Lufenuron (BioDeep_00000003639)

human metabolite blood metabolite

代谢物信息卡片

1-[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]-3-[(2,6-difluorophenyl)(hydroxy)methylidene]urea

化学式: C17H8Cl2F8N2O3 (509.9784214)
中文名称: 虱螨脲
谱图信息: 最多检出来源 Bos taurus(blood) 15.87%

分子结构信息

SMILES: C1=CC(=C(C(=C1)F)C(=O)NC(=O)NC2=CC(=C(C=C2Cl)OC(C(C(F)(F)F)F)(F)F)Cl)F
InChI: InChI=1S/C17H8Cl2F8N2O3/c18-6-5-11(32-17(26,27)14(22)16(23,24)25)7(19)4-10(6)28-15(31)29-13(30)12-8(20)2-1-3-9(12)21/h1-5,14H,(H2,28,29,30,31)

描述信息

CONFIDENCE standard compound; INTERNAL_ID 195; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4912; ORIGINAL_PRECURSOR_SCAN_NO 4910
CONFIDENCE standard compound; INTERNAL_ID 195; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4941; ORIGINAL_PRECURSOR_SCAN_NO 4937
CONFIDENCE standard compound; INTERNAL_ID 195; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4954; ORIGINAL_PRECURSOR_SCAN_NO 4953
CONFIDENCE standard compound; INTERNAL_ID 195; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4964; ORIGINAL_PRECURSOR_SCAN_NO 4962
CONFIDENCE standard compound; INTERNAL_ID 195; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4913; ORIGINAL_PRECURSOR_SCAN_NO 4912
CONFIDENCE standard compound; INTERNAL_ID 195; DATASET 20200303_ENTACT_RP_MIX501; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4945; ORIGINAL_PRECURSOR_SCAN_NO 4943
D010575 - Pesticides > D007306 - Insecticides
D016573 - Agrochemicals

同义名列表

9 个代谢物同义名

1-[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]-3-[(2,6-difluorophenyl)(hydroxy)methylidene]urea; N-({[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]amino}carbonyl)-2,6-difluorobenzamide; N-(2,5-dichloro-4-(1,1,2,3,3,3-Hexafluoropropoxy)phenylaminocarbonyl)-2,6-difluorobenzamide; 1-(2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl)-3-(2,6-difluorobenzoyl)urea; Fluphenacur, monosodium salt; Fluphenacur; Lufenuron; Program; Lufenuron

数据库引用编号

23 个数据库交叉引用编号

ChEBI: CHEBI:39384
KEGG: C18434
KEGGdrug: D08150
PubChem: 71777
HMDB: HMDB0254195
Metlin: METLIN72241
DrugBank: DB11424
ChEMBL: CHEMBL1364906
Wikipedia: Lufenuron
chemspider: 64813
CAS: 103055-07-8
CAS: 130841-26-8
CAS: 130841-22-4
MoNA: LU019554
MoNA: LU019552
MoNA: LU019555
MoNA: LU019556
MoNA: LU019551
MoNA: LU019553
PMhub: MS000010688
PubChem: 124489108
RefMet: Lufenuron
KNApSAcK: 39384

