Exact Mass: 286.029978
Exact Mass Matches: 286.029978
Found 487 metabolites which its exact mass value is equals to given mass value 286.029978,
within given mass tolerance error 0.05 dalton. Try search metabolite list with more accurate mass tolerance error
0.01 dalton.
Luteolin
Luteolin is a naturally occurring flavonoid. (PMID:17168665). The flavonoids are polyphenolic compounds found as integral components of the human diet. They are universally present as constituents of flowering plants, particularly of food plants. The flavonoids are phenyl substituted chromones (benzopyran derivatives) consisting of a 15-carbon basic skeleton (C6-C3-C6), composed of a chroman (C6-C3) nucleus (the benzo ring A and the heterocyclic ring C), also shared by the tocopherols, with a phenyl (the aromatic ring B) substitution usually at the 2-position. Different substitutions can typically occur in the rings, A and B. Several plants and spices containing flavonoid derivatives have found application as disease preventive and therapeutic agents in traditional medicine in Asia for thousands of years. The selection of a particular food plant, plant tissue or herb for its potential health benefits appears to mirror its flavonoid composition. The much lower risk of colon, prostate and breast cancers in Asians, who consume more vegetables, fruits and tea than populations in the Western hemisphere do, raises the question of whether flavonoid components mediate the protective effects of diets rich in these foodstuffs by acting as natural chemopreventive and anticancer agents. An impressive body of information exists on the antitumoral action of plant flavonoids. In vitro work has concentrated on the direct and indirect actions of flavonoids on tumor cells, and has found a variety of anticancer effects such as cell growth and kinase activity inhibition, apoptosis induction, suppression of the secretion of matrix metalloproteinases and of tumor invasive behavior. Furthermore, some studies have reported the impairment of in vivo angiogenesis by dietary flavonoids. Experimental animal studies indicate that certain dietary flavonoids possess antitumoral activity. The hydroxylation pattern of the B ring of the flavones and flavonols, such as luteolin seems to critically influence their activities, especially the inhibition of protein kinase activity and antiproliferation. The different mechanisms underlying the potential anticancer action of plant flavonoids await further elucidation. Certain dietary flavonols and flavones targeting cell surface signal transduction enzymes, such as protein tyrosine and focal adhesion kinases, and the processes of angiogenesis appear to be promising candidates as anticancer agents. Further in vivo studies of these bioactive constituents is deemed necessary in order to develop flavonoid-based anticancer strategies. In view of the increasing interest in the association between dietary flavonoids and cancer initiation and progression, this important field is likely to witness expanded effort and to attract and stimulate further vigorous investigations (PMID:16097445). Luteolin is a tetrahydroxyflavone in which the four hydroxy groups are located at positions 3, 4, 5 and 7. It is thought to play an important role in the human body as an antioxidant, a free radical scavenger, an anti-inflammatory agent and an immune system modulator as well as being active against several cancers. It has a role as an EC 2.3.1.85 (fatty acid synthase) inhibitor, an antineoplastic agent, a vascular endothelial growth factor receptor antagonist, a plant metabolite, a nephroprotective agent, an angiogenesis inhibitor, a c-Jun N-terminal kinase inhibitor, an anti-inflammatory agent, an apoptosis inducer, a radical scavenger and an immunomodulator. It is a 3-hydroxyflavonoid and a tetrahydroxyflavone. It is a conjugate acid of a luteolin-7-olate. Luteolin is a natural product found in Verbascum lychnitis, Carex fraseriana, and other organisms with data available. Luteolin is a naturally-occurring flavonoid, with potential anti-oxidant, anti-inflammatory, apoptosis-inducing and chemopreventive activities. Upon administration, luteolin scavenges free radicals, protects cells from reactive oxygen species (ROS)-induced damage and induces direct cell cycle arrest and apoptosis in tumor cells. This inhibits tumor cell proliferation and suppresses metastasis. 5,7,3,4-tetrahydroxy-flavone, one of the FLAVONES. See also: Chamomile (part of); Cannabis sativa subsp. indica top (part of); Fenugreek seed (part of). A tetrahydroxyflavone in which the four hydroxy groups are located at positions 3, 4, 5 and 7. It is thought to play an important role in the human body as an antioxidant, a free radical scavenger, an anti-inflammatory agent and an immune system modulator as well as being active against several cancers. Flavone v. widespread in plant world; found especies in celery, peppermint, rosemary, thyme and Queen Annes Lace leaves (wild carrot). Potential nutriceutical. Luteolin is found in many foods, some of which are soy bean, ginger, abalone, and swiss chard. Acquisition and generation of the data is financially supported in part by CREST/JST. IPB_RECORD: 361; CONFIDENCE confident structure CONFIDENCE standard compound; INTERNAL_ID 48 Luteolin (Luteoline), a flavanoid compound, is a potent Nrf2 inhibitor. Luteolin has anti-inflammatory, anti-cancer properties, including the induction of apoptosis and cell cycle arrest, and the inhibition of metastasis and angiogenesis, in several cancer cell lines, including human non-small lung cancer cells[1][2][3]. Luteolin (Luteoline), a flavanoid compound, is a potent Nrf2 inhibitor. Luteolin has anti-inflammatory, anti-cancer properties, including the induction of apoptosis and cell cycle arrest, and the inhibition of metastasis and angiogenesis, in several cancer cell lines, including human non-small lung cancer cells[1][2][3].
Fisetin
Fisetin is a 7-hydroxyflavonol with additional hydroxy groups at positions 3, 3 and 4. It has a role as an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor, an antioxidant, an anti-inflammatory agent, a metabolite, a plant metabolite and a geroprotector. It is a 3-hydroxyflavonoid, a 7-hydroxyflavonol and a tetrahydroxyflavone. It is a conjugate acid of a fisetin(1-). Fisetin is a natural product found in Acacia carneorum, Acacia buxifolia, and other organisms with data available. Fisetin is an orally bioavailable naturally occurring polyphenol found in many fruits and vegetables, with potential antioxidant, neuroprotective, anti-inflammatory, antineoplastic, senolytic, and longevity promoting activities. Upon administration, fisetin, as an antioxidant, scavenges free radicals, protect cells from oxidative stress, and is able to upregulate glutathione. It inhibits pro-inflammatory mediators, such as tumor necrosis factor alpha (TNF-a), interleukin-6 (IL-6), and nuclear factor kappa B (NF-kB). Fisetin promotes cellular metabolism, reduces senescence, regulates sirtuin function and may promote longevity. Fisetin also exerts anti-cancer activity by inhibiting certain signaling pathways. It also inhibits certain anti-apoptotic proteins and induces apoptosis in susceptible cells. COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials A 7-hydroxyflavonol with additional hydroxy groups at positions 3, 3 and 4. C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor C26170 - Protective Agent > C1509 - Neuroprotective Agent C26170 - Protective Agent > C275 - Antioxidant Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS 3,7,3,4-tetrahydroxyflavone, also known as 5-desoxyquercetin or fisetinidin, is a member of the class of compounds known as flavonols. Flavonols are compounds that contain a flavone (2-phenyl-1-benzopyran-4-one) backbone carrying a hydroxyl group at the 3-position. Thus, 3,7,3,4-tetrahydroxyflavone is considered to be a flavonoid lipid molecule. 3,7,3,4-tetrahydroxyflavone is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). 3,7,3,4-tetrahydroxyflavone is a bitter tasting compound found in soy bean, which makes 3,7,3,4-tetrahydroxyflavone a potential biomarker for the consumption of this food product. relative retention time with respect to 9-anthracene Carboxylic Acid is 0.847 [Raw Data] CB035_Fisetin_pos_20eV_CB000018.txt [Raw Data] CB035_Fisetin_pos_30eV_CB000018.txt [Raw Data] CB035_Fisetin_pos_40eV_CB000018.txt [Raw Data] CB035_Fisetin_pos_10eV_CB000018.txt [Raw Data] CB035_Fisetin_pos_50eV_CB000018.txt [Raw Data] CB035_Fisetin_neg_10eV_000011.txt [Raw Data] CB035_Fisetin_neg_30eV_000011.txt [Raw Data] CB035_Fisetin_neg_40eV_000011.txt [Raw Data] CB035_Fisetin_neg_20eV_000011.txt [Raw Data] CB035_Fisetin_neg_50eV_000011.txt Fisetin is a natural flavonol found in many fruits and vegetables with various benefits, such as antioxidant, anticancer, neuroprotection effects. Fisetin is a natural flavonol found in many fruits and vegetables with various benefits, such as antioxidant, anticancer, neuroprotection effects. Fisetin is a natural flavonol found in many fruits and vegetables with various benefits, such as antioxidant, anticancer, neuroprotection effects.
