Isobutyric acid (BioDeep_00000002863)

 

Secondary id: BioDeep_00000405471, BioDeep_00000628670, BioDeep_00000868797

natural product human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite BioNovoGene_Lab2019 Volatile Flavor Compounds


代谢物信息卡片


Isobutyric acid, sodium salt, 14C-labeled

化学式: C4H8O2 (88.0524268)
中文名称: 异丁酸
谱图信息: 最多检出来源 Homo sapiens(blood) 0.27%

Reviewed

Last reviewed on 2024-09-14.

Cite this Page

Isobutyric acid. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/isobutyric_acid (retrieved 2024-11-22) (BioDeep RN: BioDeep_00000002863). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: CC(C(=O)O)C
InChI: InChI=1S/C4H8O2/c1-3(2)4(5)6/h3H,1-2H3,(H,5,6)

描述信息

Isobutyric acid is a carboxylic or short chain fatty acid with characteristic sweat-like smell. Small amount of isobutyrate is generated via microbial (gut) metabolism. Small amounts may also be found in certain foods or fermented beverages. There is anosmia (genetic inability to smell) for the odor of isobutyric acid with a frequency of about 2.5\\%. (OMIM 207000). Isobutyric acid is slightly soluble in water but much more soluble in ethanol, ether and organic solvents. Isobutyric acid can affect people if breathed in and may be absorbed through the skin. Contact can irritate and burn the skin and eyes. Breathing Isobutyric acid can irritate the nose, throat and lungs causing coughing, wheezing and/or shortness of breath.
Present in apple, morello cherry, guava fruit, wine grapes, pineapple, crispbread, other breads, cheeses, wines, scallop and several essential oils, e.g. Roman chamomile. Acid and simple esters used as flavouring agents
KEIO_ID I012

同义名列表

55 个代谢物同义名

Isobutyric acid, sodium salt, 14C-labeled; Isobutyric acid, sodium salt, 11C-labeled; Isobutyric acid, potassium salt; Isobutyric acid, hemiammoniate; Isobutyric acid, ammonium salt; Isobutyric acid, calcium salt; Isobutyric acid, sodium salt; Isobutyric acid, nickel salt; alpha-Methylpropanoic acid; alpha-Methylpropionic acid; 2-METHYL-propionIC ACID; 2,2-Dimethylacetic acid; 2-methyl-propanoic acid; a-Methylpropanoic acid; alpha-Methylpropionate; Α-methylpropanoic acid; a-Methylpropionic acid; 2-Methylpropanoic acid; Α-methylpropionic acid; alpha-Methylpropanoate; 2-Methylpropionic acid; 2-Methylpropionsaeure; alpha-Isobutyric acid; Ammonium isobutyrate; 2-Methpropanoic acid; Isopropylformic acid; 2,2-Dimethylacetate; Dimethylacetic acid; 2-METHYL-propionate; a-Methylpropionate; Α-methylpropanoate; 2-Methylpropanoate; Α-methylpropionate; a-Methylpropanoate; 2-Methylpropionate; Sodium isobutyrate; a-Isobutyric acid; Α-isobutyric acid; alpha-Isobutyrate; Isopropylformate; Isobutanoic acid; Iso-butyric acid; ISOBUTYRIC ACID; Dimethylacetate; Isobuttersaeure; I-butyric acid; Α-isobutyrate; a-Isobutyrate; Iso-C3H7COOH; Iso-butyrate; Isobutanoate; Isobutyrate; I-butyrate; Isobutyric acid; 2-Methylpropanoate



