L-Pyroglutamicacid (BioDeep_00000399909)

Main id: BioDeep_00000001870

 

natural product PANOMIX_OTCML-2023 BioNovoGene_Lab2019


代谢物信息卡片


L-Pyroglutamic acid

化学式: C5H7NO3 (129.0426)
中文名称: L-焦谷氨酸
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1CC(=O)NC1C(=O)O
InChI: InChI=1S/C5H7NO3/c7-4-2-1-3(6-4)5(8)9/h3H,1-2H2,(H,6,7)(H,8,9)/t3-/m0/s1

描述信息

C78276 - Agent Affecting Digestive System or Metabolism > C29703 - Antilipidemic Agent

同义名列表

5 个代谢物同义名

L-Pyroglutamic acid; L-Pyroglutamicacid; 5-oxo-L-Proline; 5-Oxoproline; L-Pyroglutamic acid



数据库引用编号

20 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

21 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 4 ACE, CA1, PGPEP1, TRHDE
Endosome membrane 1 ITM2B
Nucleus 2 EHMT2, FLG
cytosol 5 CA1, FLG, GLS, GSS, PGPEP1
nucleoplasm 2 EHMT2, SLC3A2
Cell membrane 4 ACE, ITM2B, SLC3A2, TNF
Cytoplasmic granule 1 FLG
Golgi apparatus membrane 2 ITM2B, QPCTL
Synapse 2 GLS, SLC3A2
cell junction 1 SLC3A2
cell surface 2 SLC3A2, TNF
glutamatergic synapse 1 FLG
Golgi apparatus 2 ITM2B, QPCTL
Golgi membrane 3 INS, ITM2B, QPCTL
lysosomal membrane 1 SLC3A2
neuronal cell body 1 TNF
postsynapse 1 FLG
Cytoplasm, cytosol 1 GLS
Cytoplasmic vesicle, secretory vesicle 2 CHGA, NTS
Lysosome 1 ACE
endosome 1 ACE
plasma membrane 7 ACE, FLG, ITM2B, KNG1, SLC3A2, TNF, TRHDE
Membrane 6 ACE, FLG, ITM2B, QPCTL, SLC3A2, TRHDE
apical plasma membrane 1 SLC3A2
basolateral plasma membrane 1 SLC3A2
extracellular exosome 8 ACE, CA1, GSS, ITM2B, KNG1, QPCT, SLC3A2, TRHDE
Lysosome membrane 1 SLC3A2
extracellular space 8 ACE, CCL2, CHGA, INS, ITM2B, KNG1, TNF, TRHDE
perinuclear region of cytoplasm 1 CHGA
mitochondrion 1 GLS
intracellular membrane-bounded organelle 2 ITM2B, NTS
Single-pass type I membrane protein 2 ACE, QPCTL
Secreted 7 ACE, CCL2, CHGA, INS, NTS, QPCT, TRH
extracellular region 11 ACE, CCL2, CHGA, FLG, INS, ITM2B, KNG1, NTS, QPCT, TNF, TRH
mitochondrial matrix 1 GLS
anchoring junction 1 SLC3A2
external side of plasma membrane 2 ACE, TNF
cytoplasmic vesicle 1 FLG
recycling endosome 1 TNF
Single-pass type II membrane protein 3 ITM2B, SLC3A2, TNF
Apical cell membrane 1 SLC3A2
Membrane raft 1 TNF
cis-Golgi network 1 GOLGA6A
collagen-containing extracellular matrix 2 FLG, KNG1
secretory granule 2 CHGA, TRH
nuclear speck 1 EHMT2
receptor complex 1 FLG
chromatin 1 EHMT2
phagocytic cup 1 TNF
Chromosome 1 EHMT2
cytoplasmic ribonucleoprotein granule 1 FLG
Secreted, extracellular space 1 KNG1
[Isoform 1]: Mitochondrion 1 GLS
brush border membrane 1 ACE
blood microparticle 1 KNG1
sperm midpiece 1 ACE
Basolateral cell membrane 1 SLC3A2
organelle membrane 1 ITM2B
endosome lumen 1 INS
Cornified envelope 1 FLG
Melanosome 1 SLC3A2
Golgi cisterna membrane 1 GOLGA6A
Golgi-associated vesicle membrane 1 ITM2B
basal plasma membrane 2 ACE, SLC3A2
ficolin-1-rich granule lumen 1 QPCT
secretory granule lumen 1 INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 2 INS, KNG1
platelet alpha granule lumen 1 KNG1
axon terminus 1 NTS
specific granule lumen 1 QPCT
tertiary granule lumen 1 QPCT
transport vesicle 3 CHGA, INS, NTS
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
neuronal dense core vesicle 1 CHGA
[Isoform 3]: Mitochondrion 1 GLS
[Glutaminase kidney isoform, mitochondrial 68 kDa chain]: Mitochondrion matrix 1 GLS
[Glutaminase kidney isoform, mitochondrial 65 kDa chain]: Mitochondrion matrix 1 GLS
Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle 1 CHGA
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
chromaffin granule 1 CHGA
amino acid transport complex 1 SLC3A2
apical pole of neuron 1 SLC3A2
keratohyalin granule 1 FLG
[Serpinin]: Secreted 1 CHGA
[Angiotensin-converting enzyme, soluble form]: Secreted 1 ACE
[Isoform Testis-specific]: Cell membrane 1 ACE
Golgi cis cisterna 1 GOLGA6A
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF
[Integral membrane protein 2B]: Golgi apparatus membrane 1 ITM2B
[BRI2, membrane form]: Cell membrane 1 ITM2B
[Bri23 peptide]: Secreted 1 ITM2B
[BRI2C, soluble form]: Secreted 1 ITM2B


文献列表

  • Shixiong Jiang, Heather G Marco, Nina Scheich, Shulin He, Zongqing Wang, Gerd Gäde, Dino P McMahon. Comparative analysis of adipokinetic hormones and their receptors in Blattodea reveals novel patterns of gene evolution. Insect molecular biology. 2023 12; 32(6):615-633. doi: 10.1111/imb.12861. [PMID: 37382487]
  • Xiaoyan Yang, Dongqun Xu, Bo Wen, Jian Ji, Zeyu Zhang, Li Li, Shaoping Zhang, Hong Zhi, Jian Kong, Chong Wang, Jun Wang, Hongjie Ruan, Ming Zhang, Lan Wei, Bin Dong, Qin Wang. The mediating role of exhaled breath condensate metabolites in the effect of particulate matter on pulmonary function in schoolchildren: A crossover intervention study. The Science of the total environment. 2023 Jul; 898(?):165517. doi: 10.1016/j.scitotenv.2023.165517. [PMID: 37459994]
  • Pat J Unkefer, Thomas J Knight, Rodolfo A Martinez. The intermediate in a nitrate-responsive ω-amidase pathway in plants may signal ammonium assimilation status. Plant physiology. 2023 01; 191(1):715-728. doi: 10.1093/plphys/kiac501. [PMID: 36303326]
  • Rui-Kun Zhang, Kun Yan, Hai-Feng Chen, Yang Zhang, Gui-Jin Li, Xiao-Gang Chen, Lin-Pu Ge, Feng Cheng, Zhi-Neng Chen, Xin-Miao Yao. Anti-osteoporotic drugs affect the pathogenesis of gut microbiota and its metabolites: a clinical study. Frontiers in cellular and infection microbiology. 2023; 13(?):1091083. doi: 10.3389/fcimb.2023.1091083. [PMID: 37475958]
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