Ciliatine (BioDeep_00000002852)

 

Secondary id: BioDeep_00000399898, BioDeep_00000400216, BioDeep_00000408206

natural product human metabolite PANOMIX_OTCML-2023 Endogenous BioNovoGene_Lab2019


代谢物信息卡片


beta-Aminoethylphosphonic acid

化学式: C2H8NO3P (125.0242)
中文名称: 2-氨基乙基膦酸
谱图信息: 最多检出来源 Homo sapiens(plant) 11.78%

分子结构信息

SMILES: C(CP(=O)(O)O)N
InChI: InChI=1S/C2H8NO3P/c3-1-2-7(4,5)6/h1-3H2,(H2,4,5,6)

描述信息

Ciliatine is an organophosphorus compound isolated from human and animal tissues. [HMDB]
Acquisition and generation of the data is financially supported in part by CREST/JST.
Ciliatine is an organophosphorus compound isolated from human and animal tissues.
KEIO_ID A056
(2-Aminoethyl)phosphonic acid is an endogenous metabolite.

同义名列表

21 个代谢物同义名

beta-Aminoethylphosphonic acid; (2-Aminoethane)phosphonic acid; (2-Aminoethyl)phosphonic acid; Acid, 2-aminoethylphosphonic; 2 Aminoethylphosphonic acid; b-Aminoethylphosphonic acid; 2-Aminoethylphosphonic acid; Β-aminoethylphosphonic acid; beta-Aminoethylphosphonate; (2-Aminoethane)phosphonate; Acid, aminoethylphosphonic; (2-Aminoethyl)phosphonate; Aminoethylphosphonic acid; b-Aminoethylphosphonate; 2-Aminoethylphosphonate; Β-aminoethylphosphonate; Aminoethylphosphonate; Phosphonoethylamine; Ciliatine; Ciliatine; 2-Aminoethylphosphonate



数据库引用编号

38 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

31 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 8 ALB, CAT, HMGB1, IGHMBP2, ITPR3, MIOX, PCYT2, TYR
Peripheral membrane protein 4 CLTB, CLTC, HMGB1, MBP
Endosome membrane 1 INSR
Endoplasmic reticulum membrane 3 ITPR3, PCYT2, PEMT
Mitochondrion membrane 1 PEMT
Nucleus 5 ALB, HMGB1, IGHMBP2, MBP, TFAP2A
cytosol 8 ALB, CAT, CLTB, CLTC, GPT, MBP, MIOX, PEMT
mitochondrial membrane 1 PEMT
nuclear body 1 IGHMBP2
trans-Golgi network 1 CLTB
centrosome 1 ALB
nucleoplasm 4 HMGB1, IGHMBP2, ITPR3, TFAP2A
Cell membrane 3 ENPP7, HMGB1, INSR
Cytoplasmic side 3 CLTB, CLTC, MBP
Cell projection, axon 1 IGHMBP2
Multi-pass membrane protein 3 ITPR3, PEMT, RHBDL1
Synapse 1 MBP
cell surface 2 HMGB1, MBP
Golgi apparatus 2 ALB, ENPP7
Golgi membrane 1 INS
growth cone 1 IGHMBP2
neuronal cell body 2 ITPR3, MBP
Lysosome 3 CLTC, INSR, TYR
endosome 2 CLTC, HMGB1
plasma membrane 8 CLTB, CLTC, ENPP7, HMGB1, INSR, ITPR3, MBP, RHBDL1
synaptic vesicle membrane 1 CLTB
Membrane 8 CAT, CLTC, ENPP7, IGHMBP2, INSR, ITPR3, PEMT, RHBDL1
axon 2 IGHMBP2, INSR
brush border 1 ITPR3
caveola 1 INSR
extracellular exosome 7 ALB, BMP3, CAT, CLTC, GPT, INSR, MBP
endoplasmic reticulum 4 ALB, HMGB1, ITPR3, PEMT
extracellular space 4 ALB, BMP3, HMGB1, INS
perinuclear region of cytoplasm 1 TYR
mitochondrion 3 ABAT, CAT, PEMT
protein-containing complex 4 ALB, CAT, CLTC, MBP
intracellular membrane-bounded organelle 4 CAT, CLTB, PEMT, TYR
Single-pass type I membrane protein 3 ENPP7, INSR, TYR
Secreted 4 ALB, BMP3, HMGB1, INS
extracellular region 6 ALB, BMP3, CAT, HMGB1, INS, MBP
neuronal cell body membrane 1 INSR
mitochondrial matrix 2 ABAT, CAT
Extracellular side 1 HMGB1
anchoring junction 1 ALB
ciliary membrane 1 CLTB
external side of plasma membrane 1 INSR
Extracellular vesicle 1 CLTC
nucleolus 1 ITPR3
Melanosome membrane 1 TYR
apical part of cell 1 ITPR3
Golgi-associated vesicle 1 TYR
Cytoplasm, cytoskeleton, spindle 1 CLTC
focal adhesion 2 CAT, CLTC
spindle 1 CLTC
Peroxisome 1 CAT
sarcoplasmic reticulum 1 ITPR3
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
collagen-containing extracellular matrix 1 MBP
nuclear outer membrane 1 ITPR3
Late endosome 1 INSR
receptor complex 2 INSR, ITPR3
ciliary basal body 1 ALB
chromatin 1 TFAP2A
cell periphery 1 MBP
mitotic spindle 1 CLTC
Chromosome 1 HMGB1
[Isoform 3]: Nucleus 1 MBP
centriole 1 ALB
spindle pole 1 ALB
blood microparticle 1 ALB
Endomembrane system 1 CLTC
endosome lumen 1 INS
microvillus 1 ENPP7
[Isoform 1]: Endoplasmic reticulum membrane 1 PEMT
Cytoplasmic vesicle membrane 2 CLTB, CLTC
Melanosome 2 CLTC, TYR
myelin sheath 1 MBP
clathrin-coated vesicle 1 CLTC
trans-Golgi network membrane 1 CLTC
ficolin-1-rich granule lumen 3 CAT, HMGB1, MBP
secretory granule lumen 3 CAT, HMGB1, INS
secretory granule membrane 1 ITPR3
Golgi lumen 1 INS
endoplasmic reticulum lumen 2 ALB, INS
transcription repressor complex 1 HMGB1
platelet alpha granule lumen 1 ALB
transport vesicle 2 INS, MBP
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
clathrin-coated endocytic vesicle 2 CLTB, CLTC
clathrin-coated endocytic vesicle membrane 1 CLTC
ribonucleoprotein complex 1 IGHMBP2
endoplasmic reticulum-Golgi intermediate compartment 1 HMGB1
platelet dense tubular network membrane 1 ITPR3
endolysosome membrane 1 CLTC
clathrin coat of coated pit 2 CLTB, CLTC
dendrite membrane 1 INSR
Cytoplasmic vesicle, secretory vesicle membrane 1 ITPR3
condensed chromosome 1 HMGB1
[Isoform 2]: Endoplasmic reticulum membrane 1 PEMT
Membrane, coated pit 2 CLTB, CLTC
mitotic spindle microtubule 1 CLTC
clathrin vesicle coat 1 CLTB
clathrin coat of trans-Golgi network vesicle 2 CLTB, CLTC
transport vesicle membrane 1 ITPR3
compact myelin 1 MBP
internode region of axon 1 MBP
catalase complex 1 CAT
inclusion body 1 MIOX
alphav-beta3 integrin-HMGB1 complex 1 HMGB1
insulin receptor complex 1 INSR
clathrin coat 2 CLTB, CLTC
clathrin complex 1 CLTC
postsynaptic endocytic zone cytoplasmic component 1 CLTB
presynaptic endocytic zone membrane 1 CLTB
Myb complex 1 CLTC
[Bone marrow proteoglycan]: Secreted 1 MBP
cytoplasmic side of endoplasmic reticulum membrane 1 ITPR3
ciliary transition fiber 1 ALB
Myelin membrane 1 MBP
4-aminobutyrate transaminase complex 1 ABAT