数据库引用编号

29 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

116 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yiming Ni, Liangyin Cai, Xiaojun Gou, Wenjie Li, Mingmei Zhou, Ying Huang. Therapeutic effect of Sanhua decoction on rats with middle cerebral artery occlusion and the associated changes in gut microbiota and short-chain fatty acids. PloS one. 2024; 19(2):e0298148. doi: 10.1371/journal.pone.0298148. [PMID: 38363776]
  • Xiao-Na Huang, Chen-Yang Zhu, Yu-Zhen Li, Chun-Hui Jin. [Weidiao-3 Mixture Improves the Clinical Efficacy of Immunotherapy for Advanced Gastric Cancer by Regulating Intestinal Flora]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. 2023 Aug; 45(4):581-590. doi: 10.3881/j.issn.1000-503x.15496. [PMID: 37654138]
  • Xiaoying Liu, Chenxu Wang, Yumeng Wang, Chaohui Wang, Xi Sun, Yufei Zhu, Xiaojun Yang, Lixin Zhang, Yanli Liu. Age-associated changes in the growth development of abdominal fat and their correlations with cecal gut microbiota in broiler chickens. Poultry science. 2023 Jun; 102(9):102900. doi: 10.1016/j.psj.2023.102900. [PMID: 37406441]
  • Kiana Ashley West, Chidimma Kanu, Tanya Maric, Julie Anne Kathryn McDonald, Jeremy K Nicholson, Jia V Li, Mark R Johnson, Elaine Holmes, Makrina D Savvidou. Longitudinal metabolic and gut bacterial profiling of pregnant women with previous bariatric surgery. Gut. 2020 08; 69(8):1452-1459. doi: 10.1136/gutjnl-2019-319620. [PMID: 31964751]
  • N Urrutia, R Bomberger, C Matamoros, K J Harvatine. Effect of dietary supplementation of sodium acetate and calcium butyrate on milk fat synthesis in lactating dairy cows. Journal of dairy science. 2019 Jun; 102(6):5172-5181. doi: 10.3168/jds.2018-16024. [PMID: 30981489]
  • Ariel Bier, Tzipi Braun, Rawan Khasbab, Ayelet Di Segni, Ehud Grossman, Yael Haberman, Avshalom Leibowitz. A High Salt Diet Modulates the Gut Microbiota and Short Chain Fatty Acids Production in a Salt-Sensitive Hypertension Rat Model. Nutrients. 2018 Aug; 10(9):. doi: 10.3390/nu10091154. [PMID: 30142973]
  • T Ya Vakhitov, N Chalisova, S I Sitkin. EFFECT OF CARBOXYLIC ACIDS OF GUT MICROBIAL ORIGIN ON HOST CELL PROLIFERATION IN ORGANOTYPIC TISSUE CULTURES. Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology. 2016 Jul; 12(12):73-82. doi: . [PMID: 29889427]
  • George A Schaible, Gary A Strobel, Morgan Tess Mends, Brad Geary, Joe Sears. Characterization of an Endophytic Gloeosporium sp. and Its Novel Bioactivity with 'Synergistans'. Microbial ecology. 2015 Jul; 70(1):41-50. doi: 10.1007/s00248-014-0542-y. [PMID: 25501886]
  • Greta Jakobsdottir, Jens Holst Bjerregaard, Hanne Skovbjerg, Margareta Nyman. Fasting serum concentration of short-chain fatty acids in subjects with microscopic colitis and celiac disease: no difference compared with controls, but between genders. Scandinavian journal of gastroenterology. 2013 Jun; 48(6):696-701. doi: 10.3109/00365521.2013.786128. [PMID: 23600961]
  • Ayshamgul Hasim, Hong Ma, Batur Mamtimin, Abulizi Abudula, Madiniyet Niyaz, Li-Wei Zhang, Juret Anwer, Ilyar Sheyhidin. Revealing the metabonomic variation of EC using ¹H-NMR spectroscopy and its association with the clinicopathological characteristics. Molecular biology reports. 2012 Sep; 39(9):8955-64. doi: 10.1007/s11033-012-1764-z. [PMID: 22736106]
  • Emiko Kokushi, Seiichi Uno, Tomotaka Harada, Jiro Koyama. ¹H NMR-based metabolomics approach to assess toxicity of bunker a heavy oil to freshwater carp, Cyprinus carpio. Environmental toxicology. 2012 Jul; 27(7):404-14. doi: 10.1002/tox.20653. [PMID: 20882592]
  • Suwen Qi, Zhiguang Tu, Xin Ouyang, Linxian Wang, Wujian Peng, Anji Cai, Yong Dai. Comparison of the metabolic profiling of hepatitis B virus-infected cirrhosis and alcoholic cirrhosis patients by using (1) H NMR-based metabonomics. Hepatology research : the official journal of the Japan Society of Hepatology. 2012 Jul; 42(7):677-85. doi: 10.1111/j.1872-034x.2011.00964.x. [PMID: 22404306]
  • Yosuke Hanai, Ken Shimono, Hiroaki Oka, Yoshinobu Baba, Kunio Yamazaki, Gary K Beauchamp. Analysis of volatile organic compounds released from human lung cancer cells and from the urine of tumor-bearing mice. Cancer cell international. 2012 Feb; 12(1):7. doi: 10.1186/1475-2867-12-7. [PMID: 22364569]
  • K R Kerr, B M Vester Boler, C L Morris, K J Liu, K S Swanson. Apparent total tract energy and macronutrient digestibility and fecal fermentative end-product concentrations of domestic cats fed extruded, raw beef-based, and cooked beef-based diets. Journal of animal science. 2012 Feb; 90(2):515-22. doi: 10.2527/jas.2010-3266. [PMID: 22003235]
