Datiscetin (BioDeep_00000007764)

   

PANOMIX_OTCML-2023


代谢物信息卡片


3,5,7-Trihydroxy-2- (2-hydroxyphenyl) -4H-1-benzopyran-4-one

化学式: C15H10O6 (286.0477)
中文名称: 橡精
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1(O)=CC2OC(C3C(O)=CC=CC=3)=C(O)C(=O)C=2C(O)=C1
InChI: InChI=1S/C15H10O6/c16-7-5-10(18)12-11(6-7)21-15(14(20)13(12)19)8-3-1-2-4-9(8)17/h1-6,16-18,20H

描述信息

同义名列表

3 个代谢物同义名

Datiscetin; 3,5,7-Trihydroxy-2- (2-hydroxyphenyl) -4H-1-benzopyran-4-one; Datiscetin



数据库引用编号

15 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 11 ABCB1, CASP8, CYP3A4, FADD, JAK2, NCOA3, NOS2, NR1I3, STAT1, STAT2, VDR
Peripheral membrane protein 1 JAK2
Endoplasmic reticulum membrane 3 CYP3A4, CYP3A5, SPP1
Nucleus 11 CASP8, FOS, JAK2, JUND, NCOA3, NOS2, NR1I2, NR1I3, STAT1, STAT2, VDR
cytosol 10 CASP8, FADD, FOS, JAK2, NCOA3, NOS2, NR1I3, STAT1, STAT2, VDR
dendrite 1 STAT1
nuclear body 1 NR1I2
nucleoplasm 11 CASP8, FOS, JAK2, JUND, NCOA3, NOS2, NR1I2, NR1I3, STAT1, STAT2, VDR
RNA polymerase II transcription regulator complex 5 FOS, JUND, STAT1, STAT2, VDR
Cell membrane 2 ABCB1, SPP1
lamellipodium 1 CASP8
Multi-pass membrane protein 3 ABCB1, CATSPER3, SPP1
cell surface 1 ABCB1
glutamatergic synapse 1 JAK2
Golgi apparatus 1 SPP1
mitochondrial inner membrane 1 CYP24A1
postsynapse 1 JAK2
Cytoplasm, cytosol 1 NOS2
acrosomal vesicle 1 CATSPER3
plasma membrane 7 ABCB1, CATSPER3, FADD, JAK2, NOS2, SPP1, STAT2
Membrane 4 ABCB1, CYP3A4, CYP3A5, JAK2
apical plasma membrane 1 ABCB1
axon 1 STAT1
caveola 1 JAK2
extracellular exosome 3 ABCB1, NCOA3, SPP1
endoplasmic reticulum 2 CATSPER3, FOS
extracellular space 1 SPP1
perinuclear region of cytoplasm 3 NOS2, SPP1, STAT1
mitochondrion 2 CASP8, CYP24A1
protein-containing complex 3 CASP8, NCOA3, STAT1
intracellular membrane-bounded organelle 2 CYP3A4, CYP3A5
Microsome membrane 2 CYP3A4, CYP3A5
Secreted 1 SPP1
extracellular region 1 SPP1
cytoplasmic side of plasma membrane 2 FADD, JAK2
mitochondrial outer membrane 1 CASP8
transcription regulator complex 2 JUND, NR1I2
motile cilium 1 CATSPER3
nucleolus 1 STAT1
Cytoplasm, P-body 1 NOS2
P-body 1 NOS2
Apical cell membrane 1 ABCB1
Cell projection, lamellipodium 1 CASP8
Cytoplasm, perinuclear region 1 NOS2
Membrane raft 1 JAK2
Cytoplasm, cytoskeleton 1 NR1I3
focal adhesion 1 JAK2
Peroxisome 1 NOS2
peroxisomal matrix 1 NOS2
receptor complex 1 VDR
chromatin 8 FOS, JUND, NCOA3, NR1I2, NR1I3, STAT1, STAT2, VDR
cell projection 1 SPP1
cytoskeleton 3 CASP8, JAK2, NR1I3
Endomembrane system 1 JAK2
endosome lumen 1 JAK2
Cell projection, cilium, flagellum membrane 1 CATSPER3
euchromatin 1 JAK2
cell body 2 CASP8, FADD
intermediate filament cytoskeleton 1 NR1I2
endoplasmic reticulum lumen 1 SPP1
nuclear matrix 1 FOS
transcription repressor complex 1 JUND
extrinsic component of cytoplasmic side of plasma membrane 1 JAK2
protein-DNA complex 1 FOS
external side of apical plasma membrane 1 ABCB1
CD95 death-inducing signaling complex 2 CASP8, FADD
death-inducing signaling complex 2 CASP8, FADD
ripoptosome 2 CASP8, FADD
extrinsic component of plasma membrane 1 JAK2
granulocyte macrophage colony-stimulating factor receptor complex 1 JAK2
interleukin-12 receptor complex 1 JAK2
interleukin-23 receptor complex 1 JAK2
transcription factor AP-1 complex 2 FOS, JUND
cortical cytoskeleton 1 NOS2
ISGF3 complex 2 STAT1, STAT2
CatSper complex 1 CATSPER3


文献列表

  • Yelin Kang, Bong-Gyu Kim, Sunghoon Kim, Youngshim Lee, Youngdae Yoon. Inhibitory potential of flavonoids on PtdIns(3,4,5)P3 binding with the phosphoinositide-dependent kinase 1 pleckstrin homology domain. Bioorganic & medicinal chemistry letters. 2017 02; 27(3):420-426. doi: 10.1016/j.bmcl.2016.12.051. [PMID: 28049590]
  • Yearam Jung, Soon Young Shin, Yeonjoong Yong, Hyeryoung Jung, Seunghyun Ahn, Young Han Lee, Yoongho Lim. Plant-derived flavones as inhibitors of aurora B kinase and their quantitative structure-activity relationships. Chemical biology & drug design. 2015 May; 85(5):574-85. doi: 10.1111/cbdd.12445. [PMID: 25298094]
  • Maria Schubert, Anna N Melnikova, Nikola Mesecke, Elena K Zubkova, Rocco Fortte, Denis R Batashev, Inga Barth, Norbert Sauer, Yuri V Gamalei, Natalia S Mamushina, Lutz F Tietze, Olga V Voitsekhovskaja, Katharina Pawlowski. Two novel disaccharides, rutinose and methylrutinose, are involved in carbon metabolism in Datisca glomerata. Planta. 2010 Feb; 231(3):507-21. doi: 10.1007/s00425-009-1049-5. [PMID: 19915863]
  • H X Xu, S F Lee. Activity of plant flavonoids against antibiotic-resistant bacteria. Phytotherapy research : PTR. 2001 Feb; 15(1):39-43. doi: 10.1002/1099-1573(200102)15:1<39::aid-ptr684>3.0.co;2-r. [PMID: 11180521]
  • M Abou-Shoer, G E Ma, X H Li, N M Koonchanok, R L Geahlen, C J Chang. Flavonoids from Koelreuteria henryi and other sources as protein-tyrosine kinase inhibitors. Journal of natural products. 1993 Jun; 56(6):967-9. doi: 10.1021/np50096a027. [PMID: 8350096]