Kaempferol
Kaempferol is a tetrahydroxyflavone in which the four hydroxy groups are located at positions 3, 5, 7 and 4. Acting as an antioxidant by reducing oxidative stress, it is currently under consideration as a possible cancer treatment. It has a role as an antibacterial agent, a plant metabolite, a human xenobiotic metabolite, a human urinary metabolite, a human blood serum metabolite and a geroprotector. It is a member of flavonols, a 7-hydroxyflavonol and a tetrahydroxyflavone. It is a conjugate acid of a kaempferol oxoanion. Kaempferol is a natural product found in Lotus ucrainicus, Visnea mocanera, and other organisms with data available. Kaempferol is a natural flavonoid which has been isolated from Delphinium, Witch-hazel, grapefruit, and other plant sources. Kaempferol is a yellow crystalline solid with a melting point of 276-278 degree centigrade. It is slightly soluble in water, and well soluble in hot ethanol and diethyl ether. Kaempferol is a metabolite found in or produced by Saccharomyces cerevisiae. See also: Cannabis sativa subsp. indica top (part of); Tussilago farfara flower (part of). Kaempferol, also known as rhamnolutein or c.i. 75640, belongs to the class of organic compounds known as flavonols. Flavonols are compounds that contain a flavone (2-phenyl-1-benzopyran-4-one) backbone carrying a hydroxyl group at the 3-position. Thus, kaempferol is considered to be a flavonoid molecule. A tetrahydroxyflavone in which the four hydroxy groups are located at positions 3, 5, 7 and 4. Kaempferol is a very hydrophobic molecule, practically insoluble in water, and relatively neutral. Kaempferol exists in all eukaryotes, ranging from yeast to humans. Kaempferol is a bitter tasting compound. Kaempferol is found, on average, in the highest concentration within a few different foods, such as saffrons, capers, and cumins and in a lower concentration in lovages, endives, and cloves. Kaempferol has also been detected, but not quantified, in several different foods, such as shallots, pine nuts, feijoa, kombus, and chicory leaves. This could make kaempferol a potential biomarker for the consumption of these foods. Kaempferol is a potentially toxic compound. Very widespread in the plant world, e.g. in Brassicaceae, Apocynaceae, Dilleniaceae, Ranunculaceae, Leguminosae, etc. Found especies in broccoli, capers, chives, kale, garden cress, fennel, lovage, dill weed and tarragon [CCD] A tetrahydroxyflavone in which the four hydroxy groups are located at positions 3, 5, 7 and 4. Acting as an antioxidant by reducing oxidative stress, it is currently under consideration as a possible cancer treatment. CONFIDENCE standard compound; INTERNAL_ID 898; DATASET 20200303_ENTACT_RP_MIX500; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3906; ORIGINAL_PRECURSOR_SCAN_NO 3905 CONFIDENCE standard compound; INTERNAL_ID 898; DATASET 20200303_ENTACT_RP_MIX500; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3916; ORIGINAL_PRECURSOR_SCAN_NO 3915 CONFIDENCE standard compound; INTERNAL_ID 898; DATASET 20200303_ENTACT_RP_MIX500; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3928; ORIGINAL_PRECURSOR_SCAN_NO 3927 CONFIDENCE standard compound; INTERNAL_ID 898; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4291; ORIGINAL_PRECURSOR_SCAN_NO 4290 CONFIDENCE standard compound; INTERNAL_ID 898; DATASET 20200303_ENTACT_RP_MIX500; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3918; ORIGINAL_PRECURSOR_SCAN_NO 3917 CONFIDENCE standard compound; INTERNAL_ID 898; DATASET 20200303_ENTACT_RP_MIX500; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3915; ORIGINAL_PRECURSOR_SCAN_NO 3914 Acquisition and generation of the data is financially supported in part by CREST/JST. INTERNAL_ID 2358; CONFIDENCE Reference Standard (Level 1) CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 2358 CONFIDENCE standard compound; INTERNAL_ID 47 CONFIDENCE standard compound; ML_ID 45 Kaempferol (Kempferol), a flavonoid found in many edible plants, inhibits estrogen receptor α expression in breast cancer cells and induces apoptosis in glioblastoma cells and lung cancer cells by activation of MEK-MAPK. Kaempferol can be uesd for the research of breast cancer[1][2][3][4]. Kaempferol (Kempferol), a flavonoid found in many edible plants, inhibits estrogen receptor α expression in breast cancer cells and induces apoptosis in glioblastoma cells and lung cancer cells by activation of MEK-MAPK. Kaempferol can be uesd for the research of breast cancer[1][2][3][4].
Maritimetin
Maritimetin is a hydroxyaurone that is aurone substituted by hydroxy groups at positions 6, 7, 3 and 4 respectively. It has a role as a radical scavenger and a plant metabolite. It is functionally related to an aurone. Maritimetin is a natural product found in Lasthenia californica, Coreopsis tinctoria, and Bidens aurea with data available. A hydroxyaurone that is aurone substituted by hydroxy groups at positions 6, 7, 3 and 4 respectively. Maritimetin is used in flavourin
Cernuine
Aureusidin is a hydroxyaurone that is aurone substituted by hydroxy groups at positions 4, 6, 3 and 4 respectively. It has a role as a plant metabolite. It is functionally related to an aurone. It is a conjugate acid of an aureusidin-6-olate. Aureusidin is a natural product found in Eleocharis dulcis, Eleocharis pallens, and other organisms with data available. Cernuine is found in citrus. Cernuine is isolated from Citrus medica (citron). Isolated from Citrus medica (citron). Cernuine is found in lemon and citrus. Aureusidin is an aurone with high antioxidant and lipoxygenase inhibitory activity. Aureusidin also shows anti-inflammatory effects[1]. Aureusidin is an aurone with high antioxidant and lipoxygenase inhibitory activity. Aureusidin also shows anti-inflammatory effects[1]. Aureusidin is an aurone with high antioxidant and lipoxygenase inhibitory activity. Aureusidin also shows anti-inflammatory effects[1].
