Isobutyric acid (BioDeep_00000002863)

 

Secondary id: BioDeep_00000405471, BioDeep_00000628670, BioDeep_00000868797

natural product human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite BioNovoGene_Lab2019


代谢物信息卡片


Isobutyric acid, sodium salt, 14C-labeled

化学式: C4H8O2 (88.0524)
中文名称: 异丁酸
谱图信息: 最多检出来源 Homo sapiens(blood) 71.81%

Reviewed

Last reviewed on 2024-09-14.

Cite this Page

Isobutyric acid. BioDeep Database v3. PANOMIX ltd, a top metabolomics service provider from China. https://query.biodeep.cn/s/isobutyric_acid (retrieved 2024-12-22) (BioDeep RN: BioDeep_00000002863). Licensed under the Attribution-Noncommercial 4.0 International License (CC BY-NC 4.0).

分子结构信息

SMILES: CC(C(=O)O)C
InChI: InChI=1S/C4H8O2/c1-3(2)4(5)6/h3H,1-2H3,(H,5,6)

描述信息

Isobutyric acid is a carboxylic or short chain fatty acid with characteristic sweat-like smell. Small amount of isobutyrate is generated via microbial (gut) metabolism. Small amounts may also be found in certain foods or fermented beverages. There is anosmia (genetic inability to smell) for the odor of isobutyric acid with a frequency of about 2.5\\%. (OMIM 207000). Isobutyric acid is slightly soluble in water but much more soluble in ethanol, ether and organic solvents. Isobutyric acid can affect people if breathed in and may be absorbed through the skin. Contact can irritate and burn the skin and eyes. Breathing Isobutyric acid can irritate the nose, throat and lungs causing coughing, wheezing and/or shortness of breath.
Present in apple, morello cherry, guava fruit, wine grapes, pineapple, crispbread, other breads, cheeses, wines, scallop and several essential oils, e.g. Roman chamomile. Acid and simple esters used as flavouring agents
KEIO_ID I012

同义名列表

55 个代谢物同义名

Isobutyric acid, sodium salt, 14C-labeled; Isobutyric acid, sodium salt, 11C-labeled; Isobutyric acid, potassium salt; Isobutyric acid, hemiammoniate; Isobutyric acid, ammonium salt; Isobutyric acid, calcium salt; Isobutyric acid, sodium salt; Isobutyric acid, nickel salt; alpha-Methylpropanoic acid; alpha-Methylpropionic acid; 2-METHYL-propionIC ACID; 2,2-Dimethylacetic acid; 2-methyl-propanoic acid; a-Methylpropanoic acid; alpha-Methylpropionate; Α-methylpropanoic acid; a-Methylpropionic acid; 2-Methylpropanoic acid; Α-methylpropionic acid; alpha-Methylpropanoate; 2-Methylpropionic acid; 2-Methylpropionsaeure; alpha-Isobutyric acid; Ammonium isobutyrate; 2-Methpropanoic acid; Isopropylformic acid; 2,2-Dimethylacetate; Dimethylacetic acid; 2-METHYL-propionate; a-Methylpropionate; Α-methylpropanoate; 2-Methylpropanoate; Α-methylpropionate; a-Methylpropanoate; 2-Methylpropionate; Sodium isobutyrate; a-Isobutyric acid; Α-isobutyric acid; alpha-Isobutyrate; Isopropylformate; Isobutanoic acid; Iso-butyric acid; ISOBUTYRIC ACID; Dimethylacetate; Isobuttersaeure; I-butyric acid; Α-isobutyrate; a-Isobutyrate; Iso-C3H7COOH; Iso-butyrate; Isobutanoate; Isobutyrate; I-butyrate; Isobutyric acid; 2-Methylpropanoate



数据库引用编号

29 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

116 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 3 AKT1, ALB, CAT
Peripheral membrane protein 1 HSD17B6
Endoplasmic reticulum membrane 1 CD4
Nucleus 2 AKT1, ALB
cytosol 4 AKT1, ALB, CAT, LIPE
centrosome 1 ALB
nucleoplasm 1 AKT1
Cell membrane 7 AKT1, CD4, CLDN1, FFAR2, FFAR3, LIPE, TNF
lamellipodium 1 AKT1
Early endosome membrane 1 HSD17B6
Multi-pass membrane protein 3 CLDN1, FFAR2, FFAR3
cell cortex 1 AKT1
cell surface 1 TNF
glutamatergic synapse 1 AKT1
Golgi apparatus 2 ALB, ATRN
Golgi membrane 1 INS
neuronal cell body 1 TNF
postsynapse 1 AKT1
Cytoplasm, cytosol 1 LIPE
plasma membrane 8 AKT1, ATRN, CD4, CLDN1, FFAR2, FFAR3, GCG, TNF
Membrane 5 AKT1, CAT, CLDN1, FFAR2, LIPE
apical plasma membrane 1 CLDN1
basolateral plasma membrane 1 CLDN1
caveola 1 LIPE
extracellular exosome 3 ALB, ATRN, CAT
Lumenal side 1 HSD17B6
endoplasmic reticulum 2 ALB, HSD17B6
extracellular space 12 ALB, ATRN, CCL2, CRP, CXCL8, GCG, IL10, IL17A, IL6, INS, PPBP, TNF
Cell junction, tight junction 1 CLDN1
bicellular tight junction 1 CLDN1
mitochondrion 1 CAT
protein-containing complex 4 AKT1, ALB, CAT, CLDN1
intracellular membrane-bounded organelle 2 CAT, HSD17B6
Microsome membrane 1 HSD17B6
Single-pass type I membrane protein 2 ATRN, CD4
Secreted 9 ALB, CCL2, CRP, CXCL8, GCG, IL10, IL17A, IL6, INS
extracellular region 12 ALB, CAT, CCL2, CRP, CXCL8, GCG, IL10, IL17A, IL6, INS, PPBP, TNF
[Isoform 2]: Secreted 1 ATRN
mitochondrial matrix 1 CAT
anchoring junction 1 ALB
external side of plasma membrane 3 CD4, IL17A, TNF
microtubule cytoskeleton 1 AKT1
Early endosome 1 CD4
cell-cell junction 1 AKT1
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
vesicle 1 AKT1
Membrane raft 2 CD4, TNF
focal adhesion 1 CAT
spindle 1 AKT1
Peroxisome 1 CAT
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
Mitochondrion intermembrane space 1 AKT1
mitochondrial intermembrane space 1 AKT1
lateral plasma membrane 1 CLDN1
ciliary basal body 2 AKT1, ALB
cell projection 1 FFAR2
phagocytic cup 1 TNF
centriole 1 ALB
spindle pole 1 ALB
blood microparticle 1 ALB
Basolateral cell membrane 1 CLDN1
[Isoform 3]: Secreted 1 ATRN
endosome lumen 1 INS
Lipid droplet 1 LIPE
Membrane, caveola 1 LIPE
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 3 CAT, GCG, INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 5 ALB, CD4, GCG, IL6, INS
platelet alpha granule lumen 2 ALB, PPBP
tertiary granule lumen 1 PPBP
transport vesicle 1 INS
tight junction 1 CLDN1
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
clathrin-coated endocytic vesicle membrane 1 CD4
[Isoform 1]: Cell membrane 1 ATRN
[Glucagon-like peptide 1]: Secreted 1 GCG
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
T cell receptor complex 1 CD4
catalase complex 1 CAT
interleukin-6 receptor complex 1 IL6
ciliary transition fiber 1 ALB
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

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