Exact Mass: 324.1182
Exact Mass Matches: 324.1182
Found 500 metabolites which its exact mass value is equals to given mass value 324.1182,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Corylifolinin
Isobavachalcone is a member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at positions 4, 2 and 4 and a prenyl group at position 3. It has a role as an antibacterial agent, a platelet aggregation inhibitor and a metabolite. It is a polyphenol and a member of chalcones. It is functionally related to a trans-chalcone. Isobavachalcone is a natural product found in Broussonetia papyrifera, Anthyllis hermanniae, and other organisms with data available. See also: Angelica keiskei top (part of). A member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at positions 4, 2 and 4 and a prenyl group at position 3. Isobavachalcone (Corylifolinin) is derived from Psoralea corylifolia Linn. and is a potent inhibitor of Akt signaling pathway, which induces apoptosis in human cancer cells (Inhibits OVCAR-8 cell growth with an IC50 value of 7.92 μM). Isobavachalcone also induces Reactive Oxyen Species (ROS) generation in OVCAR-8 cells and has exhibit cancer anti-promotive and anti-proliferative activity[1]. Isobavachalcone (Corylifolinin) is derived from Psoralea corylifolia Linn. and is a potent inhibitor of Akt signaling pathway, which induces apoptosis in human cancer cells (Inhibits OVCAR-8 cell growth with an IC50 value of 7.92 μM). Isobavachalcone also induces Reactive Oxyen Species (ROS) generation in OVCAR-8 cells and has exhibit cancer anti-promotive and anti-proliferative activity[1]. Isobavachalcone (Corylifolinin) is derived from Psoralea corylifolia Linn. and is a potent inhibitor of Akt signaling pathway, which induces apoptosis in human cancer cells (Inhibits OVCAR-8 cell growth with an IC50 value of 7.92 μM). Isobavachalcone also induces Reactive Oxyen Species (ROS) generation in OVCAR-8 cells and has exhibit cancer anti-promotive and anti-proliferative activity[1].
Glabranin
Glabranin is a dihydroxyflavanone that is pinocembrin substituted by a prenyl group at position 8. It has a role as a plant metabolite. It is a dihydroxyflavanone and a (2S)-flavan-4-one. It is functionally related to a pinocembrin. Glabranin is a natural product found in Sophora tomentosa, Annona squamosa, and other organisms with data available. A dihydroxyflavanone that is pinocembrin substituted by a prenyl group at position 8. Saponin from licorice (Glycyrrhiza glabra). Glabranin B is found in tea and herbs and spices. Origin: Plant, Pyrans Glabranin. CAS Common Chemistry. CAS, a division of the American Chemical Society, n.d. https://commonchemistry.cas.org/detail?cas_rn=41983-91-9 (retrieved 2024-07-09) (CAS RN: 41983-91-9). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
Furaltadone
D000890 - Anti-Infective Agents > D023303 - Oxazolidinones C254 - Anti-Infective Agent > C52588 - Antibacterial Agent
Prazepam
Prazepam is only found in individuals that have used or taken this drug. It is a benzodiazepine that is used in the treatment of anxiety disorders. It is a schedule IV drug in the U.S. Prazepam is believed to stimulate GABA receptors in the ascending reticular activating system. Since GABA is inhibitory, receptor stimulation increases inhibition and blocks both cortical and limbic arousal following stimulation of the brain stem reticular formation. D002492 - Central Nervous System Depressants > D014149 - Tranquilizing Agents > D014151 - Anti-Anxiety Agents D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D014149 - Tranquilizing Agents N - Nervous system > N05 - Psycholeptics > N05B - Anxiolytics > N05BA - Benzodiazepine derivatives C78272 - Agent Affecting Nervous System > C29756 - Sedative and Hypnotic > C1012 - Benzodiazepine D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants D018377 - Neurotransmitter Agents > D018682 - GABA Agents > D018757 - GABA Modulators C78272 - Agent Affecting Nervous System > C28197 - Antianxiety Agent
(R)-Glabridin
(R)-Glabridin is found in herbs and spices. (R)-Glabridin is isolated from Glycyrrhiza glabra (licorice). Isolated from Glycyrrhiza glabra (licorice). (R)-Glabridin is found in tea and herbs and spices. C26170 - Protective Agent > C275 - Antioxidant > C306 - Bioflavonoid Glabridin is a natural isoflavan from Glycyrrhiza uralensis, binds to and activates PPARγ, with an EC50 of 6115 nM. Glabridin exhibits antioxidant, anti-bacterial, anti-nephritic, anti-diabetic, anti-fungal, antitumor, anti-inflammatory, antiosteoporotic, cardiovascular protective, neuroprotective and radical scavenging activities[1][2]. Glabridin is a natural isoflavan from Glycyrrhiza uralensis, binds to and activates PPARγ, with an EC50 of 6115 nM. Glabridin exhibits antioxidant, anti-bacterial, anti-nephritic, anti-diabetic, anti-fungal, antitumor, anti-inflammatory, antiosteoporotic, cardiovascular protective, neuroprotective and radical scavenging activities[1][2]. Glabridin is a natural isoflavan from Glycyrrhiza uralensis, binds to and activates PPARγ, with an EC50 of 6115 nM. Glabridin exhibits antioxidant, anti-bacterial, anti-nephritic, anti-diabetic, anti-fungal, antitumor, anti-inflammatory, antiosteoporotic, cardiovascular protective, neuroprotective and radical scavenging activities[1][2].
