Norartocarpetin (BioDeep_00000270593)

Main id: BioDeep_00000017498

 

PANOMIX_OTCML-2023 Antitumor activity natural product


代谢物信息卡片


2- (2,4-Dihydroxyphenyl) -5,7-dihydroxy-4H-1-benzopyran-4-one

化学式: C15H10O6 (286.047736)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: O=C1C=C(C2=CC=C(O)C=C2O)OC3=CC(O)=CC(O)=C13
InChI:

描述信息

Norartocarpetin is a tyrosinase inhibitor. Norartocarpetin has strong tyrosinase inhibitory activity with an IC50 value of 0.47 μM. Norartocarpetin as an antibrowning agent can be used for the research of food systems. Norartocarpetin also has a significant anticancer activity in lung carcinoma cells (NCI-H460) with an IC50 value of 22 μM. Norartocarpetin has antiproliferative effects are mediated via targeting Ras/Raf/MAPK signalling pathway, mitochondrial mediated apoptosis, S-phase cell cycle arrest and suppression of cell migration and invasion in human lung carcinoma cells[1][2].
Norartocarpetin is a tyrosinase inhibitor. Norartocarpetin has strong tyrosinase inhibitory activity with an IC50 value of 0.47 μM. Norartocarpetin as an antibrowning agent can be used for the research of food systems. Norartocarpetin also has a significant anticancer activity in lung carcinoma cells (NCI-H460) with an IC50 value of 22 μM. Norartocarpetin has antiproliferative effects are mediated via targeting Ras/Raf/MAPK signalling pathway, mitochondrial mediated apoptosis, S-phase cell cycle arrest and suppression of cell migration and invasion in human lung carcinoma cells[1][2].

同义名列表

2 个代谢物同义名

Norartocarpetin; 2- (2,4-Dihydroxyphenyl) -5,7-dihydroxy-4H-1-benzopyran-4-one



数据库引用编号

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59 个相关的物种来源信息

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