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

9606 - Homo sapiens: -

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Meng-Hao Xia, Deng Pan, Chuan-Zhen Li, Yu-Chuang Li, Wei Dou, Jin-Jun Wang. Sublethal and transgenerational effects of lufenuron on the biological traits of Panonychus citri (McGregor) (Acari: Tetranychidae). Pesticide biochemistry and physiology. 2024 Jan; 198(?):105727. doi: 10.1016/j.pestbp.2023.105727. [PMID: 38225066]
Xiaoyao Wang, Shuai Hu, Lingtao Meng, Kai Wang, Xianxia Zhang, Ke Li, Ning Wang, Nan Zou, Yue Xu, Beixing Li, Wei Mu, Xiuyu Pang. Residue dissipation dynamics and dietary risk assessment of emamectin benzoate, chlorantraniliprole, chlorfenapyr, and lufenuron in cabbage. Environmental science and pollution research international. 2023 Nov; ?(?):. doi: 10.1007/s11356-023-30919-5. [PMID: 37955734]
Yanhui Lu, Junce Tian, Farman Ullah, Nicolas Desneux, Jiawen Guo, Shanshan Wang, Hongxing Xu, Zhongxian Lu. Sublethal and transgenerational effects of lufenuron on biological characteristics and expression of reproductive related genes in the fall armyworm, Spodoptera frugiperda. Pesticide biochemistry and physiology. 2023 Nov; 196(?):105593. doi: 10.1016/j.pestbp.2023.105593. [PMID: 37945243]
Qianwei Liang, Chaoqun Hou, Yifei Tan, Nuo Wei, Shaoyang Sun, Shengfu Zhang, Jianguo Feng. Construction and biological effects of a redox-enzyme dual-responsive lufenuron nano-controlled release formulation. Pest management science. 2023 Oct; ?(?):. doi: 10.1002/ps.7862. [PMID: 37903714]
Guodong Zhu, Wenjuan Ding, Yongfei Zhao, Ming Xue, Haipeng Zhao, Shouzhu Liu. Biological and physiological responses of two Bradysia pests, Bradysia odoriphaga and Bradysia difformis, to Dinotefuran and Lufenuron. Pesticide biochemistry and physiology. 2023 Feb; 190(?):105338. doi: 10.1016/j.pestbp.2023.105338. [PMID: 36740337]
Haixiang Lv, Shanshan Ling, Zhimin Guo, Chengfeng Zheng, Huina Ma, Jianhong Li, Kangsheng Ma. Effects of lufenuron treatments on the growth and development of Spodoptera frugiperda (Lepidoptera: Noctuidae). Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 2023 Jan; 263(?):109499. doi: 10.1016/j.cbpc.2022.109499. [PMID: 36336329]
M A Mahmoud, I E AbdElrahman, O A A Zedan, Y A Abdel-Rahman, R M Saba, G F Abo Laban, I S Ibrahim. Effect of three insect growth regulators on certain biological aspects of the lesser grain borer, Rhyzopertha dominica (Coleoptera: Bostrichidae). Brazilian journal of biology = Revista brasleira de biologia. 2023; 82(?):e267629. doi: 10.1590/1519-6984.267629. [PMID: 36651458]
Xi Cheng, Jinjing Xiao, Yuanhui Liu, Qun Gao, Qingkui Fang, Min Liao, Bing Liang, Zhendi Hu, Haiqun Cao. Effect of formulation on the indoxacarb and lufenuron dissipation in maize and risk assessment. Environmental science and pollution research international. 2022 Oct; 29(47):70976-70983. doi: 10.1007/s11356-022-20719-8. [PMID: 35595890]
Wesam T Basal, Abdel Rahman T Ahmed, Aya A Mahmoud, Amel R Omar. Lufenuron induces reproductive toxicity and genotoxic effects in pregnant albino rats and their fetuses. Scientific reports. 2020 11; 10(1):19544. doi: 10.1038/s41598-020-76638-6. [PMID: 33177580]
Regis F Stacke, Daniela N Godoy, Venicius E Pretto, Fábio M Führ, Patricia da S Gubiani, Bruna L Hettwer, Cínthia G Garlet, Junior C Somavilla, Dionei S Muraro, Oderlei Bernardi. Field-evolved resistance to chitin synthesis inhibitor insecticides by soybean looper, Chrysodeixis includens (Lepidoptera: Noctuidae), in Brazil. Chemosphere. 2020 Nov; 259(?):127499. doi: 10.1016/j.chemosphere.2020.127499. [PMID: 32629314]
Ali Taheri Mirghaed, Melika Baes, Seyyed Morteza Hoseini. Humoral immune responses and gill antioxidant-related gene expression of common carp (Cyprinus carpio) exposed to lufenuron and flonicamide. Fish physiology and biochemistry. 2020 Apr; 46(2):739-746. doi: 10.1007/s10695-019-00747-x. [PMID: 31848827]
Muhammad Hafeez, Saad Jan, Muhammad Nawaz, Ehsan Ali, Bahar Ali, Muhammad Qasim, G Mandela Fernández-Grandon, Muhammad Shahid, Mo Wang. Sub-lethal effects of lufenuron exposure on spotted bollworm Earias vittella (Fab): key biological traits and detoxification enzymes activity. Environmental science and pollution research international. 2019 May; 26(14):14300-14312. doi: 10.1007/s11356-019-04655-8. [PMID: 30864030]
R S Silva, L P Arcanjo, J R S Soares, D O Ferreira, J E Serrão, J C Martins, Á H Costa, M C Picanço. Insecticide toxicity to the borer Neoleucinodes elegantalis (Guenée) (Lepidoptera: Crambidae): developmental and egg-laying effects. Neotropical entomology. 2018 Apr; 47(2):318-325. doi: 10.1007/s13744-017-0553-8. [PMID: 28822099]
Fangyuan Zhou, Guodong Zhu, Haipeng Zhao, Zheng Wang, Ming Xue, Xianxian Li, Huaqiang Xu, Xiaodan Ma, Yanyan Liu. Sterilization Effects of Adult-targeted Baits Containing Insect Growth Regulators on Delia antiqua. Scientific reports. 2016 09; 6(?):32855. doi: 10.1038/srep32855. [PMID: 27619006]