  • Raquel Conde-Álvarez, Vilma Arce-Gorvel, Maite Iriarte, Mateja Manček-Keber, Elías Barquero-Calvo, Leyre Palacios-Chaves, Carlos Chacón-Díaz, Esteban Chaves-Olarte, Anna Martirosyan, Kristine von Bargen, María-Jesús Grilló, Roman Jerala, Klaus Brandenburg, Enrique Llobet, José A Bengoechea, Edgardo Moreno, Ignacio Moriyón, Jean-Pierre Gorvel. The lipopolysaccharide core of Brucella abortus acts as a shield against innate immunity recognition. PLoS pathogens. 2012; 8(5):e1002675. doi: 10.1371/journal.ppat.1002675. [PMID: 22589715]
  • Karen K Y Lam, Xingji Zheng, Roberto Forestieri, Aruna D Balgi, Matt Nodwell, Sarah Vollett, Hilary J Anderson, Raymond J Andersen, Yossef Av-Gay, Michel Roberge. Nitazoxanide stimulates autophagy and inhibits mTORC1 signaling and intracellular proliferation of Mycobacterium tuberculosis. PLoS pathogens. 2012; 8(5):e1002691. doi: 10.1371/journal.ppat.1002691. [PMID: 22589723]
  • K Okada, H Kanoh, K Mohri. Effects of clofibric acid on the biliary excretion of benoxaprofen glucuronide and taurine conjugate in rats. Die Pharmazie. 2011 Oct; 66(10):777-83. doi: . [PMID: 22026160]
  • Kunju Sathishkumar, Rebekah Elkins, Vijayakumar Chinnathambi, Haijun Gao, Gary D V Hankins, Chandra Yallampalli. Prenatal testosterone-induced fetal growth restriction is associated with down-regulation of rat placental amino acid transport. Reproductive biology and endocrinology : RB&E. 2011 Aug; 9(?):110. doi: 10.1186/1477-7827-9-110. [PMID: 21812961]
  • Max C Liebau, Katja Höpker, Roman U Müller, Ingolf Schmedding, Sibylle Zank, Benjamin Schairer, Francesca Fabretti, Martin Höhne, Malte P Bartram, Claudia Dafinger, Matthias Hackl, Volker Burst, Sandra Habbig, Hanswalter Zentgraf, Andree Blaukat, Gerd Walz, Thomas Benzing, Bernhard Schermer. Nephrocystin-4 regulates Pyk2-induced tyrosine phosphorylation of nephrocystin-1 to control targeting to monocilia. The Journal of biological chemistry. 2011 Apr; 286(16):14237-45. doi: 10.1074/jbc.m110.165464. [PMID: 21357692]
  • Ramesh B Potu, Amer A AbuGhazaleh, Darcie Hastings, Karen Jones, Salam A Ibrahim. The effect of lipid supplements on ruminal bacteria in continuous culture fermenters varies with the fatty acid composition. Journal of microbiology (Seoul, Korea). 2011 Apr; 49(2):216-23. doi: 10.1007/s12275-011-0365-1. [PMID: 21538241]
  • D E Cross, R M McDevitt, T Acamovic. Herbs, thyme essential oil and condensed tannin extracts as dietary supplements for broilers, and their effects on performance, digestibility, volatile fatty acids and organoleptic properties. British poultry science. 2011 Apr; 52(2):227-37. doi: 10.1080/00071668.2011.559454. [PMID: 21491246]
  • Ronan Corcuff, Julien Mercier, Russell Tweddell, Joseph Arul. Effect of water activity on the production of volatile organic compounds by Muscodor albus and their effect on three pathogens in stored potato. Fungal biology. 2011 Mar; 115(3):220-7. doi: 10.1016/j.funbio.2010.12.005. [PMID: 21354528]
  • Xiao Wu, Sébastien Monchy, Safiyh Taghavi, Wei Zhu, Juan Ramos, Daniel van der Lelie. Comparative genomics and functional analysis of niche-specific adaptation in Pseudomonas putida. FEMS microbiology reviews. 2011 Mar; 35(2):299-323. doi: 10.1111/j.1574-6976.2010.00249.x. [PMID: 20796030]
  • Amrita Pati, Sabine Gronow, Ahmet Zeytun, Alla Lapidus, Matt Nolan, Nancy Hammon, Shweta Deshpande, Jan-Fang Cheng, Roxane Tapia, Cliff Han, Lynne Goodwin, Sam Pitluck, Konstantinos Liolios, Ioanna Pagani, Natalia Ivanova, Konstantinos Mavromatis, Amy Chen, Krishna Palaniappan, Miriam Land, Loren Hauser, Yun-Juan Chang, Cynthia D Jeffries, John C Detter, Evelyne Brambilla, Manfred Rohde, Markus Göker, Tanja Woyke, James Bristow, Jonathan A Eisen, Victor Markowitz, Philip Hugenholtz, Nikos C Kyrpides, Hans-Peter Klenk, Susan Lucas. Complete genome sequence of Bacteroides helcogenes type strain (P 36-108). Standards in genomic sciences. 2011 Feb; 4(1):45-53. doi: 10.4056/sigs.1513795. [PMID: 21475586]
  • Shiyuan Hu, Huajun Zheng, Yang Gu, Jingbo Zhao, Weiwen Zhang, Yunliu Yang, Shengyue Wang, Guoping Zhao, Sheng Yang, Weihong Jiang. Comparative genomic and transcriptomic analysis revealed genetic characteristics related to solvent formation and xylose utilization in Clostridium acetobutylicum EA 2018. BMC genomics. 2011 Feb; 12(?):93. doi: 10.1186/1471-2164-12-93. [PMID: 21284892]
  • Mari Aidemark, Henrik Tjellström, Anna Stina Sandelius, Henrik Stålbrand, Erik Andreasson, Allan G Rasmusson, Susanne Widell. Trichoderma viride cellulase induces resistance to the antibiotic pore-forming peptide alamethicin associated with changes in the plasma membrane lipid composition of tobacco BY-2 cells. BMC plant biology. 2010 Dec; 10(?):274. doi: 10.1186/1471-2229-10-274. [PMID: 21156059]
