Dihydrofolic acid (BioDeep_00000001333)
Secondary id: BioDeep_00000413236, BioDeep_00001868416
human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite Chemicals and Drugs
代谢物信息卡片
(2S)-2-[(4-{[(2-amino-4-oxo-1,4,7,8-tetrahydropteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid
化学式: C19H21N7O6 (443.15532460000003)
中文名称: 二氢叶酸, 二氢叶酸
谱图信息:
最多检出来源 Viridiplantae(plant) 0.04%
分子结构信息
SMILES: C1C(=NC2=C(N1)N=C(NC2=O)N)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O
InChI: InChI=1S/C19H21N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,12,21H,5-8H2,(H,24,29)(H,27,28)(H,31,32)(H4,20,22,25,26,30)
描述信息
Dihydrofolic acid is a folic acid derivative acted upon by dihydrofolate reductase to produce tetrahydrofolic acid. It interacts with bacteria during cell division. It can be targeted with drug analogs to prevent nucleic acid synthesis. Dihydrofolic acid is also known by the name Dihydrofolate - more commonly Vitamin B9. [HMDB]
Dihydrofolic acid is a folic acid derivative acted upon by dihydrofolate reductase to produce tetrahydrofolic acid. It interacts with bacteria during cell division. It can be targeted with drug analogs to prevent nucleic acid synthesis. Dihydrofolic acid is also known by the name Dihydrofolate - more commonly Vitamin B9.
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Dihydrofolic acid is a folic acid derivative acted upon by dihydrofolate reductase to produce tetrahydrofolic acid.
同义名列表
24 个代谢物同义名
(2S)-2-[(4-{[(2-amino-4-oxo-1,4,7,8-tetrahydropteridin-6-yl)methyl]amino}phenyl)formamido]pentanedioic acid; 2-(4-(((2-Amino-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)methyl)amino)benzamido)pentanedioic acid; N-[4-[[(2-Amino-3,4,7,8-tetrahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid; N-[4-[[(2-Amino-1,4,7,8-tetrahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid; N-(4-(((2-Amino-1,4,7,8-tetrahydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid; N-(4-{[(2-amino-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid; L-N-[p-[[(2-Amino-7,8-dihydro-4-hydroxy-6-pteridinyl)methyl]amino]benzoyl]-glutamic acid; N-(7,8-Dihydropteroyl)-L-glutamic acid; 7,8-Dihydropteroyl-L-glutamic acid; N-(7,8-Dihydropteroyl)-L-glutamate; 7,8-Dihydropteroylglutamic acid; Dihydropteroyl-L-glutamic acid; 7,8-Dihydropteroylglutamate; Dihydrofolate, (D)-isomer; 7,8-Dihydro-L-folic acid; 7,8-Dihydrofolic acid; 7,8-Dihydrofolate; Dihydrofolic acid; Dihydrofolate; Vitamin B9; H2PteGlu1; H2PteGlu; FAH2; Dihydrofolic acid
数据库引用编号
25 个数据库交叉引用编号
- ChEBI: CHEBI:182629
- ChEBI: CHEBI:15633
- KEGG: C00415
- PubChem: 135402025
- PubChem: 135398604
- PubChem: 98792
- HMDB: HMDB0001056
- Metlin: METLIN3537
- DrugBank: DB02015
- ChEMBL: CHEMBL1371525
- ChEMBL: CHEMBL46294
- Wikipedia: Dihydrofolic acid
- MetaCyc: DIHYDROFOLATE
- KNApSAcK: C00007248
- foodb: FDB022395
- chemspider: 89228
- CAS: 42572-30-5
- CAS: 4033-27-6
- PMhub: MS000000345
- PubChem: 3705
- PDB-CCD: DHF
- 3DMET: B01240
- NIKKAJI: J373.767E
- RefMet: Dihydrofolic acid
- medchemexpress: HY-113267
分类词条
相关代谢途径
Reactome(0)
BioCyc(5)
代谢反应
1150 个相关的代谢反应过程信息。
Reactome(12)
- Metabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - Nucleotide metabolism:
H2O + XTP ⟶ PPi + XMP - Interconversion of nucleotide di- and triphosphates:
AMP + ATP ⟶ ADP - Metabolism:
2MACA-CoA + CoA ⟶ Ac-CoA + PROP-CoA - Nucleotide metabolism:
H2O + XTP ⟶ PPi + XMP - Interconversion of nucleotide di- and triphosphates:
AMP + ATP ⟶ ADP - Metabolism:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA - Nucleotide metabolism:
H2O + XTP ⟶ PPi + XMP - Interconversion of nucleotide di- and triphosphates:
AMP + ATP ⟶ ADP - Metabolism of vitamins and cofactors:
H2O + Oxygen + PXL ⟶ H2O2 + PDXate - Metabolism of water-soluble vitamins and cofactors:
H2O + Oxygen + PXL ⟶ H2O2 + PDXate - Metabolism of folate and pterines:
FOLA + Homologues of FOLR2 ⟶ FOLR2:FOLA
BioCyc(12)
- folate metabolism:
H+ + ser + tetrahydrofolate ⟶ 5,10-methylene-THF + H2O + gly - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dCTP ⟶ ammonia + dUTP - purine and pyrimidine metabolism:
adenosine + phosphate ⟶ α-D-ribose-1-phosphate + adenine - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dCTP ⟶ ammonia + dUTP - formylTHF biosynthesis II:
H+ + NAD+ + gly + tetrahydrofolate ⟶ 5,10-methylenetetrahydrofolate + CO2 + NADH + ammonia - formylTHF biosynthesis I:
H+ + NAD+ + gly + tetrahydrofolate ⟶ 5,10-methylenetetrahydrofolate + CO2 + NADH + ammonia - formylTHF biosynthesis I:
H+ + NAD+ + gly + tetrahydrofolate ⟶ 5,10-methylenetetrahydrofolate + CO2 + NADH + ammonia - formylTHF biosynthesis II:
H+ + NAD+ + gly + tetrahydrofolate ⟶ 5,10-methylenetetrahydrofolate + CO2 + NADH + ammonia - tetrahydrofolate biosynthesis:
7,8-dihydropteroate + ATP + glt ⟶ 7,8-dihydrofolate + ADP + H+ + phosphate - formylTHF biosynthesis I:
H+ + NAD+ + gly + tetrahydrofolate ⟶ 5,10-methylenetetrahydrofolate + CO2 + NADH + ammonia - tetrahydrofolate biosynthesis II:
ATP + glt + tetrahydrofolate ⟶ ADP + H+ + phosphate + tetrahydrofolate-L-glutamate - tetrahydrofolate biosynthesis I:
6-hydroxymethyl-7,8-dihydropterin + ATP ⟶ 6-hydroxymethyl-dihydropterin diphosphate + AMP + H+
WikiPathways(6)
- Fluoropyrimidine activity:
Capecitabine ⟶ 5-dFCR - Ethanol effects on histone modifications:
Ethanol ⟶ Acetaldehyde - Folate metabolism:
Thromboxane A2 ⟶ Thromboxane B2 - Fluoropyrimidine activity:
Capecitabine ⟶ 5-dFCR - Folate metabolism:
Thromboxane A2 ⟶ Thromboxane B2 - Disorders of folate metabolism and transport:
Folic acid ⟶ DHF
Plant Reactome(320)
- Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
9-mercaptodethiobiotin ⟶ Btn - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
L-Glu + imidazole acetol-phosphate ⟶ 2OG + L-histidinol-phosphate - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
5,10-methylene-THF + H2O + KIV ⟶ 2-dehydropantoate + THF - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
DHF + H+ + TPNH ⟶ THF + TPN - Tetrahydrofolate biosynthesis II:
ADP + Pi + an N10-formyl-tetrahydrofolate ⟶ ATP + HCOOH + a tetrahydrofolate polyglutamate - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
5,10-methylene-THF + H2O + KIV ⟶ 2-dehydropantoate + THF - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
5,10-methylene-THF + H2O + KIV ⟶ 2-dehydropantoate + THF - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
5,10-methylene-THF + H2O + KIV ⟶ 2-dehydropantoate + THF - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
5,10-methylene-THF + H2O + KIV ⟶ 2-dehydropantoate + THF - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
5,10-methylene-THF + H2O + KIV ⟶ 2-dehydropantoate + THF - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
L-Glu + imidazole acetol-phosphate ⟶ 2OG + L-histidinol-phosphate - Cofactor biosyntheses:
5,10-methylene-THF + H2O + KIV ⟶ 2-dehydropantoate + THF - Folate biosynthesis:
DHF + H+ + TPNH ⟶ THF + TPN - Tetrahydrofolate biosynthesis II:
DHF + H+ + TPNH ⟶ THF + TPN - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
L-Glu + imidazole acetol-phosphate ⟶ 2OG + L-histidinol-phosphate - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
5,10-methylene-THF + H2O + KIV ⟶ 2-dehydropantoate + THF - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
5,10-methylene-THF + H2O + KIV ⟶ 2-dehydropantoate + THF - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
5,10-methylene-THF + H2O + KIV ⟶ 2-dehydropantoate + THF - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
FAD + PROP-CoA ⟶ FADH2 + acryloyl-CoA - Cofactor biosyntheses:
5,10-methylene-THF + H2O + KIV ⟶ 2-dehydropantoate + THF - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Metabolism and regulation:
CoA + NAD + methylmalonate-semialdehyde ⟶ NADH + PROP-CoA + carbon dioxide - Cofactor biosyntheses:
2OG + L-Val ⟶ KIV + L-Glu - Folate biosynthesis:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP - Tetrahydrofolate biosynthesis II:
6-hydroxymethyl-dihydropterin + ATP ⟶ 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + AMP
INOH(2)