Bizhang Dong, Qing Zhao, Jiye Hu. Dissipation kinetics of emamectin benzoate and lufenuron residues in cabbage grown under field conditions. Environmental monitoring and assessment. 2015 Dec; 187(12):765. doi: 10.1007/s10661-015-4989-1. [PMID: 26590145]
M M Parrilla Vázquez, P Parrilla Vázquez, M Martínez Galera, A Uclés Moreno. Comparison of two ionic liquid dispersive liquid-liquid microextraction approaches for the determination of benzoylurea insecticides in wastewater using liquid chromatography-quadrupole-linear ion trap-mass spectrometry: evaluation of green parameters. Journal of chromatography. A. 2014 Aug; 1356(?):1-9. doi: 10.1016/j.chroma.2014.06.032. [PMID: 24993054]
Ismael Sánchez-Ramos, Cristina E Fernández, Manuel González-Núñez, Susana Pascual. Laboratory tests of insect growth regulators as bait sprays for the control of the olive fruit fly, Bactrocera oleae (Diptera: Tephritidae). Pest management science. 2013 Apr; 69(4):520-6. doi: 10.1002/ps.3403. [PMID: 23034882]
Mingrong Qian, Liqin Wu, Hu Zhang, Mingfei Xu, Rui Li, Xiangyun Wang, Caixia Sun. Determination of 16 insect growth regulators in edible Chinese traditional herbs by liquid chromatography electrospray tandem mass spectrometry. Analytical and bioanalytical chemistry. 2012 Mar; 402(7):2451-62. doi: 10.1007/s00216-011-5699-3. [PMID: 22271101]
Simin Khajepour, Hamzeh Izadi, Mohammad Javad Asari. Evaluation of two formulated chitin synthesis inhibitors, hexaflumuron and lufenuron against the raisin moth, Ephestia figulilella. Journal of insect science (Online). 2012; 12(?):102. doi: 10.1673/031.012.10201. [PMID: 23425138]
F Erler, E Polat, H Demir, M Catal, G Tuna. Control of mushroom sciarid fly Lycoriella ingenua populations with insect growth regulators applied by soil drench. Journal of economic entomology. 2011 Jun; 104(3):839-44. doi: 10.1603/ec10292. [PMID: 21735902]
V A Vassiliou. Effectiveness of insecticides in controlling the first and second generations of the Lobesia botrana (Lepidoptera: Tortricidae) in table grapes. Journal of economic entomology. 2011 Apr; 104(2):580-5. doi: 10.1603/ec10343. [PMID: 21510208]
Ahmad Hanafi, Vincenzo L Garau, Pierluigi Caboni, Giorgia Sarais, Paolo Cabras. Minor crops for export: a case study of boscalid, pyraclostrobin, lufenuron and lambda-cyhalothrin residue levels on green beans and spring onions in Egypt. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes. 2010 Aug; 45(6):493-500. doi: 10.1080/03601234.2010.493466. [PMID: 20574869]
Atef M Al-Attar. Physiological and histopathological investigations on the effects of alpha-lipoic acid in rats exposed to malathion. Journal of biomedicine & biotechnology. 2010; 2010(?):203503. doi: 10.1155/2010/203503. [PMID: 20454535]
S Khadiga Moursi, A S H Abo-Shanab, H A Mesbah, S I Abdel-Razak, A K Mourad, O A Zaghloul, R S Abdel-Fatah. Efficacy of some oils and chemical compounds on Insignorthezia insignis (Browne) (Hemiptera: Ortheziidae) infesting Lantana camara in Alexandria, Egypt. Communications in agricultural and applied biological sciences. 2010; 75(3):345-57. doi: ". [PMID: 21539253]
Umesh Gangishetti, Sophie Breitenbach, Mareike Zander, Shaik Khaleelulla Saheb, Ursula Müller, Heinz Schwarz, Bernard Moussian. Effects of benzoylphenylurea on chitin synthesis and orientation in the cuticle of the Drosophila larva. European journal of cell biology. 2009 Mar; 88(3):167-80. doi: 10.1016/j.ejcb.2008.09.002. [PMID: 18996617]
S Khay, J H Choi, A M Abd El-Aty, M I R Mamun, B J Park, A Goudah, H C Shin, J H Shim. Dissipation behavior of lufenuron, benzoylphenylurea insecticide, in/on Chinese cabbage applied by foliar spraying under greenhouse conditions. Bulletin of environmental contamination and toxicology. 2008 Oct; 81(4):369-72. doi: 10.1007/s00128-008-9490-x. [PMID: 18592122]
R Karimzadeh, M J Hejazi, F Rahimzadeh Khoei, M Moghaddam. Laboratory evaluation of five chitin synthesis inhibitors against the colorado potato beetle, Leptinotarsa decemlineata. Journal of insect science (Online). 2007; 7(?):1-6. doi: 10.1673/031.007.5001. [PMID: 20345285]
Monika Walter, Christopher Miles Frampton, Kirsty Sarah Helen Boyd-Wilson, Patricia Harris-Virgin, Nicholas William Waipara. Agrichemical impact on growth and survival of non-target apple phyllosphere microorganisms. Canadian journal of microbiology. 2007 Jan; 53(1):45-55. doi: 10.1139/w06-093. [PMID: 17496949]
Lee Willoughby, Henry Chung, Chris Lumb, Charles Robin, Philip Batterham, Phillip J Daborn. A comparison of Drosophila melanogaster detoxification gene induction responses for six insecticides, caffeine and phenobarbital. Insect biochemistry and molecular biology. 2006 Dec; 36(12):934-42. doi: 10.1016/j.ibmb.2006.09.004. [PMID: 17098168]
Cristina S Bastos, Raul P de Almeida, Fábio A Suinaga. Selectivity of pesticides used on cotton (Gossypium hirsutum) to Trichogramma pretiosum reared on two laboratory-reared hosts. Pest management science. 2006 Jan; 62(1):91-8. doi: 10.1002/ps.1140. [PMID: 16308868]
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