  • Bibi Rafeiza Khan, Bethany K Zolman. pex5 Mutants that differentially disrupt PTS1 and PTS2 peroxisomal matrix protein import in Arabidopsis. Plant physiology. 2010 Dec; 154(4):1602-15. doi: 10.1104/pp.110.162479. [PMID: 20974890]
  • V A Corriher, G M Hill, J K Bernard, T C Jenkins, J W West, B G Mullinix. Pigeon peas as a supplement for lactating dairy cows fed corn silage-based diets. Journal of dairy science. 2010 Nov; 93(11):5309-17. doi: 10.3168/jds.2010-3182. [PMID: 20965347]
  • Hasim Ayshamgul, Mamtimin Batur, Sheyhidin Ilyar. [1H-MRS metabonomic analysis of plasma samples of esophageal cancer patients based on different pattern recognition]. Zhonghua zhong liu za zhi [Chinese journal of oncology]. 2010 Sep; 32(9):681-4. doi: . [PMID: 21122383]
  • K A Barry, B J Wojcicki, I S Middelbos, B M Vester, K S Swanson, G C Fahey. Dietary cellulose, fructooligosaccharides, and pectin modify fecal protein catabolites and microbial populations in adult cats. Journal of animal science. 2010 Sep; 88(9):2978-87. doi: 10.2527/jas.2009-2464. [PMID: 20495116]
  • Robin F Benus, Hermie J Harmsen, Gjalt W Welling, Rob Spanjersberg, Jan G Zijlstra, John E Degener, Tjip S van der Werf. Impact of digestive and oropharyngeal decontamination on the intestinal microbiota in ICU patients. Intensive care medicine. 2010 Aug; 36(8):1394-402. doi: 10.1007/s00134-010-1826-4. [PMID: 20232045]
  • Tomás Rezanka, Ales Prell, Jaroslav Spízek, Karel Sigler. Pilot-plant cultivation of Streptomyces griseus producing homologues of nonactin by precursor-directed biosynthesis and their identification by LC/MS-ESI. The Journal of antibiotics. 2010 Aug; 63(8):524-9. doi: 10.1038/ja.2010.93. [PMID: 20664602]
  • Federico E Rey, Jeremiah J Faith, James Bain, Michael J Muehlbauer, Robert D Stevens, Christopher B Newgard, Jeffrey I Gordon. Dissecting the in vivo metabolic potential of two human gut acetogens. The Journal of biological chemistry. 2010 Jul; 285(29):22082-90. doi: 10.1074/jbc.m110.117713. [PMID: 20444704]
  • Ge-Fei Hao, Guang-Fu Yang. The role of Phe82 and Phe351 in auxin-induced substrate perception by TIR1 ubiquitin ligase: a novel insight from molecular dynamics simulations. PloS one. 2010 May; 5(5):e10742. doi: 10.1371/journal.pone.0010742. [PMID: 20505777]
  • Susan C Connor, Michael K Hansen, Adam Corner, Randall F Smith, Terence E Ryan. Integration of metabolomics and transcriptomics data to aid biomarker discovery in type 2 diabetes. Molecular bioSystems. 2010 May; 6(5):909-21. doi: 10.1039/b914182k. [PMID: 20567778]
  • Anthony Schilmiller, Feng Shi, Jeongwoon Kim, Amanda L Charbonneau, Daniel Holmes, A Daniel Jones, Robert L Last. Mass spectrometry screening reveals widespread diversity in trichome specialized metabolites of tomato chromosomal substitution lines. The Plant journal : for cell and molecular biology. 2010 May; 62(3):391-403. doi: 10.1111/j.1365-313x.2010.04154.x. [PMID: 20113441]
  • Catalina March, Verónica Regueiro, Enrique Llobet, David Moranta, Pau Morey, Junkal Garmendia, José A Bengoechea. Dissection of host cell signal transduction during Acinetobacter baumannii-triggered inflammatory response. PloS one. 2010 Apr; 5(4):e10033. doi: 10.1371/journal.pone.0010033. [PMID: 20383325]
  • P E Urriola, H H Stein. Effects of distillers dried grains with solubles on amino acid, energy, and fiber digestibility and on hindgut fermentation of dietary fiber in a corn-soybean meal diet fed to growing pigs. Journal of animal science. 2010 Apr; 88(4):1454-62. doi: 10.2527/jas.2009-2162. [PMID: 20023135]
  • E Molina-Alcaide, A I Martín-García, A Moumen, M D Carro. Ruminal fermentation, microbial growth and amino acid flow in single-flow continuous culture fermenters fed a diet containing olive leaves. Journal of animal physiology and animal nutrition. 2010 Apr; 94(2):227-36. doi: 10.1111/j.1439-0396.2008.00905.x. [PMID: 19175451]
  • Hiroshi Sato, Yumiko Shiogama. Acetone and isopropanol in ruminal fluid and feces of lactating dairy cows. The Journal of veterinary medical science. 2010 Mar; 72(3):297-300. doi: 10.1292/jvms.09-0227. [PMID: 19959888]
  • J Cameron Thrash, Jarrod Pollock, Tamas Torok, John D Coates. Description of the novel perchlorate-reducing bacteria Dechlorobacter hydrogenophilus gen. nov., sp. nov.and Propionivibrio militaris, sp. nov. Applied microbiology and biotechnology. 2010 Mar; 86(1):335-43. doi: 10.1007/s00253-009-2336-6. [PMID: 19921177]
