2'-Hydroxygenistein (BioDeep_00000004134)

Secondary id: BioDeep_00000270323, BioDeep_00000396351

human metabolite PANOMIX_OTCML-2023

代谢物信息卡片

3-(2,4-Dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one, 9CI

化学式: C15H10O6 (286.047736)
中文名称: 2-羟基金雀异黄素
谱图信息: 最多检出来源 Viridiplantae(plant) 0.4%

Reviewed

Last reviewed on 2024-08-06.

Cite this Page

2'-Hydroxygenistein. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/2_-hydroxygenistein (retrieved 2024-09-19) (BioDeep RN: BioDeep_00000004134). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: c1(cc(c2c(c1)occ(c2=O)c1c(cc(cc1)O)O)O)O
InChI: InChI=1S/C15H10O6/c16-7-1-2-9(11(18)3-7)10-6-21-13-5-8(17)4-12(19)14(13)15(10)20/h1-6,16-19H

描述信息

Isolated from Cajanus cajan (pigeon pea), Dolichos biflorus (papadi), Lablab niger (hyacinth bean), Phaseolus vulgaris (kidney bean) and Phaseolus coccineus (scarlet runner bean). 2-Hydroxygenistein is found in many foods, some of which are pulses, walnut, saskatoon berry, and garden tomato (variety).
2-Hydroxygenistein is found in adzuki bean. 2-Hydroxygenistein is isolated from Cajanus cajan (pigeon pea), Dolichos biflorus (papadi), Lablab niger (hyacinth bean), Phaseolus vulgaris (kidney bean) and Phaseolus coccineus (scarlet runner bean).

同义名列表

7 个代谢物同义名

3-(2,4-Dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one, 9CI; 3-(2,4-Dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one; 3-(2,4-dihydroxyphenyl)-5,7-dihydroxychromen-4-one; 5,7,2,4-Tetrahydroxy-isoflavone; 2,4,5,7-Tetrahydroxy-Isoflavone; 2,4,5,7-Tetrahydroxyisoflavone; 2-Hydroxygenistein

数据库引用编号

15 个数据库交叉引用编号

ChEBI: CHEBI:70031
KEGG: C12134
PubChem: 5282074
HMDB: HMDB0034014
Metlin: METLIN47834
ChEMBL: CHEMBL6665
LipidMAPS: LMPK12050327
MetaCyc: CPD-6641
KNApSAcK: C00009453
foodb: FDB012251
chemspider: 4445299
CAS: 1156-78-1
PMhub: MS000015873
3DMET: B04428
NIKKAJI: J397.872I