Phaseollidin
Phaseollidin is found in common bean. Phaseollidin is isolated from kidney bean Phaseolus vulgaris, mung bean Phaseolus aureus, rice bean Phaseolus calcaratus, papadi Dolichos biflorus, and hyacinth bean Lablab niger.
Acetohexamide
Acetohexamide is only found in individuals that have used or taken this drug. It is a sulfonylurea hypoglycemic agent that is metabolized in the liver to 1-hydrohexamide. [PubChem]Sulfonylureas such as acetohexamide bind to an ATP-dependent K+ channel on the cell membrane of pancreatic beta cells. This inhibits a tonic, hyperpolarizing outflux of potassium, which causes the electric potential over the membrane to become more positive. This depolarization opens voltage-gated Ca2+ channels. The rise in intracellular calcium leads to increased fusion of insulin granulae with the cell membrane, and therefore increased secretion of (pro)insulin. A - Alimentary tract and metabolism > A10 - Drugs used in diabetes > A10B - Blood glucose lowering drugs, excl. insulins > A10BB - Sulfonylureas C78276 - Agent Affecting Digestive System or Metabolism > C29711 - Anti-diabetic Agent > C97936 - Sulfonylurea Antidiabetic Agent D007004 - Hypoglycemic Agents
Phaseollinisoflavan
Phytoalexin from Phaseolus vulgaris (kidney bean), other Phaseolus subspecies and Glycyrrhiza glabra (licorice). Phaseollinisoflavan is found in many foods, some of which are green bean, yellow wax bean, herbs and spices, and common bean. Phaseollinisoflavan is found in common bean. Phytoalexin from Phaseolus vulgaris (kidney bean), other Phaseolus species and Glycyrrhiza glabra (licorice
N-(6-Cyano-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl)-N-methylethanesulfonamide
D002317 - Cardiovascular Agents > D026902 - Potassium Channel Blockers D049990 - Membrane Transport Modulators
Mycocyclosin
An organic heterotetracyclic compound obtained via intramolecular oxidative aromatic coupling of cyclo(L-tyrosyl-L-tyrosyl). D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D054659 - Diketopiperazines
Chromanol 293B
D002317 - Cardiovascular Agents > D026902 - Potassium Channel Blockers D049990 - Membrane Transport Modulators
(S)-5,7-Dihydroxy-6-prenylflavanone
(S)-5,7-Dihydroxy-6-prenylflavanone is found in herbs and spices. (S)-5,7-Dihydroxy-6-prenylflavanone is a constituent of Glycyrrhiza glabra (licorice). Constituent of Glycyrrhiza glabra (licorice). (S)-5,7-Dihydroxy-6-prenylflavanone is found in tea and herbs and spices.
(E)-2',4,4'-Trihydroxy-3-prenylchalcone
(E)-2,4,4-Trihydroxy-3-prenylchalcone is found in herbs and spices. (E)-2,4,4-Trihydroxy-3-prenylchalcone is a constituent of hairy root cultures of Glycyrrhiza glabra (licorice)
Moracin I
Isolated from Morus alba (white mulberry) infected with Fusarium solani. Moracin I is found in mulberry and fruits. Moracin I is found in fruits. Moracin I is isolated from Morus alba (white mulberry) infected with Fusarium solani.
6-(3-methylbut-2-en-1-yl)-8,17-dioxatetracyclo[8.7.0.0(2),.0(1)(1),(1)]heptadeca-2(7),3,5,11(16),12,14-hexaene-5,14-diol
DHAP(10:0)
DHAP(10:0) is the decanoyl derivative of Dihydroxyacetone phosphate. It is also known as an alkyl-DHAP. This compound is formed by decanoic acid reacting with DHAP. Alkyl-DHAPs are intermediates in the synthesis of ether phospholipids. The initial steps of ether phospholipid biosynthesis take place in peroxisomes. Alkyl-dihydroxyacetonephosphate synthase is the peroxisomal enzyme that actually introduces the ether linkage. Levels of Alkyl-DHAP have been found to be strongly reduced in human fibroblasts derived from Zellweger syndrome and rhizomelic chondrodysplasia punctata patients. Four other enzymes are known to be involved in the metabolism of acyl-DHAP and alkyl-DHAP. These include: acyl-DHAP/alkyl-DHAP oxidoreductase, DHAP acyltransferase, alkyl-DHAP phosphohydrolase, and a dinitrofluorobenzene-insensitive acyl-DHAP acylhydrolase. Dihydroxyacetone phosphate (DHAP) is a biochemical compound primarily involved in the glycolysis metabolic pathway. DHAP is also the product of the dehydrogenation of L-glycerol-3-phosphate which is part of the entry of glycerol (sourced from triglycerides) into the glycolytic pathway. Conversely, reduction of glycolysis-derived DHAP to L-glycerol-3-phosphate provides adipose cells with the activated glycerol backbone they require to synthesize new triglycerides. Both reactions are catalyzed by the enzyme glycerol 3-phosphate dehydrogenase with NAD+/NADH as cofactor. DHAP may be referred to as glycerone phosphate in older texts. [HMDB] DHAP(10:0) is the decanoyl derivative of Dihydroxyacetone phosphate. It is also known as an alkyl-DHAP. This compound is formed by decanoic acid reacting with DHAP. Alkyl-DHAPs are intermediates in the synthesis of ether phospholipids. The initial steps of ether phospholipid biosynthesis take place in peroxisomes. Alkyl-dihydroxyacetonephosphate synthase is the peroxisomal enzyme that actually introduces the ether linkage. Levels of Alkyl-DHAP have been found to be strongly reduced in human fibroblasts derived from Zellweger syndrome and rhizomelic chondrodysplasia punctata patients. Four other enzymes are known to be involved in the metabolism of acyl-DHAP and alkyl-DHAP. These include: acyl-DHAP/alkyl-DHAP oxidoreductase, DHAP acyltransferase, alkyl-DHAP phosphohydrolase, and a dinitrofluorobenzene-insensitive acyl-DHAP acylhydrolase. Dihydroxyacetone phosphate (DHAP) is a biochemical compound primarily involved in the glycolysis metabolic pathway. DHAP is also the product of the dehydrogenation of L-glycerol-3-phosphate which is part of the entry of glycerol (sourced from triglycerides) into the glycolytic pathway. Conversely, reduction of glycolysis-derived DHAP to L-glycerol-3-phosphate provides adipose cells with the activated glycerol backbone they require to synthesize new triglycerides. Both reactions are catalyzed by the enzyme glycerol 3-phosphate dehydrogenase with NAD+/NADH as cofactor. DHAP may be referred to as glycerone phosphate in older texts.