  • M L May, M J Quinn, C D Reinhardt, L Murray, M L Gibson, K K Karges, J S Drouillard. Effects of dry-rolled or steam-flaked corn finishing diets with or without twenty-five percent dried distillers grains on ruminal fermentation and apparent total tract digestion. Journal of animal science. 2009 Nov; 87(11):3630-8. doi: 10.2527/jas.2008-0857. [PMID: 19648506]
  • K A Barry, D C Hernot, I S Middelbos, C Francis, B Dunsford, K S Swanson, G C Fahey. Low-level fructan supplementation of dogs enhances nutrient digestion and modifies stool metabolite concentrations, but does not alter fecal microbiota populations. Journal of animal science. 2009 Oct; 87(10):3244-52. doi: 10.2527/jas.2008-1659. [PMID: 19574565]
  • Ritu Lal, Juthamas Sukbuntherng, Ezra H L Tai, Shubhra Upadhyay, Fenmei Yao, Mark S Warren, Wendy Luo, Lin Bu, Son Nguyen, Jeanelle Zamora, Ge Peng, Tracy Dias, Ying Bao, Maria Ludwikow, Thu Phan, Randall A Scheuerman, Hui Yan, Mark Gao, Quincey Q Wu, Thamil Annamalai, Stephen P Raillard, Kerry Koller, Mark A Gallop, Kenneth C Cundy. Arbaclofen placarbil, a novel R-baclofen prodrug: improved absorption, distribution, metabolism, and elimination properties compared with R-baclofen. The Journal of pharmacology and experimental therapeutics. 2009 Sep; 330(3):911-21. doi: 10.1124/jpet.108.149773. [PMID: 19502531]
  • M J Spiehs, V H Varel. Nutrient excretion and odorant production in manure from cattle fed corn wet distillers grains with solubles. Journal of animal science. 2009 Sep; 87(9):2977-84. doi: 10.2527/jas.2008-1584. [PMID: 19502500]
  • Donovan P German. Do herbivorous minnows have 'plug-flow reactor' guts? Evidence from digestive enzyme activities, gastrointestinal fermentation, and luminal nutrient concentrations. Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology. 2009 Aug; 179(6):759-71. doi: 10.1007/s00360-009-0359-z. [PMID: 19363616]
  • I Ntaikou, C Kourmentza, E C Koutrouli, K Stamatelatou, A Zampraka, M Kornaros, G Lyberatos. Exploitation of olive oil mill wastewater for combined biohydrogen and biopolymers production. Bioresource technology. 2009 Aug; 100(15):3724-30. doi: 10.1016/j.biortech.2008.12.001. [PMID: 19138844]
  • Hasim Ayxiam, Hong Ma, Sheyhidin Ilyar, Li-Wei Zhang, Abudula Ablizi, Mamtimin Batur, Xiao-Mei Lu. [Metabonomic variation of esophageal cancer within different ethnic groups in Xinjiang, China]. Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine]. 2009 Jul; 43(7):591-6. doi: . [PMID: 19954070]
  • Hanne Christine Bertram, Bent Ole Petersen, Jens Ø Duus, Mogens Larsen, Birgitte-Marie L Raun, Niels Bastian Kristensen. Proton nuclear magnetic resonance spectroscopy based investigation on propylene glycol toxicosis in a Holstein cow. Acta veterinaria Scandinavica. 2009 Jun; 51(?):25. doi: 10.1186/1751-0147-51-25. [PMID: 19523238]
  • Cláudia Gomes Silva, Joaquim Luís Faria. Anatase vs. rutile efficiency on the photocatalytic degradation of clofibric acid under near UV to visible irradiation. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology. 2009 May; 8(5):705-11. doi: 10.1039/b817364h. [PMID: 19424546]
  • F Bovera, S D'Urso, C Di Meo, R Tudisco, A Nizza. A model to assess the use of caecal and faecal inocula to study fermentability of nutrients in rabbit. Journal of animal physiology and animal nutrition. 2009 Apr; 93(2):147-56. doi: 10.1111/j.1439-0396.2007.00795.x. [PMID: 19320927]
  • Qiang Liu, Cong Wang, YingXiang Huang, KuanHu Dong, WenZu Yang, Hao Wang. Effects of isobutyrate on rumen fermentation, urinary excretion of purine derivatives and digestibility in steers. Archives of animal nutrition. 2008 Oct; 62(5):377-88. doi: 10.1080/17450390802327761. [PMID: 18942585]
  • B S Khyshiktuev, T M Karavaeva, E V Fal'ko. [Variability of quantitative changes in short-chain fatty acids in serum and epidermis in psoriasis]. Klinicheskaia laboratornaia diagnostika. 2008 Aug; ?(8):22-4. doi: NULL. [PMID: 18810829]
  • U Nilsson, M Johansson, A Nilsson, I Björck, M Nyman. Dietary supplementation with beta-glucan enriched oat bran increases faecal concentration of carboxylic acids in healthy subjects. European journal of clinical nutrition. 2008 Aug; 62(8):978-84. doi: 10.1038/sj.ejcn.1602816. [PMID: 17522598]
  • Christina Keese, Ulrich Meyer, Jürgen Rehage, Joachim Spilke, Jeannette Boguhn, Gerhard Breves, Sven Dänicke. Ruminal fermentation patterns and parameters of the acid base metabolism in the urine as influenced by the proportion of concentrate in the ration of dairy cows with and without Fusarium toxin-contaminated triticale. Archives of animal nutrition. 2008 Aug; 62(4):287-302. doi: 10.1080/17450390802066443. [PMID: 18763623]