oxazepam
D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D006993 - Hypnotics and Sedatives D002492 - Central Nervous System Depressants > D014149 - Tranquilizing Agents > D014151 - Anti-Anxiety Agents D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D014149 - Tranquilizing Agents N - Nervous system > N05 - Psycholeptics > N05B - Anxiolytics > N05BA - Benzodiazepine derivatives C78272 - Agent Affecting Nervous System > C29756 - Sedative and Hypnotic > C1012 - Benzodiazepine D018377 - Neurotransmitter Agents > D018682 - GABA Agents > D018757 - GABA Modulators C78272 - Agent Affecting Nervous System > C28197 - Antianxiety Agent CONFIDENCE standard compound; INTERNAL_ID 799; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8781; ORIGINAL_PRECURSOR_SCAN_NO 8778 CONFIDENCE standard compound; INTERNAL_ID 799; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8746; ORIGINAL_PRECURSOR_SCAN_NO 8744 CONFIDENCE standard compound; INTERNAL_ID 799; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4409; ORIGINAL_PRECURSOR_SCAN_NO 4408 CONFIDENCE standard compound; INTERNAL_ID 799; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8712; ORIGINAL_PRECURSOR_SCAN_NO 8710 CONFIDENCE standard compound; INTERNAL_ID 799; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4423; ORIGINAL_PRECURSOR_SCAN_NO 4421 CONFIDENCE standard compound; INTERNAL_ID 799; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8742; ORIGINAL_PRECURSOR_SCAN_NO 8740 CONFIDENCE standard compound; INTERNAL_ID 799; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8757; ORIGINAL_PRECURSOR_SCAN_NO 8755 CONFIDENCE standard compound; INTERNAL_ID 799; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4422; ORIGINAL_PRECURSOR_SCAN_NO 4421 CONFIDENCE standard compound; INTERNAL_ID 799; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4393; ORIGINAL_PRECURSOR_SCAN_NO 4390 CONFIDENCE standard compound; INTERNAL_ID 799; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 8709; ORIGINAL_PRECURSOR_SCAN_NO 8708 CONFIDENCE standard compound; INTERNAL_ID 799; DATASET 20200303_ENTACT_RP_MIX508; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4374; ORIGINAL_PRECURSOR_SCAN_NO 4372 CONFIDENCE Reference Standard (Level 1); INTERNAL_ID 1083 CONFIDENCE standard compound; EAWAG_UCHEM_ID 2743 CONFIDENCE standard compound; INTERNAL_ID 8604 CONFIDENCE standard compound; INTERNAL_ID 2680
Scutellarein
Scutellarein is a natural flavonoid compound with anti-inflammatory effects. Scutellarein is a natural flavonoid compound with anti-inflammatory effects.
2'-Hydroxygenistein
Isolated from Cajanus cajan (pigeon pea), Dolichos biflorus (papadi), Lablab niger (hyacinth bean), Phaseolus vulgaris (kidney bean) and Phaseolus coccineus (scarlet runner bean). 2-Hydroxygenistein is found in many foods, some of which are pulses, walnut, saskatoon berry, and garden tomato (variety). 2-Hydroxygenistein is found in adzuki bean. 2-Hydroxygenistein is isolated from Cajanus cajan (pigeon pea), Dolichos biflorus (papadi), Lablab niger (hyacinth bean), Phaseolus vulgaris (kidney bean) and Phaseolus coccineus (scarlet runner bean).
3'-Hydroxygenistein
Orobol is a member of the class of 7-hydroxyisoflavones which consists of isoflavone substituted by hydroxy groups at positions 5, 7, 3 and 4. It has been isolated from the mycelia of Cordyceps sinensis. It has a role as an anti-inflammatory agent, a radical scavenger, a plant metabolite and a fungal metabolite. It is functionally related to an isoflavone. Orobol is a natural product found in Tritirachium, Ammopiptanthus mongolicus, and other organisms with data available. A member of the class of 7-hydroxyisoflavones which consists of isoflavone substituted by hydroxy groups at positions 5, 7, 3 and 4. It has been isolated from the mycelia of Cordyceps sinensis. 3-Hydroxygenistein is a polyphenol metabolite detected in biological fluids (PMID: 20428313). A polyphenol metabolite detected in biological fluids [PhenolExplorer]
Glycineamideribotide
Glycinamidoribotide conversion to N-formylglycinamide ribonucleotide is the third reaction of the de novo purine biosynthesis, a reaction catalyzed by the enzyme Glycinamide ribonucleotide transformylase (EC 2.1.2.2), with concomitant conversion of 10-formyltetrahydrofolate to tetrahydrofolate. (PMID: 9143358). Glycineamideribotide formation is stimulated by Luteinizing hormone (LH) and Chorionic gonadotropin (HCG) via activation of Glc-6-P-dehydrogenase (EC 1.1.1.49). (PMID: 4366083) [HMDB] Glycinamidoribotide conversion to N-formylglycinamide ribonucleotide is the third reaction of the de novo purine biosynthesis, a reaction catalyzed by the enzyme Glycinamide ribonucleotide transformylase (EC 2.1.2.2), with concomitant conversion of 10-formyltetrahydrofolate to tetrahydrofolate. (PMID: 9143358). Glycineamideribotide formation is stimulated by Luteinizing hormone (LH) and Chorionic gonadotropin (HCG) via activation of Glc-6-P-dehydrogenase (EC 1.1.1.49). (PMID: 4366083).
Citreorosein
Citreorosein is found in green vegetables. Citreorosein is found in roots of Polygonum cuspidatum (Japanese knotweed Found in roots of Polygonum cuspidatum (Japanese knotweed)
Norartocarpetin
Norartocarpetin is a member of flavones. Norartocarpetin is a natural product found in Dalbergia sissoo, Ficus formosana, and other organisms with data available. Norartocarpetin is found in fruits. Norartocarpetin is a constituent of the heartwood of Artocarpus heterophyllus (jackfruit) Constituent of the heartwood of Artocarpus heterophyllus (jackfruit). Norartocarpetin is found in jackfruit and fruits. Norartocarpetin is a tyrosinase inhibitor. Norartocarpetin has strong tyrosinase inhibitory activity with an IC50 value of 0.47 μM. Norartocarpetin as an antibrowning agent can be used for the research of food systems. Norartocarpetin also has a significant anticancer activity in lung carcinoma cells (NCI-H460) with an IC50 value of 22 μM. Norartocarpetin has antiproliferative effects are mediated via targeting Ras/Raf/MAPK signalling pathway, mitochondrial mediated apoptosis, S-phase cell cycle arrest and suppression of cell migration and invasion in human lung carcinoma cells[1][2]. Norartocarpetin is a tyrosinase inhibitor. Norartocarpetin has strong tyrosinase inhibitory activity with an IC50 value of 0.47 μM. Norartocarpetin as an antibrowning agent can be used for the research of food systems. Norartocarpetin also has a significant anticancer activity in lung carcinoma cells (NCI-H460) with an IC50 value of 22 μM. Norartocarpetin has antiproliferative effects are mediated via targeting Ras/Raf/MAPK signalling pathway, mitochondrial mediated apoptosis, S-phase cell cycle arrest and suppression of cell migration and invasion in human lung carcinoma cells[1][2].
