gamma-Cadinene (BioDeep_00000001066)

 

Secondary id: BioDeep_00000019475

human metabolite PANOMIX_OTCML-2023 Endogenous natural product


代谢物信息卡片


Naphthalene, 1,2,3,4,4a,5,6,8a-octahydro-7-methyl-4-methylene-1-(1-methylethyl)-, (1alpha,4abeta,8aalpha)-

化学式: C15H24 (204.1878)
中文名称: （-）-γ-卡地宁
谱图信息: 最多检出来源 Chinese Herbal Medicine(not specific) 4.35%

分子结构信息

SMILES: C=C1CC[C@H](C(C)C)[C@H]2C=C(C)CC[C@H]12
InChI: InChI=1S/C42H76NO8P/c1-6-8-10-12-14-16-17-18-19-20-21-22-23-24-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-15-13-11-9-7-2/h14,16,18-19,21-22,24-25,40H,6-13,15,17,20,23,26-39H2,1-5H3/b16-14-,19-18-,22-21-,25-24-/t40-/m1/s1

描述信息

(-)-gamma-cadinene is a member of the cadinene family of sesquiterpenes in which the isopropyl group is cis to the hydrogen at the adjacent bridgehead carbon (the 1R,4aS,8aS enantiomer). It has a role as a metabolite. It is a cadinene, a member of octahydronaphthalenes and a gamma-cadinene. It is an enantiomer of a (+)-gamma-cadinene.
(-)-gamma-Cadinene is a natural product found in Xylopia sericea, Chromolaena odorata, and other organisms with data available.
A member of the cadinene family of sesquiterpenes in which the isopropyl group is cis to the hydrogen at the adjacent bridgehead carbon (the 1R,4aS,8aS enantiomer).
gamma-Cadinene is found in allspice. gamma-Cadinene is a constituent of citronella oil.

同义名列表

35 个代谢物同义名

Naphthalene, 1,2,3,4,4a,5,6,8a-octahydro-7-methyl-4-methylene-1-(1-methylethyl)-, (1alpha,4abeta,8aalpha)-; 1,2,3,4,4a,5,6,8a-Octahydro-7-methyl-4-methylene-1-(1-methylethyl)-(1S,4aR,8aR)-Naphthalene; (1R,4aS,8aS)-7-methyl-4-methylidene-1-(propan-2-yl)-1,2,3,4,4a,5,6,8a-octahydronaphthalene; [1R,(-)]-1,2,3,4,4aalpha,5,6,8abeta-Octahydro-7-methyl-4-methylene-1-isopropylnaphthalene; (1R,4aS,8aS)-7-methyl-4-methylidene-1-propan-2-yl-2,3,4a,5,6,8a-hexahydro-1H-naphthalene; 1.BETA.,6.ALPHA.,7.BETA.H-CADINA-4,10(15)-DIENE; 1BETA,6ALPHA,7BETAH-CADINA-4,10(15)-DIENE; 1beta,6alpha,7ΒH-cadina-4,10(15)-diene; gamma-cadinene, (+)-gamma(1)-isomer; 1Β,6α,7βh-cadina-4,10(15)-diene; WRHGORWNJGOVQY-RBSFLKMASA-N; gamma-cadinene, (-)-isomer; gamma-cadinene, (+)-isomer; (±)-cadina-4,10(15)-diene; CADINENE, .GAMMA.-, (-)-; trans- .gamma.-Cadinene; .GAMMA.-CADINENE, (-)-; Racemic gamma Cadinene; gamma-Cadinene, (-)-; (-)-gamma-Cadinene; (±)-gamma-cadinene; gamma-Cardinene; UNII-2GHT32E0JU; gamma-cadinene; (-)-g-Cadinene; (+)-g-Cadinene; (-)-Γ-cadinene; (±)-γ-cadinene; D-g-Cadinene; Γ-cardinene; g-Cadinene; γ-Cadinene; 2GHT32E0JU; Cadinene-gamma; (-)-gamma-Cadinene