3-Methylsulfonyl-4-piperidin-1-ylbenzoyl guanidine
(4-Acetamidophenyl) (2S)-2-acetamido-4-methylsulfanylbutanoate
Bavachalcone
Isobavachalcone (Corylifolinin) is derived from Psoralea corylifolia Linn. and is a potent inhibitor of Akt signaling pathway, which induces apoptosis in human cancer cells (Inhibits OVCAR-8 cell growth with an IC50 value of 7.92 μM). Isobavachalcone also induces Reactive Oxyen Species (ROS) generation in OVCAR-8 cells and has exhibit cancer anti-promotive and anti-proliferative activity[1]. Isobavachalcone (Corylifolinin) is derived from Psoralea corylifolia Linn. and is a potent inhibitor of Akt signaling pathway, which induces apoptosis in human cancer cells (Inhibits OVCAR-8 cell growth with an IC50 value of 7.92 μM). Isobavachalcone also induces Reactive Oxyen Species (ROS) generation in OVCAR-8 cells and has exhibit cancer anti-promotive and anti-proliferative activity[1]. Isobavachalcone (Corylifolinin) is derived from Psoralea corylifolia Linn. and is a potent inhibitor of Akt signaling pathway, which induces apoptosis in human cancer cells (Inhibits OVCAR-8 cell growth with an IC50 value of 7.92 μM). Isobavachalcone also induces Reactive Oxyen Species (ROS) generation in OVCAR-8 cells and has exhibit cancer anti-promotive and anti-proliferative activity[1].
7-Hydroxy-2-(4-hydroxyphenyl)-6-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one
Bicisate
3-((4-(5-(Hydroxymethyl)-2-oxo-3-oxazolidinyl)phenoxy)methyl)benzonitrile
Difructose anhydride III
N-(N-Formyl-L-methionyl)-L-phenylalanine
Furaltadone
2,2-Dimethyl-4-(4-methylsulfonylphenyl)-5-propoxyfuran-3-one
NCI60_008951
Bavachin
Bavachin is a natural product found in Broussonetia papyrifera, Cullen corylifolium, and other organisms with data available. Bavachin, a flavonoid first isolated from seeds of P. corylifolia, acts as a phytoestrogen that activates the estrogen receptors ERα and ERβ with EC50s of 320 and 680 nM, respectively. Bavachin, a flavonoid first isolated from seeds of P. corylifolia, acts as a phytoestrogen that activates the estrogen receptors ERα and ERβ with EC50s of 320 and 680 nM, respectively.
Glabridin
Glabridin is a member of the class of hydroxyisoflavans that is (R)-isoflavan substituted by hydroxy groups at positions 2 and 4 and a 2,2-dimethyl-2H-pyran group across positions 7 and 8 respectively. It has a role as an antiplasmodial drug. It derives from a hydride of a (R)-isoflavan. Glabridin is a natural product found in Ornithopus sativus, Glycyrrhiza glabra, and other organisms with data available. See also: Glycyrrhiza Glabra (part of). C26170 - Protective Agent > C275 - Antioxidant > C306 - Bioflavonoid Glabridin is a natural isoflavan from Glycyrrhiza uralensis, binds to and activates PPARγ, with an EC50 of 6115 nM. Glabridin exhibits antioxidant, anti-bacterial, anti-nephritic, anti-diabetic, anti-fungal, antitumor, anti-inflammatory, antiosteoporotic, cardiovascular protective, neuroprotective and radical scavenging activities[1][2]. Glabridin is a natural isoflavan from Glycyrrhiza uralensis, binds to and activates PPARγ, with an EC50 of 6115 nM. Glabridin exhibits antioxidant, anti-bacterial, anti-nephritic, anti-diabetic, anti-fungal, antitumor, anti-inflammatory, antiosteoporotic, cardiovascular protective, neuroprotective and radical scavenging activities[1][2]. Glabridin is a natural isoflavan from Glycyrrhiza uralensis, binds to and activates PPARγ, with an EC50 of 6115 nM. Glabridin exhibits antioxidant, anti-bacterial, anti-nephritic, anti-diabetic, anti-fungal, antitumor, anti-inflammatory, antiosteoporotic, cardiovascular protective, neuroprotective and radical scavenging activities[1][2].
Bavachalcone
Bavachalcone is a member of chalcones. Bavachalcone is a natural product found in Broussonetia papyrifera, Cullen corylifolium, and Sophora prostrata with data available. Bavachalcone is a compound isolated from psoralen. It is widely used in traditional Chinese medicine and has antibiotic and anti-cancer activities. Bavachalcone is a compound isolated from psoralen. It is widely used in traditional Chinese medicine and has antibiotic and anti-cancer activities.