Oxazepam
Oxazepam is only found in individuals that have used or taken this drug. It is an intermediate-acting benzodiazepine used to treat alcohol withdrawal and anxiety disorders. It is a metabolite of diazepam, prazepam, temazepam, and clorazepate, and has moderate amnesic, anxiolytic, anticonvulsant, hypnotic, sedative, and skeletal muscle relaxant properties compared to other benzodiazepines (Wikipedia). Like other benzodiazepines, oxazepam exerts its anxiolytic effects by potentiating the effect of gamma-aminobutyric acid (GABA) on GABA-A receptors through a cooperative mechanism of action. GABA receptors are ionotropic chloride-linked channel receptors that produce inhibitory postsynaptic potentials. When activated by GABA, the GABA receptor/chloride ionophore complex undergoes a conformational change that allows the passage of chloride ions through the channel. Benzodiazepines are believed to exert their effect by increasing the effect of GABA at its receptor. Benzodiazepine binding increases chloride conductance in the presence of GABA by increasing the frequency at which the channel opens. In contrast, barbiturates increase chloride conductance in the presence of GABA by prolonging the time in which the channel remains open. There are 18 subtypes of the GABA receptor subunits. The α2 subunit of the α2β3γ2 receptor complex is thought to mediate anxiolytic effects while the α1 subunit of the α1β2γ2 receptor complex is thought to mediate sedative, anticonvulsant, and anterograde amnesia effects. D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D006993 - Hypnotics and Sedatives D002492 - Central Nervous System Depressants > D014149 - Tranquilizing Agents > D014151 - Anti-Anxiety Agents D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D014149 - Tranquilizing Agents N - Nervous system > N05 - Psycholeptics > N05B - Anxiolytics > N05BA - Benzodiazepine derivatives C78272 - Agent Affecting Nervous System > C29756 - Sedative and Hypnotic > C1012 - Benzodiazepine D018377 - Neurotransmitter Agents > D018682 - GABA Agents > D018757 - GABA Modulators C78272 - Agent Affecting Nervous System > C28197 - Antianxiety Agent
norclobazam
norclobazam is a metabolite of clobazam. Clobazam (marketed under the brand names Frisium, Urbanol and Onfi), is a drug which is a benzodiazepine derivative. It has been marketed as an anxiolytic since 1975 and an anticonvulsant since 1984. (Wikipedia) D002491 - Central Nervous System Agents > D000927 - Anticonvulsants
p-Hydroxynordiazepam
p-Hydroxynordiazepam is a metabolite of clorazepate. Clorazepate (marketed under the brand names Tranxene and Novo-Clopate), also known as clorazepate dipotassium, is a drug that is a benzodiazepine derivative. It possesses anxiolytic, anticonvulsant, sedative, hypnotic and skeletal muscle relaxant properties. Clorazepate is a prodrug for desmethyldiazepam, which is rapidly produced as an active metabolite. Desmethyldiazepam is responsible for most of the therapeutic effects of clorazepate. (Wikipedia)
Uralenneoside
Uralenneoside is found in herbs and spices. Uralenneoside is a constituent of the leaves of Glycyrrhiza uralensis (Chinese licorice). Constituent of the leaves of Glycyrrhiza uralensis (Chinese licorice). Uralenneoside is found in herbs and spices.
3,5,6,7-tetrahydroxy-2-(4-hydroxyphenyl)-1λ⁴-chromen-1-ylium
5,6,7,4'-Tetrahydroxyisoflavone
5,6,7,4-Tetrahydroxyisoflavone is a polyphenol metabolite detected in biological fluids (PMID: 20428313). A polyphenol metabolite detected in biological fluids [PhenolExplorer]
3'-Methoxyfukiic acid
3-Methoxyfukiic acid is found in green vegetables. 3-Methoxyfukiic acid is isolated from Petasites japonicus (sweet coltsfoot
7,8,3',4'-Tetrahydroxyisoflavone
7,8,3,4-Tetrahydroxyisoflavone is a polyphenol metabolite detected in biological fluids (PMID: 20428313). A polyphenol metabolite detected in biological fluids [PhenolExplorer]
Demoxepam
Demoxepam belongs to the family of Benzodiazepines. These are organic compounds containing a benzene ring fused to either isomers of diazepine(unsaturated seven-member heterocycle with two nitrogen atoms replacing two carbon atoms).
Diphenol glucuronide
Diphenol glucuronide belongs to the family of Glucuronides. These are compounds comprising the glucuronic acid linked to another substance via a glycosidic bond.
Methyl 2-(1H-indole-3-carbonyl)thiazole-4-carboxylate
C14H10N2O3S (286.04121100000003)
Fenclorac
C14H16Cl2O2 (286.05272959999996)
C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic C471 - Enzyme Inhibitor > C1323 - Cyclooxygenase Inhibitor
Imirestat
C471 - Enzyme Inhibitor > C72880 - Aldose Reductase Inhibitor
8-Hydroxygenistein
8-hydroxygenistein is a member of the class of compounds known as isoflavones. Isoflavones are polycyclic compounds containing a 2-isoflavene skeleton which bears a ketone group at the C4 carbon atom. 8-hydroxygenistein is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). 8-hydroxygenistein can be found in a number of food items such as scarlet bean, mung bean, lima bean, and adzuki bean, which makes 8-hydroxygenistein a potential biomarker for the consumption of these food products.
Scutellarein
Scutellarein is flavone substituted with hydroxy groups at C-4, -5, -6 and -7. It has a role as a metabolite. It is functionally related to an apigenin. It is a conjugate acid of a scutellarein(1-). Scutellarein is a natural product found in Scoparia dulcis, Artemisia douglasiana, and other organisms with data available. Flavone substituted with hydroxy groups at C-4, -5, -6 and -7. Scutellarein, also known as 6-hydroxyapigenin or 4,5,6,7-tetrahydroxyflavanone, is a member of the class of compounds known as flavones. Flavones are flavonoids with a structure based on the backbone of 2-phenylchromen-4-one (2-phenyl-1-benzopyran-4-one). Thus, scutellarein is considered to be a flavonoid lipid molecule. Scutellarein is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Scutellarein can be synthesized from apigenin. Scutellarein is also a parent compound for other transformation products, including but not limited to, scutellarin, 4,6-dihydroxy-5,7-dimethoxyflavone, and 6-hydroxy-4,5,7-trimethoxyflavone. Scutellarein is a bitter tasting compound found in mexican oregano and sweet orange, which makes scutellarein a potential biomarker for the consumption of these food products. Scutellarein is a flavone that can be found in Scutellaria lateriflora and other members of the genus Scutellaria, as well as the fern Asplenium belangeri . Scutellarein is a natural flavonoid compound with anti-inflammatory effects. Scutellarein is a natural flavonoid compound with anti-inflammatory effects.
Luteolin
Annotation level-1 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.976 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.975 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.968 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.971 Luteolin (Luteoline), a flavanoid compound, is a potent Nrf2 inhibitor. Luteolin has anti-inflammatory, anti-cancer properties, including the induction of apoptosis and cell cycle arrest, and the inhibition of metastasis and angiogenesis, in several cancer cell lines, including human non-small lung cancer cells[1][2][3]. Luteolin (Luteoline), a flavanoid compound, is a potent Nrf2 inhibitor. Luteolin has anti-inflammatory, anti-cancer properties, including the induction of apoptosis and cell cycle arrest, and the inhibition of metastasis and angiogenesis, in several cancer cell lines, including human non-small lung cancer cells[1][2][3].
Isoscutellarein
A tetrahydroxyflavone that is apigenin with an extra hydroxy group at position 8.
Swartziol
Kaempferol (Kempferol), a flavonoid found in many edible plants, inhibits estrogen receptor α expression in breast cancer cells and induces apoptosis in glioblastoma cells and lung cancer cells by activation of MEK-MAPK. Kaempferol can be uesd for the research of breast cancer[1][2][3][4]. Kaempferol (Kempferol), a flavonoid found in many edible plants, inhibits estrogen receptor α expression in breast cancer cells and induces apoptosis in glioblastoma cells and lung cancer cells by activation of MEK-MAPK. Kaempferol can be uesd for the research of breast cancer[1][2][3][4].
Norartocarpetin
Norartocarpetin is a tyrosinase inhibitor. Norartocarpetin has strong tyrosinase inhibitory activity with an IC50 value of 0.47 μM. Norartocarpetin as an antibrowning agent can be used for the research of food systems. Norartocarpetin also has a significant anticancer activity in lung carcinoma cells (NCI-H460) with an IC50 value of 22 μM. Norartocarpetin has antiproliferative effects are mediated via targeting Ras/Raf/MAPK signalling pathway, mitochondrial mediated apoptosis, S-phase cell cycle arrest and suppression of cell migration and invasion in human lung carcinoma cells[1][2]. Norartocarpetin is a tyrosinase inhibitor. Norartocarpetin has strong tyrosinase inhibitory activity with an IC50 value of 0.47 μM. Norartocarpetin as an antibrowning agent can be used for the research of food systems. Norartocarpetin also has a significant anticancer activity in lung carcinoma cells (NCI-H460) with an IC50 value of 22 μM. Norartocarpetin has antiproliferative effects are mediated via targeting Ras/Raf/MAPK signalling pathway, mitochondrial mediated apoptosis, S-phase cell cycle arrest and suppression of cell migration and invasion in human lung carcinoma cells[1][2].
