GUANOSINE-5-triphosphATE (BioDeep_00001868319)

Main id: BioDeep_00000001617

 

BioNovoGene_Lab2019


代谢物信息卡片


guanosine 5-(tetrahydrogen triphosphate)

化学式: C10H16N5O14P3 (522.9906626)
中文名称: 鸟苷三磷酸, 5'-三磷酸鸟苷三钠三磷酸鸟苷三钠 钠盐 水合物
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=NC2=C(N1C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N=C(NC2=O)N
InChI: InChI=1S/C10H16N5O14P3/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1

描述信息

COVID info from PDB, Protein Data Bank, WikiPathways
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS

同义名列表

2 个代谢物同义名

guanosine 5-(tetrahydrogen triphosphate); GUANOSINE-5-triphosphATE



数据库引用编号

18 个数据库交叉引用编号

分类词条

4 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Sapna I, A Jayadeep. Enzyme-treated red rice (Oryza sativa L.) bran extracts mitigate inflammatory markers in RAW 264.7 macrophage cells and exhibit anti-inflammatory efficacy greater/comparable to ferulic acid, catechin, γ-tocopherol, and γ-oryzanol. Journal of ethnopharmacology. 2024 Apr; 323(?):117616. doi: 10.1016/j.jep.2023.117616. [PMID: 38142877]
  • Lijun Shi, Chenguang Yang, Mingyuan Zhang, Kangning Li, Keying Wang, Li Jiao, Ruming Liu, Yunyun Wang, Ming Li, Yong Wang, Lu Ma, Shuxin Hu, Xin Bian. Dissecting the mechanism of atlastin-mediated homotypic membrane fusion at the single-molecule level. Nature communications. 2024 Mar; 15(1):2488. doi: 10.1038/s41467-024-46919-z. [PMID: 38509071]
  • Mengjie Zhu, Nan Wu, Jiayi Zhong, Chen Chen, Wenwen Liu, Yingdang Ren, Xifeng Wang, Huaibing Jin. N6-methyladenosine modification of the mRNA for a key gene in purine nucleotide metabolism regulates virus proliferation in an insect vector. Cell reports. 2024 Feb; 43(2):113821. doi: 10.1016/j.celrep.2024.113821. [PMID: 38368611]
  • Cody Aplin, Richard A Cerione. Probing the mechanism by which the retinal G protein transducin activates its biological effector PDE6. The Journal of biological chemistry. 2023 Dec; 300(2):105608. doi: 10.1016/j.jbc.2023.105608. [PMID: 38159849]
  • Huayin Bao, Wei Wang, Haibo Sun, Jianzhong Chen. Probing mutation-induced conformational transformation of the GTP/M-RAS complex through Gaussian accelerated molecular dynamics simulations. Journal of enzyme inhibition and medicinal chemistry. 2023 Dec; 38(1):2195995. doi: 10.1080/14756366.2023.2195995. [PMID: 37057639]
  • Man Zhang, Wenshuang Wang, Kaixin Liu, Chao Jia, Yuanyuan Hou, Gang Bai. Astragaloside IV protects against lung injury and pulmonary fibrosis in COPD by targeting GTP-GDP domain of RAS and downregulating the RAS/RAF/FoxO signaling pathway. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2023 Nov; 120(?):155066. doi: 10.1016/j.phymed.2023.155066. [PMID: 37690229]
  • Cecilia Rodriguez-Furlan, Ariana Emami, Jaimie M Van Norman. Distinct ADP-ribosylation factor-GTP exchange factors govern the opposite polarity of two receptor kinases. Plant physiology. 2023 Oct; ?(?):. doi: 10.1093/plphys/kiad519. [PMID: 37787604]
  • Junying Li, Xueling Chang, Xiangming Chen, Ruiyu Ma, Renrong Qi, Wei Liu, Yan Li, Yi Wan, Qinqin Qiu, Qiance Shao, Aiqiao Liu, Kai Zhan. Effects of green tea powder on production performance, egg quality, and blood biochemical parameters in laying hens. Poultry science. 2023 Oct; 102(10):102924. doi: 10.1016/j.psj.2023.102924. [PMID: 37542941]
  • Heng Shi, Xinhai Zhao, Peng Qin, Xianling Zhou, Sisi Liu, Chuanchuan Sun, Qiuyu Cao, Shiping Zhu, Shengyun Sun. Green tea polyphenols alleviate kidney injury induced by di(2-ethylhexyl) phthalate in mice. American journal of nephrology. 2023 Sep; ?(?):. doi: 10.1159/000534106. [PMID: 37734331]
  • Yanan Wang, Kun Liu, Meishan Lu, Jiachen Shi, Yong-Jiang Xu, Yuanfa Liu. Comparative evaluation of static and dynamic simulated digestion models. Journal of the science of food and agriculture. 2023 Sep; 103(12):5893-5903. doi: 10.1002/jsfa.12692. [PMID: 37144349]
