Cymoxanil (BioDeep_00000001188)

   

natural product


代谢物信息卡片


Pesticide4_Cymoxanil_C7H10N4O3_(2E)-2-Cyano-N-(ethylcarbamoyl)-2-(methoxyimino)acetamide

化学式: C7H10N4O3 (198.0753)
中文名称: 霜脲氰
谱图信息: 最多检出来源 Homo sapiens(plant) 28.21%

分子结构信息

SMILES: CCN=C(O)NC(=O)C(C#N)=NOC
InChI: InChI=1S/C7H10N4O3/c1-3-9-7(13)10-6(12)5(4-8)11-14-2/h3H2,1-2H3,(H2,9,10,12,13)/b11-5+

描述信息

CONFIDENCE standard compound; EAWAG_UCHEM_ID 112

同义名列表

3 个代谢物同义名

Cymoxanil; Pesticide4_Cymoxanil_C7H10N4O3_(2E)-2-Cyano-N-(ethylcarbamoyl)-2-(methoxyimino)acetamide; Cymoxanil



数据库引用编号

34 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 6 AXIN2, CACNA1A, CAT, CTH, MYD88, TLR4
Peripheral membrane protein 2 ACHE, GORASP1
Endosome membrane 2 MYD88, TLR4
Endoplasmic reticulum membrane 1 ATP2A1
Nucleus 4 ACHE, AXIN2, CACNA1A, MYD88
cytosol 4 AXIN2, CAT, CTH, MYD88
centrosome 1 AXIN2
nucleoplasm 1 ATP2B1
Cell membrane 5 ACHE, ATP2B1, CACNA1A, TLR4, TNF
Cytoplasmic side 1 GORASP1
Multi-pass membrane protein 4 ATP2A1, ATP2B1, CACNA1A, CACNA1I
Golgi apparatus membrane 1 GORASP1
Synapse 3 ACHE, ATP2B1, CACNA1A
cell surface 5 ACHE, MYD88, TLR4, TNF, TNR
glutamatergic synapse 2 ATP2B1, TNR
Golgi apparatus 3 ACHE, ATRN, GORASP1
Golgi membrane 1 GORASP1
neuromuscular junction 1 ACHE
neuronal cell body 2 CACNA1A, TNF
presynaptic membrane 1 ATP2B1
plasma membrane 10 ACHE, ATP2B1, ATRN, AXIN2, CACNA1A, CACNA1I, CTH, MYD88, TLR4, TNF
synaptic vesicle membrane 1 ATP2B1
Membrane 8 ACHE, ATP2A1, ATP2B1, CACNA1A, CACNA1I, CAT, CTH, TLR4
basolateral plasma membrane 1 ATP2B1
extracellular exosome 4 ATP2B1, ATRN, CAT, CTH
extracellular space 5 ACHE, ATRN, IL6, TNF, TNR
perinuclear region of cytoplasm 3 ACHE, ATP2A1, TLR4
Schaffer collateral - CA1 synapse 1 TNR
mitochondrion 2 ATP2A1, CAT
protein-containing complex 2 CAT, MYD88
intracellular membrane-bounded organelle 2 ATP2B1, CAT
Single-pass type I membrane protein 3 ATRN, CTH, TLR4
Secreted 2 ACHE, IL6
extracellular region 5 ACHE, CAT, IL6, TNF, TNR
[Isoform 2]: Secreted 1 ATRN
mitochondrial matrix 1 CAT
Extracellular side 1 ACHE
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
external side of plasma membrane 2 TLR4, TNF
Secreted, extracellular space, extracellular matrix 1 TNR
beta-catenin destruction complex 1 AXIN2
Early endosome 1 TLR4
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
Membrane raft 2 TNF, TNR
focal adhesion 1 CAT
cis-Golgi network 1 GORASP1
Peroxisome 1 CAT
basement membrane 1 ACHE
sarcoplasmic reticulum 1 ATP2A1
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
collagen-containing extracellular matrix 1 TNR
lateral plasma membrane 1 ATP2B1
Cell projection, ruffle 1 TLR4
ruffle 1 TLR4
receptor complex 1 TLR4
cell projection 2 ATP2B1, CACNA1A
phagocytic cup 2 TLR4, TNF
Basolateral cell membrane 1 ATP2B1
Lipid-anchor, GPI-anchor 1 ACHE
[Isoform 3]: Secreted 1 ATRN
Endomembrane system 1 ATP2A1
I band 1 ATP2A1
monoatomic ion channel complex 1 CACNA1A
Presynaptic cell membrane 1 ATP2B1
side of membrane 1 ACHE
lipopolysaccharide receptor complex 1 TLR4
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 1 CAT