- Folate metabolism ( Folate metabolism ):
6-Pyruvoyl-5,6,7,8-tetrahydro-pterin + NADPH ⟶ 5,6,7,8-Tetrahydro-biopterin + NADP+ - Pyrimidine Nucleotides and Nucleosides metabolism ( Pyrimidine Nucleotides and Nucleosides metabolism ):
Deoxy-cytidine + H2O ⟶ Deoxy-uridine + NH3
PlantCyc(760)
- superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis I:
a 5,10-methylenetetrahydrofolate + dUMP ⟶ a 7,8-dihydrofolate + dTMP - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
a 5,10-methylenetetrahydrofolate + dUMP ⟶ a 7,8-dihydrofolate + dTMP - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin 3'-phosphate + H2O ⟶ 7,8-dihydroneopterin + phosphate - superpathway of tetrahydrofolate biosynthesis:
7,8-dihydroneopterin 3'-phosphate + H2O ⟶ 7,8-dihydroneopterin + phosphate - tetrahydrofolate biosynthesis:
NADP+ + a tetrahydrofolate ⟶ H+ + NADPH + a 7,8-dihydrofolate - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
CTP + H+ + formate ⟶ CO2 + H2O + dCTP - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis II:
CTP + H+ + formate ⟶ CO2 + H2O + dCTP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
CTP + H+ + formate ⟶ CO2 + H2O + dCTP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis II:
CTP + H+ + formate ⟶ CO2 + H2O + dCTP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
CTP + H+ + formate ⟶ CO2 + H2O + dCTP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis II:
a 5,10-methylenetetrahydrofolate + dUMP ⟶ a 7,8-dihydrofolate + dTMP - superpathway of tetrahydrofolate biosynthesis:
7,8-dihydroneopterin 3'-phosphate + H2O ⟶ 7,8-dihydroneopterin + phosphate - tetrahydrofolate biosynthesis:
(7,8-dihydropterin-6-yl)methyl diphosphate + 4-aminobenzoate ⟶ 7,8-dihydropteroate + diphosphate - pyrimidine deoxyribonucleotides de novo biosynthesis I:
a 5,10-methylenetetrahydrofolate + dUMP ⟶ a 7,8-dihydrofolate + dTMP - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin 3'-phosphate + H2O ⟶ 7,8-dihydroneopterin + phosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis II:
CTP + H+ + formate ⟶ CO2 + H2O + dCTP - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
H2O + dUTP ⟶ H+ + dUMP + diphosphate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of tetrahydrofolate biosynthesis:
GTP + H2O ⟶ 7,8-dihydroneopterin 3'-triphosphate + H+ + formate - tetrahydrofolate biosynthesis I:
NADP+ + a tetrahydrofolate ⟶ H+ + NADPH + a 7,8-dihydrofolate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis I:
ATP + dTMP ⟶ ADP + dTDP - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis II:
CTP + H+ + formate ⟶ CO2 + H2O + dCTP - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis I:
a 5,10-methylenetetrahydrofolate + dUMP ⟶ a 7,8-dihydrofolate + dTMP - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis I:
ATP + dTMP ⟶ ADP + dTDP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
ATP + dTMP ⟶ ADP + dTDP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis I:
ATP + dTMP ⟶ ADP + dTDP - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis I:
a 5,10-methylenetetrahydrofolate + dUMP ⟶ a 7,8-dihydrofolate + dTMP - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
a 5,10-methylenetetrahydrofolate + dUMP ⟶ a 7,8-dihydrofolate + dTMP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
ATP + dTMP ⟶ ADP + dTDP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis I:
a 5,10-methylenetetrahydrofolate + dUMP ⟶ a 7,8-dihydrofolate + dTMP - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis I:
a 5,10-methylenetetrahydrofolate + dUMP ⟶ a 7,8-dihydrofolate + dTMP - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
ATP + dTMP ⟶ ADP + dTDP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
a 5,10-methylenetetrahydrofolate + dUMP ⟶ a 7,8-dihydrofolate + dTMP - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
ATP + dTMP ⟶ ADP + dTDP - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
a 5,10-methylenetetrahydrofolate + dUMP ⟶ a 7,8-dihydrofolate + dTMP - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis I:
