Dihydrophaseic acid (BioDeep_00000010984)
human metabolite PANOMIX_OTCML-2023 Endogenous natural product
代谢物信息卡片
化学式: C15H22O5 (282.1467)
中文名称: 二氢菜豆酸
谱图信息:
最多检出来源 Viridiplantae(plant) 47.34%
分子结构信息
SMILES: C/C(=C/C(=O)O)/C=C/[C@@]1([C@]2(C)C[C@@H](C[C@@]1(C)OC2)O)O
InChI: InChI=1S/C15H22O5/c1-10(6-12(17)18)4-5-15(19)13(2)7-11(16)8-14(15,3)20-9-13/h4-6,11,16,19H,7-9H2,1-3H3,(H,17,18)/b5-4+,10-6-
描述信息
Dihydrophaseic acid is an apo carotenoid sesquiterpenoid that is phaseic acid in which the keto group has been reduced to the corresponding alcohol such that the two hydroxy groups are on opposite sides of the 6-membered ring. It has a role as a metabolite. It is a 6-hydroxy monocarboxylic acid, a cyclic ether, a tertiary alcohol, a secondary alcohol, an apo carotenoid sesquiterpenoid and an alpha,beta-unsaturated monocarboxylic acid. It is functionally related to a phaseic acid.
Dihydrophaseic acid is a natural product found in Breynia rostrata, Sophora alopecuroides, and other organisms with data available.
Dihydrophaseic acid (DPA), also known as 4-dihydrophaseic acid, belongs to the class of organic compounds known as abscisic acid and derivatives. These are terpene compounds containing the abscisic acid moiety, which is characterized by a 3-methylpenta-2,4-dienoic acid attached to the C1 carbon of a 4-oxocyclohex-2-ene moiety. Dihydrophaseic acid is found in coconut. Dihydrophaseic acid is isolated from French beans.
An apo carotenoid sesquiterpenoid that is phaseic acid in which the keto group has been reduced to the corresponding alcohol such that the two hydroxy groups are on opposite sides of the 6-membered ring.
Isolated from French beans. Dihydrophaseic acid is found in many foods, some of which are sunflower, corn, pulses, and coconut.
同义名列表
15 个代谢物同义名
(2Z,4E)-3-Methyl-5-[(1S)-1alpha-hydroxy-2,6-dimethyl-2alpha,6alpha-(epoxymethano)-4beta-hydroxycyclohexane-1-yl]-2,4-pentadienoic acid; (2Z,4E)-5-[(1R,3S,5R,8S)-3,8-dihydroxy-1,5-dimethyl-6-oxabicyclo[3.2.1]octan-8-yl]-3-methylpenta-2,4-dienoic acid; (2Z,4E)-5-[(1R,3S,5R,8S)-3,8-dihydroxy-1,5-dimethyl-6-oxabicyclo[3.2.1]oct-8-yl]-3-methylpenta-2,4-dienoic acid; 5-(3,8-Dihydroxy-1,5-dimethyl-6-oxabicyclo[3.2.1]oct-8-yl)-3-methyl-2,4-pentadienoic acid, 9CI; cis,trans-4-Dihydrophaseic acid; isomer of dihydrophaseic acid; (-)-Dihydrophaseic acid; 4’-dihydrophaseic acid; 4-Dihydrophaseic acid; Dihydrophaseic acid; (-)-Dihydrophaseate; Dihydrophaseicacid; Dihydrophaseate; DPA; Epidihydrophaseic acid
数据库引用编号
22 个数据库交叉引用编号
- ChEBI: CHEBI:23757
- KEGG: C15971
- PubChem: 11988272
- PubChem: 72833730
- HMDB: HMDB0038660
- Metlin: METLIN53368
- ChEMBL: CHEMBL3594246
- LipidMAPS: LMPR0103050005
- MetaCyc: CPD-7726
- KNApSAcK: C00053080
- KNApSAcK: C00033819
- foodb: FDB018059
- chemspider: 10160739
- CAS: 41756-77-8
- CAS: 60102-38-7
- medchemexpress: HY-116831
- PMhub: MS000024911
- MetaboLights: MTBLC23757
- PubChem: 47205284
- NIKKAJI: J330.632A
- RefMet: Dihydrophaseic acid
- LOTUS: LTS0019935
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
9 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(3)
- Metabolism and regulation:
ATP + CoA + propionate ⟶ AMP + PPi + PROP-CoA
- Secondary metabolism:
GPP + H2O ⟶ PPi + geraniol
- Abscisate degradation I:
ABA + H+ + Oxygen + TPNH ⟶ 8'-hydroxyabscisate + H2O + TPN
INOH(0)
PlantCyc(6)
- abscisic acid degradation to phaseic acid:
A + dihydroxyphaseic acid ⟶ A(H2) + phaseic acid
- abscisic acid degradation to phaseic acid:
2-cis-abscisate + O2 + a reduced [NADPH-hemoprotein reductase] ⟶ 8'-hydroxyabscisate + H2O + an oxidized [NADPH-hemoprotein reductase]
- abscisic acid degradation to phaseic acid:
2-cis-abscisate + O2 + a reduced [NADPH-hemoprotein reductase] ⟶ 8'-hydroxyabscisate + H2O + an oxidized [NADPH-hemoprotein reductase]
- abscisic acid degradation to phaseic acid:
A + dihydroxyphaseic acid ⟶ A(H2) + phaseic acid
- abscisic acid degradation to phaseic acid:
2-cis-abscisate + O2 + a reduced [NADPH-hemoprotein reductase] ⟶ 8'-hydroxyabscisate + H2O + an oxidized [NADPH-hemoprotein reductase]
- abscisic acid degradation to phaseic acid:
A + dihydroxyphaseic acid ⟶ A(H2) + phaseic acid
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
43 个相关的物种来源信息
- 4210 - Asteraceae: LTS0019935
- 99295 - Breynia: LTS0019935
- 1219483 - Breynia rostrata: 10.1016/J.PHYTOCHEM.2009.10.002
- 1219483 - Breynia rostrata: LTS0019935
- 693768 - Cibotiaceae: LTS0019935
- 29587 - Cibotium: LTS0019935
- 32105 - Cibotium glaucum: 10.1104/PP.86.3.857
- 32105 - Cibotium glaucum: LTS0019935
- 3660 - Cucurbita: LTS0019935
- 3661 - Cucurbita maxima: 10.1016/S0031-9422(00)80379-9
- 3661 - Cucurbita maxima: LTS0019935
- 3650 - Cucurbitaceae: LTS0019935
- 3270 - Dicksonia: LTS0019935
- 3271 - Dicksonia antarctica: 10.1104/PP.86.3.857
- 3271 - Dicksonia antarctica: LTS0019935
- 3269 - Dicksoniaceae: LTS0019935
- 2759 - Eukaryota: LTS0019935
- 3803 - Fabaceae: LTS0019935
- 4231 - Helianthus: LTS0019935
- 4232 - Helianthus annuus: 10.1016/0031-9422(88)87046-8
- 4232 - Helianthus annuus: LTS0019935
- 9606 - Homo sapiens: -
- 3433 - Lauraceae: LTS0019935
- 3398 - Magnoliopsida: LTS0019935
- 3434 - Persea: LTS0019935
- 3435 - Persea americana: 10.1271/BBB1961.47.365
- 3435 - Persea americana: LTS0019935
- 3883 - Phaseolus: LTS0019935
- 3885 - Phaseolus vulgaris: 10.1246/BCSJ.60.981
- 3885 - Phaseolus vulgaris: LTS0019935
- 233880 - Phyllanthaceae: LTS0019935
- 241806 - Polypodiopsida: LTS0019935
- 3896 - Sophora: LTS0019935
- 200492 - Sophora alopecuroides: 10.1007/S10600-009-9360-8
- 200492 - Sophora alopecuroides: LTS0019935
- 35493 - Streptophyta: LTS0019935
- 58023 - Tracheophyta: LTS0019935
- 33090 - Viridiplantae: LTS0019935
- 36590 - Xanthium: LTS0019935
- 576365 - Xanthium sibiricum: 10.1021/NP500951S
- 576365 - Xanthium sibiricum: LTS0019935
- 318068 - Xanthium strumarium: 10.1021/NP500951S
- 318068 - Xanthium strumarium: LTS0019935
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Yu-Sheng Shi, Yun-Bao Liu, Shuang-Gang Ma, Yong Li, Jing Qu, Li Li, Shao-Peng Yuan, Qi Hou, Yu-Huan Li, Jian-Dong Jiang, Shi-Shan Yu. Bioactive Sesquiterpenes and Lignans from the Fruits of Xanthium sibiricum.
Journal of natural products.
2015 Jul; 78(7):1526-35. doi:
10.1021/np500951s
. [PMID: 26110443]