Isobavachin
Isobavachin is a member of flavanones. Isobavachin is a natural product found in Brosimum acutifolium, Erythrina sigmoidea, and other organisms with data available. Isobavachin, an antioxidant isaolated from Psoralea corylifolia with a prenyl group at position 8 of ring A, promotes neuronal differentiation and the potential role of its protein prenylation[1][2]. Isobavachin, an antioxidant isaolated from Psoralea corylifolia with a prenyl group at position 8 of ring A, promotes neuronal differentiation and the potential role of its protein prenylation[1][2].
Calocarpin
2,3,5,8,10-Pentahydroxy-3-methyl-6-methoxy-1,2,3,4,4a,9a-hexahydroanthracene-9(10H)-one
Flemistrictin E
Flemistrictin F
6-Carboxy-5-hydroxy-2,2-dimethyl-7-(2-phenylethyl)chromene
1-(1,3-Benzodioxole-5-yl)-2,3-dimethyl-6,7-(methylenedioxy)-1,2,3,4-tetrahydronaphthalene
Crotaramosmin
1-(2,5-dihydro-6,8-dihydroxy-3-methyl-1-benzoxepin-7-yl)-3-phenyl-1-propanone
4-Hydroxycordoin
A member of the class of chalcones that is trans-chalcone substituted by hydroxy groups at position 4 and 2 and a (3-methylbut-2-en-1-yl)oxy group at position 4. It has been isolated from Lonchocarpus neuroscapha.
10,10-Dimethyl-10a-[2-(2-thienyl)vinyl]-3,4,10,10a-tetrahydropyrimido[1,2-a]indol-2(1H)-one
1-(2,4-dihydroxyphenyl)-3-[4-(3-methylbut-2-enoxy)phenyl]prop-2-en-1-one
dimethyl 2,4-diphenylcyclobutane-1,3-dicarboxylate
1,2-Dihydro,1-hydroxy-(8alpha,9beta)-form-1,7,8,9-Tetrahydro-1,9-dihydroxy-4-methoxy-5-methyl-8-(1-methylethenyl)-3H-furo[3,4-f][1]benzopyran-3-one,
(E)-cinnamyl (E)-3,4-dimethoxycinnamate|(E)-cinnamyl (E)-O,O-dimethyl-caffeate|(E)-cinnamyl-(E)-O,O-dimethyl caffeate|cinnamyl 3,4-dimethoxycinnamate
(2E,8E)-2,8-Decadiene-4,6-diyne-1,10-diol 1-O-??-D-glucopyranoside|(2E,8E)-deca-2,8-diene-4,6-diyne-1,10-diol 1-O-beta-D-glucopyranoside
5-(E)-propenyl-2-(2,4,5-trimethoxyphenyl)benzofuran|6-Demethoxy,5-methoxy-5-(1-Propenyl)-2-(2,4,6-trimethoxyphenyl)benzofuran
O-beta-D-Xylopyranoside-(R)-5,6,7,8-Tetrahydro-6-hydroxy-2-naphthalenecarboxylic acid
1,1,10-Trimethyl-3-hydroxy-7-isopropylanthracene-2,5,6(1H)-trione
1-[2,4-dihydroxy-5-(3-methylbut-2-enyl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one
2-(3,4-methylenedioxyphenyl)-5-(1,2-dihydroxypropyl)-3-methylbenzofuran
2,3-dihydro-3,7-dihydroxy-6-(3-methyl-2-butenyl)-2-phenyl-4h -1-benzopyran-4-one
2-(3,4-Dimethoxyphenyl)-3-methyl-7-(2-propenyl)benzofuran-5-ol
3(R)-deca-4,6,8-triyne-1,3-diol 1-O-beta-D-glucopyranoside|bidensyneoside B
2,2-Dimethyl-5-hydroxy-7-(2-phenylethyl)-2H-1-benzopyran-6-carboxylic acid
2-(4-hydroxy-3-methoxyphenyl)-1,3-propanediol triacetate
5H-benzo[g]-1,3-benzodioxolo[5,6,4]quinoline-6,7,7a,8-tetrahydro-7-nitroso-10-methoxy-(7aR)|N-nitrosoxylopine
Sanggenofuran B
Sanggenofuran B is a natural product found in Morus cathayana with data available.
1-(4-hydroxy-3-methoxyphenyl)-7-phenyl-5-hydroxy-4,6-heptadiene-3-one
(E)-1-(5-hydroxy-2,2-dimethyl-3,4-dihydrochromen-8-yl)-3-(4-hydroxyphenyl)prop-2-en-1-one
3-O-trans-p-methoxycinnamoyl-alpha-L-rhamnopyranose
3alpha-hydroxy-9(10->20)abeo-abieta-1,5,8,10(20),13-pentaene-7,11,12-trione
5-Methoxy-6-methoxy-7-(2,3-dihydroxy-3-methylbutoxy)coumarin
Bleitetraaethyl|Tetraaethyl-plumban|tetraethyl lead|tetraethyllead|tetraethyllead(IV)|tetraethylplumbane|tetraetyllead
3-(4-hydroxy-3-methoxyphenyl)-1,2-propanediol triacetate
1-(4-hydroxy-3-methoxyphenyl)-7-methoxy-2,3-dimethylnaphthalen-6-ol
6,9-dihydroxy-7,8-dimethoxy-2-propyl-2,3,3a,9b-tetrahydro-furo[3,2-c]isochromen-5-one|Hydroxymonocerin
(+-)-alpha-truxillic acid monoethyl ester|(+-)-alpha-Truxillsaeure-monoaethylester
licarinB
Licarin B is a natural product found in Magnolia kachirachirai, Licaria guianensis, and other organisms with data available. Licarin B, a nitric oxide production inhibitor extracted from the component of the seeds of Myristica fragrans, improves insulin sensitivity via PPARγ and activation of GLUT4 in the IRS-1/PI3K/AKT pathway[1][2][3]. Licarin B, a nitric oxide production inhibitor extracted from the component of the seeds of Myristica fragrans, improves insulin sensitivity via PPARγ and activation of GLUT4 in the IRS-1/PI3K/AKT pathway[1][2][3]. Licarin B, a nitric oxide production inhibitor extracted from the component of the seeds of Myristica fragrans, improves insulin sensitivity via PPARγ and activation of GLUT4 in the IRS-1/PI3K/AKT pathway[1][2][3]. Licarin B, a nitric oxide production inhibitor extracted from the component of the seeds of Myristica fragrans, improves insulin sensitivity via PPARγ and activation of GLUT4 in the IRS-1/PI3K/AKT pathway[1][2][3].