a 5,10-methylenetetrahydrofolate + dUMP ⟶ a 7,8-dihydrofolate + dTMP - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis I:
a 5,10-methylenetetrahydrofolate + dUMP ⟶ a 7,8-dihydrofolate + dTMP - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
ATP + dTMP ⟶ ADP + dTDP - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis I:
ATP + dTMP ⟶ ADP + dTDP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis I:
a 5,10-methylenetetrahydrofolate + dUMP ⟶ a 7,8-dihydrofolate + dTMP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis I:
a 5,10-methylenetetrahydrofolate + dUMP ⟶ a 7,8-dihydrofolate + dTMP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
ATP + dTMP ⟶ ADP + dTDP - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis I:
ATP + dTMP ⟶ ADP + dTDP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis I:
a 5,10-methylenetetrahydrofolate + dUMP ⟶ a 7,8-dihydrofolate + dTMP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
a 5,10-methylenetetrahydrofolate + dUMP ⟶ a 7,8-dihydrofolate + dTMP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + a nucleoside triphosphate ⟶ H+ + a nucleoside diphosphate + dCMP - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + a nucleoside triphosphate ⟶ H+ + a nucleoside diphosphate + dCMP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
a 5,10-methylenetetrahydrofolate + dUMP ⟶ a 7,8-dihydrofolate + dTMP - pyrimidine deoxyribonucleotides de novo biosynthesis II:
a 5,10-methylenetetrahydrofolate + dUMP ⟶ a 7,8-dihydrofolate + dTMP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - pyrimidine deoxyribonucleotides de novo biosynthesis II:
CTP + H+ + formate ⟶ CO2 + H2O + dCTP - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis I:
ATP + dTMP ⟶ ADP + dTDP - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
a 5,10-methylenetetrahydrofolate + dUMP ⟶ a 7,8-dihydrofolate + dTMP - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - pyrimidine deoxyribonucleosides salvage:
2'-deoxyuridine + ATP ⟶ ADP + H+ + dUMP - pyrimidine deoxyribonucleotides de novo biosynthesis I:
ATP + dTMP ⟶ ADP + dTDP - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - pyrimidine deoxyribonucleotides de novo biosynthesis I:
a 5,10-methylenetetrahydrofolate + dUMP ⟶ a 7,8-dihydrofolate + dTMP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
(S)-dihydroorotate + an electron-transfer quinone ⟶ an electron-transfer quinol + orotate - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - tetrahydrofolate biosynthesis II:
7,8-dihydroneopterin ⟶ 6-(hydroxymethyl)-7,8-dihydropterin + glycolaldehyde - tetrahydrofolate biosynthesis II:
6-(hydroxymethyl)-7,8-dihydropterin + ATP ⟶ (7,8-dihydropterin-6-yl)methyl diphosphate + AMP + H+ - pyrimidine deoxyribonucleotides de novo biosynthesis II:
H+ + UTP + formate ⟶ CO2 + H2O + dUTP - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - pyrimidine deoxyribonucleotides de novo biosynthesis I:
ATP + dTMP ⟶ ADP + dTDP - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
diphosphate + orotidine 5'-phosphate ⟶ PRPP + orotate - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - dTMP de novo biosynthesis (mitochondrial):
NADP+ + a tetrahydrofolate ⟶ H+ + NADPH + a 7,8-dihydrofolate - dTMP de novo biosynthesis (mitochondrial):
NADP+ + a tetrahydrofolate ⟶ H+ + NADPH + a 7,8-dihydrofolate - dTMP de novo biosynthesis (mitochondrial):
NADP+ + a tetrahydrofolate ⟶ H+ + NADPH + a 7,8-dihydrofolate - dTMP de novo biosynthesis (mitochondrial):
NADP+ + a tetrahydrofolate ⟶ H+ + NADPH + a 7,8-dihydrofolate - dTMP de novo biosynthesis (mitochondrial):
NADP+ + a tetrahydrofolate ⟶ H+ + NADPH + a 7,8-dihydrofolate - dTMP de novo biosynthesis (mitochondrial):
NADP+ + a tetrahydrofolate ⟶ H+ + NADPH + a 7,8-dihydrofolate - dTMP de novo biosynthesis (mitochondrial):
NADP+ + a tetrahydrofolate ⟶ H+ + NADPH + a 7,8-dihydrofolate - pyrimidine deoxyribonucleotides biosynthesis from CTP:
H2O + dCDP ⟶ H+ + dCMP + phosphate - tetrahydrofolate biosynthesis II:
4-amino-4-deoxychorismate ⟶ 4-aminobenzoate + H+ + pyruvate - pyrimidine deoxyribonucleosides salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - superpathway of pyrimidine deoxyribonucleoside salvage:
2'-deoxycytidine + H+ + H2O ⟶ 2'-deoxyuridine + ammonium - tetrahydrofolate biosynthesis:
NADP+ + a tetrahydrofolate ⟶ H+ + NADPH + a 7,8-dihydrofolate - pyrimidine deoxyribonucleotides de novo biosynthesis I:
CTP + H2O ⟶ CDP + H+ + phosphate - superpathway of tetrahydrofolate biosynthesis:
4-amino-4-deoxychorismate ⟶ 4-aminobenzoate + H+ + pyruvate - dTMP de novo biosynthesis (mitochondrial):
NADP+ + a tetrahydrofolate ⟶ H+ + NADPH + a 7,8-dihydrofolate - dTMP de novo biosynthesis (mitochondrial):
NADP+ + a tetrahydrofolate ⟶ H+ + NADPH + a 7,8-dihydrofolate - dTMP de novo biosynthesis (mitochondrial):
NADP+ + a tetrahydrofolate ⟶ H+ + NADPH + a 7,8-dihydrofolate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
ATP + H2O + UTP + gln ⟶ ADP + CTP + H+ + glu + phosphate - dTMP de novo biosynthesis (mitochondrial):
NADP+ + a tetrahydrofolate ⟶ H+ + NADPH + a 7,8-dihydrofolate - dTMP de novo biosynthesis (mitochondrial):
NADP+ + a tetrahydrofolate ⟶ H+ + NADPH + a 7,8-dihydrofolate - dTMP de novo biosynthesis (mitochondrial):
NADP+ + a tetrahydrofolate ⟶ H+ + NADPH + a 7,8-dihydrofolate - dTMP de novo biosynthesis (mitochondrial):
NADP+ + a tetrahydrofolate ⟶ H+ + NADPH + a 7,8-dihydrofolate - dTMP de novo biosynthesis (mitochondrial):
NADP+ + a tetrahydrofolate ⟶ H+ + NADPH + a 7,8-dihydrofolate - dTMP de novo biosynthesis (mitochondrial):
NADP+ + a tetrahydrofolate ⟶ H+ + NADPH + a 7,8-dihydrofolate - dTMP de novo biosynthesis (mitochondrial):
NADP+ + a tetrahydrofolate ⟶ H+ + NADPH + a 7,8-dihydrofolate - dTMP de novo biosynthesis (mitochondrial):
NADP+ + a tetrahydrofolate ⟶ H+ + NADPH + a 7,8-dihydrofolate - dTMP de novo biosynthesis (mitochondrial):
NADP+ + a tetrahydrofolate ⟶ H+ + NADPH + a 7,8-dihydrofolate - dTMP de novo biosynthesis (mitochondrial):
NADP+ + a tetrahydrofolate ⟶ H+ + NADPH + a 7,8-dihydrofolate - dTMP de novo biosynthesis (mitochondrial):
NADP+ + a tetrahydrofolate ⟶ H+ + NADPH + a 7,8-dihydrofolate - dTMP de novo biosynthesis (mitochondrial):
NADP+ + a tetrahydrofolate ⟶ H+ + NADPH + a 7,8-dihydrofolate - dTMP de novo biosynthesis (mitochondrial):
NADP+ + a tetrahydrofolate ⟶ H+ + NADPH + a 7,8-dihydrofolate - dTMP de novo biosynthesis (mitochondrial):
NADP+ + a tetrahydrofolate ⟶ H+ + NADPH + a 7,8-dihydrofolate - superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis:
ATP + H2O + gln + hydrogencarbonate ⟶ ADP + H+ + carbamoyl phosphate + glu + phosphate
COVID-19 Disease Map(1)
- @COVID-19 Disease
Map["name"]:
2-Methyl-3-acetoacetyl-CoA + Coenzyme A ⟶ Acetyl-CoA + Propanoyl-CoA
PathBank(37)
- Pyrimidine Metabolism:
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine - beta-Ureidopropionase Deficiency:
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine - UMP Synthase Deficiency (Orotic Aciduria):
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine - Dihydropyrimidinase Deficiency:
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine - MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy):
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine - Pyrimidine Metabolism:
Hydrogen Ion + N-carbamoyl-L-aspartate ⟶ 4,5-Dihydroorotic acid + Water - One Carbon Pool by Folate:
S-Aminomethyldihydrolipoylprotein; + Tetrahydrofolic acid ⟶ 5,10-Methylene-THF + Ammonia + dihydrolipoylprotein - One Carbon Pool by Folate I:
S-Aminomethyldihydrolipoylprotein; + Tetrahydrofolic acid ⟶ 5,10-Methylene-THF + Ammonia + dihydrolipoylprotein - Pyrimidine Metabolism:
Hydrogen Ion + N-carbamoyl-L-aspartate ⟶ 4,5-Dihydroorotic acid + Water - Pyrimidine Metabolism:
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine - beta-Ureidopropionase Deficiency:
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine - Dihydropyrimidinase Deficiency:
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine - UMP Synthase Deficiency (Orotic Aciduria):
