3,4-dihydro-2H-pyrrole-2-carboxylic acid (BioDeep_00001868843)

Main id: BioDeep_00000015332

 

PANOMIX_OTCML-2023 natural product


代谢物信息卡片


3,4-dihydro-2H-pyrrole-2-carboxylic acid

化学式: C5H7NO2 (113.0477)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1CC(N=C1)C(=O)O
InChI: InChI=1S/C5H7NO2/c7-5(8)4-2-1-3-6-4/h3-4H,1-2H2,(H,7,8)

描述信息

同义名列表

2 个代谢物同义名

3,4-dihydro-2H-pyrrole-2-carboxylic acid; Delta1-Pyrroline-5-carboxylate



数据库引用编号

10 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

20 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 6 ARG1, CYP1A1, DAO, DLK1, GPX1, OAT
Peripheral membrane protein 3 CYP1A1, DAO, HSD17B6
Endoplasmic reticulum membrane 1 CYP1A1
Nucleus 3 ALDH7A1, ARG1, GPX4
cytosol 7 ALDH4A1, ALDH7A1, ARG1, DAO, GLS, GPX1, GPX4
nucleoplasm 2 OAT, PRODH
Cell membrane 2 DAO, PRND
Cytoplasmic granule 1 ARG1
Early endosome membrane 1 HSD17B6
Synapse 1 GLS
cell surface 1 TNR
glutamatergic synapse 1 TNR
Golgi apparatus 2 FUT2, PROC
Golgi membrane 1 FUT2
mitochondrial inner membrane 4 ALDH18A1, CYP1A1, OTC, PRODH
Cytoplasm, cytosol 2 DAO, GLS
plasma membrane 3 DAO, PRND, PTN
presynaptic active zone 1 DAO
Membrane 1 DLK1
extracellular exosome 4 ALDH7A1, DAO, FUT2, GPX4
Lumenal side 1 HSD17B6
endoplasmic reticulum 3 HSD17B6, PROC, PTN
extracellular space 6 ARG1, DAO, DLK1, PROC, PTN, TNR
Schaffer collateral - CA1 synapse 2 PTN, TNR
bicellular tight junction 1 DAO
mitochondrion 11 ALDH18A1, ALDH4A1, ALDH7A1, CYP1A1, GLS, GPX1, GPX4, OAT, OTC, PRODH, PYCR1
protein-containing complex 2 GPX4, PTN
intracellular membrane-bounded organelle 3 CYP1A1, HSD17B6, PRODH
Microsome membrane 2 CYP1A1, HSD17B6
Secreted 3 DAO, PROC, PTN
extracellular region 6 ARG1, DAO, PRND, PROC, PTN, TNR
Single-pass membrane protein 1 DLK1
Mitochondrion matrix 2 OAT, OTC
mitochondrial matrix 8 ALDH4A1, ALDH7A1, GLS, GPX1, OAT, OTC, PRODH, PYCR1
Extracellular side 1 DAO
external side of plasma membrane 1 PRND
Secreted, extracellular space, extracellular matrix 1 TNR
Single-pass type II membrane protein 1 FUT2
Mitochondrion inner membrane 2 ALDH18A1, CYP1A1
Membrane raft 1 TNR
Peroxisome 1 DAO
Peroxisome matrix 1 DAO
peroxisomal matrix 1 DAO
collagen-containing extracellular matrix 1 TNR
cell projection 1 DAO
Secreted, extracellular space 1 DAO
[Isoform 1]: Mitochondrion 2 ALDH7A1, GLS
Lipid-anchor, GPI-anchor 1 PRND
nuclear envelope 1 GPX4
Golgi cisterna membrane 1 FUT2
[Isoform 2]: Cytoplasm, cytosol 1 ALDH7A1
side of membrane 1 PRND
Golgi lumen 1 PROC
endoplasmic reticulum lumen 1 PROC
specific granule lumen 2 ARG1, DAO
azurophil granule lumen 1 ARG1
Golgi apparatus, Golgi stack membrane 1 FUT2
perineuronal net 1 TNR
[Isoform 3]: Mitochondrion 1 GLS
[Glutaminase kidney isoform, mitochondrial 68 kDa chain]: Mitochondrion matrix 1 GLS
[Glutaminase kidney isoform, mitochondrial 65 kDa chain]: Mitochondrion matrix 1 GLS
[Isoform Mitochondrial]: Mitochondrion 1 GPX4
tenascin complex 1 TNR
[Isoform Cytoplasmic]: Cytoplasm 1 GPX4