  • Doris M Jacobs, Nancy Deltimple, Ewoud van Velzen, Ferdi A van Dorsten, Max Bingham, Elaine E Vaughan, John van Duynhoven. (1)H NMR metabolite profiling of feces as a tool to assess the impact of nutrition on the human microbiome. NMR in biomedicine. 2008 Jul; 21(6):615-26. doi: 10.1002/nbm.1233. [PMID: 18085514]
  • Gary A Strobel, Shanney Spang, Katreena Kluck, W M Hess, Joe Sears, Tom Livinghouse. Synergism among volatile organic compounds resulting in increased antibiosis in Oidium sp. FEMS microbiology letters. 2008 Jun; 283(2):140-5. doi: 10.1111/j.1574-6968.2008.01137.x. [PMID: 18422630]
  • A Mahran, M Tenuta, M L Hanson, F Daayf. Mortality of Pratylenchus penetrans by Volatile Fatty Acids from Liquid Hog Manure. Journal of nematology. 2008 Jun; 40(2):119-26. doi: ". [PMID: 19259528]
  • C M Westermann, L Dorland, D M Votion, M G M de Sain-van der Velden, I D Wijnberg, R J A Wanders, W G M Spliet, N Testerink, R Berger, J P N Ruiter, J H van der Kolk. Acquired multiple Acyl-CoA dehydrogenase deficiency in 10 horses with atypical myopathy. Neuromuscular disorders : NMD. 2008 May; 18(5):355-64. doi: 10.1016/j.nmd.2008.02.007. [PMID: 18406615]
  • Jyunichi Kawata, Munekazu Kameda, Mitsuo Miyazawa. Cyclooxygenase-2 inhibitory effects and composition of the volatile oil from the dried roots of Lithospermum erythrorhizon. Journal of natural medicines. 2008 Apr; 62(2):239-43. doi: 10.1007/s11418-007-0221-0. [PMID: 18404332]
  • Duangjit Kanistanon, Adeline M Hajjar, Mark R Pelletier, Larry A Gallagher, Thomas Kalhorn, Scott A Shaffer, David R Goodlett, Laurence Rohmer, Mitchell J Brittnacher, Shawn J Skerrett, Robert K Ernst. A Francisella mutant in lipid A carbohydrate modification elicits protective immunity. PLoS pathogens. 2008 Feb; 4(2):e24. doi: 10.1371/journal.ppat.0040024. [PMID: 18266468]
  • Hsiao-Ling Chen, Han-Chung Cheng, Wen-Tsu Wu, Yann-Jiu Liu, Su-Yuan Liu. Supplementation of konjac glucomannan into a low-fiber Chinese diet promoted bowel movement and improved colonic ecology in constipated adults: a placebo-controlled, diet-controlled trial. Journal of the American College of Nutrition. 2008 Feb; 27(1):102-8. doi: 10.1080/07315724.2008.10719681. [PMID: 18460488]
  • Francois-Pierre J Martin, Yulan Wang, Norbert Sprenger, Ivan K S Yap, Torbjörn Lundstedt, Per Lek, Serge Rezzi, Ziad Ramadan, Peter van Bladeren, Laurent B Fay, Sunil Kochhar, John C Lindon, Elaine Holmes, Jeremy K Nicholson. Probiotic modulation of symbiotic gut microbial-host metabolic interactions in a humanized microbiome mouse model. Molecular systems biology. 2008; 4(?):157. doi: 10.1038/msb4100190. [PMID: 18197175]
  • Francois-Pierre J Martin, Yulan Wang, Norbert Sprenger, Ivan K S Yap, Serge Rezzi, Ziad Ramadan, Emma Peré-Trepat, Florence Rochat, Christine Cherbut, Peter van Bladeren, Laurent B Fay, Sunil Kochhar, John C Lindon, Elaine Holmes, Jeremy K Nicholson. Top-down systems biology integration of conditional prebiotic modulated transgenomic interactions in a humanized microbiome mouse model. Molecular systems biology. 2008; 4(?):205. doi: 10.1038/msb.2008.40. [PMID: 18628745]
  • Jae Kwak, Alan Willse, Koichi Matsumura, Maryanne Curran Opiekun, Weiguang Yi, George Preti, Kunio Yamazaki, Gary K Beauchamp. Genetically-based olfactory signatures persist despite dietary variation. PloS one. 2008; 3(10):e3591. doi: 10.1371/journal.pone.0003591. [PMID: 18974891]
  • J K Htoo, B A Araiza, W C Sauer, M Rademacher, Y Zhang, M Cervantes, R T Zijlstra. Effect of dietary protein content on ileal amino acid digestibility, growth performance, and formation of microbial metabolites in ileal and cecal digesta of early-weaned pigs. Journal of animal science. 2007 Dec; 85(12):3303-12. doi: 10.2527/jas.2007-0105. [PMID: 17785591]
  • Voravee P Hoven, Mayuree Srinanthakul, Yasuhiko Iwasaki, Ryoko Iwata, Suda Kiatkamjornwong. Polymer brushes in nanopores surrounded by silicon-supported tris(trimethylsiloxy)silyl monolayers. Journal of colloid and interface science. 2007 Oct; 314(2):446-59. doi: 10.1016/j.jcis.2007.05.088. [PMID: 17662300]
  • Bo Tjellström, Lars Stenhammar, Lotta Högberg, Karin Fälth-Magnusson, Karl-Eric Magnusson, Tore Midtvedt, Tommy Sundqvist, Richard Houlston, Sanjay Popat, Elisabeth Norin. Gut microflora associated characteristics in first-degree relatives of children with celiac disease. Scandinavian journal of gastroenterology. 2007 Oct; 42(10):1204-8. doi: 10.1080/00365520701320687. [PMID: 17852880]
  • Mahiran Basri, Raja Noor Zaliha Raja Abd Rahman, Afshin Ebrahimpour, Abu Bakar Salleh, Erin Ryantin Gunawan, Mohd Basyaruddin Abd Rahman. Comparison of estimation capabilities of response surface methodology (RSM) with artificial neural network (ANN) in lipase-catalyzed synthesis of palm-based wax ester. BMC biotechnology. 2007 Aug; 7(?):53. doi: 10.1186/1472-6750-7-53. [PMID: 17760990]
