PIRBUTEROL (BioDeep_00001868118)
Main id: BioDeep_00000002069
代谢物信息卡片
化学式: C12H20N2O3 (240.147385)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C)(C)NCC(C1=NC(=C(C=C1)O)CO)O
InChI: InChI=1S/C12H20N2O3/c1-12(2,3)13-6-11(17)8-4-5-10(16)9(7-15)14-8/h4-5,11,13,15-17H,6-7H2,1-3H3
描述信息
R - Respiratory system > R03 - Drugs for obstructive airway diseases > R03C - Adrenergics for systemic use > R03CC - Selective beta-2-adrenoreceptor agonists
R - Respiratory system > R03 - Drugs for obstructive airway diseases > R03A - Adrenergics, inhalants > R03AC - Selective beta-2-adrenoreceptor agonists
D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D001993 - Bronchodilator Agents
C78273 - Agent Affecting Respiratory System > C29712 - Anti-asthmatic Agent > C319 - Bronchodilator
C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C87053 - Adrenergic Agonist
D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists
D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents
D020011 - Protective Agents > D002316 - Cardiotonic Agents
D002317 - Cardiovascular Agents
同义名列表
1 个代谢物同义名
数据库引用编号
12 个数据库交叉引用编号
- ChEBI: CHEBI:8245
- KEGG: C07807
- KEGGdrug: D08387
- PubChem: 4845
- DrugBank: DB01291
- ChEMBL: CHEMBL1094966
- CAS: 38677-81-5
- CAS: 64856-15-1
- CAS: 38029-10-6
- PubChem: 10009
- NIKKAJI: J16.427E
- RefMet: Pirbuterol
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- H Windom, J Grainger, C Burgess, J Crane, N Pearce, R Beasley. A comparison of the haemodynamic and hypokalaemic effects of inhaled pirbuterol and salbutamol.
The New Zealand medical journal.
1990 Jun; 103(891):259-61. doi:
. [PMID: 1972557] - F Stroman, H Herold, I Szelenyi. Influence of various adrenergic compounds on plasma potassium levels in conscious dogs and anaesthetized domestic pigs.
Arzneimittel-Forschung.
1989 Dec; 39(12):1562-5. doi:
. [PMID: 2576204] - R Canepa-Anson, J R Dawson, P Kuan, P A Poole-Wilson, G C Sutton, B Cockrill, S R Reuben. Differences between acute and long-term metabolic and endocrine effects of oral beta-adrenoceptor agonist therapy with pirbuterol for cardiac failure.
British journal of clinical pharmacology.
1987 Feb; 23(2):173-81. doi:
10.1111/j.1365-2125.1987.tb03026.x. [PMID: 3828194] - V Grassi, S Daniotti, M Schiassi, M Dottorini, C Tantucci. Oral beta 2-selective adrenergic bronchodilators.
International journal of clinical pharmacology research.
1986; 6(2):93-103. doi:
. [PMID: 2873108] - J Brès, A M Clauzel, M C Pistre, H Rachmat, F Bressolle. [Metabolism of beta-adrenergic substances. Therapeutic implications].
Bulletin europeen de physiopathologie respiratoire.
1985 Sep; 21(5):19s-34s. doi:
. [PMID: 2865990] - S F Vatner, D R Knight, T H Hintze. Norepinephrine-induced beta 1-adrenergic peripheral vasodilation in conscious dogs.
The American journal of physiology.
1985 Jul; 249(1 Pt 2):H49-56. doi:
10.1152/ajpheart.1985.249.1.h49. [PMID: 2861749] - O A Smiseth. Effects of the beta-adrenergic receptor agonist pirbuterol on cardiac performance during acute ischaemic left ventricular failure in dogs.
European journal of pharmacology.
1983 Mar; 87(4):379-86. doi:
10.1016/0014-2999(83)90076-6. [PMID: 6133759] - K T Weber, V Andrews, J S Janicki. Cardiotonic agents in the management of chronic cardiac failure.
American heart journal.
1982 Apr; 103(4 Pt 2):639-49. doi:
10.1016/0002-8703(82)90469-0. [PMID: 7064806] - C V Leier, S Nelson, P Huss, J R Bianchine, A Y Olukotun, C R Taylor, D S Salzburg. Intravenous pirbuterol.
Clinical pharmacology and therapeutics.
1982 Jan; 31(1):89-94. doi:
10.1038/clpt.1982.14. [PMID: 7053311] - H V Levinsky, C Breckenridge, R Lough, D A Gonci, H M McIlhenny, S Qureshi. Six month inhalation studies of pirbuterol acetate aerosol in the beagle dog and squirrel monkey.
Fundamental and applied toxicology : official journal of the Society of Toxicology.
1981 Nov; 1(6):426-31. doi:
10.1016/s0272-0590(81)80022-x. [PMID: 7185594] - B Sharma, J Hoback, G S Francis, M Hodges, R W Asinger, J N Cohn, C R Taylor. Pirbuterol: a new oral sympathomimetic amine for the treatment of congestive heart failure.
American heart journal.
1981 Sep; 102(3 Pt 2):533-41. doi:
10.1016/0002-8703(81)90741-9. [PMID: 6115572] - J R Dawson, R Canepa-Anson, P Kuan, N H Whitaker, J Carnie, C Warnes, S R Reuben, P A Poole-Wilson, G C Sutton. Treatment of chronic heart failure with pirbuterol: acute haemodynamic responses.
British medical journal (Clinical research ed.).
1981 May; 282(6274):1423-6. doi:
10.1136/bmj.282.6274.1423. [PMID: 6112039] - J W Constantine, H M McIlhenny, P F Moore. Pharmacokinetics and cardiopulmonary effects in dogs of sublingual pirbuterol, a new bronchodilator.
The Journal of pharmacology and experimental therapeutics.
1979 Mar; 208(3):371-6. doi:
NULL. [PMID: 430357] - N K Burki, L Diamond. Long-term oral bronchodilator therapy of asthma with pirbuterol.
Clinical pharmacology and therapeutics.
1978 Jul; 24(1):84-9. doi:
10.1002/cpt197824184. [PMID: 657723] - F C Falkner, H M McIlhenny. Selected ion monitoring assay for the bronchodilator pirbuterol.
Biomedical mass spectrometry.
1976 Oct; 3(5):207-11. doi:
10.1002/bms.1200030503. [PMID: 974234]