数据库引用编号

20 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

265 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 5 FPR1, FPR2, PIK3C2A, TYR, UMODL1
Endoplasmic reticulum membrane 1 CYP51A1
Nucleus 2 EMX2, PIK3C2A
cytosol 1 PIK3C2A
trans-Golgi network 1 PIK3C2A
nucleoplasm 1 PIK3C2A
Cell membrane 4 FPR1, FPR2, PIK3C2A, UMODL1
Cell projection, axon 1 EMX2
Multi-pass membrane protein 2 FPR1, FPR2
cell surface 1 UMODL1
Golgi apparatus 1 ATRN
Lysosome 1 TYR
plasma membrane 4 ATRN, FPR1, FPR2, PIK3C2A
Membrane 4 CYP51A1, FPR1, FPR2, PIK3C2A
axon 1 EMX2
extracellular exosome 2 ATRN, PIK3C2A
extracellular space 2 ATRN, UMODL1
perinuclear region of cytoplasm 1 TYR
intracellular membrane-bounded organelle 3 CYP51A1, PIK3C2A, TYR
Microsome membrane 1 CYP51A1
Single-pass type I membrane protein 3 ATRN, TYR, UMODL1
Secreted 1 MATN3
extracellular region 1 MATN3
Single-pass membrane protein 1 CYP51A1
[Isoform 2]: Secreted 1 ATRN
external side of plasma membrane 1 UMODL1
Melanosome membrane 1 TYR
Golgi-associated vesicle 1 TYR
vesicle 1 PIK3C2A
extracellular matrix 1 MATN3
collagen-containing extracellular matrix 1 MATN3
chromatin 1 EMX2
Golgi apparatus, trans-Golgi network 1 PIK3C2A
[Isoform 3]: Secreted 1 ATRN
specific granule membrane 1 FPR2
tertiary granule membrane 1 FPR2
Melanosome 1 TYR
clathrin-coated vesicle 1 PIK3C2A
secretory granule membrane 1 FPR1
endoplasmic reticulum lumen 1 MATN3
phosphatidylinositol 3-kinase complex 1 PIK3C2A
matrilin complex 1 MATN3
Cytoplasmic vesicle, clathrin-coated vesicle 1 PIK3C2A
azurophil granule membrane 1 FPR1
ficolin-1-rich granule membrane 2 FPR1, FPR2
[Isoform 1]: Cell membrane 1 ATRN