Ac-3-[5-(2-Thienylethynyl)-2-thienyl]-2-propyn-1-ol
Kaempferol
Annotation level-3 Annotation level-1 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.010 relative retention time with respect to 9-anthracene Carboxylic Acid is 1.011 Acquisition and generation of the data is financially supported by the Max-Planck-Society IPB_RECORD: 2141; CONFIDENCE confident structure IPB_RECORD: 3341; CONFIDENCE confident structure IPB_RECORD: 3321; CONFIDENCE confident structure CONFIDENCE confident structure; IPB_RECORD: 3321 IPB_RECORD: 141; CONFIDENCE confident structure Kaempferol (Kempferol), a flavonoid found in many edible plants, inhibits estrogen receptor α expression in breast cancer cells and induces apoptosis in glioblastoma cells and lung cancer cells by activation of MEK-MAPK. Kaempferol can be uesd for the research of breast cancer[1][2][3][4]. Kaempferol (Kempferol), a flavonoid found in many edible plants, inhibits estrogen receptor α expression in breast cancer cells and induces apoptosis in glioblastoma cells and lung cancer cells by activation of MEK-MAPK. Kaempferol can be uesd for the research of breast cancer[1][2][3][4].
1,3,5,8-tetrahydroxy-2-methylanthracene-9,10-dione
2-methoxy-6-[5-(prop-1-yn-1-yl)-2-thienyl]-hexa-3,5-diyn-1-yl acetate
3-alpha-L-arabinopyranosyloxy-4-hydroxybenzoic acid
6,8-dihydroxy-3-methyl-9-oxo-9h-xanthene-1-carboxylic acid
1,2,4,5-Tetrahydroxy-3-methylanthracene-9,10-dione
ASPHODELIN A
A hydroxycoumarin that is 4,7-dihydroxy-2H-chromen-2-one substituted by a 2,4-dihydroxyphenyl group at position 3. It is isolated from the roots of Asphodelus microcarpus and exhibits antimicrobial activity against bacteria like Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa and fungal microorganisms like Candida albicans and Botrytis cinerea.
2-(2,4-dihydroxyphenyl)-3,7-dihydroxychromen-4-one
1-Acetoxymethyl-8-hydroxynaphtho[2,3-c]furan-4,9-dione
1,3,4,5-Tetrahydroxy-2-methylanthracene-9,10-dione
3-Hydroxymorindone
3-Hydroxymorindone is a natural product found in Pentas suswaensis and Morinda citrifolia with data available.
2-hydroxyvertixanthone
A member of the class of xanthones that is methyl 9H-xanthene-1-carboxylate substituted by hydroxy groups at positions 2 and 8 and an oxo group at position 9. It has been isolated from Chaetomium globosum.
1,3,8-Trihydroxy-2-(hydroxymethyl)-9,10-dihydroanthracene-9,10-dione
2'-Hydroxygenistein
2-hydroxygenistein is a hydroxyisoflavone that is genistein substituted by an additional hydroxy group at position 2. It has been isolated from Crotalaria lachnophora. It has a role as a plant metabolite. It is functionally related to a genistein. It is a conjugate acid of a 2-hydroxygenistein(1-). 2-Hydroxygenistein is a natural product found in Crotalaria lachnophora, Vigna radiata, and other organisms with data available. Isolated from Cajanus cajan (pigeon pea), Dolichos biflorus (papadi), Lablab niger (hyacinth bean), Phaseolus vulgaris (kidney bean) and Phaseolus coccineus (scarlet runner bean). 2-Hydroxygenistein is found in many foods, some of which are pulses, walnut, saskatoon berry, and garden tomato (variety). 2-Hydroxygenistein is found in adzuki bean. 2-Hydroxygenistein is isolated from Cajanus cajan (pigeon pea), Dolichos biflorus (papadi), Lablab niger (hyacinth bean), Phaseolus vulgaris (kidney bean) and Phaseolus coccineus (scarlet runner bean). A hydroxyisoflavone that is genistein substituted by an additional hydroxy group at position 2. It has been isolated from Crotalaria lachnophora.
2,5,6,7-tetrahydroxyflavone
5,7,2,6-Tetrahydroxyflavone is a natural product found in Scutellaria amoena, Andrographis macrobotrys, and other organisms with data available.
6-CHLOROPURINE RIBOSIDE
relative retention time with respect to 9-anthracene Carboxylic Acid is 0.348 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.349 relative retention time with respect to 9-anthracene Carboxylic Acid is 0.343
2-(3,4-dihydroxyphenyl)-5,7-dihydroxychromen-4-one
3,5,7-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one
3,8-dihydroxy-6-methyl-9-oxoxanthene-1-carboxylic acid
Norclobazam
D002491 - Central Nervous System Agents > D000927 - Anticonvulsants
3,8-dihydroxy-6-methyl-9-oxoxanthene-1-carboxylic acid [IIN-based on: CCMSLIB00000847899]
3,8-dihydroxy-6-methyl-9-oxoxanthene-1-carboxylic acid [IIN-based: Match]
2,2-dimethyl-8-(phenylthio)-4H-benzo[d][1,3]dioxin-4-one
Aureusidin
Aureusidin is a hydroxyaurone that is aurone substituted by hydroxy groups at positions 4, 6, 3 and 4 respectively. It has a role as a plant metabolite. It is functionally related to an aurone. It is a conjugate acid of an aureusidin-6-olate. Aureusidin is a natural product found in Eleocharis dulcis, Eleocharis pallens, and other organisms with data available. A hydroxyaurone that is aurone substituted by hydroxy groups at positions 4, 6, 3 and 4 respectively. Aureusidin is an aurone with high antioxidant and lipoxygenase inhibitory activity. Aureusidin also shows anti-inflammatory effects[1]. Aureusidin is an aurone with high antioxidant and lipoxygenase inhibitory activity. Aureusidin also shows anti-inflammatory effects[1]. Aureusidin is an aurone with high antioxidant and lipoxygenase inhibitory activity. Aureusidin also shows anti-inflammatory effects[1].