  • Jahanvi Ganotra, Bhawana Sharma, Brijesh Biswal, Deepak Bhardwaj, Narendra Tuteja. Emerging role of small GTPases and their interactome in plants to combat abiotic and biotic stress. Protoplasma. 2023 Jul; 260(4):1007-1029. doi: 10.1007/s00709-022-01830-6. [PMID: 36525153]
  • Tian-Tian Jiang, Cong-Lan Ji, Li-Jun Yu, Meng-Ke Song, Yan Li, Qiang Liao, Tuo Wei, Opeyemi Joshua Olatunji, Jian Zuo, Jun Han. Resveratrol-induced SIRT1 activation inhibits glycolysis-fueled angiogenesis under rheumatoid arthritis conditions independent of HIF-1α. Inflammation research : official journal of the European Histamine Research Society ... [et al.]. 2023 Apr; ?(?):. doi: 10.1007/s00011-023-01728-w. [PMID: 37016140]
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  • Yongshun Zhou, Fanze Meng, Kai Han, Kaiyue Zhang, Jianfeng Gao, Fulong Chen. Screening and validating of endogenous reference genes in Chlorella sp. TLD 6B under abiotic stress. Scientific reports. 2023 01; 13(1):1555. doi: 10.1038/s41598-023-28311-x. [PMID: 36707665]
  • Yingjie Guo, Huan Zhang, Chen Yan, Birong Shen, Yue Zhang, Xiangyang Guo, Sha Sun, Fan Yu, Jiayun Yan, Ronghe Liu, Qianping Zhang, Di Zhang, Haiyang Liu, Yang Liu, Yaoyao Zhang, Wenlei Li, Jiangyu Qin, He Lv, Zhaoxia Wang, Yun Yuan, Jie-Feng Yang, Ya-Ting Zhong, Song Gao, Bing Zhou, Lei Liu, Deling Kong, Xiaojiang Hao, Junjie Hu, Quan Chen. Small molecule agonist of mitochondrial fusion repairs mitochondrial dysfunction. Nature chemical biology. 2023 Jan; ?(?):. doi: 10.1038/s41589-022-01224-y. [PMID: 36635564]
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  • Huiling Guo, Juan Wang, Su Ren, Lang-Fan Zheng, Yi-Xuan Zhuang, Dong-Lin Li, Hui-Hui Sun, Li-Ying Liu, Changchuan Xie, Ya-Ying Wu, Hong-Rui Wang, Xianming Deng, Peng Li, Tong-Jin Zhao. Targeting EGFR-dependent tumors by disrupting an ARF6-mediated sorting system. Nature communications. 2022 10; 13(1):6004. doi: 10.1038/s41467-022-33788-7. [PMID: 36224181]
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  • Wudtichai Wisuitiprot, Kornkanok Ingkaninan, Sirada Jones, Neti Waranuch. Effect of green tea extract loaded chitosan microparticles on facial skin: A split-face, double-blind, randomized placebo-controlled study. Journal of cosmetic dermatology. 2022 Sep; 21(9):4001-4008. doi: 10.1111/jocd.14707. [PMID: 34965006]
  • Dustin E Bosch, William R Jeck, David P Siderovski. Self-activating G protein α subunits engage seven-transmembrane regulator of G protein signaling (RGS) proteins and a Rho guanine nucleotide exchange factor effector in the amoeba Naegleria fowleri. The Journal of biological chemistry. 2022 08; 298(8):102167. doi: 10.1016/j.jbc.2022.102167. [PMID: 35738399]
  • Kazuhiro Ito, Doshun Ito, Mina Goto, Sae Suzuki, Shinji Masuda, Koh Iba, Kensuke Kusumi. Regulation of ppGpp Synthesis and Its Impact on Chloroplast Biogenesis during Early Leaf Development in Rice. Plant & cell physiology. 2022 Jul; 63(7):919-931. doi: 10.1093/pcp/pcac053. [PMID: 35428891]
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  • Negar Shahsavari, Boyuan Wang, Yu Imai, Miho Mori, Sangkeun Son, Libang Liang, Nils Böhringer, Sylvie Manuse, Michael F Gates, Madeleine Morrissette, Rachel Corsetti, Josh L Espinoza, Chris L Dupont, Michael T Laub, Kim Lewis. A Silent Operon of Photorhabdus luminescens Encodes a Prodrug Mimic of GTP. mBio. 2022 06; 13(3):e0070022. doi: 10.1128/mbio.00700-22. [PMID: 35575547]
  • Giang Pham, Dong-Min Shin, Yoon Kim, Soo-Hwan Kim. Ran-GTP/-GDP-dependent nuclear accumulation of NONEXPRESSOR OF PATHOGENESIS-RELATED GENES1 and TGACG-BINDING FACTOR2 controls salicylic acid-induced leaf senescence. Plant physiology. 2022 06; 189(3):1774-1793. doi: 10.1093/plphys/kiac164. [PMID: 35417014]