endoplasmic reticulum lumen 1 IL6
voltage-gated calcium channel complex 2 CACNA1A, CACNA1I
Sarcoplasmic reticulum membrane 1 ATP2A1
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 GORASP1
immunological synapse 1 ATP2B1
perineuronal net 1 TNR
Golgi apparatus, cis-Golgi network membrane 1 GORASP1
calcium channel complex 1 ATP2A1
endoplasmic reticulum-Golgi intermediate compartment 1 ATP2A1
H zone 1 ATP2A1
platelet dense tubular network membrane 1 ATP2A1
extrinsic component of cytoplasmic side of plasma membrane 1 MYD88
synaptic cleft 1 ACHE
[Isoform 1]: Cell membrane 1 ATRN
extrinsic component of plasma membrane 1 MYD88
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
catalase complex 1 CAT
interleukin-6 receptor complex 1 IL6
photoreceptor ribbon synapse 1 ATP2B1
tenascin complex 1 TNR
[Isoform H]: Cell membrane 1 ACHE
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Wafaa H Mohamed, Yasmin O El-Amir, Doha Yahia. Ameliorative effect of resveratrol against cymoxanil-mancozeb induced toxicity in rats. Journal of biochemical and molecular toxicology. 2023 Apr; ?(?):e23347. doi: 10.1002/jbt.23347. [PMID: 37009748]
  • Isaack Kikway, Anthony P Keinath, Peter S Ojiambo. Within-season Shift in Fungicide Sensitivity Profiles of Pseudoperonospora cubensis Populations in Response to Chemical Control. Plant disease. 2022 Oct; ?(?):. doi: 10.1094/pdis-09-22-2056-re. [PMID: 36205688]
  • Anita Giglio, Francesco Cavaliere, Piero Giulio Giulianini, Antonio Mazzei, Federica Talarico, Maria Luigia Vommaro, Pietro Brandmayr. Impact of agrochemicals on non-target species: Calathus fuscipes Goeze 1777 (Coleoptera: Carabidae) as model. Ecotoxicology and environmental safety. 2017 Aug; 142(?):522-529. doi: 10.1016/j.ecoenv.2017.04.056. [PMID: 28478378]
  • Xinyue Mei, Min Yang, Bingbing Jiang, Xupo Ding, Weiping Deng, Yumei Dong, Lei Chen, Xili Liu, Shusheng Zhu. Proteomic analysis on zoxamide-induced sensitivity changes in Phytophthora cactorum. Pesticide biochemistry and physiology. 2015 Sep; 123(?):9-18. doi: 10.1016/j.pestbp.2015.01.012. [PMID: 26267047]
  • George Balayiannis, Helen Karasali, Arpad Ambrus. Rapid determination of famoxadone and cymoxanil in commercial pesticide formulation by high performance liquid chromatography using a C18 monolithic rod column. Bulletin of environmental contamination and toxicology. 2014 Dec; 93(6):775-80. doi: 10.1007/s00128-014-1382-7. [PMID: 25236328]
  • Emil Rekanović, Ivana Potočnik, Svetlana Milijašević-Marčić, Miloš Stepanović, Biljana Todorović, Milica Mihajlović. Toxicity of metalaxyl, azoxystrobin, dimethomorph, cymoxanil, zoxamide and mancozeb to Phytophthora infestans isolates from Serbia. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. 2012; 47(5):403-9. doi: 10.1080/03601234.2012.657043. [PMID: 22424065]
  • Pedro Albuquerque, Cristina M R Caridade, Arlete S Rodrigues, Andre R S Marcal, Joana Cruz, Leonor Cruz, Catarina L Santos, Marta V Mendes, Fernando Tavares. Evolutionary and experimental assessment of novel markers for detection of Xanthomonas euvesicatoria in plant samples. PloS one. 2012; 7(5):e37836. doi: 10.1371/journal.pone.0037836. [PMID: 22655073]