5,7-dihydroxy-8-(3-methylbut-2-enyl)-2-phenyl-2,3-dihydrochromen-4-one
7-hydroxy-2-[4-hydroxy-3-(3-methylbut-2-enyl)phenyl]-2,3-dihydrochromen-4-one
(E)-1-(2,4-dihydroxyphenyl)-3-[4-(3-methylbut-2-enoxy)phenyl]prop-2-en-1-one
Isobavachalcone
Isobavachalcone (Corylifolinin) is derived from Psoralea corylifolia Linn. and is a potent inhibitor of Akt signaling pathway, which induces apoptosis in human cancer cells (Inhibits OVCAR-8 cell growth with an IC50 value of 7.92 μM). Isobavachalcone also induces Reactive Oxyen Species (ROS) generation in OVCAR-8 cells and has exhibit cancer anti-promotive and anti-proliferative activity[1]. Isobavachalcone (Corylifolinin) is derived from Psoralea corylifolia Linn. and is a potent inhibitor of Akt signaling pathway, which induces apoptosis in human cancer cells (Inhibits OVCAR-8 cell growth with an IC50 value of 7.92 μM). Isobavachalcone also induces Reactive Oxyen Species (ROS) generation in OVCAR-8 cells and has exhibit cancer anti-promotive and anti-proliferative activity[1]. Isobavachalcone (Corylifolinin) is derived from Psoralea corylifolia Linn. and is a potent inhibitor of Akt signaling pathway, which induces apoptosis in human cancer cells (Inhibits OVCAR-8 cell growth with an IC50 value of 7.92 μM). Isobavachalcone also induces Reactive Oxyen Species (ROS) generation in OVCAR-8 cells and has exhibit cancer anti-promotive and anti-proliferative activity[1].
C20H20O4_6H-Benzofuro[3,2-c][1]benzopyran-3,9-diol, 6a,11a-dihydro-2-(3-methyl-2-buten-1-yl)-, (6aR,11aR)
C20H20O4_1,3-Benzenediol, 4-[3,4,8,9-tetrahydro-8-(1-methylethenyl)-2H-furo[2,3-h]-1-benzopyran-3-yl]
prazepam
D002492 - Central Nervous System Depressants > D014149 - Tranquilizing Agents > D014151 - Anti-Anxiety Agents D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D014149 - Tranquilizing Agents N - Nervous system > N05 - Psycholeptics > N05B - Anxiolytics > N05BA - Benzodiazepine derivatives C78272 - Agent Affecting Nervous System > C29756 - Sedative and Hypnotic > C1012 - Benzodiazepine D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants D018377 - Neurotransmitter Agents > D018682 - GABA Agents > D018757 - GABA Modulators C78272 - Agent Affecting Nervous System > C28197 - Antianxiety Agent
(E)-1-(2,4-dihydroxyphenyl)-3-[4-(3-methylbut-2-enoxy)phenyl]prop-2-en-1-one
4-(8-prop-1-en-2-yl-3,4,8,9-tetrahydro-2H-furo[2,3-h]chromen-3-yl)benzene-1,3-diol
acetohexamide
A - Alimentary tract and metabolism > A10 - Drugs used in diabetes > A10B - Blood glucose lowering drugs, excl. insulins > A10BB - Sulfonylureas C78276 - Agent Affecting Digestive System or Metabolism > C29711 - Anti-diabetic Agent > C97936 - Sulfonylurea Antidiabetic Agent D007004 - Hypoglycemic Agents CONFIDENCE standard compound; INTERNAL_ID 894; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4168; ORIGINAL_PRECURSOR_SCAN_NO 4165 CONFIDENCE standard compound; INTERNAL_ID 894; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4170; ORIGINAL_PRECURSOR_SCAN_NO 4165 CONFIDENCE standard compound; INTERNAL_ID 894; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4125; ORIGINAL_PRECURSOR_SCAN_NO 4121 CONFIDENCE standard compound; INTERNAL_ID 894; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4143; ORIGINAL_PRECURSOR_SCAN_NO 4140 CONFIDENCE standard compound; INTERNAL_ID 894; DATASET 20200303_ENTACT_RP_MIX506; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4151; ORIGINAL_PRECURSOR_SCAN_NO 4150 ORIGINAL_PRECURSOR_SCAN_NO 4163; CONFIDENCE standard compound; INTERNAL_ID 894; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4165 CONFIDENCE standard compound; INTERNAL_ID 894; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4165; ORIGINAL_PRECURSOR_SCAN_NO 