Oxidized glutathione (BioDeep_00000002830)

 

Secondary id: BioDeep_00000400236, BioDeep_00000400408, BioDeep_00000409364, BioDeep_00001867946

natural product human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite Toxin BioNovoGene_Lab2019


代谢物信息卡片


(2S)-2-amino-4-{[(1R)-2-{[(2R)-2-[(4S)-4-amino-4-carboxybutanamido]-2-[(carboxymethyl)carbamoyl]ethyl]disulfanyl}-1-[(carboxymethyl)carbamoyl]ethyl]carbamoyl}butanoic acid

化学式: C20H32N6O12S2 (612.152)
中文名称: L-谷胱甘肽(氧化型), L-谷胱甘肽 (氧化型), 谷胱甘肽(氧化型), 氧化谷胱甘肽
谱图信息: 最多检出来源 Homo sapiens(blood) 6.61%

分子结构信息

SMILES: C(CC(=O)NC(CSSCC(C(=O)NCC(=O)O)NC(=O)CCC(C(=O)O)N)C(=O)NCC(=O)O)C(C(=O)O)N
InChI: InChI=1S/C20H32N6O12S2/c21-9(19(35)36)1-3-13(27)25-11(17(33)23-5-15(29)30)7-39-40-8-12(18(34)24-6-16(31)32)26-14(28)4-2-10(22)20(37)38/h9-12H,1-8,21-22H2,(H,23,33)(H,24,34)(H,25,27)(H,26,28)(H,29,30)(H,31,32)(H,35,36)(H,37,38)

描述信息

Oxidized glutathione, also known as glutathione disulfide or GSSG, belongs to the class of organic compounds known as peptides. Peptides are compounds containing an amide derived from two or more amino carboxylic acid molecules (the same or different) by the formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another. In humans, oxidized glutathione is involved in the metabolic disorder called leukotriene C4 synthesis deficiency pathway. Outside of the human body, oxidized glutathione has been detected, but not quantified in several different foods, such as leeks, star anises, mamey sapotes, climbing beans, and common persimmons. Oxidized glutathione is a glutathione dimer formed by a disulfide bond between the cysteine sulfhydryl side chains during the course of being oxidized. Glutathione participates in leukotriene synthesis and is a cofactor for the enzyme glutathione peroxidase. It is also important as a hydrophilic molecule that is added to lipophilic toxins and waste in the liver during biotransformation before they can become part of the bile. Glutathione is also needed for the detoxification of methylglyoxal, a toxin produced as a by-product of metabolism. This detoxification reaction is carried out by the glyoxalase system. Glyoxalase I (EC 4.4.1.5) catalyzes the conversion of methylglyoxal and reduced glutathione into S-D-lactoyl-glutathione. Glyoxalase II (EC 3.1.2.6) catalyzes the hydrolysis of S-D-lactoyl-glutathione into glutathione and D-lactate.
Glutathione disulfide (GSSG) - oxidized glutathione - is a disulfide derived from two glutathione molecules. In living cells, glutathione disulfide is reduced into two molecules of glutathione with reducing equivalents from the coenzyme NADPH. This reaction is catalyzed by the enzyme glutathione reductase. [Wikipedia]. Glutathione disulfide is found in many foods, some of which are jute, millet, malabar plum, and acorn.
[Spectral] Glutathione disulfide (exact mass = 612.15196) and 3,4-Dihydroxy-L-phenylalanine (exact mass = 197.06881) and AMP (exact mass = 347.06308) were not completely separated on HPLC under the present analytical conditions as described in AC$XXX. Additionally some of the peaks in this data contains dimers and other unidentified ions.
[Spectral] Glutathione disulfide (exact mass = 612.15196) and AMP (exact mass = 347.06308) were not completely separated on HPLC under the present analytical conditions as described in AC$XXX. Additionally some of the peaks in this data contains dimers and other unidentified ions.
Acquisition and generation of the data is financially supported in part by CREST/JST.
KEIO_ID G008; [MS2] KO008986
C26170 - Protective Agent
KEIO_ID G008
Glutathione oxidized (L-Glutathione oxidized) is produced by the oxidation of glutathione. Detoxification of reactive oxygen species is accompanied by production of glutathione oxidized. Glutathione oxidized can be used for the research of sickle cells and erythrocytes[1][2].
Glutathione oxidized (GSSG) is produced by the oxidation of glutathione. Detoxification of reactive oxygen species is accompanied by production of glutathione oxidized. Glutathione oxidized can be used for the research of sickle cells and erythrocytes[1].

