N-Methylanthranilic acid (BioDeep_00000405938)

Main id: BioDeep_00000003149

Secondary id: BioDeep_00000864112

natural product PANOMIX_OTCML-2023


代谢物信息卡片


N-Methylanthranilic acid

化学式: C8H9NO2 (151.0633)
中文名称: N-甲基邻氨基苯甲酸
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 13.56%

分子结构信息

SMILES: CNC1=CC=CC=C1C(=O)O
InChI: InChI=1S/C8H9NO2/c1-9-7-5-3-2-4-6(7)8(10)11/h2-5,9H,1H3,(H,10,11)

描述信息

An aromatic amino acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is substituted by a methyl group.
2-(Methylamino)benzoic acid is the main metabolite of methyl-N-methylanthranilates (MMA) (HY-76705) and is the compound in which the ester group is converted. MMA can be isolated from citrus fruits and has potential analgesic activity. 2-(Methylamino)benzoic acid was used to detect the metabolic levels of MMA in rat liver[1].

同义名列表

4 个代谢物同义名

N-Methylanthranilic acid; 2-(Methylamino)benzoic acid; N-Methylanthranilate; N-Methylanthranilic acid



数据库引用编号

36 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

37 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 3 ACE, HTT, PTGS2
Peripheral membrane protein 2 CYP1B1, PTGS2
Endosome membrane 1 HTT
Endoplasmic reticulum membrane 2 CYP1B1, PTGS2
Nucleus 1 HTT
autophagosome 1 HTT
cytosol 1 HTT
dendrite 1 HTT
nucleoplasm 1 HTT
Cell membrane 2 ACE, HTT
Multi-pass membrane protein 1 HTT
Synapse 1 HTT
Golgi apparatus 1 HTT
presynaptic membrane 1 HTT
Lysosome 1 ACE
endosome 1 ACE
plasma membrane 2 ACE, HTT
Membrane 2 ACE, CYP1B1
axon 1 HTT
caveola 1 PTGS2
extracellular exosome 2 ACE, CPVL
endoplasmic reticulum 2 HTT, PTGS2
extracellular space 2 ACE, MMP1
perinuclear region of cytoplasm 1 HTT
mitochondrion 1 CYP1B1
protein-containing complex 2 HTT, PTGS2
intracellular membrane-bounded organelle 1 CYP1B1
Microsome membrane 2 CYP1B1, PTGS2
Single-pass type I membrane protein 1 ACE
Secreted 1 ACE
extracellular region 2 ACE, MMP1
external side of plasma membrane 1 ACE
Secreted, extracellular space, extracellular matrix 1 MMP1
Early endosome 1 HTT
postsynaptic membrane 1 HTT
Membrane raft 1 HTT
Cell junction, focal adhesion 1 HTT
focal adhesion 1 HTT
extracellular matrix 1 MMP1
Nucleus inner membrane 1 PTGS2
Nucleus outer membrane 1 PTGS2
nuclear inner membrane 1 PTGS2
nuclear outer membrane 1 PTGS2
Late endosome 1 HTT
Cell projection, neuron projection 1 HTT
neuron projection 2 HTT, PTGS2
centriole 1 HTT
brush border membrane 1 ACE
sperm midpiece 1 ACE
Endomembrane system 1 HTT
Cytoplasmic vesicle membrane 1 HTT
basal plasma membrane 1 ACE
endoplasmic reticulum lumen 1 PTGS2
postsynaptic cytosol 1 HTT
presynaptic cytosol 1 HTT
inclusion body 1 HTT
[Angiotensin-converting enzyme, soluble form]: Secreted 1 ACE
[Isoform Testis-specific]: Cell membrane 1 ACE
serotonergic synapse 1 HTT
[Huntingtin]: Cytoplasm 1 HTT
[Huntingtin, myristoylated N-terminal fragment]: Cytoplasmic vesicle, autophagosome 1 HTT


文献列表

  • P Guedes De Pinho, Rui F Gonçalves, Patrícia Valentão, David M Pereira, Rosa M Seabra, Paula B Andrade, Mariana Sottomayor. Volatile composition of Catharanthus roseus (L.) G. Don using solid-phase microextraction and gas chromatography/mass spectrometry. Journal of pharmaceutical and biomedical analysis. 2009 Apr; 49(3):674-85. doi: 10.1016/j.jpba.2008.12.032. [PMID: 19186019]
  • Alexander Endler, Stefan Martens, Frank Wellmann, Ulrich Matern. Unusually divergent 4-coumarate:CoA-ligases from Ruta graveolens L. Plant molecular biology. 2008 Jul; 67(4):335-46. doi: 10.1007/s11103-008-9323-7. [PMID: 18379886]
  • Jihong Wang, Vincenzo De Luca. The biosynthesis and regulation of biosynthesis of Concord grape fruit esters, including 'foxy' methylanthranilate. The Plant journal : for cell and molecular biology. 2005 Nov; 44(4):606-19. doi: 10.1111/j.1365-313x.2005.02552.x. [PMID: 16262710]
  • Maique W Biavatti, Paulo C Vieira, M Fátima G F Da Silva, João B Fernandes, Sérgio Albuquerque. Triterpenoid constituents of Raulinoa echinata. Journal of natural products. 2002 Apr; 65(4):562-5. doi: 10.1021/np0103970. [PMID: 11975501]