4163 CONFIDENCE standard compound; INTERNAL_ID 894; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8394; ORIGINAL_PRECURSOR_SCAN_NO 8389 CONFIDENCE standard compound; INTERNAL_ID 894; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8413; ORIGINAL_PRECURSOR_SCAN_NO 8409 CONFIDENCE standard compound; INTERNAL_ID 894; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8458; ORIGINAL_PRECURSOR_SCAN_NO 8454 CONFIDENCE standard compound; INTERNAL_ID 894; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8489; ORIGINAL_PRECURSOR_SCAN_NO 8485 CONFIDENCE standard compound; INTERNAL_ID 894; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8471; ORIGINAL_PRECURSOR_SCAN_NO 8468
4-(8-prop-1-en-2-yl-3,4,8,9-tetrahydro-2H-furo[2,3-h]chromen-3-yl)benzene-1,3-diol_major
Bualta
1,1,3-TRIMETHYL-3-PHENYLINDAN-4,5-DICARBOXYLIC ACID
2-Piperazinyl-4-amino-6,7-dimethoxyquinazoline hydrochloride
6-(3-Hydroxyprop-1-ynyl)-1-(4-methoxybenzyl)-1H-pyrido[2,3-b][1,4]oxazin-2(3H)-one
N-(5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDIN-3-YL)CYCLOPROPANESULFONAMIDE
Sumacetamol
C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent
Methyl 2-O-acetyl-4,6-O-benzylidene-a-D-glucopyranoside
3-BIPHENYL-4-YL-1-PHENYL-1H-PYRAZOLE-4-CARBALDEHYDE
(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 5-(2-hydroxypropan-2-yl)-2-propyl-1H-imidazole-4-carboxylate
methanesulfonic acid,2-(4-phenylmethoxyphenyl)ethanol
4-[(4-Methylpiperazin-1-yl)methyl]benzoic acid dihydrochloride
(3AR,4R,5R,6AS)-4-((E)-3,3-DIFLUORO-4-PHENOXYBUT-1-EN-1-YL)-5-HYDROXYHEXAHYDRO-2H-CYCLOPENTA[B]FURAN-2-ONE
ETHYL 1-BENZYL-4-HYDROXY-2-OXO-1,2-DIHYDRO-1,8-NAPHTHYRIDINE-3-CARBOXYLATE
Ethyl 4-hydroxy-7-methyl-2-oxo-1-phenyl-1,2-dihydro-1,8-naphthyridine-3-carboxylate
N-{4-[(1-Acetyl-4-piperidinyl)carbonyl]phenyl}methanesulfonamide
4-HYDROXY-1-METHYL-2-OXO-1,2-DIHYDRO-QUINOLINE-3-CARBOXYLIC ACID (3-METHOXY-PHENYL)-AMIDE
1,3-Bis((3-methyl-2,5-dioxopyrrol-1-yl)methyl)benzol
5,5-dimethyl-2-[[(2-phenoxyacetyl)amino]methyl]-1,3-thiazolidine-4-carboxylic acid
Des(diethylaMinoethyl)-didesiodo-1-Methoxy AMiodarone
Diethyl 2,2-(1,2-ethanediyldiimino)bis(3-sulfanylpropanoate)
1-Iodotetradecane
An organoiodine compound that is tetradecane substituted by an iodo group at position 1.
1-[4-Amino-3-chloro-5-(trifluoromethyl)phenyl]-2-(2-methylbutan-2-ylamino)ethanol
2-Amino-5-[(1-Methoxy-2-Methylindolizin-3-Yl)carbonyl]benzoic Acid
N-(3-fluorophenyl)-2-oxo-4,10-dihydro-3H-pyrimido[1,2-a]benzimidazole-4-carboxamide
6-Hydroxy-3-methyl-8-(2-phenylethyl)-2,5-dihydro-1-benzoxepine-7-carboxylic acid
7-(4-Hydroxy-3-methoxyphenyl)-1-(4-hydroxyphenyl)hepta-4,6-dien-3-one
7-Hydroxy-2-(4-hydroxyphenyl)-8-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one
5-Chloro-6-methyl-N-(2-phenylethyl)-2-pyridin-2-ylpyrimidin-4-amine
(4E)-N-(4-fluorophenyl)-4-[(phenylcarbonyl)imino]-4H-pyrazole-3-carboxamide
(2S) N-Acetyl-L-alanyl-alphal-phenylalanyl-chloroethylketone
N-[(2R)-4-diazonio-3-oxoniumylidene-1-phenylbutan-2-yl]-1-phenylmethoxymethanimidate
phaseollidin
Phaseollidin is a member of the class of compounds known as pterocarpans. Pterocarpans are benzo-pyrano-furano-benzene compounds, containing the 6H-[1]benzofuro[3,2-c]chromene skeleton. They are derivatives of isoflavonoids. Phaseollidin is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Phaseollidin can be found in a number of food items such as hyacinth bean, lima bean, yellow wax bean, and scarlet bean, which makes phaseollidin a potential biomarker for the consumption of these food products.
Stepharanine
A berberine alkaloid with formula C19H18NO4 that is isolated from several species of Stephania.