同义名列表

26 个代谢物同义名

(2S)-2-amino-4-{[(1R)-2-{[(2R)-2-[(4S)-4-amino-4-carboxybutanamido]-2-[(carboxymethyl)carbamoyl]ethyl]disulfanyl}-1-[(carboxymethyl)carbamoyl]ethyl]carbamoyl}butanoic acid; L-Glutathione Oxidized Hexhydrate; OXIDIZED glutathione disulphide; OXIDIZED glutathione disulfide; Glutathione disulfide, ion(1-); L-Glutathione (oxidized form); Glutathione (oxidized form); L-Glutathione oxidized;GSSG; Glutathione-S-S-glutathione; Disulfide, glutathione; Glutathione disulphide; Oxidized L-glutathione; Glutathione, oxidized; Glutathione disulfide; Oxidized glutathione; Oxidised glutathione; Selenoglutathione; L(-)-Glutathione; Glutathione-SSG; Oxiglutatione; Glutathione; GSSG; Oxidized glutathione; L-Glutathione oxidized; Glutathione oxidized; Glutathione disulfide



数据库引用编号

52 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(0)

代谢反应

534 个相关的代谢反应过程信息。

Reactome(52)

BioCyc(3)

WikiPathways(3)

Plant Reactome(475)

INOH(1)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 10 ABCB1, CASP9, CAT, DTNB, G6PD, HPGDS, MAPK14, MAPK8, TXN, XDH
Peripheral membrane protein 1 G6PD
Endoplasmic reticulum membrane 2 HSP90B1, PROS1
Nucleus 8 CASP9, DTNB, GLRX, HSP90B1, MAPK14, MAPK8, MPO, TXN
cytosol 12 CASP9, CAT, G6PD, GCLM, GLRX, GSR, HPGDS, HSP90B1, MAPK14, MAPK8, TXN, XDH
dendrite 1 DTNB
nucleoplasm 6 ATP2B1, HPGDS, MAPK14, MAPK8, MPO, TXN
Cell membrane 3 ABCB1, ABCC1, ATP2B1
Multi-pass membrane protein 3 ABCB1, ABCC1, ATP2B1
Synapse 3 ATP2B1, DTNB, MAPK8
cell surface 1 ABCB1
glutamatergic synapse 2 ATP2B1, MAPK14
Golgi membrane 2 INS, PROS1
postsynapse 1 DTNB
presynaptic membrane 1 ATP2B1
smooth endoplasmic reticulum 1 HSP90B1
Cytoplasm, cytosol 1 G6PD
Lysosome 1 MPO
plasma membrane 5 ABCB1, ABCC1, ATP2B1, DTNB, PROS1
synaptic vesicle membrane 1 ATP2B1
Membrane 6 ABCB1, ABCC1, ATP2B1, CAT, G6PD, HSP90B1
apical plasma membrane 2 ABCB1, ABCC1
axon 1 MAPK8
basolateral plasma membrane 2 ABCC1, ATP2B1
extracellular exosome 11 ABCB1, ABCC1, ATP2B1, CAT, G6PD, GLRX, GSR, HSP90B1, MPO, PROS1, TXN
endoplasmic reticulum 2 HSP90B1, PROS1
extracellular space 5 IL6, INS, MPO, PROS1, XDH
perinuclear region of cytoplasm 1 HSP90B1
mitochondrion 4 CASP9, CAT, GSR, MAPK14
protein-containing complex 3 CASP9, CAT, HSP90B1
intracellular membrane-bounded organelle 5 ATP2B1, CAT, G6PD, HPGDS, MPO
postsynaptic density 1 DTNB
Secreted 4 IL6, INS, PROS1, TXN
extracellular region 8 CAT, HSP90B1, IL6, INS, MAPK14, MPO, PROS1, TXN
cytoplasmic side of plasma membrane 1 G6PD
mitochondrial matrix 2 CAT, GSR
centriolar satellite 1 G6PD
Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane 1 ATP2B1
external side of plasma membrane 1 GSR
midbody 1 HSP90B1
Apical cell membrane 1 ABCB1
focal adhesion 2 CAT, HSP90B1
Peroxisome 2 CAT, XDH
sarcoplasmic reticulum 1 XDH
Peroxisome matrix 1 CAT
peroxisomal matrix 1 CAT
peroxisomal membrane 1 CAT
collagen-containing extracellular matrix 1 HSP90B1
secretory granule 1 MPO
lateral plasma membrane 2 ABCC1, ATP2B1
nuclear speck 1 MAPK14
cell projection 1 ATP2B1
spindle pole 1 MAPK14
blood microparticle 1 PROS1
Basolateral cell membrane 1 ATP2B1
endosome lumen 1 INS
Cell projection, dendrite 1 DTNB
Melanosome 1 HSP90B1
Presynaptic cell membrane 1 ATP2B1
sperm plasma membrane 1 HSP90B1
basal plasma membrane 2 ABCC1, DTNB
azurophil granule 1 MPO
ficolin-1-rich granule lumen 2 CAT, MAPK14
secretory granule lumen 3 CAT, INS, MAPK14
Golgi lumen 2 INS, PROS1
endoplasmic reticulum lumen 3 HSP90B1, IL6, INS
platelet alpha granule lumen 1 PROS1
transport vesicle 1 INS
azurophil granule lumen 1 MPO
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
immunological synapse 1 ATP2B1
apoptosome 1 CASP9
Sarcoplasmic reticulum lumen 1 HSP90B1
phagocytic vesicle lumen 1 MPO
Basal cell membrane 1 DTNB
external side of apical plasma membrane 1 ABCB1
basal dendrite 1 MAPK8
inhibitory synapse 1 DTNB
endocytic vesicle lumen 1 HSP90B1
catalase complex 1 CAT
interleukin-6 receptor complex 1 IL6
endoplasmic reticulum chaperone complex 1 HSP90B1
photoreceptor ribbon synapse 1 ATP2B1
glutamate-cysteine ligase complex 1 GCLM
caspase complex 1 CASP9


