NCBI Taxonomy: 5148

Sordariaceae (ncbi_taxid: 5148)

found 23 associated metabolites at family taxonomy rank level.

Ancestor: Sordariales

Child Taxonomies: Sordaria, Neurospora, Gelasinospora, Asordaria, Boothiella, Copromyces, Coronatomyces, Pseudoneurospora, environmental samples, unclassified Sordariaceae

Pretyrosine

1-[(2S)-2-amino-2-carboxyethyl]-4-hydroxycyclohexa-2,5-diene-1-carboxylic acid

C10H13NO5 (227.0793688)


   

Neurosporene

(6E,8E,10E,12E,14E,16E,18E,20E,22E,26E)-2,6,10,14,19,23,27,31-Octamethyldotriaconta-2,6,8,10,12,14,16,18,20,22,26,30-dodecaene

C40H58 (538.4538268)


Neurosporene, also known as all-trans-neurosporene or 7,8-dihydro-ψ,ψ-carotene, is a member of the class of compounds known as carotenes. Carotenes are a type of unsaturated hydrocarbons containing eight consecutive isoprene units. They are characterized by the presence of two end-groups (mostly cyclohexene rings, but also cyclopentene rings or acyclic groups) linked by a long branched alkyl chain. Carotenes belonging form a subgroup of the carotenoids family. Thus, neurosporene is considered to be an isoprenoid lipid molecule. Neurosporene can be found in a number of food items such as chicory, poppy, silver linden, and towel gourd, which makes neurosporene a potential biomarker for the consumption of these food products. Neurosporene can be found primarily in blood and breast milk. Neurosporene is a carotenoid pigment. It is an intermediate in the biosynthesis of lycopene and a variety of bacterial carotenoids . Neurosporene is a triterpenoid carotenoid identified in human plasma, (PMID: 1416048), serum (PMID: 1416048), milk (PMID: 9164160), and tissues of the human eye (PMID: 11180970). D020011 - Protective Agents > D000975 - Antioxidants > D002338 - Carotenoids

   

Neurosporaxanthin

Neurosporaxanthin; all-trans-Neurosporaxanthin

C35H46O2 (498.34976159999997)


D020011 - Protective Agents > D000975 - Antioxidants > D002338 - Carotenoids

   

Phytofluene

(6E,10E,12E,14E,16Z,18E,22E,26E)-2,6,10,14,19,23,27,31-octamethyldotriaconta-2,6,10,12,14,16,18,22,26,30-decaene

C40H62 (542.4851252)


Phytofluene is a carotenoid pigment with an orange colour found naturally in tomatoes and other vegetables. It is the second product of carotenoid biosynthesis (Wikipedia).

   

y,y-Carotene, 7,7',8,8',11,12-hexahydro-, cis-(9CI)

2,6,10,14,19,23,27,31-octamethyldotriaconta-2,6,10,12,14,16,18,22,26,30-decaene

C40H62 (542.4851252)


   

N6-Succinyl Adenosine

2-({9-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-9H-purin-6-yl}amino)butanedioic acid

C14H17N5O8 (383.1077082)


N6-Succinyl Adenosine (Succinyl-AMP) is a nucleotide derivative that possesses a unique chemical structure and plays significant roles in various biological processes. Its chemical structure consists of adenosine, a nucleoside composed of the nitrogenous base adenine and ribose sugar, with an additional succinyl group attached to the N6 position of the adenine base. This succinyl group is derived from succinic acid, a four-carbon dicarboxylic acid. The presence of the succinyl group at the N6 position of adenine alters the physicochemical properties of adenosine, influencing its interactions with enzymes and other molecules in the cell. This modification is biologically relevant, as N6-succinyl adenosine is involved in several metabolic pathways and regulatory mechanisms. Biologically, N6-succinyl adenosine is known for its role in the regulation of gene expression. It can serve as a substrate for the formation of N6-threonylcarbamoyladenosine (t6A), a key modification found in the wobble position of certain tRNAs. This modification is critical for the efficiency of translation initiation and the accuracy of decoding the genetic code. Moreover, N6-succinyl adenosine is involved in the transsulfuration pathway, a metabolic route that interconverts sulfur-containing amino acids. It acts as a precursor for the synthesis of cysteine, an essential amino acid that plays a vital role in protein structure and function, as well as in the synthesis of glutathione, a major antioxidant in the cell. Additionally, N6-succinyl adenosine has been implicated in the process of protein succinylation, a novel post-translational modification where the succinyl group is transferred to lysine residues of proteins. This modification can affect protein function, stability, and cellular signaling pathways. 2-({9-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-9H-purin-6-yl}amino)butanedioic acid belongs to the class of organic compounds known as purine nucleosides. Purine nucleosides are compounds comprising a purine base attached to a ribosyl or deoxyribosyl moiety. Based on a literature review very few articles have been published on 2-({9-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-9H-purin-6-yl}amino)butanedioic acid. This compound has been identified in human blood as reported by (PMID: 31557052 ). N6-succinyl adenosine is not a naturally occurring metabolite and is only found in those individuals exposed to this compound or its derivatives. Technically N6-Succinyl Adenosine is part of the human exposome. The exposome can be defined as the collection of all the exposures of an individual in a lifetime and how those exposures relate to health. An individual's exposure begins before birth and includes insults from environmental and occupational sources.