1,2,3,4-Tetrahydroquinoxalin-2,3-dione, 1-ribityl-6,7-dimethyl-
2,9-Dihydroxy-3,10-Dimethoxy-5,6-Dihydroisoquino[3,2-A]isoquinolinium
(1r,4r,5s,6s,7r,10r,11s,12s)-1,7-Bis(Hydroxymethyl)-2,8,13,14-Tetraoxatricyclo[8.2.1.1~4,7~]tetradecane-5,6,11,12-Tetrol
3,6-anhydro-alpha-L-galactopyranosyl-(1->3)-D-galactose
alpha-D-fructofuranose beta-D-fructofuranose 1,2:1,2-dianhydride
N,N-((1Z,3Z)-1,4-bis(4-hydroxyphenyl)buta-1,3-diene-2,3-diyl)diformamide
A natural product found particularly in Aspergillus fumigatus and Penicillium notatum.
N4-(3-chlorophenyl)-6-methyl-N2-(phenylmethyl)pyrimidine-2,4-diamine
2-{2,5-dimethyl-3-[(E)-(4H-1,2,4-triazol-4-ylimino)methyl]-1H-pyrrol-1-yl}-4,5-dimethylthiophene-3-carbonitrile
N-(2-fluorophenyl)-2-[3-(1-oxopropyl)-1-indolyl]acetamide
N-[4-[2-[(4-methyl-2-pyridinyl)amino]-4-thiazolyl]phenyl]acetamide
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-5,7-dimethyl-3-pyrazolo[1,5-a]pyrimidinecarboxamide
N-[3-[2-[(4-methyl-2-pyridinyl)amino]-4-thiazolyl]phenyl]acetamide
(-)-Phaseolin
A prenylated member of the class of pterocarpans and an organic heteropentacyclic compound that is 2,3,6b,12b-tetrahydro-1H,7H-chromeno[6,5:4,5]furo[3,2-c]chromen-10-ol in which both of the hydrogens at position 3 have been replaced by methyl groups (the R,R stereoisomer). It is found in found in the seeds of Phaseolus vulgaris (French bean) and in the stems of Erythrina subumbrans.
1-Phenylmethoxy-4-prop-2-enoxyquinoxaline-2,3-dione
1,3-Benzothiazol-2-yl-[4-(2-pyridinyl)-1-piperazinyl]methanone
N-[4-[2-[(6-methyl-2-pyridinyl)amino]-4-thiazolyl]phenyl]acetamide
N-[2-(4-methylphenoxy)-1-oxoethyl]-2-benzofurancarbohydrazide
2-[(4-methyl-2-oxo-1-benzopyran-7-yl)oxy]-N-(2-pyridinylmethyl)acetamide
4-Chloro-3-[[2-(4-methyl-1-piperidinyl)-1-oxoethyl]amino]benzoic acid methyl ester
6-Amino-4-(1-cyclohex-2-enyl)-3-thiophen-2-yl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
methyl N-(tert-butoxycarbonyl)-4-nitrophenylalaninate
methyl 8-[(2E)-2-[(2-chlorophenyl)methylidene]hydrazinyl]-8-oxooctanoate
alpha-N-(9-beta-D-ribofuranosylpurin-6-yl)glycinamide
alpha-D-Fructofuranose beta-D-fructopyranose 1,2:2,1-dianhydride
3,4,5-trihydroxy-6-[(E)-2-methyl-3-phenylprop-2-enoxy]oxane-2-carboxylic acid
3-(5-Hydroxy-2,2-dimethylchromen-6-yl)-1-(4-hydroxyphenyl)propan-1-one
3,4,5-trihydroxy-6-[(E)-4-phenylbut-3-en-2-yl]oxyoxane-2-carboxylic acid
S-(2,5-Diacetoxy-3,4,6-trimethyl-phenylmethyl)thioacetate
Levofuraltadona
C254 - Anti-Infective Agent > C52588 - Antibacterial Agent
bis-beta-D-fructofuranose 1,2:2,3-dianhydride
A sugar dianhydride obtained by the condensation of two units of beta-D-fructofuranose.
HMR1556
D002317 - Cardiovascular Agents > D026902 - Potassium Channel Blockers D049990 - Membrane Transport Modulators
(-)-Phaseollinisoflavan
A member of the class of hydroxyisoflavans that is (3R)-3,4-dihydro-2H,2H-3,6-bichromene substituted by two methyl groups at positions 2 and 2 and hydroxy groups at positions 5 and 7 respectively.
1-Decanoyl-sn-glycero-3-phosphate(2-)
A 1-acyl-sn-glycerol 3-phosphate(2-) obtained by deprotonation of the phosphate OH groups of 1-capryl-sn-glycero-3-phosphate.
