Strophanthin (BioDeep_00000011424)
Secondary id: BioDeep_00001028459
代谢物信息卡片
K-Strophanthin-beta
化学式: C36H54O14 (710.3513)
中文名称: 毒毛花苷K
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1C(C(CC(O1)OC2CCC3(C4CCC5(C(CCC5(C4CCC3(C2)O)O)C6=CC(=O)OC6)C)C=O)OC)OC7C(C(C(C(O7)CO)O)O)O
InChI: InChI=1S/C36H54O14/c1-18-31(50-32-30(42)29(41)28(40)25(15-37)49-32)24(45-3)13-27(47-18)48-20-4-9-34(17-38)22-5-8-33(2)21(19-12-26(39)46-16-19)7-11-36(33,44)23(22)6-10-35(34,43)14-20/h12,17-18,20-25,27-32,37,40-44H,4-11,13-16H2,1-3H3
描述信息
D020011 - Protective Agents > D002316 - Cardiotonic Agents > D002301 - Cardiac Glycosides
D020011 - Protective Agents > D002316 - Cardiotonic Agents > D013328 - Strophanthins
D002317 - Cardiovascular Agents
D004791 - Enzyme Inhibitors
同义名列表
4 个代谢物同义名
Strophanthin; K-Strophanthin-beta; Strophanthin K; k-Strophanthin-beta
数据库引用编号
10 个数据库交叉引用编号
- ChEBI: CHEBI:80753
- KEGG: C16820
- PubChem: 220861
- Metlin: METLIN71367
- CAS: 11005-63-3
- CAS: 560-53-2
- PMhub: MS000025415
- PubChem: 96023344
- NIKKAJI: J14.228J
- KNApSAcK: 80753
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
- 194257 - Castilla elastica: 10.1002/HLCA.19610440403
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Yue Xing, Jing Ying Wang, Ming Yue Li, Zhi Hong Zhang, Hong Lan Jin, Hong Xiang Zuo, Juan Ma, Xuejun Jin. Convallatoxin inhibits IL-1β production by suppressing zinc finger protein 91 (ZFP91)-mediated pro-IL-1β ubiquitination and caspase-8 inflammasome activity.
British journal of pharmacology.
2022 05; 179(9):1887-1907. doi:
10.1111/bph.15758. [PMID: 34825365] - Yi Zhang, Xiujin Shi, Jialun Han, Wenxing Peng, Zhenwei Fang, Yang Zhou, Xiaoyu Xu, Jie Lin, Fucheng Xiao, Limin Zhao, Yang Lin. Convallatoxin Promotes M2 Macrophage Polarization to Attenuate Atherosclerosis Through PPARγ-Integrin αvβ5 Signaling Pathway.
Drug design, development and therapy.
2021; 15(?):803-812. doi:
10.2147/dddt.s288728. [PMID: 33654384] - Bo-Wen Jiang, Wen-Jing Zhang, Ying Wang, Li-Ping Tan, Yong-Li Bao, Zhen-Bo Song, Chun-Lei Yu, Shu-Yue Wang, Lei Liu, Yu-Xin Li. Convallatoxin induces HaCaT cell necroptosis and ameliorates skin lesions in psoriasis-like mouse models.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2020 Jan; 121(?):109615. doi:
10.1016/j.biopha.2019.109615. [PMID: 31707343] - Amitava Dasgupta, Laverne Bourgeois. Convallatoxin, the active cardiac glycoside of lily of the valley, minimally affects the ADVIA Centaur digoxin assay.
Journal of clinical laboratory analysis.
2018 Oct; 32(8):e22583. doi:
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Molecular and cellular biochemistry.
2017 Apr; 428(1-2):23-39. doi:
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European journal of pharmacology.
2014 Dec; 744(?):18-27. doi:
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1972 Oct; 97(40):1485-90. doi:
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Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova.
1972 Aug; 58(8):1281-6. doi:
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Bollettino della Societa italiana di biologia sperimentale.
1972 Feb; 48(3):59-63. doi:
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1972 Feb; 48(3):52-6. doi:
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1972; 12(1):19-22. doi:
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1971 Apr; 177(1):284-90. doi:
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Kardiologiia.
1971 Feb; 11(2):76-84. doi:
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Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimentelle Chirurgie.
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