chromatography. Journal of chromatography. B, Biomedical applications. 1996 Apr; 679(1-2):177-84. doi: 10.1016/0378-4347(95)00582-x. [PMID: 8998558]
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  • T B Vree, U M Hoeben, E W van Ewijk-Beneken Kolmer, J F Nouws. Glucuronidation of flumequine by the turtle Pseudemys scripta elegans. Journal of veterinary pharmacology and therapeutics. 1994 Feb; 17(1):80-2. doi: 10.1111/j.1365-2885.1994.tb00527.x. [PMID: 8196100]
  • B Lacarelle, O Blin, C Audebert, P Auquier, H Karsenty, F Horriere, A Durand. The quinolone, flumequine, has no effect on theophylline pharmacokinetics. European journal of clinical pharmacology. 1994; 46(5):477-8. doi: 10.1007/bf00191915. [PMID: 7957547]
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