文献列表

  • Giuseppe Forlani, Giuseppe Sabbioni, Simone Barera, Dietmar Funck. A complex array of factors regulate the activity of Arabidopsis thaliana δ1 -pyrroline-5-carboxylate synthetase isoenzymes to ensure their specific role in plant cell metabolism. Plant, cell & environment. 2024 Apr; 47(4):1348-1362. doi: 10.1111/pce.14817. [PMID: 38223941]
  • Yao Zheng, Cécile Cabassa-Hourton, Holger Eubel, Guillaume Chevreux, Laurent Lignieres, Emilie Crilat, Hans-Peter Braun, Sandrine Lebreton, Arnould Savouré. Pyrroline-5-carboxylate metabolism protein complex detected in Arabidopsis thaliana leaf mitochondria. Journal of experimental botany. 2023 Oct; ?(?):. doi: 10.1093/jxb/erad406. [PMID: 37843921]
  • Yao Zheng, Cécile Cabassa-Hourton, Séverine Planchais, Emilie Crilat, Gilles Clément, Matthieu Dacher, Nina Durand, Marianne Bordenave-Jacquemin, Anne Guivarc'h, Corentin Dourmap, Pierre Carol, Sandrine Lebreton, Arnould Savouré. Pyrroline-5-carboxylate dehydrogenase is an essential enzyme for proline dehydrogenase function during dark-induced senescence in Arabidopsis thaliana. Plant, cell & environment. 2023 03; 46(3):901-917. doi: 10.1111/pce.14529. [PMID: 36583533]
  • Chengcheng Chen, Xiaoyue Cui, Pingying Zhang, Zheng Wang, Jianxia Zhang. Expression of the pyrroline-5-carboxylate reductase (P5CR) gene from the wild grapevine Vitis yeshanensis promotes drought resistance in transgenic Arabidopsis. Plant physiology and biochemistry : PPB. 2021 Nov; 168(?):188-201. doi: 10.1016/j.plaphy.2021.10.004. [PMID: 34649022]
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  • Cong Guan, Yan-Hua Huang, Hui-Fang Cen, Xin Cui, Dan-Yang Tian, Yun-Wei Zhang. Overexpression of the Lolium perenne L. delta1-pyrroline 5-carboxylate synthase (LpP5CS) gene results in morphological alterations and salinity tolerance in switchgrass (Panicum virgatum L.). PloS one. 2019; 14(7):e0219669. doi: 10.1371/journal.pone.0219669. [PMID: 31310632]
  • Christian Blume, Julia Ost, Marco Mühlenbruch, Christoph Peterhänsel, Miriam Laxa. Low CO2 induces urea cycle intermediate accumulation in Arabidopsis thaliana. PloS one. 2019; 14(1):e0210342. doi: 10.1371/journal.pone.0210342. [PMID: 30650113]
  • Shumaila Muzammil, Asis Shrestha, Said Dadshani, Klaus Pillen, Shahid Siddique, Jens Léon, Ali Ahmad Naz. An Ancestral Allele of Pyrroline-5-carboxylate synthase1 Promotes Proline Accumulation and Drought Adaptation in Cultivated Barley. Plant physiology. 2018 10; 178(2):771-782. doi: 10.1104/pp.18.00169. [PMID: 30131422]
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  • Goon-Bo Kim, Young-Woo Nam. A novel Δ(1)-pyrroline-5-carboxylate synthetase gene of Medicago truncatula plays a predominant role in stress-induced proline accumulation during symbiotic nitrogen fixation. Journal of plant physiology. 2013 Feb; 170(3):291-302. doi: 10.1016/j.jplph.2012.10.004. [PMID: 23158502]
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  • Ziting Yao, Chengwu Zou, Hui Zhou, Jinzi Wang, Lidan Lu, Yang Li, Baoshan Chen. Δ(1)-pyrroline-5-carboxylate/glutamate biogenesis is required for fungal virulence and sporulation. PloS one. 2013; 8(9):e73483. doi: 10.1371/journal.pone.0073483. [PMID: 24039956]
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