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

55 个相关的物种来源信息

256638 Euchresta formosana:
648866 Grona styracifolia: 10.1016/J.PHYTOCHEM.2007.02.015
200492 Sophora alopecuroides: 10.1016/0031-9422(94)00720-E
3884 Phaseolus lunatus: 10.1016/S0031-9422(00)81280-7
463862 Ficus nervosa: 10.1002/CBDV.200900227
3870 Lupinus albus:
28959 Lupinus texensis: 10.1080/14786419.2010.523423
3885 Phaseolus vulgaris:
3871 Lupinus angustifolius: 10.1007/BF01020159
3886 Phaseolus coccineus: 10.1016/S0031-9422(00)80697-4
1899109 Erythrina sacleuxii: 10.1016/S0031-9422(00)00349-6
3914 Vigna angularis: 10.1271/BBB1961.51.349
51156 Cadophora gregata: 10.1271/BBB1961.51.349
2595086 Flemingia paniculata: 10.1021/NP0206108
3873 Lupinus luteus:
3830 Crotalaria pallida: 10.1016/J.BMCL.2003.11.074
56060 Butea monosperma: 10.1016/J.BMCL.2008.12.064
3915 Vigna mungo: 10.1515/ZNC-1984-9-1006
1237651 Crotalaria lachnophora: 10.1021/NP1005218
520843 Flemingia macrophylla: 10.1016/S0031-9422(00)83979-5
3874 Lupinus polyphyllus: 10.1248/CPB.41.394
53233 Lupinus nanus: 10.1515/ZNC-1983-3-407
53215 Lupinus arcticus: 10.1515/ZNC-1983-3-407
53226 Lupinus elegans: 10.1515/ZNC-1983-3-407
185702 Apios americana: 10.1016/0031-9422(82)80152-0
157791 Vigna radiata: 10.1515/ZNC-1983-9-1004
53240 Lupinus pubescens: 10.21608/BFSA.2000.66325
256638 Euchresta formosana:
648866 Grona styracifolia: 10.1016/J.PHYTOCHEM.2007.02.015
200492 Sophora alopecuroides: 10.1016/0031-9422(94)00720-E
3884 Phaseolus lunatus: 10.1016/S0031-9422(00)81280-7
463862 Ficus nervosa: 10.1002/CBDV.200900227
3870 Lupinus albus:
28959 Lupinus texensis: 10.1080/14786419.2010.523423
3885 Phaseolus vulgaris:
3871 Lupinus angustifolius: 10.1007/BF01020159
3886 Phaseolus coccineus: 10.1016/S0031-9422(00)80697-4
1899109 Erythrina sacleuxii: 10.1016/S0031-9422(00)00349-6
3914 Vigna angularis: 10.1271/BBB1961.51.349
51156 Cadophora gregata: 10.1271/BBB1961.51.349
2595086 Flemingia paniculata: 10.1021/NP0206108
3873 Lupinus luteus:
3830 Crotalaria pallida: 10.1016/J.BMCL.2003.11.074
56060 Butea monosperma: 10.1016/J.BMCL.2008.12.064
3915 Vigna mungo: 10.1515/ZNC-1984-9-1006
1237651 Crotalaria lachnophora: 10.1021/NP1005218
520843 Flemingia macrophylla: 10.1016/S0031-9422(00)83979-5
3874 Lupinus polyphyllus: 10.1248/CPB.41.394
53233 Lupinus nanus: 10.1515/ZNC-1983-3-407
53215 Lupinus arcticus: 10.1515/ZNC-1983-3-407
53226 Lupinus elegans: 10.1515/ZNC-1983-3-407
185702 Apios americana: 10.1016/0031-9422(82)80152-0
157791 Vigna radiata: 10.1515/ZNC-1983-9-1004
53240 Lupinus pubescens: 10.21608/BFSA.2000.66325
9606 Homo sapiens: -

