2,2'-Methylenediphenol (BioDeep_00000010128)

 

Secondary id: BioDeep_00001874615

human metabolite blood metabolite


代谢物信息卡片


2-[(2-hydroxyphenyl)methyl]phenol

化学式: C13H12O2 (200.0837)
中文名称: 2,2-二羟基二苯甲烷, 亚甲基二苯酚
谱图信息: 最多检出来源 Homo sapiens(blood) 75%

分子结构信息

SMILES: C1=CC=C(C(=C1)CC2=CC=CC=C2O)O
InChI: InChI=1S/C13H12O2/c14-12-7-3-1-5-10(12)9-11-6-2-4-8-13(11)15/h1-8,14-15H,9H2

描述信息

CONFIDENCE standard compound; INTERNAL_ID 860; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4380; ORIGINAL_PRECURSOR_SCAN_NO 4378
CONFIDENCE standard compound; INTERNAL_ID 860; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4391; ORIGINAL_PRECURSOR_SCAN_NO 4390
CONFIDENCE standard compound; INTERNAL_ID 860; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4432; ORIGINAL_PRECURSOR_SCAN_NO 4427
CONFIDENCE standard compound; INTERNAL_ID 860; DATASET 20200303_ENTACT_RP_MIX500; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4033; ORIGINAL_PRECURSOR_SCAN_NO 4030
CONFIDENCE standard compound; INTERNAL_ID 860; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4411; ORIGINAL_PRECURSOR_SCAN_NO 4406
CONFIDENCE standard compound; INTERNAL_ID 860; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4412; ORIGINAL_PRECURSOR_SCAN_NO 4408

同义名列表

8 个代谢物同义名

2-[(2-hydroxyphenyl)methyl]phenol; (2,2-Dihydroxydiphenyl)methane; Bis(2-hydroxyphenyl)methane; Ortho, ortho-bisphenol F; 2,2-Methylenediphenol; 2,2-Bisphenol F; bisphenol F; 2,2'-Bisphenol F



数据库引用编号

19 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 11 ADIG, CCND1, CCNE1, CDH1, FABP4, FOXO1, HELB, LCP1, LPO, PMP2, PPARG
Peripheral membrane protein 1 LCP1
Endosome membrane 1 LEPR
Nucleus 10 ADIG, CCND1, CCNE1, CDH1, ESR2, FABP4, FOXO1, HELB, PMP2, PPARG
cytosol 10 CCND1, CCNE1, CDH1, FABP4, FOXO1, HELB, LCP1, LEP, PMP2, PPARG
nuclear body 1 HELB
trans-Golgi network 1 CDH1
centrosome 2 CCND1, CCNE1
nucleoplasm 8 CCND1, CCNE1, CDH1, CDH17, ESR2, FOXO1, HELB, PPARG
RNA polymerase II transcription regulator complex 1 PPARG
Cell membrane 3 CDH1, CDH17, LEPR
Cytoplasmic side 1 LCP1
lamellipodium 1 CDH1
ruffle membrane 1 LCP1
Multi-pass membrane protein 1 LEPR
Golgi apparatus membrane 1 LEPR
Synapse 1 CRH
cell junction 3 CDH1, CDH17, LCP1
cell surface 2 ADIPOQ, CDH17
glutamatergic synapse 1 CDH1
Golgi apparatus 2 CDH1, LEPR
Golgi membrane 2 INS, LEPR
postsynapse 1 CDH1
endosome 2 CDH1, LEPR
plasma membrane 4 CDH1, CDH17, GCG, LCP1
Membrane 4 ADIG, CDH1, CDH17, LEPR
basolateral plasma membrane 3 CDH17, LEPR, LPO
extracellular exosome 6 CDH1, FABP4, LCP1, LPO, PMP2, SHBG
endoplasmic reticulum 1 ADIPOQ
extracellular space 7 ADIPOQ, CRH, GCG, INS, LCP1, LEP, LPO
perinuclear region of cytoplasm 3 CDH1, LCP1, PPARG
adherens junction 2 CDH1, CDH17
bicellular tight junction 1 CCND1
mitochondrion 3 ESR2, FOXO1, HELB
intracellular membrane-bounded organelle 2 ESR2, PPARG
filopodium 1 LCP1
Single-pass type I membrane protein 3 CDH1, CDH17, LEPR
Secreted 8 ADIG, ADIPOQ, CRH, GCG, INS, LEP, LPO, SHBG
extracellular region 10 ADIG, ADIPOQ, CDH1, CRH, GCG, INS, LEP, LEPR, LPO, SHBG
cytoplasmic side of plasma membrane 1 CDH1
Single-pass membrane protein 2 ADIG, CDH17
Nucleus membrane 1 CCND1
nuclear membrane 2 CCND1, CDH1
external side of plasma membrane 1 LEPR
varicosity 1 CRH
actin cytoskeleton 2 CDH1, LCP1
neuronal dense core vesicle lumen 1 CRH
perikaryon 1 CRH
Cell projection, ruffle membrane 1 LCP1
Cytoplasm, cytoskeleton 1 LCP1
focal adhesion 1 LCP1
Cell junction, adherens junction 1 CDH1
flotillin complex 1 CDH1
collagen trimer 1 ADIPOQ
collagen-containing extracellular matrix 1 ADIPOQ
lateral plasma membrane 1 CDH1
ruffle 1 LCP1
receptor complex 2 LEPR, PPARG
chromatin 3 ESR2, FOXO1, PPARG
cell projection 1 LCP1
phagocytic cup 1 LCP1
Chromosome 1 HELB
podosome 1 LCP1
Golgi apparatus, trans-Golgi network 1 CDH1
actin filament 1 LCP1
Basolateral cell membrane 1 LEPR
site of double-strand break 1 HELB
endosome lumen 1 INS
Lipid droplet 2 ADIG, FABP4
myelin sheath 1 PMP2
secretory granule lumen 2 GCG, INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 2 GCG, INS
transcription repressor complex 1 CCND1
transport vesicle 1 INS
anaphase-promoting complex 1 CDH1
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
[Isoform 2]: Nucleus 1 CDH1
apical junction complex 1 CDH1
Cell junction, desmosome 1 CDH1
desmosome 1 CDH1
catenin complex 2 CDH1, CDH17
cyclin-dependent protein kinase holoenzyme complex 1 CCND1
glial cell projection 1 LCP1
cyclin E1-CDK2 complex 1 CCNE1
[Glucagon-like peptide 1]: Secreted 1 GCG
actin filament bundle 1 LCP1
cyclin D1-CDK4 complex 1 CCND1
cyclin D1-CDK6 complex 1 CCND1
[Isoform E]: Secreted 1 LEPR


文献列表

  • M Bruze, E Zimerson. Contact allergy to dihydroxydiphenyl methanes (bisphenol F). Dermatosen in Beruf und Umwelt. Occupation and environment. 1985; 33(6):216-20. doi: . [PMID: 2936594]