文献列表

  • Muhammad Zul Afiq Anuar, Wan Mohd Nuzul Hakimi Wan Salleh, Shamsul Khamis, Mohd Azlan Nafiah, Zahid Mat Said. Essential oil composition of Alseodaphne perakensis (Gamble) Kosterm from Malaysia. Natural product research. 2021 Feb; 35(3):508-511. doi: 10.1080/14786419.2019.1636245. [PMID: 31266357]
  • Ana E T Alcoba, Daiana C de Melo, Priscila M de Andrade, Herbert J Dias, Mariana C Pagotti, Lizandra G Magalhães, Walnir G F Júnior, Antônio E M Crotti, Mayker L D Miranda. Chemical composition and in vitro antileishmanial and cytotoxic activities of the essential oils of Ocotea dispersa (Nees) Mez and Ocotea odorifera (Vell) Rohwer (Lauraceae). Natural product research. 2018 Dec; 32(23):2865-2868. doi: 10.1080/14786419.2017.1385007. [PMID: 29022353]
  • Aline Augusti Boligon, Thiago Guilherme Schwanz, Mariana Piana, Rose Vanessa Bandeira, Janaína Kieling Frohlich, Thiele Faccim de Brum, Marina Zadra, Margareth Linde Athayde. Chemical composition and antioxidant activity of the essential oil of Tabernaemontana catharinensis A. DC. leaves. Natural product research. 2013; 27(1):68-71. doi: 10.1080/14786419.2011.653971. [PMID: 22273350]
  • Marina Quartu, Maria P Serra, Marianna Boi, Giuliano Pillolla, Tiziana Melis, Laura Poddighe, Marina Del Fiacco, Danilo Falconieri, Gianfranca Carta, Elisabetta Murru, Lina Cordeddu, Antonio Piras, Maria Collu, Sebastiano Banni. Effect of acute administration of Pistacia lentiscus L. essential oil on rat cerebral cortex following transient bilateral common carotid artery occlusion. Lipids in health and disease. 2012 Jan; 11(?):8. doi: 10.1186/1476-511x-11-8. [PMID: 22239952]
  • Megil McNeil, Petrea Facey, Roy Porter. Essential oils from the Hyptis genus--a review (1909-2009). Natural product communications. 2011 Nov; 6(11):1775-96. doi: . [PMID: 22224308]
  • My Youssef Arjouni, Fouad Bahri, Abderrahmane Romane, M Ahmed El Alaoui El Fels. Chemical composition and antimicrobial activity of essential oil of Cupressus atlantica. Natural product communications. 2011 Oct; 6(10):1519-22. doi: . [PMID: 22164798]
  • Ali Shafaghat. Antibacterial activity and GC/MS analysis of the essential oils from flower, leaf and stem of Origanum vulgare ssp. viride growing wild in north-west Iran. Natural product communications. 2011 Sep; 6(9):1351-2. doi: . [PMID: 21941913]
  • Ali Shafaghat, Khodamali Oji. Nepetalactone content and antibacterial activity of the essential oils from different parts of Nepeta persica. Natural product communications. 2010 Apr; 5(4):625-8. doi: . [PMID: 20433086]
  • Zahra Aghajani, Masoud Kazemi, Mohammad Dakhili, Abdolhossein Rustaiyan. Composition and antimicrobial activity of the essential oil of Artemisia kulbadica from Iran. Natural product communications. 2009 Sep; 4(9):1261-6. doi: ". [PMID: 19831041]
  • Monia Ennajar, Jalloul Bouajila, Ahmed Lebrihi, Florence Mathieu, Manef Abderraba, Aly Raies, Mehrez Romdhane. Chemical composition and antimicrobial and antioxidant activities of essential oils and various extracts of Juniperus phoenicea L. (Cupressacees). Journal of food science. 2009 Sep; 74(7):M364-71. doi: 10.1111/j.1750-3841.2009.01277.x. [PMID: 19895482]
  • Biljana Nikolić, Mihailo Ristić, Srdjan Bojović, Petar D Marin. Variability of the needle essential oils of Pinus peuce from different populations in Montenegro and Serbia. Chemistry & biodiversity. 2008 Jul; 5(7):1377-88. doi: 10.1002/cbdv.200890126. [PMID: 18649304]
  • Vitaly Portnoy, Yael Benyamini, Einat Bar, Rotem Harel-Beja, Shimon Gepstein, James J Giovannoni, Arthur A Schaffer, Joseph Burger, Yaakov Tadmor, Efraim Lewinsohn, Nurit Katzir. The molecular and biochemical basis for varietal variation in sesquiterpene content in melon (Cucumis melo L.) rinds. Plant molecular biology. 2008 Apr; 66(6):647-61. doi: 10.1007/s11103-008-9296-6. [PMID: 18264780]
  • Felipe T Martins, Antônio C Doriguetto, Thiago C de Souza, Kamila R D de Souza, Marcelo H Dos Santos, Maria E C Moreira, Luiz C A Barbosa. Composition, and anti-inflammatory and antioxidant activities of the volatile oil from the fruit peel of Garcinia brasiliensis. Chemistry & biodiversity. 2008 Feb; 5(2):251-8. doi: 10.1002/cbdv.200890022. [PMID: 18293438]
  • Kamel Msaada, Karim Hosni, Mouna Ben Taarit, Thouraya Chahed, Brahim Marzouk. Variations in the essential oil composition from different parts of Coriandrum sativum L. cultivated in Tunisia. The Italian journal of biochemistry. 2007 Mar; 56(1):47-52. doi: ". [PMID: 17511354]
  • K Bel Hadj Salah, M A Mahjoub, J P Chaumont, L Michel, J Millet-Clerc, I Chraeif, S Ammar, Z Mighri, M Aouni. Chemical composition and in vitro antifungal and antioxidant activity of the essential oil and methanolic extract of Teucrium sauvagei Le Houerou. Natural product research. 2006 Oct; 20(12):1089-97. doi: 10.1080/14786410600704748. [PMID: 17127662]
  • Mustafa Z Ozel, Fahrettin Göğüş, Alastair C Lewis. Determination of Teucrium chamaedrys volatiles by using direct thermal desorption-comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry. Journal of chromatography. A. 2006 May; 1114(1):164-9. doi: 10.1016/j.chroma.2006.02.036. [PMID: 16516906]
  • Miklós Tóth, Eva Csonka, Robert J Bartelt, Allard A Cossé, Bruce W Zilkowski, Shin-Etsu Muto, Kenji Mori. Pheromonal activity of compounds identified from male Phyllotreta cruciferae: field tests of racemic mixtures, pure enantiomers, and combinations with allyl isothiocyanate. Journal of chemical ecology. 2005 Nov; 31(11):2705-20. doi: 10.1007/s10886-005-7621-y. [PMID: 16273436]
  • Fabrice Fekam Boyom, Vincent Ngouana, Paul Henri Amvam Zollo, Chantal Menut, Jean Marie Bessiere, Jiri Gut, Philip J Rosenthal. Composition and anti-plasmodial activities of essential oils from some Cameroonian medicinal plants. Phytochemistry. 2003 Dec; 64(7):1269-75. doi: 10.1016/j.phytochem.2003.08.004. [PMID: 14599525]
  • Sandeep Kaur, V K Varshney, Rameshwar Dayal. GC-MS analysis of essential oil of Shorea robusta bast. Journal of Asian natural products research. 2003 Sep; 5(3):231-4. doi: 10.1080/1028602031000105821. [PMID: 12931858]
  • Seied Mahdi Pourmortazavi, Fatemeh Sefidkon, Seied Ghorban Hosseini. Supercritical carbon dioxide extraction of essential oils from Perovskia atriplicifolia Benth. Journal of agricultural and food chemistry. 2003 Aug; 51(18):5414-9. doi: 10.1021/jf0341619. [PMID: 12926891]
  • Roser Vila, Marisa Mundina, Félix Tomi, Ricardo Furlán, Susana Zacchino, Joseph Casanova, Salvador Cañigueral. Composition and antifungal activity of the essential oil of Solidago chilensis. Planta medica. 2002 Feb; 68(2):164-7. doi: 10.1055/s-2002-20253. [PMID: 11859470]
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