1,4,6,7,10-pentahydroxy-3-methoxy-6-methyl-5,7,8,8a,10,10a-hexahydroanthracen-9-one
2-[(10-hydroxydeca-2,8-dien-4,6-diyn-1-yl)oxy]-6-(hydroxymethyl)oxane-3,4,5-triol
(2s)-5-hydroxy-7-[(3-methylbut-2-en-1-yl)oxy]-2-phenyl-2,3-dihydro-1-benzopyran-4-one
5-methoxy-2,2-dimethyl-6-(3-methylbuta-1,3-dien-1-yl)pyrano[2,3-h]chromen-8-one
2-(4-hydroxy-2-methoxyphenyl)-5-(3-methylbut-2-en-1-yl)-1-benzofuran-6-ol
8-(7-hydroxy-3,4-dihydro-2h-1-benzopyran-3-yl)-2,2-dimethylchromen-5-ol
5,7-dihydroxy-8-(3-methylbut-1-en-1-yl)-2-phenyl-2,3-dihydro-1-benzopyran-4-one
(2e)-1-{2,6-dihydroxy-4-[(3-methylbut-2-en-1-yl)oxy]phenyl}-3-phenylprop-2-en-1-one
(1r,10r)-15-(3-methylbut-2-en-1-yl)-8,17-dioxatetracyclo[8.7.0.0²,⁷.0¹¹,¹⁶]heptadeca-2,4,6,11(16),12,14-hexaene-5,14-diol
(2s,4r)-11-hydroxy-4-methyl-9-(2-phenylethyl)-6-oxatricyclo[5.4.0.0²,⁴]undeca-1(11),7,9-triene-10-carboxylic acid
4b,9-dihydroxy-7-methoxy-11,11-dimethyl-10h,10ah-benzo[b]fluoren-5-one
(4e,6e)-7-(4-hydroxy-3-methoxyphenyl)-1-(4-hydroxyphenyl)hepta-4,6-dien-3-one
(2r,4r,6r)-10-hydroxy-4-[(1r)-1-hydroxypropyl]-11,12-dimethoxy-3,7-dioxatricyclo[7.4.0.0²,⁶]trideca-1(9),10,12-trien-8-one
7-(2,3-dihydroxy-3-methylbutoxy)-6,8-dimethoxychromen-2-one
5-{6,7-dimethyl-2h,5h,6h,7h,8h-naphtho[2,3-d][1,3]dioxol-5-yl}-2h-1,3-benzodioxole
(2r,4s,6r)-10-hydroxy-4-(3-hydroxypropyl)-11,12-dimethoxy-3,7-dioxatricyclo[7.4.0.0²,⁶]trideca-1(9),10,12-trien-8-one
7-hydroxy-3-isopropyl-5,5,9-trimethylanthracene-1,2,6-trione
6-[9-(furan-2-yl)nona-2,4,6,8-tetraen-2-yl]-4-methoxy-3-methylpyran-2-one
4,5,6-trihydroxy-2-methyloxan-3-yl 3-(4-methoxyphenyl)prop-2-enoate
2-[3-hydroxy-5-methoxy-4-(3-methylbut-2-en-1-yl)phenyl]-1-benzofuran-6-ol
n-[2-(2',6-dihydroxy-5'-{2-[(hydroxymethylidene)amino]ethenyl}-[1,1'-biphenyl]-3-yl)ethenyl]carboximidic acid
(2s)-7-hydroxy-8-[(1z)-3-hydroxy-3-methylbut-1-en-1-yl]-2-phenyl-2,3-dihydro-1-benzopyran-4-one
5-[(1e)-prop-1-en-1-yl]-2-(2,4,6-trimethoxyphenyl)-1-benzofuran
2,3,5-trihydroxy-6-methyloxan-4-yl 3-(4-methoxyphenyl)prop-2-enoate
(2r,4s,6r)-10,13-dihydroxy-11,12-dimethoxy-4-propyl-3,7-dioxatricyclo[7.4.0.0²,⁶]trideca-1(13),9,11-trien-8-one
(2 e,8 e)-2,8-decadiene-4,6-diyne-1,10-diol 1-o-β-d-glucopyranoside
{"Ingredient_id": "HBIN005575","Ingredient_name": "(2 e,8 e)-2,8-decadiene-4,6-diyne-1,10-diol 1-o-\u03b2-d-glucopyranoside","Alias": "(2e,8 e)-2,8-decadiene-4,6-diyne-1,10-diol 1-o-\u03b2-d-glucopyranoside","Ingredient_formula": "C16H20O7","Ingredient_Smile": "C(C=CC#CC#CC=CCOC1C(C(C(C(O1)CO)O)O)O)O","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "SMIT14913","TCMID_id": "4817","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
ajuforrestine a
{"Ingredient_id": "HBIN014959","Ingredient_name": "ajuforrestine a","Alias": "NA","Ingredient_formula": "C20H20O4","Ingredient_Smile": "CC1=C(C2=CC(=O)C3=C(C4=C(C(=C3C2(CC1)C)O)OC=C4C)O)C","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "786","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
anticancer diarylheptanoid pmv70p691-010
{"Ingredient_id": "HBIN016318","Ingredient_name": "anticancer diarylheptanoid pmv70p691-010","Alias": "NA","Ingredient_formula": "C20H20O4","Ingredient_Smile": "COC1=C(C=C2CCC3C(C2=C1)C=CC(O3)C4=CC=C(C=C4)O)O","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "1393","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
avicennin
{"Ingredient_id": "HBIN017404","Ingredient_name": "avicennin","Alias": "NA","Ingredient_formula": "C20H20O4","Ingredient_Smile": "CC(=C)C=CC1=C(C2=C(C3=C1OC(=O)C=C3)OC(C=C2)(C)C)OC","Ingredient_weight": "324.4 g/mol","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "2035","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "5321265","DrugBank_id": "NA"}
bavachin
{"Ingredient_id": "HBIN017632","Ingredient_name": "bavachin","Alias": "NA","Ingredient_formula": "C20H20O4","Ingredient_Smile": "CC(=CCC1=CC2=C(C=C1O)OC(CC2=O)C3=CC=C(C=C3)O)C","Ingredient_weight": "324.4 g/mol","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "2172","TCMSP_id": "NA","TCM_ID_id": "6419","PubChem_id": "26436537","DrugBank_id": "NA"}
bidensyneoside b
{"Ingredient_id": "HBIN018480","Ingredient_name": "bidensyneoside b","Alias": "NA","Ingredient_formula": "C16H20O7","Ingredient_Smile": "CC#CC#CC#CC(CCOC1C(C(C(C(O1)CO)O)O)O)O","Ingredient_weight": "324.32 g/mol","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "2361","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "10892676","DrugBank_id": "NA"}