  • Kerry A Lucas, Jessica R Filley, Jeremy M Erb, Eric R Graybill, John W Hawes. Peroxisomal metabolism of propionic acid and isobutyric acid in plants. The Journal of biological chemistry. 2007 Aug; 282(34):24980-9. doi: 10.1074/jbc.m701028200. [PMID: 17580301]
  • Lei He, Xi Li, He-Sheng Luo, Han Rong, Jia Cai. Possible mechanism for the regulation of glucose on proliferation, inhibition and apoptosis of colon cancer cells induced by sodium butyrate. World journal of gastroenterology. 2007 Aug; 13(29):4015-8. doi: 10.3748/wjg.v13.i29.4015. [PMID: 17663521]
  • Gary A Strobel, Katreena Kluck, Wilford M Hess, Joe Sears, David Ezra, Percy N Vargas. Muscodor albus E-6, an endophyte of Guazuma ulmifolia making volatile antibiotics: isolation, characterization and experimental establishment in the host plant. Microbiology (Reading, England). 2007 Aug; 153(Pt 8):2613-2620. doi: 10.1099/mic.0.2007/008912-0. [PMID: 17660425]
  • Edward R Farnworth, Yvan P Chouinard, Helene Jacques, Sudha Venkatramanan, Akier A Maf, Sabrina Defnoun, Peter J H Jones. The effect of drinking milk containing conjugated linoleic acid on fecal microbiological profile, enzymatic activity, and fecal characteristics in humans. Nutrition journal. 2007 Jul; 6(?):15. doi: 10.1186/1475-2891-6-15. [PMID: 17620127]
  • Christian Barmeyer, Jeff Huaqing Ye, Shafik Sidani, John Geibel, Henry J Binder, Vazhaikkurichi M Rajendran. Characteristics of rat downregulated in adenoma (rDRA) expressed in HEK 293 cells. Pflugers Archiv : European journal of physiology. 2007 Jun; 454(3):441-50. doi: 10.1007/s00424-007-0213-7. [PMID: 17492310]
  • K D Dunkley, C S Dunkley, N L Njongmeta, T R Callaway, M E Hume, L F Kubena, D J Nisbet, S C Ricke. Comparison of in vitro fermentation and molecular microbial profiles of high-fiber feed substrates incubated with chicken cecal inocula. Poultry science. 2007 May; 86(5):801-10. doi: 10.1093/ps/86.5.801. [PMID: 17435012]
  • C Wyss. Fatty acids synthesized by oral treponemes in chemically defined media. FEMS microbiology letters. 2007 Apr; 269(1):70-6. doi: 10.1111/j.1574-6968.2006.00609.x. [PMID: 17229060]
  • Shong Ji Piao, Takamitsu Tsukahara, Mitsugi Itoh, Akira Shiga, Yoshikazu Adachi, Kazunari Ushida. The organic acid profiles in the feces of pigs at Brachyspira hyodysenteriae- or B. pilosicoli-positive farms. The Journal of veterinary medical science. 2007 Apr; 69(4):425-8. doi: 10.1292/jvms.69.425. [PMID: 17485934]
  • Katie M Queenan, Maria L Stewart, Kristen N Smith, William Thomas, R Gary Fulcher, Joanne L Slavin. Concentrated oat beta-glucan, a fermentable fiber, lowers serum cholesterol in hypercholesterolemic adults in a randomized controlled trial. Nutrition journal. 2007 Mar; 6(?):6. doi: 10.1186/1475-2891-6-6. [PMID: 17386092]
  • Guohua Zhao, Jing-Fu Liu, Margareta Nyman, Jan Ake Jönsson. Determination of short-chain fatty acids in serum by hollow fiber supported liquid membrane extraction coupled with gas chromatography. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2007 Feb; 846(1-2):202-8. doi: 10.1016/j.jchromb.2006.09.027. [PMID: 17070116]
  • John R Pluske, Lucile Montagne, Fiona S Cavaney, Bruce P Mullan, David W Pethick, David J Hampson. Feeding different types of cooked white rice to piglets after weaning influences starch digestion, digesta and fermentation characteristics and the faecal shedding of beta-haemolytic Escherichia coli. The British journal of nutrition. 2007 Feb; 97(2):298-306. doi: 10.1017/s0007114507332534. [PMID: 17298698]
  • Nicoletta Beffagna, Irene Lutzu. Inhibition of catalase activity as an early response of Arabidopsis thaliana cultured cells to the phytotoxin fusicoccin. Journal of experimental botany. 2007; 58(15-16):4183-94. doi: 10.1093/jxb/erm275. [PMID: 18039736]
  • François-Pierre J Martin, Marc-Emmanuel Dumas, Yulan Wang, Cristina Legido-Quigley, Ivan K S Yap, Huiru Tang, Séverine Zirah, Gerard M Murphy, Olivier Cloarec, John C Lindon, Norbert Sprenger, Laurent B Fay, Sunil Kochhar, Peter van Bladeren, Elaine Holmes, Jeremy K Nicholson. A top-down systems biology view of microbiome-mammalian metabolic interactions in a mouse model. Molecular systems biology. 2007; 3(?):112. doi: 10.1038/msb4100153. [PMID: 17515922]
  • Mohan A Dhale, S Divakar, S Umesh Kumar, G Vijayalakshmi. Isolation and characterization of dihydromonacolin-MV from Monascus purpureus for antioxidant properties. Applied microbiology and biotechnology. 2007 Jan; 73(5):1197-202. doi: 10.1007/s00253-006-0578-0. [PMID: 17043831]
