Isobavachalcone (BioDeep_00000402838)
Main id: BioDeep_00000000310
natural product PANOMIX_OTCML-2023
代谢物信息卡片
化学式: C20H20O4 (324.1362)
中文名称: 异补骨脂查尔酮, 补骨脂乙素:异补骨脂配;异补骨脂查尔酮
谱图信息:
最多检出来源 not specific(not specific) 0%
Last reviewed on 2024-10-24.
Cite this Page
Isobavachalcone. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China.
https://query.biodeep.cn/s/isobavachalcone (retrieved
2025-02-01) (BioDeep RN: BioDeep_00000402838). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
分子结构信息
SMILES: CC(C)=CCc1c(O)ccc(C(=O)/C=C/c2ccc(O)cc2)c1O
InChI: InChI=1S/C20H20O4/c1-13(2)3-9-16-19(23)12-10-17(20(16)24)18(22)11-6-14-4-7-15(21)8-5-14/h3-8,10-12,21,23-24H,9H2,1-2H3/b11-6+
描述信息
Isobavachalcone (Corylifolinin) is derived from Psoralea corylifolia Linn. and is a potent inhibitor of Akt signaling pathway, which induces apoptosis in human cancer cells (Inhibits OVCAR-8 cell growth with an IC50 value of 7.92 μM). Isobavachalcone also induces Reactive Oxyen Species (ROS) generation in OVCAR-8 cells and has exhibit cancer anti-promotive and anti-proliferative activity[1].
Isobavachalcone (Corylifolinin) is derived from Psoralea corylifolia Linn. and is a potent inhibitor of Akt signaling pathway, which induces apoptosis in human cancer cells (Inhibits OVCAR-8 cell growth with an IC50 value of 7.92 μM). Isobavachalcone also induces Reactive Oxyen Species (ROS) generation in OVCAR-8 cells and has exhibit cancer anti-promotive and anti-proliferative activity[1].
Isobavachalcone (Corylifolinin) is derived from Psoralea corylifolia Linn. and is a potent inhibitor of Akt signaling pathway, which induces apoptosis in human cancer cells (Inhibits OVCAR-8 cell growth with an IC50 value of 7.92 μM). Isobavachalcone also induces Reactive Oxyen Species (ROS) generation in OVCAR-8 cells and has exhibit cancer anti-promotive and anti-proliferative activity[1].
同义名列表
4 个代谢物同义名
Isobavachalcone; Corylifolinin; Isobacachalcone; Isobavachalcone
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
69 个相关的物种来源信息
- 40948 - Angelica: LTS0205581
- 357850 - Angelica keiskei: 10.1016/0031-9422(90)85357-L
- 357850 - Angelica keiskei: 10.1016/S0304-3835(03)00466-X
- 357850 - Angelica keiskei: 10.1021/NP058080D
- 357850 - Angelica keiskei: LTS0205581
- 118889 - Anthyllis: LTS0205581
- 181246 - Anthyllis hermanniae: 10.1016/0031-9422(96)00128-8
- 181246 - Anthyllis hermanniae: LTS0205581
- 4037 - Apiaceae: LTS0205581
- 3488 - Artocarpus: LTS0205581
- 194251 - Artocarpus altilis: 10.1021/NP0600346
- 194251 - Artocarpus altilis: LTS0205581
- 194252 - Brosimum: LTS0205581
- 1835378 - Brosimum acutifolium: 10.1016/S0031-9422(99)00608-1
- 1835378 - Brosimum acutifolium: LTS0205581
- 66379 - Broussonetia: LTS0205581
- 172644 - Broussonetia papyrifera: 10.1021/NP010288L
- 172644 - Broussonetia papyrifera: LTS0205581
- 109218 - Cullen: LTS0205581
- 429560 - Cullen corylifolium: 10.1016/J.JCHROMB.2005.04.008
- 429560 - Cullen corylifolium: 10.1016/J.PHYMED.2009.05.015
- 429560 - Cullen corylifolium: 10.1021/NP50060A006
- 429560 - Cullen corylifolium: 10.1021/NP500834D
- 429560 - Cullen corylifolium: 10.1021/NP960157Y
- 429560 - Cullen corylifolium: 10.1248/CPB.53.1054
- 429560 - Cullen corylifolium: 10.3987/COM-92-6050
- 429560 - Cullen corylifolium: LTS0205581
- 106722 - Dorstenia: LTS0205581
- 3841 - Erythrina: LTS0205581
- 2590687 - Erythrina burttii: 10.1016/S0031-9422(01)00459-9
- 2590687 - Erythrina burttii: 10.1016/S0031-9422(97)00945-X
- 2590687 - Erythrina burttii: LTS0205581
- 556509 - Erythrina fusca: 10.1248/CPB.57.993
- 556509 - Erythrina fusca: LTS0205581
- 2759 - Eukaryota: LTS0205581
- 3803 - Fabaceae: LTS0205581
- 46347 - Glycyrrhiza: LTS0205581
- 49827 - Glycyrrhiza glabra L.: -
- 74614 - Glycyrrhiza inflata Bat.: -
- 74613 - Glycyrrhiza uralensis: 10.1248/CPB.33.3811
- 74613 - Glycyrrhiza uralensis: LTS0205581
- 74613 - Glycyrrhiza uralensis Fisch.: -
- 629714 - Hypericaceae: LTS0205581
- 55962 - Hypericum: LTS0205581
- 860794 - Hypericum geminiflorum: 10.1016/S0031-9422(96)00644-9
- 860794 - Hypericum geminiflorum: LTS0205581
- 53892 - Lespedeza: LTS0205581
- 701533 - Lespedeza cyrtobotrya: 10.1021/NP800535G
- 701533 - Lespedeza cyrtobotrya: LTS0205581
- 3495 - Maclura: LTS0205581
- 681456 - Maclura tinctoria: 10.1055/S-2001-10621
- 681456 - Maclura tinctoria: LTS0205581
- 3398 - Magnoliopsida: LTS0205581
- 3487 - Moraceae: 10.1007/S12272-015-0612-9
- 3487 - Moraceae: LTS0205581
- 3497 - Morus: LTS0205581
- 3498 - Morus alba: 10.1089/JMF.2014.3196
- 3498 - Morus alba: LTS0205581
- 226895 - Morus cathayana: 10.3987/COM-95-7310
- 226895 - Morus cathayana: LTS0205581
- 33090 - Plants: -
- 3615 - Polygonaceae: 10.1007/S12272-015-0612-9
- 3615 - Polygonaceae: LTS0205581
- 3896 - Sophora: LTS0205581
- 76398 - Sophora prostrata: 10.1016/0031-9422(94)00721-5
- 76398 - Sophora prostrata: LTS0205581
- 35493 - Streptophyta: LTS0205581
- 58023 - Tracheophyta: LTS0205581
- 33090 - Viridiplantae: LTS0205581
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
亚细胞结构定位 | 关联基因列表 |
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