  • Edra Jiménez, Fernando Dorta, Cristian Medina, Alberto Ramírez, Ingrid Ramírez, Hugo Peña-Cortés. Anti-phytopathogenic activities of macro-algae extracts. Marine drugs. 2011; 9(5):739-756. doi: 10.3390/md9050739. [PMID: 21673886]
  • Xiao Hong Lu, Shu Sheng Zhu, Yang Bi, Xi Li Liu, Jianjun J Hao. Baseline sensitivity and resistance-risk assessment of Phytophthora capsici to iprovalicarb. Phytopathology. 2010 Nov; 100(11):1162-8. doi: 10.1094/phyto-12-09-0351. [PMID: 20932164]
  • Manuel D Ospina-Giraldo, John G Griffith, Emma W Laird, Christina Mingora. The CAZyome of Phytophthora spp.: a comprehensive analysis of the gene complement coding for carbohydrate-active enzymes in species of the genus Phytophthora. BMC genomics. 2010 Sep; 11(?):525. doi: 10.1186/1471-2164-11-525. [PMID: 20920201]
  • C Skrzypczak. Occurrence of downy mildews on ornamental plants and their control by chemical compounds. Communications in agricultural and applied biological sciences. 2007; 72(4):801-4. doi: . [PMID: 18396813]
  • I Oller, W Gernjak, M I Maldonado, L A Pérez-Estrada, J A Sánchez-Pérez, S Malato. Solar photocatalytic degradation of some hazardous water-soluble pesticides at pilot-plant scale. Journal of hazardous materials. 2006 Dec; 138(3):507-17. doi: 10.1016/j.jhazmat.2006.05.075. [PMID: 16839679]
  • C Skrzypczak. Downy mildews on ornamental plants and their control. Communications in agricultural and applied biological sciences. 2006; 71(3 Pt B):1013-6. doi: . [PMID: 17390852]
  • Howard S Judelson, Geetha Senthil. Investigating the role of ABC transporters in multifungicide insensitivity in Phytophthora infestans. Molecular plant pathology. 2006 Jan; 7(1):17-29. doi: 10.1111/j.1364-3703.2004.00256.x-i1. [PMID: 20507425]
  • E Conte, E Rossi, G Spera, V Pompi, F Carfi', A R Spadoni, M Rosati, M R Montereali, L Donnarumma, W Perconti. Presence of plant protection products in three agricultural areas of Regione Lazio. Communications in agricultural and applied biological sciences. 2003; 68(4 Pt B):865-74. doi: . [PMID: 15151325]
  • Wen-Qiao Wang, Xiu-Ying Han, Xiao-Feng Zhang, Li-Juan Kang, Shu-Long Chen. Synergism in mixtures of cymoxanil and mancozeb on Phytophthora infestans in vivo. Mededelingen (Rijksuniversiteit te Gent. Fakulteit van de Landbouwkundige en Toegepaste Biologische Wetenschappen). 2002; 67(2):299-305. doi: . [PMID: 12701436]
  • Wen-Qiao Wang, Zhi-Qiang Ma, Xiu-Ying Han, Xiao-Feng Zhang, Shu-Long Chen. Detection of resistance to fungicides, mating types and fitness of Phytophthora infestans in Hebei, China. Mededelingen (Rijksuniversiteit te Gent. Fakulteit van de Landbouwkundige en Toegepaste Biologische Wetenschappen). 2002; 67(2):307-14. doi: . [PMID: 12701437]
  • J C Cherton, C Loutelier, C Lange, P Cassier. Direct injection into the HPLC column for monitoring the behaviour of xenobiotics in biological media. II. Behaviour of cymoxanil in fungus and locust and of E-destruxin in locust. The Science of the total environment. 1993 Apr; 132(2-3):381-97. doi: 10.1016/0048-9697(93)90146-w. [PMID: 8475374]