  • Guohua Zhao, Margareta Nyman, Jan Ake Jönsson. Rapid determination of short-chain fatty acids in colonic contents and faeces of humans and rats by acidified water-extraction and direct-injection gas chromatography. Biomedical chromatography : BMC. 2006 Aug; 20(8):674-82. doi: 10.1002/bmc.580. [PMID: 16206138]
  • Michael Fahrbach, Jan Kuever, Ruth Meinke, Peter Kämpfer, Juliane Hollender. Denitratisoma oestradiolicum gen. nov., sp. nov., a 17beta-oestradiol-degrading, denitrifying betaproteobacterium. International journal of systematic and evolutionary microbiology. 2006 Jul; 56(Pt 7):1547-1552. doi: 10.1099/ijs.0.63672-0. [PMID: 16825628]
  • Marina Himanen, Kyösti Latva-Kala, Merja Itävaara, Kari Hänninen. A method for measuring low-weight carboxylic acids from biosolid compost. Journal of environmental quality. 2006 Mar; 35(2):516-21. doi: 10.2134/jeq2004.0443. [PMID: 16455852]
  • Yulan Wang, Mary E Bollard, Jeremy K Nicholson, Elaine Holmes. Exploration of the direct metabolic effects of mercury II chloride on the kidney of Sprague-Dawley rats using high-resolution magic angle spinning 1H NMR spectroscopy of intact tissue and pattern recognition. Journal of pharmaceutical and biomedical analysis. 2006 Feb; 40(2):375-81. doi: 10.1016/j.jpba.2005.07.019. [PMID: 16146678]
  • Zhen-Hu Hu, Han-Qing Yu. Anaerobic digestion of cattail by rumen cultures. Waste management (New York, N.Y.). 2006; 26(11):1222-8. doi: 10.1016/j.wasman.2005.08.003. [PMID: 16198552]
  • Anna Stojakowska, Bogdan Kedzia, Wanda Kisiel. Antimicrobial activity of 10-isobutyryloxy-8,9-epoxythymol isobutyrate. Fitoterapia. 2005 Dec; 76(7-8):687-90. doi: 10.1016/j.fitote.2005.05.003. [PMID: 16242268]
  • Anne-Judith Waligora-Dupriet, Annabelle Dugay, Nicolas Auzeil, Michel Huerre, Marie-José Butel. Evidence for clostridial implication in necrotizing enterocolitis through bacterial fermentation in a gnotobiotic quail model. Pediatric research. 2005 Oct; 58(4):629-35. doi: 10.1203/01.pdr.0000180538.13142.84. [PMID: 16189185]
  • Asmaa El Hamidi, Alina Tirsoaga, Alexey Novikov, Ahmed Hussein, Martine Caroff. Microextraction of bacterial lipid A: easy and rapid method for mass spectrometric characterization. Journal of lipid research. 2005 Aug; 46(8):1773-8. doi: 10.1194/jlr.d500014-jlr200. [PMID: 15930524]
  • Muriel Vellutini, Nicolas Baldovini, Dominique de Rocca Serra, Félix Tomi, Joseph Casanova. Beta-cyclolavandulyl and beta-isocyclolavandulyl esters from Peucedanum paniculatum L., an endemic species to Corsica. Phytochemistry. 2005 Aug; 66(16):1956-62. doi: 10.1016/j.phytochem.2005.07.001. [PMID: 16099484]
  • Fadwa E L Hanbali, Mohamed Akssira, Aicha Ezoubeiri, Chems Eddoha A Gadhi, Fouad Mellouki, Ahmed Benherraf, Amparo M Blazquez, Herminio Boira. Chemical composition and antibacterial activity of essential oil of Pulicaria odora L. Journal of ethnopharmacology. 2005 Jul; 99(3):399-401. doi: 10.1016/j.jep.2005.01.012. [PMID: 15896934]
  • Eileen Looby, Aideen Long, Dermot Kelleher, Yuri Volkov. Bile acid deoxycholate induces differential subcellular localisation of the PKC isoenzymes beta 1, epsilon and delta in colonic epithelial cells in a sodium butyrate insensitive manner. International journal of cancer. 2005 May; 114(6):887-95. doi: 10.1002/ijc.20803. [PMID: 15645414]
  • M Consuelo Díaz-Maroto, Rémi Schneider, Raymond Baumes. Formation pathways of ethyl esters of branched short-chain fatty acids during wine aging. Journal of agricultural and food chemistry. 2005 May; 53(9):3503-9. doi: 10.1021/jf048157o. [PMID: 15853394]
  • Thomas Hiesberger, Xinli Shao, Eric Gourley, Andreas Reimann, Marco Pontoglio, Peter Igarashi. Role of the hepatocyte nuclear factor-1beta (HNF-1beta) C-terminal domain in Pkhd1 (ARPKD) gene transcription and renal cystogenesis. The Journal of biological chemistry. 2005 Mar; 280(11):10578-86. doi: 10.1074/jbc.m414121200. [PMID: 15647252]
  • A N Hristov, J K Ropp, K L Grandeen, S Abedi, R P Etter, A Melgar, A E Foley. Effect of carbohydrate source on ammonia utilization in lactating dairy cows. Journal of animal science. 2005 Feb; 83(2):408-21. doi: 10.2527/2005.832408x. [PMID: 15644514]
  • M Trotta, R Cavalli, M E Carlotti, L Battaglia, F Debernardi. Solid lipid micro-particles carrying insulin formed by solvent-in-water emulsion-diffusion technique. International journal of pharmaceutics. 2005 Jan; 288(2):281-8. doi: 10.1016/j.ijpharm.2004.10.014. [PMID: 15620868]
  • Jeong-Dong Kim, Kook-Hee Kang. Isolation of Lactobacillus sakei strain KJ-2008 and its removal of characteristic malodorous gases under anaerobic culture conditions. Bioscience, biotechnology, and biochemistry. 2004 Dec; 68(12):2427-35. doi: 10.1271/bbb.68.2427. [PMID: 15618611]