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine - MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy):
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine - Pyrimidine Metabolism:
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine - Pyrimidine Metabolism:
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine - Pyrimidine Metabolism:
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine - Pyrimidine Metabolism:
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine - beta-Ureidopropionase Deficiency:
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine - Dihydropyrimidinase Deficiency:
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine - UMP Synthase Deficiency (Orotic Aciduria):
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine - MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy):
Deoxycytidine + Water ⟶ Ammonia + Deoxyuridine - Pyrimidine Metabolism:
Hydrogen Ion + N-carbamoyl-L-aspartate ⟶ 4,5-Dihydroorotic acid + Water - One Carbon Pool by Folate:
S-Aminomethyldihydrolipoylprotein; + Tetrahydrofolic acid ⟶ 5,10-Methylene-THF + Ammonia + dihydrolipoylprotein - Folate Metabolism:
5-Formiminotetrahydrofolic acid ⟶ 5,10-Methenyltetrahydrofolic acid + Ammonia - Methotrexate Action Pathway:
5-Formiminotetrahydrofolic acid ⟶ 5,10-Methenyltetrahydrofolic acid + Ammonia - Methylenetetrahydrofolate Reductase Deficiency (MTHFRD):
5-Formiminotetrahydrofolic acid ⟶ 5,10-Methenyltetrahydrofolic acid + Ammonia - Folate Malabsorption, Hereditary:
5-Formiminotetrahydrofolic acid ⟶ 5,10-Methenyltetrahydrofolic acid + Ammonia - Folate Metabolism:
5-Formiminotetrahydrofolic acid ⟶ 5,10-Methenyltetrahydrofolic acid + Ammonia - Folate Malabsorption, Hereditary:
5-Formiminotetrahydrofolic acid ⟶ 5,10-Methenyltetrahydrofolic acid + Ammonia - Methylenetetrahydrofolate Reductase Deficiency (MTHFRD):
5-Formiminotetrahydrofolic acid ⟶ 5,10-Methenyltetrahydrofolic acid + Ammonia - Folate Malabsorption, Hereditary:
5-Formiminotetrahydrofolic acid ⟶ 5,10-Methenyltetrahydrofolic acid + Ammonia - Folate Metabolism:
5-Formiminotetrahydrofolic acid ⟶ 5,10-Methenyltetrahydrofolic acid + Ammonia - Folate Metabolism:
5-Formiminotetrahydrofolic acid ⟶ 5,10-Methenyltetrahydrofolic acid + Ammonia - Folate Metabolism:
5-Formiminotetrahydrofolic acid ⟶ 5,10-Methenyltetrahydrofolic acid + Ammonia - Folate Metabolism:
5-Formiminotetrahydrofolic acid ⟶ 5,10-Methenyltetrahydrofolic acid + Ammonia - Methylenetetrahydrofolate Reductase Deficiency (MTHFRD):
5-Formiminotetrahydrofolic acid ⟶ 5,10-Methenyltetrahydrofolic acid + Ammonia
PharmGKB(0)
5 个相关的物种来源信息
- 9606 Homo sapiens: 10.1007/S11306-016-1051-4
- 3702 Arabidopsis thaliana: 10.1111/TPJ.14594
- 9606 Homo sapiens: 10.1007/S11306-016-1051-4
- 3702 Arabidopsis thaliana: 10.1111/TPJ.14594
- 9606 Homo sapiens: -
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Bharadwaja Vadloori, A K Sharath, N Prakash Prabhu, Radheshyam Maurya. Homology modelling, molecular docking, and molecular dynamics simulations reveal the inhibition of Leishmania donovani dihydrofolate reductase-thymidylate synthase enzyme by Withaferin-A.
BMC research notes.
2018 Apr; 11(1):246. doi:
10.1186/s13104-018-3354-1. [PMID: 29661206] - Mohamed Badr, Christian Kopp, Sandra Theison, Jennifer Meyer, Wolfgang E Trommer. Methotrexate-gelonin conjugate - an inhibitor of MCF-7 cells expressing the dihydrofolate receptor.
Biological chemistry.
2014 Dec; 395(12):1461-6. doi:
10.1515/hsz-2013-0270. [PMID: 25205711] - Sandy Shuo Zhao, Mathilde A Bichelberger, Damien Y Colin, Robert Robitaille, Joelle N Pelletier, Jean-François Masson. Monitoring methotrexate in clinical samples from cancer patients during chemotherapy with a LSPR-based competitive sensor.
The Analyst.
2012 Oct; 137(20):4742-50. doi:
10.1039/c2an35839e. [PMID: 22943049] - M Joerger, A D R Huitema, G Illerhaus, A J M Ferreri. Rational administration schedule for high-dose methotrexate in patients with primary central nervous system lymphoma.
