Bio1_001201 (BioDeep_00000865974)

Main id: BioDeep_00000001414

 


代谢物信息卡片


7-[2-[(E,3S)-3-hydroxyoct-1-enyl]-5-keto-1-cyclopentenyl]enanthic acid

化学式: C20H32O4 (336.2300472)
中文名称: PGB1(前列腺素B1)
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCCCCC(C=CC1=C(C(=O)CC1)CCCCCCC(=O)O)O
InChI: InChI=1S/C20H32O4/c1-2-3-6-9-17(21)14-12-16-13-15-19(22)18(16)10-7-4-5-8-11-20(23)24/h12,14,17,21H,2-11,13,15H2,1H3,(H,23,24)/b14-12+/t17-/m0/s1

描述信息

同义名列表

40 个代谢物同义名

7-[2-[(E,3S)-3-hydroxyoct-1-enyl]-5-keto-1-cyclopentenyl]enanthic acid; 7-[2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxo-1-cyclopentenyl]heptanoic acid; 7-[2-[(3S)-3-hydroxyoct-1-enyl]-5-keto-1-cyclopentenyl]enanthic acid; 7-[2-[(3S)-3-hydroxyoct-1-enyl]-5-oxo-1-cyclopentenyl]heptanoic acid; Prosta-8(12),13-dien-1-oic acid, 15-hydroxy-9-oxo-, (13E,15S)-; (13E,15S)-15-Hydroxy-9-oxoprosta-8(12),13-dien-1-Oic acid; 9-oxo-15S-hydroxy-8(12),13E-prostadienoic acid; Prostaglandin- B1; Prostaglandin B1; NCGC00024019-03; NCGC00024019-04; KBioGR_000202; KBioSS_000202; BSPBio_001482; LMFA03010131; KBio2_005338; MLS000069509; KBio3_000403; CBiol_001937; KBio2_002770; KBio2_000202; SMR000058636; KBio3_000404; Bio1_001201; AIDS-003355; CHEBI:27624; Bio2_000682; P5265_SIGMA; Bio1_000712; Bio2_000202; IDI1_033952; Bio1_000223; AIDS003355; 13345-51-2; 13345-42-1; 28548-74-5; 16363-22-7; 1811-73-0; C00959; PGB1



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

4 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Elina Karhu, Janne Isojärvi, Pia Vuorela, Leena Hanski, Adyary Fallarero. Identification of Privileged Antichlamydial Natural Products by a Ligand-Based Strategy. Journal of natural products. 2017 10; 80(10):2602-2608. doi: 10.1021/acs.jnatprod.6b01052. [PMID: 29043803]
  • Joanna M Little, Mika Kurkela, Julia Sonka, Sirkku Jäntti, Raimo Ketola, Stacie Bratton, Moshe Finel, Anna Radominska-Pandya. Glucuronidation of oxidized fatty acids and prostaglandins B1 and E2 by human hepatic and recombinant UDP-glucuronosyltransferases. Journal of lipid research. 2004 Sep; 45(9):1694-703. doi: 10.1194/jlr.m400103-jlr200. [PMID: 15231852]
  • S Itoh, R Lu, Y Bao, J D Morrow, L J Roberts, V L Schuster. Structural determinants of substrates for the prostaglandin transporter PGT. Molecular pharmacology. 1996 Oct; 50(4):738-42. doi: NULL. [PMID: 8863817]
  • T Hishinuma, H Nakamura, K Itoh, Y Ohyama, M Ishibashi, M Mizugaki. Microdetermination of the prostaglandin B1 in human plasma by gas chromatography/selected ion monitoring using [18O]prostaglandin B1 as an internal standard. Prostaglandins. 1995 Apr; 49(4):239-46. doi: 10.1016/0090-6980(95)00016-4. [PMID: 7667505]
  • R Franson, R Raghupathi, M Fry, J Saal, B Vishwanath, S S Ghosh, M D Rosenthal. Inhibition of human phospholipases A2 by cis-unsaturated fatty acids and oligomers of prostaglandin B1. Advances in experimental medicine and biology. 1990; 279(?):219-30. doi: 10.1007/978-1-4613-0651-1_15. [PMID: 2129000]
  • M D Rosenthal, R C Franson. Oligomers of prostaglandin B1 inhibit arachidonic acid mobilization in human neutrophils and endothelial cells. Biochimica et biophysica acta. 1989 Dec; 1006(3):278-86. doi: 10.1016/0005-2760(89)90014-3. [PMID: 2557075]
  • R C Franson, M D Rosenthal. Oligomers of prostaglandin B1 inhibit in vitro phospholipase A2 activity. Biochimica et biophysica acta. 1989 Dec; 1006(3):272-7. doi: 10.1016/0005-2760(89)90013-1. [PMID: 2597672]
  • J D Watkins, J Jarabak. The effect of NaCl intake on 9-ketoprostaglandin reductase activity in the rabbit kidney. Prostaglandins. 1985 Aug; 30(2):335-49. doi: 10.1016/0090-6980(85)90196-0. [PMID: 3901124]
  • K Matsumoto, K Saito, H Fukuda. Centrally specific and GABA-insensitive inhibition of benzodiazepine binding by prostaglandins (A1, A2 and B2). Journal of pharmacobio-dynamics. 1983 Oct; 6(10):784-6. doi: 10.1248/bpb1978.6.784. [PMID: 6319659]
  • M H Wiley, K R Feingold, C Grunfeld, V Quesney-Huneeus, J M Wu. Evidence for cAMP-independent inhibition of S-phase DNA synthesis by prostaglandins. The Journal of biological chemistry. 1983 Jan; 258(1):491-6. doi: . [PMID: 6294110]
  • S Ivanković, S Ivković, V Molnar. [Prostaglandins in the plasma of patients with chronic renal diseases treated with hemodialysis]. Lijecnicki vjesnik. 1982 Jul; 104(7-8):280-2. doi: NULL. [PMID: 6958953]