   

zeta-Carotene

7,8,7,8-Tetrahydro-psi-psi-carotene

C40H60 (540.469476)


D020011 - Protective Agents > D000975 - Antioxidants > D002338 - Carotenoids Window width to select the precursor ion was 3 Da.; CONE_VOLTAGE is 10 V.; This record was created by the financial support of MEXT/JSPS KAKENHI Grant Number 19HP8024 to the Mass Spectrometry Society of Japan. Window width to select the precursor ion was 3 Da.; CONE_VOLTAGE is 5 V.; This record was created by the financial support of MEXT/JSPS KAKENHI Grant Number 19HP8024 to the Mass Spectrometry Society of Japan.

   

phytofluene

(12E,16E,18E,22E,26E)-2,6,10,14,19,23,27,31-octamethyldotriaconta-2,6,10,12,14,16,18,22,26,30-decaene

C40H62 (542.4851252)


D020011 - Protective Agents > D000975 - Antioxidants > D002338 - Carotenoids Phytofluene is a carotenoid pigment with an orange color found naturally in tomatoes and other vegetables. It is the second product of carotenoid biosynthesis. It is formed from phytoene in a desaturation reaction leading to the formation of five conjugated double bonds. In the following step, addition of carbon-carbon conjugated double bonds leads to the formation of z-carotene and appearance of visible color.; Phytofluene is a carotenoid pigment with an orange color found naturally in tomatoes and other vegetables. It is the second product of carotenoid biosynthesis. Phytofluene is found in many foods, some of which are bitter gourd, yellow bell pepper, caraway, and pepper (c. annuum).

   

Neurosporene

Neurosporene

C40H58 (538.4538268)


D020011 - Protective Agents > D000975 - Antioxidants > D002338 - Carotenoids

   

Prephenic acid

Prephenic acid

C10H10O6 (226.04773600000001)


An oxo dicarboxylic acid that consists of 4-hydroxycyclohexa-2,5-diene-1-carboxylic acid substituted by a 2-carboxy-2-oxoethyl group at position 1.

   

2,6,10,14,19,23,27,31-octamethyldotriaconta-2,6,10,12,14,16,18,22,26,30-decaene

2,6,10,14,19,23,27,31-octamethyldotriaconta-2,6,10,12,14,16,18,22,26,30-decaene

C40H62 (542.4851252)


   

(5s)-4-benzyl-5-hydroxy-3-phenyl-5h-furan-2-one

(5s)-4-benzyl-5-hydroxy-3-phenyl-5h-furan-2-one

C17H14O3 (266.0942894)


   

(1r,2s,4r,5r,8r,9s,11r)-2-({[(2r,3s,4s,5s,6r)-3,4-dihydroxy-5-methoxy-6-methyloxan-2-yl]oxy}methyl)-9-formyl-13-isopropyl-5-methyltetracyclo[7.4.0.0²,¹¹.0⁴,⁸]tridec-12-ene-1-carboxylic acid

(1r,2s,4r,5r,8r,9s,11r)-2-({[(2r,3s,4s,5s,6r)-3,4-dihydroxy-5-methoxy-6-methyloxan-2-yl]oxy}methyl)-9-formyl-13-isopropyl-5-methyltetracyclo[7.4.0.0²,¹¹.0⁴,⁸]tridec-12-ene-1-carboxylic acid

C27H40O8 (492.272304)


   

(1r,2s,4r,5r,8r,9s,11r)-9-formyl-2-({[(2s,3s,4r,5s,6s)-3-hydroxy-4-{[(2z,5e,7s)-7-hydroxy-2-methyl-4-oxoocta-2,5-dienoyl]oxy}-5-methoxy-6-methyloxan-2-yl]oxy}methyl)-13-isopropyl-5-methyltetracyclo[7.4.0.0²,¹¹.0⁴,⁸]tridec-12-ene-1-carboxylic acid

