Triacetic acid (BioDeep_00000004750)

 

Secondary id: BioDeep_00001869868

human metabolite blood metabolite


代谢物信息卡片


3,5-Dioxo-hexanoic acid

化学式: C6H8O4 (144.0423)
中文名称:
谱图信息: 最多检出来源 Homo sapiens(plant) 9.04%

分子结构信息

SMILES: CC(=O)CC(=O)CC(=O)O
InChI: InChI=1S/C6H8O4/c1-4(7)2-5(8)3-6(9)10/h2-3H2,1H3,(H,9,10)



数据库引用编号

14 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 13 ABCB1, ALB, BCL2L1, BGLAP, CASP9, CAT, EGFR, FDPS, FOLH1, G6PD, ITPR3, MCL1, MSMP
Peripheral membrane protein 1 G6PD
Endosome membrane 1 EGFR
Endoplasmic reticulum membrane 2 EGFR, ITPR3
Mitochondrion membrane 1 BCL2L1
Nucleus 5 ALB, CASP9, EGFR, MCL1, NR1I2
cytosol 9 ALB, BCL2L1, CASP9, CAT, FDPS, G6PD, MB, MCL1, SST
dendrite 2 BGLAP, TACR1
nuclear body 1 NR1I2
centrosome 2 ALB, BCL2L1
nucleoplasm 4 FDPS, ITPR3, MCL1, NR1I2
Cell membrane 4 ABCB1, EGFR, FOLH1, TACR1
Cytoplasmic side 1 BCL2L1
ruffle membrane 1 EGFR
Early endosome membrane 1 EGFR
Multi-pass membrane protein 3 ABCB1, ITPR3, TACR1
cell junction 1 EGFR
cell surface 4 ABCB1, EGFR, FOLH1, TACR1
glutamatergic synapse 1 EGFR
Golgi apparatus 1 ALB
Golgi membrane 1 EGFR
mitochondrial inner membrane 1 BCL2L1
neuronal cell body 2 ITPR3, SST
Cytoplasm, cytosol 2 BCL2L1, G6PD
endosome 1 EGFR
plasma membrane 6 ABCB1, EGFR, ERBB3, FOLH1, ITPR3, TACR1
synaptic vesicle membrane 1 BCL2L1
Membrane 9 ABCB1, CAT, EGFR, ERBB3, FDPS, FOLH1, G6PD, ITPR3, MCL1
apical plasma membrane 3 ABCB1, EGFR, ERBB3
basolateral plasma membrane 2 EGFR, ERBB3
brush border 1 ITPR3
extracellular exosome 6 ABCB1, ALB, CAT, FOLH1, G6PD, MB
endoplasmic reticulum 3 ALB, BCL2L1, ITPR3
extracellular space 7 ALB, BGLAP, EGFR, ERBB3, IL6, MSMP, SST
perinuclear region of cytoplasm 1 EGFR
mitochondrion 5 BCL2L1, CASP9, CAT, MCL1, OXCT1
protein-containing complex 4 ALB, CASP9, CAT, EGFR
intracellular membrane-bounded organelle 2 CAT, G6PD
Single-pass type I membrane protein 2 EGFR, ERBB3
Secreted 5 ALB, BGLAP, IL6, MSMP, SST
extracellular region 5 ALB, BGLAP, CAT, IL6, SST
cytoplasmic side of plasma membrane 1 G6PD
Mitochondrion outer membrane 1 BCL2L1
Single-pass membrane protein 2 BCL2L1, MCL1
mitochondrial outer membrane 2 BCL2L1, MCL1
Mitochondrion matrix 1 BCL2L1
mitochondrial matrix 4 BCL2L1, CAT, FDPS, OXCT1
anchoring junction 1 ALB
transcription regulator complex 1 NR1I2
centriolar satellite 1 G6PD
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome 1 BCL2L1
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 BCL2L1
Nucleus membrane 1 BCL2L1
Bcl-2 family protein complex 2 BCL2L1, MCL1
nuclear membrane 2 BCL2L1, EGFR
perikaryon 1 BGLAP
nucleolus 1 ITPR3
sarcoplasm 1 MB
apical part of cell 1 ITPR3
Single-pass type II membrane protein 1 FOLH1
vesicle 1 BGLAP
postsynaptic membrane 1 TACR1
Apical cell membrane 1 ABCB1
Membrane raft 1 EGFR
focal adhesion 2 CAT, EGFR
GABA-ergic synapse 1 SST
Peroxisome 2 CAT, FDPS
intracellular vesicle 1 EGFR
sarcoplasmic reticulum 1 ITPR3
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
lateral plasma membrane 1 ERBB3
nuclear outer membrane 1 ITPR3
receptor complex 3 EGFR, ERBB3, ITPR3
ciliary basal body 1 ALB
chromatin 1 NR1I2
centriole 1 ALB
spindle pole 1 ALB
blood microparticle 1 ALB
sperm midpiece 1 TACR1
sperm flagellum 1 TACR1
myosin complex 1 MCL1
Nucleus, nucleoplasm 1 MCL1
cell body 1 TACR1
intermediate filament cytoskeleton 1 NR1I2
basal plasma membrane 2 EGFR, ERBB3
synaptic membrane 1 EGFR
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 1 CAT
secretory granule membrane 1 ITPR3
Golgi lumen 1 BGLAP
endoplasmic reticulum lumen 3 ALB, BGLAP, IL6
platelet alpha granule lumen 1 ALB
neuronal dense core vesicle 1 SST
apoptosome 1 CASP9
clathrin-coated endocytic vesicle membrane 1 EGFR
platelet dense tubular network membrane 1 ITPR3
external side of apical plasma membrane 1 ABCB1
[Isoform 1]: Cell membrane 1 ERBB3
Cytoplasmic vesicle, secretory vesicle membrane 1 ITPR3
multivesicular body, internal vesicle lumen 1 EGFR
Shc-EGFR complex 1 EGFR
transport vesicle membrane 1 ITPR3
Cytoplasm, sarcoplasm 1 MB
catalase complex 1 CAT
sperm head 1 TACR1
ERBB3:ERBB2 complex 1 ERBB3
interleukin-6 receptor complex 1 IL6
cytoplasmic side of endoplasmic reticulum membrane 1 ITPR3
ciliary transition fiber 1 ALB
caspase complex 1 CASP9
[Isoform PSMA']: Cytoplasm 1 FOLH1
[Isoform Bcl-X(L)]: Mitochondrion inner membrane 1 BCL2L1


文献列表

  • V Mallika, K C Sivakumar, E V Soniya. Evolutionary Implications and Physicochemical Analyses of Selected Proteins of Type III Polyketide Synthase Family. Evolutionary bioinformatics online. 2011; 7(?):41-53. doi: 10.4137/ebo.s6854. [PMID: 21697991]
  • Ikuro Abe, Tatsuya Watanabe, Weiwei Lou, Hiroshi Noguchi. Active site residues governing substrate selectivity and polyketide chain length in aloesone synthase. The FEBS journal. 2006 Jan; 273(1):208-18. doi: 10.1111/j.1742-4658.2005.05059.x. [PMID: 16367761]
  • Hyun-soon Chong, Kayhan Garmestani, Dangshe Ma, Diane E Milenic, Terrish Overstreet, Martin W Brechbiel. Synthesis and biological evaluation of novel macrocyclic ligands with pendent donor groups as potential yttrium chelators for radioimmunotherapy with improved complex formation kinetics. Journal of medicinal chemistry. 2002 Aug; 45(16):3458-64. doi: 10.1021/jm0200759. [PMID: 12139456]