Sulfametrole
C254 - Anti-Infective Agent > C29739 - Sulfonamide Anti-Infective Agent D000890 - Anti-Infective Agents > D013424 - Sulfanilamides
Germane, [5-(diethoxymethyl)-2-furanyl]trimethyl
C12H22GeO3 (286.07896619999997)
6-chloro-4-phenyl-1,4-dihydroquinazoline-2-carboxylic acid
3-bromo-2-tert-butyl-6-chloroimidazo[1,2-a]pyridine
4-CHLORO-6-(THIAZOL-2-YLCARBAMOYL)-CYCLOHEX-3-ENECARBOXYLIC ACID
Tauromustine
C274 - Antineoplastic Agent > C186664 - Cytotoxic Chemotherapeutic Agent > C2842 - DNA Binding Agent D000970 - Antineoplastic Agents
Olprinone hydrochloride
D004791 - Enzyme Inhibitors > D010726 - Phosphodiesterase Inhibitors > D058987 - Phosphodiesterase 3 Inhibitors D020011 - Protective Agents > D002316 - Cardiotonic Agents D002317 - Cardiovascular Agents
2-FLUORO-2-METHANESULFONYLOXYMETHYL-MALONIC ACID DIETHYL ESTER
4-Bromo-1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
C10H16BBrN2O2 (286.04881259999996)
1-methyl-5-phenoxy-3-(trifluoromethyl)pyrazole-4-carboxylic acid
C12H9F3N2O3 (286.05652399999997)
1-(5-Bromo-3-nitropyridin-2-yl)piperazine
C9H11BrN4O2 (286.00653259999996)
3-Bromo-2-isopropoxy-5-formylphenylboronic acid
C10H12BBrO4 (286.00119620000004)
2-BROMO-5-METHOXY-BENZENEPROPANOIC ACID ETHYL ESTER
(4-METHOXY-BENZYL)-PYRIDIN-3-YL-AMINE DIHYDROCHLORIDE
C13H16Cl2N2O (286.06396259999997)
3-chloro-9,10-dihydro-9,10-dioxoanthracene-2-carboxylic acid
5-METHYL-2-(4-TRIFLUOROMETHOXYPHENYL)-3H-IMIDAZOLE-4-CARBOXYLIC ACID
C12H9F3N2O3 (286.05652399999997)
1,3-bis-(Chloropropyl)tetramethyldisiloxane
C10H24Cl2OSi2 (286.07426739999994)
3 5-dimethoxyphenyl trifluoromethanesul&
C9H9F3O5S (286.01227800000004)
(2,5-dioxopyrrolidin-1-yl) 6-hydrazinylpyridine-3-carboxylate,hydrochloride
2-[4-(5-bromopyrimidin-2-yl)piperazin-1-yl]ethanol
5-Bromo-2-(4-morpholinyl)-3-pyridinecarboxylic acid
C10H11BrN2O3 (285.99529959999995)
3-bromo-5-nitro-N-propylbenzamide
C10H11BrN2O3 (285.99529959999995)
3-Bromo-N-isopropyl-5-nitrobenzamide
C10H11BrN2O3 (285.99529959999995)
Phosphoric acid, octyl ester, potassium salt
C8H17K2O4P (286.01385719999996)
2-CHLOROMETHYL-5-METHYL-4-OXO-3,4-DIHYDRO-THIENO[2,3-D]PYRIMIDINE-6-CARBOXYLIC ACID ETHYL ESTER
5,5,8,8-TETRAMETHYL-5,6,7,8-TETRAHYDRO-2-NAPHTHALENESULFONYL CHLORIDE
2-[[2-(benzylsulfonylamino)acetyl]amino]acetate
C11H14N2O5S (286.06233940000004)
3-[(4-acetamidophenyl)sulfonylamino]propanoic acid
C11H14N2O5S (286.06233940000004)
4-[(1-phenyl-1H-tetrazol-5-yl)thio]pyrocatechol
C13H10N4O2S (286.05244400000004)
1-(3,4-DICHLOROPHENYL)-4-OXOCYCLOHEXANECARBOXYLIC ACID
C13H12Cl2O3 (286.01634620000004)
4-(BENZYLOXY)BENZENE-1,2-DIAMINE DIHYDROCHLORIDE
C13H16Cl2N2O (286.06396259999997)
[5,5-Bipyrimidine]-2,2,4,4,6,6(1H,1H,3H,3H,5H,5H)-hexone,5,5-dihydroxy-
4-(2-Bromo-4-nitrophenyl)morpholine
C10H11BrN2O3 (285.99529959999995)
6-methoxy-2-(4-nitrophenyl)-1,3-benzothiazole
C14H10N2O3S (286.04121100000003)
Sodium carbonate decahydrate
C78275 - Agent Affecting Blood or Body Fluid > C29730 - Electrolyte Replacement Agent
CARBAMIC ACID, (5-BROMO-4-METHYL-2-PYRIDINYL)-,1,1-DIMETHYLETHYL ESTER
1-(PHENYLSULFONYL)-1H-PYRROLO[3,2-C]PYRIDINE-2-CARBALDEHYDE
C14H10N2O3S (286.04121100000003)
4-Bromophenoxy t-Butyl-Dimethylsilane
C12H19BrOSi (286.03884639999995)
tert-butyl 2-(4-chlorophenyl)sulfanyl-2-methylpropanoate
4-BROMO-10,11-DIHYDRO-DIBENZO[A,D]CYCLOHEPTEN-5-ONE
5-ethyl-5-[[methoxy(methyl)phosphoryl]oxymethyl]-2-methyl-1,3,2λ5-dioxaphosphinane 2-oxide
1H-PYRROLO[2,3-B]PYRIDINE, 3-METHYL-1-[(4-METHYLPHENYL)SULFONYL]-
1-(PHENYLSULFONYL)-1H-PYRROLO[2,3-B]PYRIDINE-3-CARBALDEHYDE
C14H10N2O3S (286.04121100000003)
3-Cyano-N,N-dimethyl-6-nitro-4-oxo-1,4-dihydro-8-quinolinecarboxa mide
4-chloro-1-[(4-chlorophenoxy)methyl]pyrazole-3-carboxylic acid
Thieno[3,4-b]-1,4-dioxin-5,7-dicarboxylic acid, 2,3-dihydro-, diethyl ester
C12H14O6S (286.05110640000004)
5-bromo-3-tert-butyl-2-hydroxy-6-methylbenzoic acid
2-mercapto-6-thien-2-yl-4-(trifluoromethyl)-pyridine-3-carbonitrile
C11H5F3N2S2 (285.98462459999996)
(5ALPHA,17BETA)-N-(2-HYDROXY-1,1-DIMETHYLETHYL)-3-OXO-4-AZAANDROST-1-ENE-17-CARBOXAMIDE
4-chloro-6-methoxy-2-(trifluoromethyl)quinoline-3-carbonitrile
4-methoxy-6-methyl-5-nitro-2-(trifluoromethyl)quinoline
C12H9F3N2O3 (286.05652399999997)
6-chloro-4-phenyl-1,2-dihydroquinazoline-2-carboxylic acid
(4,6-DIMETHYL-PYRIMIDIN-2-YLSULFANYL)-PHENYL-ACETICACID
C11H14N2O5S (286.06233940000004)
3-(BENZO[D]THIAZOL-2-YL)-4,5,6,7-TETRAHYDROBENZO[B]THIOPHEN-2-AMINE
2-(5-chloro-2-methoxyphenyl)-4-pyridin-2-yl-1,3-oxazole
2 6-dimethoxyphenyl trifluoromethanesul&
C9H9F3O5S (286.01227800000004)
1-(4-methoxyphenyl)-5-(trifluoromethyl)pyrazole-4-carboxylic acid
C12H9F3N2O3 (286.05652399999997)
(3-BROMOPHENOXY)(TERT-BUTYL)DIMETHYLSILANE
C12H19BrOSi (286.03884639999995)
5-(benzenesulfonyl)-2-methylsulfanyl-1,3-thiazol-4-amine
C10H10N2O2S3 (285.99044000000004)
1-(4-Chloro-1H-pyrrolo[2,3-b]pyridin-5-yl)-2-phenoxyethanone
5-(AMINOSULFONYL)-2-MORPHOLIN-4-YLBENZOIC ACID
C11H14N2O5S (286.06233940000004)
5-(3-fluoro-4-methylsulfonylphenyl)-4-methyl-1,3-thiazol-2-amine
C11H11FN2O2S2 (286.02459580000004)
4-(furan-2-ylmethyl)-2,3-dihydro-1H-quinoxaline
C13H16Cl2N2O (286.06396259999997)
3-ethyl-5-[(3-methylthiazolidin-2-ylidene)ethylidene]rhodanine
tert-Butyl (5-bromo-3-methylpyridin-2-yl)carbamate
Brallobarbital
C10H11BrN2O3 (285.99529959999995)
C78272 - Agent Affecting Nervous System > C29756 - Sedative and Hypnotic > C67084 - Barbiturate
Benzyl 4-chloro-1H-pyrrolo[2,3-b]pyridine-5-carboxylate
1H-PYRROLO[2,3-B]PYRIDINE, 2-METHYL-1-[(4-METHYLPHENYL)SULFONYL]-
1H-PYRROLO[2,3-B]PYRIDINE, 5-METHYL-1-[(4-METHYLPHENYL)SULFONYL]-
methyl 3-bromo-4-[(2-methylpropan-2-yl)oxy]benzoate
3-Cyclopentyl-2-(3,4-dichlorophenyl)propanoic acid
C14H16Cl2O2 (286.05272959999996)
tert-butyl N-[6-(bromomethyl)pyridin-2-yl]carbamate
Tris(2-carboxyethyl)phosphine Hydrochloride
C9H16ClO6P (286.03729960000004)