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Young Hye Seo, Ju-Hyun Jeon, Miran Jeong, Seung Mok Ryu, Won Kyung Jeon, Dae Sik Jang, Sang Hee Shim, Dongho Lee, Jung-Hye Choi, Jun Lee. Chemical Constituents of Apios americana Tubers and Their Inhibitory Activities on Nitric Oxide Production in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages. Journal of natural products. 2018 07; 81(7):1598-1603. doi: 10.1021/acs.jnatprod.8b00182. [PMID: 29932657]
Guoan Shen, David Huhman, Zhentian Lei, John Snyder, Lloyd W Sumner, Richard A Dixon. Characterization of an isoflavonoid-specific prenyltransferase from Lupinus albus. Plant physiology. 2012 May; 159(1):70-80. doi: 10.1104/pp.112.195271. [PMID: 22430842]
Maurice Ducret Awouafack, Peter Spiteller, Marc Lamshöft, Souvik Kusari, Bojidarka Ivanova, Pierre Tane, Michael Spiteller. Antimicrobial isopropenyl-dihydrofuranoisoflavones from Crotalaria lachnophora. Journal of natural products. 2011 Feb; 74(2):272-8. doi: 10.1021/np1005218. [PMID: 21265557]
Sylwia Pawlak-Sprada, Maciej Stobiecki, Joanna Deckert. Activation of phenylpropanoid pathway in legume plants exposed to heavy metals. Part II. Profiling of isoflavonoids and their glycoconjugates induced in roots of lupine (Lupinus luteus) seedlings treated with cadmium and lead. Acta biochimica Polonica. 2011; 58(2):217-23. doi: . [PMID: 21503277]
Maciej Stobiecki, Anna Staszków, Anna Piasecka, Pedro M Garcia-Lopez, Francisco Zamora-Natera, Piotr Kachlicki. LC-MSMS profiling of flavonoid conjugates in wild Mexican lupine, Lupinus reflexus. Journal of natural products. 2010 Jul; 73(7):1254-60. doi: 10.1021/np100139d. [PMID: 20568784]
Li-Wen Chen, Ming-Jen Cheng, Chien-Fang Peng, Ih-Sheng Chen. Secondary metabolites and antimycobacterial activities from the roots of Ficus nervosa. Chemistry & biodiversity. 2010 Jul; 7(7):1814-21. doi: 10.1002/cbdv.200900227. [PMID: 20658670]
Swati Madan, Gyanendra Nath Singh, Kanchan Kohli, Mohammed Ali, Yatendra Kumar, Raman Mohan Singh, Om Prakash. Isoflavonoids from Flemingia strobilifera (L) R. Br. roots. Acta poloniae pharmaceutica. 2009 May; 66(3):297-303. doi: ". [PMID: 19645330]
Li Tian, Gregory J Peel, Zhentian Lei, Naveed Aziz, Xinbin Dai, Ji He, Bonnie Watson, Patrick X Zhao, Lloyd W Sumner, Richard A Dixon. Transcript and proteomic analysis of developing white lupin (Lupinus albus L.) roots. BMC plant biology. 2009 Jan; 9(?):1. doi: 10.1186/1471-2229-9-1. [PMID: 19123941]
Ting Yin, Hua Liu, Bin Wang, Guang-Zhong Tu, Hong Liang, Yu-Ying Zhao. [Chemical constituents from Spatholobus sinensis]. Yao xue xue bao = Acta pharmaceutica Sinica. 2008 Jan; 43(1):67-70. doi: . [PMID: 18357735]
Cheryl Lans. Comparison of plants used for skin and stomach problems in Trinidad and Tobago with Asian ethnomedicine. Journal of ethnobiology and ethnomedicine. 2007 Jan; 3(?):3. doi: 10.1186/1746-4269-3-3. [PMID: 17207273]
P M García-López, P Kachlicki, F Zamora-Natera, J Ruiz-Moreno, M Stobiecki. Profiling isoflavone conjugates in different organs of Lupinus exaltatus Zucc. Phytochemical analysis : PCA. 2006 May; 17(3):184-91. doi: 10.1002/pca.904. [PMID: 16749426]
Piotr Kachlicki, Lukasz Marczak, Lucien Kerhoas, Jacques Einhorn, Maciej Stobiecki. Profiling isoflavone conjugates in root extracts of lupine species with LC/ESI/MSn systems. Journal of mass spectrometry : JMS. 2005 Aug; 40(8):1088-103. doi: 10.1002/jms.884. [PMID: 15971291]
Hun Sung Yoo, Ji Suk Lee, Chul Young Kim, Jinwoong Kim. Flavonoids of Crotalaria sessiliflora. Archives of pharmacal research. 2004 May; 27(5):544-6. doi: 10.1007/bf02980129. [PMID: 15202561]
Horng-Huey Ko, Jing-Ru Weng, Lo-Ti Tsao, Ming-Hong Yen, Jih-Pyang Wang, Chun-Nan Lin. Anti-inflammatory flavonoids and pterocarpanoid from Crotalaria pallida and C. assamica. Bioorganic & medicinal chemistry letters. 2004 Feb; 14(4):1011-4. doi: 10.1016/j.bmcl.2003.11.074. [PMID: 15013012]
George Duker-Eshun, Jerzy W Jaroszewski, William A Asomaning, Francis Oppong-Boachie, S Brøgger Christensen. Antiplasmodial constituents of Cajanus cajan. Phytotherapy research : PTR. 2004 Feb; 18(2):128-30. doi: 10.1002/ptr.1375. [PMID: 15022164]
P Bednarek, L Kerhoas, J Einhorn, R Frański, P Wojtaszek, M Rybus-Zajac, M Stobiecki. Profiling of flavonoid conjugates in Lupinus albus and Lupinus angustifolius responding to biotic and abiotic stimuli. Journal of chemical ecology. 2003 May; 29(5):1127-42. doi: 10.1023/a:1023877422403. [PMID: 12857026]