dioxybenzone (BioDeep_00000858454)
Main id: BioDeep_00000002726
Industrial Pollutants
代谢物信息卡片
化学式: C14H12O4 (244.0736)
中文名称: 二羟苯宗, 2,2'-二羟基-4-甲氧基二苯甲酮
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: COC1=CC(=C(C=C1)C(=O)C2=CC=CC=C2O)O
InChI: InChI=1S/C14H12O4/c1-18-9-6-7-11(13(16)8-9)14(17)10-4-2-3-5-12(10)15/h2-8,15-16H,1H3
描述信息
C1892 - Chemopreventive Agent > C851 - Sunscreen
Same as: D03853
同义名列表
数据库引用编号
12 个数据库交叉引用编号
- ChEBI: CHEBI:34208
- KEGG: C14283
- KEGGdrug: D03853
- KEGGdrug: D89684
- PubChem: 8569
- DrugBank: DB11221
- ChEMBL: CHEMBL1326877
- CAS: 131-53-3
- PubChem: 17395283
- NIKKAJI: J5.560C
- RefMet: Dioxybenzone
- KNApSAcK: 34208
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Tingjie Zhan, Leili Zhang, Shixuan Cui, Weiping Liu, Ruhong Zhou, Shulin Zhuang. Dioxybenzone triggers enhanced estrogenic effect via metabolic activation: in silico, in vitro and in vivo investigation.
Environmental pollution (Barking, Essex : 1987).
2021 Jan; 268(Pt B):115766. doi:
10.1016/j.envpol.2020.115766. [PMID: 33039677] - Jeayoung C Shin, Eunyoung Lee, Seungchan An, Sun Hee Jin, Jaehyoun Ha, Won Jun Choi, Minsoo Noh. Benzophenone-3 and benzophenone-8 exhibit obesogenic activity via peroxisome proliferator-activated receptor γ pathway.
Toxicology in vitro : an international journal published in association with BIBRA.
2020 Sep; 67(?):104886. doi:
10.1016/j.tiv.2020.104886. [PMID: 32407875] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - Marjeta Česen, David Heath, Marko Krivec, Janez Košmrlj, Tina Kosjek, Ester Heath. Seasonal and spatial variations in the occurrence, mass loadings and removal of compounds of emerging concern in the Slovene aqueous environment and environmental risk assessment.
Environmental pollution (Barking, Essex : 1987).
2018 Nov; 242(Pt A):143-154. doi:
10.1016/j.envpol.2018.06.052. [PMID: 29966838] - Sukyoung Heo, Hee Sook Hwang, Yohan Jeong, Kun Na. Skin protection efficacy from UV irradiation and skin penetration property of polysaccharide-benzophenone conjugates as a sunscreen agent.
Carbohydrate polymers.
2018 Sep; 195(?):534-541. doi:
10.1016/j.carbpol.2018.05.010. [PMID: 29805009] - Huixiao Hong, William S Branham, Hui Wen Ng, Carrie L Moland, Stacey L Dial, Hong Fang, Roger Perkins, Daniel Sheehan, Weida Tong. Human sex hormone-binding globulin binding affinities of 125 structurally diverse chemicals and comparison with their binding to androgen receptor, estrogen receptor, and α-fetoprotein.
Toxicological sciences : an official journal of the Society of Toxicology.
2015 Feb; 143(2):333-48. doi:
10.1093/toxsci/kfu231. [PMID: 25349334] - Huixiao Hong, William S Branham, Stacey L Dial, Carrie L Moland, Hong Fang, Jie Shen, Roger Perkins, Daniel Sheehan, Weida Tong. Rat α-Fetoprotein binding affinities of a large set of structurally diverse chemicals elucidated the relationships between structures and binding affinities.
Chemical research in toxicology.
2012 Nov; 25(11):2553-66. doi:
10.1021/tx3003406. [PMID: 23013281]
