Murideoxycholate (BioDeep_00001871995)
Main id: BioDeep_00000018632
Bile acids
代谢物信息卡片
3alpha,6beta-Dihydroxy-5beta-cholan-24-oic Acid
化学式: C24H40O4 (392.2926)
中文名称: 鼠胆酸脱氧胆酸
谱图信息:
最多检出来源 Mus musculus(not specific) 7.97%
Reviewed
Last reviewed on 2024-07-16.
Cite this Page
Murideoxycholate. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China.
https://query.biodeep.cn/s/murideoxycholate (retrieved
2024-12-22) (BioDeep RN: BioDeep_00001871995). Licensed
under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).
分子结构信息
SMILES: C1[C@]2(C)[C@@]3([H])CC[C@]4(C)[C@@]([H])([C@]([H])(C)CCC(O)=O)CC[C@@]4([H])[C@]3([H])C[C@@H](O)[C@]2([H])C[C@H](O)C1
InChI: InChI=1S/C24H40O4/c1-14(4-7-22(27)28)17-5-6-18-16-13-21(26)20-12-15(25)8-10-24(20,3)19(16)9-11-23(17,18)2/h14-21,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15-,16+,17-,18+,19+,20+,21-,23-,24-/m1/s1
描述信息
A 3alpha-hydroxy steroid that is cholan-24-oic acid substituted by hydroxy groups at positions 3 and 6.
D005765 - Gastrointestinal Agents > D001647 - Bile Acids and Salts
D005765 - Gastrointestinal Agents > D002793 - Cholic Acids
同义名列表
数据库引用编号
10 个数据库交叉引用编号
- ChEBI: CHEBI:52030
- KEGG: C15515
- PubChem: 5283821
- ChEMBL: CHEMBL272620
- LipidMAPS: LMST04010025
- CAS: 668-49-5
- MetaboLights: MTBLC52030
- PubChem: 17396507
- NIKKAJI: J472.757F
- RefMet: Murideoxycholic acid
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Jing Zhong, Xiaofang He, Xinxin Gao, Qiaohong Liu, Yu Zhao, Ying Hong, Weize Zhu, Juan Yan, Yifan Li, Yan Li, Ningning Zheng, Yiyang Bao, Hao Wang, Junli Ma, Wenjin Huang, Zekun Liu, Yuanzhi Lyu, Xisong Ke, Wei Jia, Cen Xie, Yiyang Hu, Lili Sheng, Houkai Li. Hyodeoxycholic acid ameliorates nonalcoholic fatty liver disease by inhibiting RAN-mediated PPARα nucleus-cytoplasm shuttling.
Nature communications.
2023 09; 14(1):5451. doi:
10.1038/s41467-023-41061-8. [PMID: 37673856] - Junliang Kuang, Jieyi Wang, Yitao Li, Mengci Li, Mingliang Zhao, Kun Ge, Dan Zheng, Kenneth C P Cheung, Boya Liao, Shouli Wang, Tianlu Chen, Yinan Zhang, Congrong Wang, Guang Ji, Peng Chen, Hongwei Zhou, Cen Xie, Aihua Zhao, Weiping Jia, Xiaojiao Zheng, Wei Jia. Hyodeoxycholic acid alleviates non-alcoholic fatty liver disease through modulating the gut-liver axis.
Cell metabolism.
2023 Aug; ?(?):. doi:
10.1016/j.cmet.2023.07.011. [PMID: 37591244] - Minghao Hu, Tingting Gou, Yuchen Chen, Min Xu, Rong Chen, Tao Zhou, Junjing Liu, Cheng Peng, Qiang Ye. A Novel Drug Delivery System: Hyodeoxycholic Acid-Modified Metformin Liposomes for Type 2 Diabetes Treatment.
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2023 Mar; 28(6):. doi:
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2022 07; 36(7):849-859. doi:
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