(1r,2s,4r,5r,8r,9s,11r)-9-formyl-2-({[(2s,3s,4r,5s,6s)-3-hydroxy-4-{[(2z,5e,7s)-7-hydroxy-2-methyl-4-oxoocta-2,5-dienoyl]oxy}-5-methoxy-6-methyloxan-2-yl]oxy}methyl)-13-isopropyl-5-methyltetracyclo[7.4.0.0²,¹¹.0⁴,⁸]tridec-12-ene-1-carboxylic acid

C36H50O11 (658.335295)


   

[5-formyl-4-methoxy-2-oxo-6-(prop-1-en-1-yl)pyran-3-yl]methyl acetate

[5-formyl-4-methoxy-2-oxo-6-(prop-1-en-1-yl)pyran-3-yl]methyl acetate

C13H14O6 (266.0790344)


   

2-(5-aminoimidazol-1-yl)-5-(hydroxymethyl)oxolane-3,4-diol

2-(5-aminoimidazol-1-yl)-5-(hydroxymethyl)oxolane-3,4-diol

C8H13N3O4 (215.0906018)


   

methyl 4,8-dihydroxy-6-methyl-9-oxo-4,9a-dihydro-1h-xanthene-4a-carboxylate

methyl 4,8-dihydroxy-6-methyl-9-oxo-4,9a-dihydro-1h-xanthene-4a-carboxylate

C16H16O6 (304.0946836)


   

(1s,12r,15r)-1-hydroxy-7-methoxy-10-(3-methylbut-2-en-1-yl)-12-(2-methylprop-1-en-1-yl)-10,13,19-triazapentacyclo[11.7.0.0³,¹¹.0⁴,⁹.0¹⁵,¹⁹]icosa-3(11),4,6,8-tetraene-2,14,20-trione

(1s,12r,15r)-1-hydroxy-7-methoxy-10-(3-methylbut-2-en-1-yl)-12-(2-methylprop-1-en-1-yl)-10,13,19-triazapentacyclo[11.7.0.0³,¹¹.0⁴,⁹.0¹⁵,¹⁹]icosa-3(11),4,6,8-tetraene-2,14,20-trione

C27H31N3O5 (477.2263596)


   

(2s)-1-[4-(methoxymethyl)phenoxy]but-3-yn-2-ol

(2s)-1-[4-(methoxymethyl)phenoxy]but-3-yn-2-ol

C12H14O3 (206.0942894)


   

(2s,3r,4e)-5-{2-[({2-[(1e,3r,4s)-3,4-dihydroxypent-1-en-1-yl]-6-hydroxyphenyl}methoxy)methyl]-3-hydroxyphenyl}pent-4-ene-2,3-diol

(2s,3r,4e)-5-{2-[({2-[(1e,3r,4s)-3,4-dihydroxypent-1-en-1-yl]-6-hydroxyphenyl}methoxy)methyl]-3-hydroxyphenyl}pent-4-ene-2,3-diol

C24H30O7 (430.199143)


   

(18e)-2,6,10,14,19,23,27,31-octamethyldotriaconta-2,6,10,14,16,18,22,26,30-nonaene

(18e)-2,6,10,14,19,23,27,31-octamethyldotriaconta-2,6,10,14,16,18,22,26,30-nonaene

C40H64 (544.5007744)


   

(2s,3r,4e)-5-[2-({2-[(1e,3r,4s)-3,4-dihydroxypent-1-en-1-yl]-4-hydroxy-3-(hydroxymethyl)phenyl}methyl)-3-hydroxyphenyl]pent-4-ene-2,3-diol

(2s,3r,4e)-5-[2-({2-[(1e,3r,4s)-3,4-dihydroxypent-1-en-1-yl]-4-hydroxy-3-(hydroxymethyl)phenyl}methyl)-3-hydroxyphenyl]pent-4-ene-2,3-diol

C24H30O7 (430.199143)


   

{4,5-dimethoxy-7-methyl-2-oxo-5h,7h,8h-pyrano[3,2-c]pyran-3-yl}methyl acetate

{4,5-dimethoxy-7-methyl-2-oxo-5h,7h,8h-pyrano[3,2-c]pyran-3-yl}methyl acetate

C14H18O7 (298.10524780000003)