文献列表

  • Andrew R J Murphy, David J Scanlan, Yin Chen, Nathan B P Adams, William A Cadman, Andrew Bottrill, Gary Bending, John P Hammond, Andrew Hitchcock, Elizabeth M H Wellington, Ian D E A Lidbury. Transporter characterisation reveals aminoethylphosphonate mineralisation as a key step in the marine phosphorus redox cycle. Nature communications. 2021 07; 12(1):4554. doi: 10.1038/s41467-021-24646-z. [PMID: 34315891]
  • Nami Tomonaga, Yuki Manabe, Kazuhiko Aida, Tatsuya Sugawara. Dietary ceramide 2-aminoethylphosphonate, a marine sphingophosphonolipid, improves skin barrier function in hairless mice. Scientific reports. 2020 08; 10(1):13891. doi: 10.1038/s41598-020-70888-0. [PMID: 32807849]
  • He Li, Yu Song, Hongwei Zhang, Xuesong Wang, Peixu Cong, Jie Xu, Changhu Xue. Comparative lipid profile of four edible shellfishes by UPLC-Triple TOF-MS/MS. Food chemistry. 2020 Apr; 310(?):125947. doi: 10.1016/j.foodchem.2019.125947. [PMID: 31841939]
  • Nami Tomonaga, Tsuyoshi Tsuduki, Yuki Manabe, Tatsuya Sugawara. Sphingoid bases of dietary ceramide 2-aminoethylphosphonate, a marine sphingolipid, absorb into lymph in rats. Journal of lipid research. 2019 02; 60(2):333-340. doi: 10.1194/jlr.m085654. [PMID: 30552287]
  • Si Zhu, Mengwei Ye, Jilin Xu, Chunyang Guo, Huakun Zheng, Jiabao Hu, Juanjuan Chen, Yajun Wang, Shanliang Xu, Xiaojun Yan. Lipid Profile in Different Parts of Edible Jellyfish Rhopilema esculentum. Journal of agricultural and food chemistry. 2015 Sep; 63(37):8283-91. doi: 10.1021/acs.jafc.5b03145. [PMID: 26322863]
  • Ryan D Ross, Ryan K Roeder. Binding affinity of surface functionalized gold nanoparticles to hydroxyapatite. Journal of biomedical materials research. Part A. 2011 Oct; 99(1):58-66. doi: 10.1002/jbm.a.33165. [PMID: 21793197]
  • Fabienne Le Grand, Edouard Kraffe, Yanic Marty, Ludovic Donaghy, Philippe Soudant. Membrane phospholipid composition of hemocytes in the Pacific oyster Crassostrea gigas and the Manila clam Ruditapes philippinarum. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. 2011 Aug; 159(4):383-91. doi: 10.1016/j.cbpa.2011.04.006. [PMID: 21527350]
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  • C H Patterson, J D Smith. Differential modification of activities of the high-affinity and low-affinity insulin receptors of 3T3-L1 fibroblasts by phosphonolipids in vivo. Biochemical and biophysical research communications. 1996 Nov; 228(1):75-80. doi: 10.1006/bbrc.1996.1618. [PMID: 8912638]
  • F P Castronovo, S Kopiwoda, M Peterson. 2-aminoethylphosphonic acid: biodistribution of a naturally occurring phosphonate after labelling with technetium-99m. Nuclear medicine communications. 1996 Oct; 17(10):902-6. doi: . [PMID: 8951913]
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