Leukemia & lymphoma.
2012 Oct; 53(10):1867-75. doi:
10.3109/10428194.2012.676177. [PMID: 22530664] - Thommey P Thomas, Baohua Huang, Seok Ki Choi, Justin E Silpe, Alina Kotlyar, Ankur M Desai, Hong Zong, Jeremy Gam, Melvin Joice, James R Baker. Polyvalent dendrimer-methotrexate as a folate receptor-targeted cancer therapeutic.
Molecular pharmaceutics.
2012 Sep; 9(9):2669-2676. doi:
10.1021/mp3002232. [PMID: 22827500] - Susanne H Kirsch, Wolfgang Herrmann, Jürgen Geisel, Rima Obeid. Assay of whole blood (6S)-5-CH3-H4folate using ultra performance liquid chromatography tandem mass spectrometry.
Analytical and bioanalytical chemistry.
2012 Aug; 404(3):895-902. doi:
10.1007/s00216-012-6180-7. [PMID: 22729356] - Valentina Citton, Alberto Burlina, Claudio Baracchini, Massimo Gallucci, Alessia Catalucci, Sandro Dal Pos, Alessandro Burlina, Renzo Manara. Apparent diffusion coefficient restriction in the white matter: going beyond acute brain territorial ischemia.
Insights into imaging.
2012 Apr; 3(2):155-64. doi:
10.1007/s13244-011-0114-3. [PMID: 22696041] - Ann Sarah Koshy, S Jaya Kumari, Vageesh Ayyar, Prasanna Kumar. Evaluation of serum vitamin B12 levels in type 1 diabetics attending a tertiary care hospital: A preliminary cross - sectional study.
Indian journal of endocrinology and metabolism.
2012 Mar; 16 Suppl 1(?):S79-82. doi:
10.4103/2230-8210.94270. [PMID: 22701852] - Anastasia Malek, Luz-Elena Núñez, Marco Magistri, Lara Brambilla, Sandra Jovic, Giuseppina M Carbone, Francisco Morís, Carlo V Catapano. Modulation of the activity of Sp transcription factors by mithramycin analogues as a new strategy for treatment of metastatic prostate cancer.
PloS one.
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Acta naturae.
2012 Jan; 4(1):93-100. doi:
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PloS one.
2012; 7(4):e36192. doi:
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PLoS pathogens.
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Frontiers in plant science.
2012; 3(?):48. doi:
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PloS one.
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PloS one.
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Journal of experimental botany.
2012 Jan; 63(1):403-11. doi:
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Viruses.
2012 01; 4(1):28-61. doi:
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Frontiers in microbiology.
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Journal of tropical medicine.
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The Journal of biological chemistry.
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2011 Dec; 13(6):590-607. doi:
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Journal of clinical neurology (Seoul, Korea).
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BMC medical genetics.
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Diabetes.
2011 Oct; 60(10):2608-16. doi:
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Journal of medical case reports.
2011 Aug; 5(?):413. doi:
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Toxicology letters.
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Journal of experimental botany.
2011 Jul; 62(11):3781-98. doi:
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BMC genomics.
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The Journal of biological chemistry.
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Canadian journal of microbiology.
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Annals of clinical microbiology and antimicrobials.
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Plant physiology.
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PloS one.
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PloS one.
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European journal of histochemistry : EJH.
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BMC medicine.
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Clinical ophthalmology (Auckland, N.Z.).
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Nutrients.
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European journal of immunology.
2011 Jan; 41(1):214-23. doi:
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Iranian journal of kidney diseases.
2011 Jan; 5(1):45-9. doi:
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PloS one.
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Frontiers in plant science.
2011; 2(?):101. doi:
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Evidence-based complementary and alternative medicine : eCAM.
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International journal of molecular sciences.
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Journal of the American Veterinary Medical Association.
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PLoS computational biology.
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Drug testing and analysis.
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Journal of proteome research.
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Clinical pharmacokinetics.
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European journal of clinical pharmacology.
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Environmental research.
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Cancer chemotherapy and pharmacology.
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Sao Paulo medical journal = Revista paulista de medicina.
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International journal of oncology.
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PLoS genetics.
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Journal of proteome research.
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Malaria journal.
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Clinical and vaccine immunology : CVI.
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BMC microbiology.
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Neuropsychiatric disease and treatment.
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BMC cell biology.
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The Journal of biological chemistry.
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Poultry science.
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Molecular and biochemical parasitology.
2009 Nov; 168(1):74-83. doi:
10.1016/j.molbiopara.2009.06.011. [PMID: 19591883] - Roberta Alfieri, Matteo Barberis, Ferdinando Chiaradonna, Daniela Gaglio, Luciano Milanesi, Marco Vanoni, Edda Klipp, Lilia Alberghina. Towards a systems biology approach to mammalian cell cycle: modeling the entrance into S phase of quiescent fibroblasts after serum stimulation.