3-BROMO-2-BUTOXY-5-METHYLPHENYLBORONIC &
C11H16BBrO3 (286.03757959999996)
2-[3,5-bis(trifluoromethyl)phenyl]-N-hydroxyethanimidamide
2,2,3,3-tetrafluoropropyl 4-toluenesulfonate
C10H10F4O3S (286.02867580000003)
sodium,formaldehyde,2-hydroxybenzenesulfonate,urea
5-(4-METHOXYPHENYL)-2-(TRIFLUOROMETHYL)-3-FUROIC ACID
4-(3,5-dichlorophenyl)-6-methylsulfanyl-1,3,5-triazin-2-amine
6-(4-fluorophenyl)-4-methylsulfanylpyrido[3,2-d]pyrimidin-2-amine
C14H11FN4S (286.06884180000003)
Ferrocene,(3-carboxy-1-oxopropyl)-
C14H14FeO3 (286.02922839999997)
methyl 4-fluoro-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzoate
2-Propanesulfinamide, N-[1-(2-fluoro-5-nitrophenyl)ethylidene]-2-methyl-
2-Propanesulfinamide, N-[1-(2-fluoro-5-nitrophenyl)ethylidene]-2-methyl-, [N(E),S(R)]-
Glycine,N-[(4-methylphenyl)sulfonyl]glycyl-
C11H14N2O5S (286.06233940000004)
4(1H)-Quinazolinone,3-(3-fluoro-4-methylphenyl)-2,3-dihydro-2-thioxo-
2-(3,5-Dichloro-4-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepine-2-thione
1,4,5,8-Naphthalenetetracarboxylic acid 1,8-monoanhydride
methyl (Z)-5-chloro-5-(4-chlorophenyl)-3-hydroxy-2-methylidenepent-4-enoate
C13H12Cl2O3 (286.01634620000004)
methyl (Z)-5-chloro-5-(3-chlorophenyl)-3-hydroxy-2-methylidenepent-4-enoate
C13H12Cl2O3 (286.01634620000004)
2-[2-fluoro-4-[(2-methylpropan-2-yl)oxycarbonyl]phenyl]sulfanylacetic acid
8-BROMO-7-ETHYL-1,3-DIMETHYL-2,3,6,7-TETRAHYDRO-1H-PURINE-2,6-DIONE
C9H11BrN4O2 (286.00653259999996)
methyl 4-phenyl-5-(trifluoromethyl)thiophene-2-carboxylate
7-chloro-5-phenyl-2-thioxo-2,3-dihydro-1h-1,4-benzodiazepine
4,6-dichloro-2-methyl-5-(1-acetyl-2-imidazolin-2-yl)-aminopyridine
2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-5-(4-hydroxyphenyl)-
2-(4-Nitro-benzylsulfanyl)-benzooxazole
C14H10N2O3S (286.04121100000003)
N-[(E)-(4-hydroxy-3-nitrophenyl)methylidene]pyridine-4-carbohydrazide
3-[(3-Fluorophenyl)methylthio]-6-(2-furanyl)pyridazine
3,8-Dihydroxy-6-methyl-9-oxo-9H-xanthene-1-carboxylic acid
2-Amino-6-(3,5-dimethylphenyl)sulfonylbenzonitrile
3-deoxy-3-fluoro-D-erythro-alpha-L-manno-non-2-ulopyranosonic acid
Fenclorac
C14H16Cl2O2 (286.05272959999996)
C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic C471 - Enzyme Inhibitor > C1323 - Cyclooxygenase Inhibitor
Flavonoid
Scutellarein is a natural flavonoid compound with anti-inflammatory effects. Scutellarein is a natural flavonoid compound with anti-inflammatory effects.
520-30-9
Norartocarpetin is a tyrosinase inhibitor. Norartocarpetin has strong tyrosinase inhibitory activity with an IC50 value of 0.47 μM. Norartocarpetin as an antibrowning agent can be used for the research of food systems. Norartocarpetin also has a significant anticancer activity in lung carcinoma cells (NCI-H460) with an IC50 value of 22 μM. Norartocarpetin has antiproliferative effects are mediated via targeting Ras/Raf/MAPK signalling pathway, mitochondrial mediated apoptosis, S-phase cell cycle arrest and suppression of cell migration and invasion in human lung carcinoma cells[1][2]. Norartocarpetin is a tyrosinase inhibitor. Norartocarpetin has strong tyrosinase inhibitory activity with an IC50 value of 0.47 μM. Norartocarpetin as an antibrowning agent can be used for the research of food systems. Norartocarpetin also has a significant anticancer activity in lung carcinoma cells (NCI-H460) with an IC50 value of 22 μM. Norartocarpetin has antiproliferative effects are mediated via targeting Ras/Raf/MAPK signalling pathway, mitochondrial mediated apoptosis, S-phase cell cycle arrest and suppression of cell migration and invasion in human lung carcinoma cells[1][2].
Viset
COVID info from clinicaltrial, clinicaltrials, clinical trial, clinical trials C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor C26170 - Protective Agent > C1509 - Neuroprotective Agent C26170 - Protective Agent > C275 - Antioxidant Corona-virus Coronavirus SARS-CoV-2 COVID-19 SARS-CoV COVID19 SARS2 SARS Fisetin is a natural flavonol found in many fruits and vegetables with various benefits, such as antioxidant, anticancer, neuroprotection effects. Fisetin is a natural flavonol found in many fruits and vegetables with various benefits, such as antioxidant, anticancer, neuroprotection effects. Fisetin is a natural flavonol found in many fruits and vegetables with various benefits, such as antioxidant, anticancer, neuroprotection effects.
4-(3,5,7-Trihydroxy-2H-1-benzopyran-2-ylidene)-2-hydroxy-2,5-cyclohexadiene-1-one
1,2,3,8-Tetrahydroxy-7-methylanthracene-9,10-dione
[[2-(1H-indol-3-yl)ethanethioyl]amino] hydrogen sulfate
2-hydroxy-5-[(2R,3R,4S,5R)-3,4,5-trihydroxyoxan-2-yl]oxybenzoic acid
2-[(2-Nitrophenyl)methylthio]-1,3-benzoxazole
C14H10N2O3S (286.04121100000003)
(2-Methylbenzimidazol-1-yl)-[(5-nitro-2-thienyl)methylene]amine
C13H10N4O2S (286.05244400000004)
N-[(2-nitrophenyl)-oxomethyl]-2-pyridinecarbohydrazide
2-Furancarboxylic acid (2-acetyl-1-benzothiophen-3-yl) ester
4-Methoxy-1,3-dimethyl-6-thiophen-2-yl-8-cyclohepta[c]furanone
2-cyano-3-oxo-N-[4-(trifluoromethoxy)phenyl]butanamide
C12H9F3N2O3 (286.05652399999997)
3-(4-Chlorophenyl)-3-oxo-2-(2-phenylhydrazono)propanal
1-(5-Fluoro-3-methyl-1-benzofuran-2-yl)-3-(2-thienyl)-2-propen-1-one
4-oxo-2-(trifluoromethyl)-1H-quinazoline-6-carboxylic acid ethyl ester
C12H9F3N2O3 (286.05652399999997)
N-(2-hydroxybenzylidene)-2-(phenylthio)acetohydrazide
hydrogen ({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)phosphonate
3,4,5-Trihydroxy-6-(2-hydroxyphenoxy)oxane-2-carboxylic acid
3,5-dihydroxy-2-[(2E)-3-(4-hydroxyphenyl)prop-2-enoyl]cyclohexa-2,5-diene-1,4-dione
[(E)-5-(4-methoxyphenyl)-3-oxopent-4-enyl] hydrogen sulate
C12H14O6S (286.05110640000004)
4-Acetoxymethyl-6-chloromethyl-2,5-dimethoxy-2,4,6-cycloheptatrien-1-one
cytosylglucuronate
A carbohydrate acid derivative anion that is the conjugate base of cytosylglucuronic acid, obtained by deprotonation of the carboxy group.