  • Bikram D Pant, Seonghee Lee, Hee-Kyung Lee, Nick Krom, Pooja Pant, YoonJeong Jang, Kirankumar S Mysore. Overexpression of Arabidopsis nucleolar GTP-binding 1 (NOG1) proteins confers drought tolerance in rice. Plant physiology. 2022 06; 189(2):988-1004. doi: 10.1093/plphys/kiac078. [PMID: 35260897]
  • Chen Ling, Xingyong Chen, Weihuang Lin, Zhaoyu Geng. Green tea powder inclusion promoted hatchability through increased yolk antioxidant activity. Poultry science. 2022 May; 101(5):101804. doi: 10.1016/j.psj.2022.101804. [PMID: 35325830]
  • Donghua Jin, Miao Jia, Yuxian Xie, Lihua Lin, Hong Qiu, Guoyuan Lu. Impact of klotho on the expression of SRGAP2a in podocytes in diabetic nephropathy. BMC nephrology. 2022 04; 23(1):151. doi: 10.1186/s12882-022-02765-z. [PMID: 35436879]
  • Kiran S Toti, John R Jimah, Veronica Salmaso, Jenny E Hinshaw, Kenneth A Jacobson. Synthesis and Effect of Conformationally Locked Carbocyclic Guanine Nucleotides on Dynamin. Biomolecules. 2022 04; 12(4):. doi: 10.3390/biom12040584. [PMID: 35454173]
  • Kunpeng Liu, Dongbo Qiu, Xue Liang, Yingqi Huang, Yao Wang, Xin Jia, Kun Li, Jingyuan Zhao, Cong Du, Xiusheng Qiu, Jun Cui, Zhendong Xiao, Yunfei Qin, Qi Zhang. Lipotoxicity-induced STING1 activation stimulates MTORC1 and restricts hepatic lipophagy. Autophagy. 2022 04; 18(4):860-876. doi: 10.1080/15548627.2021.1961072. [PMID: 34382907]
  • Sybille Koehler, Johanna Odenthal, Vivian Ludwig, David Unnersjö Jess, Martin Höhne, Christian Jüngst, Ferdi Grawe, Martin Helmstädter, Johanna L Janku, Carsten Bergmann, Peter F Hoyer, H Henning Hagmann, Gerd Walz, Wilhelm Bloch, Carien Niessen, Bernhard Schermer, Andreas Wodarz, Barry Denholm, Thomas Benzing, Sandra Iden, Paul T Brinkkoetter. Scaffold polarity proteins Par3A and Par3B share redundant functions while Par3B acts independent of atypical protein kinase C/Par6 in podocytes to maintain the kidney filtration barrier. Kidney international. 2022 04; 101(4):733-751. doi: 10.1016/j.kint.2021.11.030. [PMID: 34929254]
  • Yachana Jha, Budheswar Dehury, S P Jeevan Kumar, Anurag Chaurasia, Udai B Singh, Manoj Kumar Yadav, U B Angadi, Rajiv Ranjan, Minaketan Tripathy, R B Subramanian, Sunil Kumar, Jesus Simal-Gandara. Delineation of molecular interactions of plant growth promoting bacteria induced β-1,3-glucanases and guanosine triphosphate ligand for antifungal response in rice: a molecular dynamics approach. Molecular biology reports. 2022 Apr; 49(4):2579-2589. doi: 10.1007/s11033-021-07059-5. [PMID: 34914086]
  • Kohsuke Yamada, Toru Hyodo, Syunichiro Urabe, Satomi Haga, Toshio Hosaka. Serum YKL-40 Level is Associated with Geriatric Nutritional Risk Index (GNRI) and γ-GTP in Hemodialysis Patients. The journal of medical investigation : JMI. 2022; 69(1.2):101-106. doi: 10.2152/jmi.69.101. [PMID: 35466129]
  • Hiroshi Senoo, Daisuke Murata, May Wai, Kenta Arai, Wakiko Iwata, Hiromi Sesaki, Miho Iijima. KARATE: PKA-induced KRAS4B-RHOA-mTORC2 supercomplex phosphorylates AKT in insulin signaling and glucose homeostasis. Molecular cell. 2021 11; 81(22):4622-4634.e8. doi: 10.1016/j.molcel.2021.09.001. [PMID: 34551282]
  • Natsumi Maruta, Yuri Trusov, Alan M Jones, Jose R Botella. Heterotrimeric G Proteins in Plants: Canonical and Atypical Gα Subunits. International journal of molecular sciences. 2021 Oct; 22(21):. doi: 10.3390/ijms222111841. [PMID: 34769272]
  • Anna Bianchi-Smiraglia, David W Wolff, Daniel J Marston, Zhiyong Deng, Zhannan Han, Sudha Moparthy, Rebecca M Wombacher, Ashley L Mussell, Shichen Shen, Jialin Chen, Dong-Hyun Yun, Anderson O'Brien Cox, Cristina M Furdui, Edward Hurley, Maria Laura Feltri, Jun Qu, Thomas Hollis, Jules Berlin Nde Kengne, Bernard Fongang, Rui J Sousa, Mikhail E Kandel, Eugene S Kandel, Klaus M Hahn, Mikhail A Nikiforov. Regulation of local GTP availability controls RAC1 activity and cell invasion. Nature communications. 2021 10; 12(1):6091. doi: 10.1038/s41467-021-26324-6. [PMID: 34667203]
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