BMC bioinformatics.
2009 Oct; 10 Suppl 12(?):S16. doi:
10.1186/1471-2105-10-s12-s16. [PMID: 19828076] - William M Pardridge, Ruben J Boado. Pharmacokinetics and safety in rhesus monkeys of a monoclonal antibody-GDNF fusion protein for targeted blood-brain barrier delivery.
Pharmaceutical research.
2009 Oct; 26(10):2227-36. doi:
10.1007/s11095-009-9939-6. [PMID: 19609743] - Neeloo Singh, Jaspreet Kaur, Pranav Kumar, Swati Gupta, Nasib Singh, Angana Ghosal, Avijit Dutta, Ashutosh Kumar, Ramapati Tripathi, Mohammad Imran Siddiqi, Chitra Mandal, Anuradha Dube. An orally effective dihydropyrimidone (DHPM) analogue induces apoptosis-like cell death in clinical isolates of Leishmania donovani overexpressing pteridine reductase 1.
Parasitology research.
2009 Oct; 105(5):1317-25. doi:
10.1007/s00436-009-1557-z. [PMID: 19621245] - Alan G Mathew, Sumalee Liamthong, Jun Lin, Yingying Hong. Evidence of class 1 integron transfer between Escherichia coli and Salmonella spp. on livestock farms.
Foodborne pathogens and disease.
2009 Oct; 6(8):959-64. doi:
10.1089/fpd.2009.0263. [PMID: 19630513] - Aner Gurvitz. The essential mycobacterial genes, fabG1 and fabG4, encode 3-oxoacyl-thioester reductases that are functional in yeast mitochondrial fatty acid synthase type 2.
Molecular genetics and genomics : MGG.
2009 Oct; 282(4):407-16. doi:
10.1007/s00438-009-0474-2. [PMID: 19685079] - K Augustin, J Frank, S Augustin, P Langguth, V Ohrvik, C M Witthoft, G Rimbach, S Wolffram. Greeen tea extracts lower serum folates in rats at very high dietary concentrations only and do not affect plasma folates in a human pilot study.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.
2009 Sep; 60(3):103-8. doi:
NULL. [PMID: 19826188] - Mary R Sweeney, Anthony Staines, Leslie Daly, Aisling Traynor, Sean Daly, Steven W Bailey, Patricia B Alverson, June E Ayling, John M Scott. Persistent circulating unmetabolised folic acid in a setting of liberal voluntary folic acid fortification. Implications for further mandatory fortification?.
BMC public health.
2009 Aug; 9(?):295. doi:
10.1186/1471-2458-9-295. [PMID: 19689788] - Ashraf M Ahmed, Emad E A Younis, Yojiro Ishida, Tadashi Shimamoto. Genetic basis of multidrug resistance in Salmonella enterica serovars Enteritidis and Typhimurium isolated from diarrheic calves in Egypt.
Acta tropica.
2009 Aug; 111(2):144-9. doi:
10.1016/j.actatropica.2009.04.004. [PMID: 19375408] - Jae-Sook Park, Sarah K Steinbach, Michel Desautels, Sean M Hemmingsen. Essential role for Schizosaccharomyces pombe pik1 in septation.
PloS one.
2009 Jul; 4(7):e6179. doi:
10.1371/journal.pone.0006179. [PMID: 19587793] - Mizuki Mizukawa, Koji Ohmori, Ayumi Obayashi, Yasuhiro Ishihara, Junji Yoshida, Takahisa Noma, Kazushi Yukiiri, Hiroaki Kosaka, Masakazu Kohno. Effects of combined olmesartan and pravastatin on glucose intolerance and cardiovascular remodeling in a metabolic-syndrome model.
Hypertension research : official journal of the Japanese Society of Hypertension.
2009 Jul; 32(7):617-24. doi:
10.1038/hr.2009.63. [PMID: 19461650] - Sindhu Issac, K Girish Kumar. Voltammetric determination of sulfamethoxazole at a multiwalled carbon nanotube modified glassy carbon sensor and its application studies.
Drug testing and analysis.
2009 Jul; 1(7):350-4. doi:
10.1002/dta.69. [PMID: 20355213] - Antonina Joanna Mazur, Dorota Nowak, Hans Georg Mannherz, Maria Malicka-Błaszkiewicz. Methotrexate induces apoptosis in CaSki and NRK cells and influences the organization of their actin cytoskeleton.
European journal of pharmacology.
2009 Jun; 613(1-3):24-33. doi:
10.1016/j.ejphar.2009.04.020. [PMID: 19383496]