2,3-dihydroxybenzoic acid 3-O-beta-D-xyloside
A monohydroxybenzoic acid that is 2-hydroxybenzoic acid in which the hydrogen at position 3 is replaced by a beta-D-xylosyloxy group.
tenofovir(1-)
A phosphorus oxoanion resulting from the removal of one proton from the phosphonic acid group of tenofovir. The major microspecies at pH 7.3.
catechol beta-D-glucuronide
A glucosiduronic acid that is beta-D-glucuronic acid in which the anomeric hydroxyl hydrogen has been replaced by a 2-hydroxyphenyl group.
2-(3,4-dihydroxyphenyl)-6,7-dihydroxychromen-4-one
1,2,5,7-tetrahydroxy-4-methylanthracene-9,10-dione
2-(3,4-dihydroxyphenyl)-7-hydroxy-1-benzofuran-4-carboxylic acid
(10r)-7,14-dihydroxy-10-methoxy-2,9-dioxatetracyclo[6.6.2.0⁴,¹⁶.0¹¹,¹⁵]hexadeca-1(15),4(16),5,7,11,13-hexaen-3-one
1,2,8-trihydroxy-3-(hydroxymethyl)anthracene-9,10-dione
2-(3,4-dihydroxyphenyl)-6,8-dihydroxychromen-4-one
1,2,3,7-tetrahydroxyxanthone; 2,3-methylene,1-me ether
{"Ingredient_id": "HBIN000608","Ingredient_name": "1,2,3,7-tetrahydroxyxanthone; 2,3-methylene,1-me ether","Alias": "NA","Ingredient_formula": "C15H10O6","Ingredient_Smile": "NA","Ingredient_weight": "0","OB_score": "NA","CAS_id": "200509-34-8","SymMap_id": "NA","TCMID_id": "NA","TCMSP_id": "NA","TCM_ID_id": "9615","PubChem_id": "NA","DrugBank_id": "NA"}
6-hydroxy-1-methoxy-2,3-methylenedioxy-xanthone
{"Ingredient_id": "HBIN012383","Ingredient_name": "6-hydroxy-1-methoxy-2,3-methylenedioxy-xanthone","Alias": "NA","Ingredient_formula": "C15H10O6","Ingredient_Smile": "Not Available","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "10421","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
7-hydroxy-1-methoxy-2,3-methylenedioxy xanthone
{"Ingredient_id": "HBIN013201","Ingredient_name": "7-hydroxy-1-methoxy-2,3-methylenedioxy xanthone","Alias": "NA","Ingredient_formula": "C15H10O6","Ingredient_Smile": "COC1=C2C(=CC3=C1OCO3)OC4=C(C2=O)C=C(C=C4)O","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "31223","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
8-hydroxy-11-methoxy-[1,3]dioxolo[4,5-b]xanthen-10-one
{"Ingredient_id": "HBIN013754","Ingredient_name": "8-hydroxy-11-methoxy-[1,3]dioxolo[4,5-b]xanthen-10-one","Alias": "NA","Ingredient_formula": "C15H10O6","Ingredient_Smile": "COC1=C2C(=CC3=C1OCO3)OC4=C(C2=O)C=C(C=C4)O","Ingredient_weight": "NA","OB_score": "NA","CAS_id": "NA","SymMap_id": "NA","TCMID_id": "10422","TCMSP_id": "NA","TCM_ID_id": "NA","PubChem_id": "NA","DrugBank_id": "NA"}
methyl 2-[4,5-dimethoxy-2-(methylsulfanyl)-3,6-dioxocyclohexa-1,4-dien-1-yl]acetate
C12H14O6S (286.05110640000004)
1,3,5-trihydroxy-7-(hydroxymethyl)anthracene-9,10-dione
4-hydroxy-3-{[(2s,3r,4s,5s)-3,4,5-trihydroxyoxan-2-yl]oxy}benzoic acid
2-amino-n-[(3r,4s,5r)-3,4-dihydroxy-5-[(phosphonooxy)methyl]oxolan-2-yl]ethanimidic acid
2-hydroxy-3-{[(2s,3r,4s,5r)-3,4,5-trihydroxyoxan-2-yl]oxy}benzoic acid
{8-hydroxy-4,9-dioxonaphtho[2,3-c]furan-1-yl}methyl acetate
7-bromo-6-hydroxy-8-methoxy-3-methyl-3,4-dihydro-2-benzopyran-1-one
4,9-dihydroxy-6-methoxy-7-methylphenalene-1,2,3-trione
2-(2,3-dihydroxyphenyl)-5,7-dihydroxychromen-4-one
3-(3,4-dihydroxyphenyl)-5,7-dihydroxychromen-2-one
2-(2,5-dihydroxyphenyl)-5,7-dihydroxychromen-4-one
1,2,3,5-tetrahydroxy-6-methylanthracene-9,10-dione
4-hydroxy-3-[(3,4,5-trihydroxyoxan-2-yl)oxy]benzoic acid
3,7,13-trihydroxy-15-methyl-4,10-dioxatetracyclo[7.7.0.0²,⁶.0¹¹,¹⁶]hexadeca-1(9),2(6),7,11(16),12,14-hexaen-5-one
1,4,5,7-tetrahydroxy-2-methylanthracene-9,10-dione
3-(3,5-dihydroxyphenyl)-5,7-dihydroxychromen-4-one
(2r,3s)-2,3-dihydroxy-2-[(4-hydroxy-3-methoxyphenyl)methyl]butanedioic acid
(3r)-5-bromo-6-hydroxy-8-methoxy-3-methyl-3,4-dihydro-2-benzopyran-1-one
(3r)-7-bromo-6-hydroxy-8-methoxy-3-methyl-3,4-dihydro-2-benzopyran-1-one
(2s)-2-methoxy-6-[5-(prop-1-yn-1-yl)thiophen-2-yl]hexa-3,5-diyn-1-yl acetate
3-(2,4-dihydroxyphenyl)-7,8-dihydroxychromen-4-one
(2s)-2-(3,4,5-trihydroxybenzoyloxy)butanedioic acid
13-formyl-5,11-dihydroxy-3-methyl-8-oxatricyclo[7.4.0.0²,⁷]trideca-1(9),2(7),3,5,10,12-hexaene-4-carboxylic acid
(2s,3r,4s,5r)-3,4,5-trihydroxyoxan-2-yl 2,5-dihydroxybenzoate
2-(3,4-dihydroxyphenyl)-7,8-dihydroxychromen-4-one
5-bromo-6-hydroxy-8-methoxy-3-methyl-3,4-dihydro-2-benzopyran-1-one
2-hydroxy-5-{[(2r,3r,4s,5r)-3,4,5-trihydroxyoxan-2-yl]oxy}benzoic acid
1,4,5,8-tetrahydroxy-2-methylanthracene-9,10-dione
7,14-dihydroxy-10-methoxy-2,9-dioxatetracyclo[6.6.2.0⁴,¹⁶.0¹¹,¹⁵]hexadeca-1(15),4(16),5,7,11,13-hexaen-3-one
2-methoxy-6-[5-(prop-1-yn-1-yl)thiophen-2-yl]hexa-3,5-diyn-1-yl acetate
n'-[2-(3-bromo-4-hydroxyphenyl)ethyl]ethanediamide
C10H11BrN2O3 (285.99529959999995)