文献列表

  • Lara Vogelsang, Jürgen Eirich, Iris Finkemeier, Karl-Josef Dietz. Specificity and dynamics of H2O2 detoxification by the cytosolic redox regulatory network as revealed by in vitro reconstitution. Redox biology. 2024 Jun; 72(?):103141. doi: 10.1016/j.redox.2024.103141. [PMID: 38599017]
  • Wenwen Li, Yu Wang, Yun Zhang, Yuwen Fan, Jinsong Liu, Ke Zhu, Shu Jiang, Jinao Duan. Lizhong decoction ameliorates ulcerative colitis by inhibiting ferroptosis of enterocytes via the Nrf2/SLC7A11/GPX4 pathway. Journal of ethnopharmacology. 2024 May; 326(?):117966. doi: 10.1016/j.jep.2024.117966. [PMID: 38401661]
  • Tianqi Wang, Xiaoju Li, Honglei Liu, Huaiwei Liu, Yongzhen Xia, Luying Xun. Microorganisms uptake zero-valent sulfur via membrane lipid dissolution of octasulfur and intracellular solubilization as persulfide. The Science of the total environment. 2024 Apr; 922(?):170504. doi: 10.1016/j.scitotenv.2024.170504. [PMID: 38307292]
  • Gang He, Yiyuan Zhang, Yanjiao Feng, Tangcong Chen, Mei Liu, Yue Zeng, Xiaojing Yin, Shaokui Qu, Lifen Huang, Youqiang Ke, Li Liang, Jun Yan, Wei Liu. SBFI26 induces triple-negative breast cancer cells ferroptosis via lipid peroxidation. Journal of cellular and molecular medicine. 2024 Apr; 28(7):e18212. doi: 10.1111/jcmm.18212. [PMID: 38516826]
  • Angela Mungala Lengo, Ibrahim Mohamed, Jean-Claude Lavoie. Glutathione Supplementation Prevents Neonatal Parenteral Nutrition-Induced Short- and Long-Term Epigenetic and Transcriptional Disruptions of Hepatic H2O2 Metabolism in Guinea Pigs. Nutrients. 2024 Mar; 16(6):. doi: 10.3390/nu16060849. [PMID: 38542762]
  • Teng Zhang, Meng-Yan Wang, Guo-Dong Wang, Qiu-Yue Lv, Yu-Qian Huang, Peng Zhang, Wen Wang, Yan Zhang, Ya-Ping Bai, Li-Qun Guo. Metformin improves nonalcoholic fatty liver disease in db/db mice by inhibiting ferroptosis. European journal of pharmacology. 2024 Mar; 966(?):176341. doi: 10.1016/j.ejphar.2024.176341. [PMID: 38244761]
  • Diem-Kieu Nguyen, Tri-Phuong Nguyen, Yi-Rong Li, Masaru Ohme-Takagi, Zin-Huang Liu, Thach-Thao Ly, Van-Anh Nguyen, Ngoc-Nam Trinh, Hao-Jen Huang. Comparative study of two indoor microbial volatile pollutants, 2-Methyl-1-butanol and 3-Methyl-1-butanol, on growth and antioxidant system of rice (Oryza sativa) seedlings. Ecotoxicology and environmental safety. 2024 Mar; 272(?):116055. doi: 10.1016/j.ecoenv.2024.116055. [PMID: 38340597]
  • Ariane Coelho Ferraz, Marília Bueno da Silva Menegatto, Rafaela Lameira Souza Lima, Oluwashola Samuel Ola-Olub, Daniela Caldeira Costa, José Carlos de Magalhães, Izabela Maurício Rezende, Angelle Desiree LaBeaud, Thomas P Monath, Pedro Augusto Alves, Andréa Teixeira de Carvalho, Olindo Assis Martins-Filho, Betânia P Drumond, Cintia Lopes de Brito Magalhães. Yellow fever virus infection in human hepatocyte cells triggers an imbalance in redox homeostasis with increased reactive oxygen species production, oxidative stress, and decreased antioxidant enzymes. Free radical biology & medicine. 2024 03; 213(?):266-273. doi: 10.1016/j.freeradbiomed.2024.01.042. [PMID: 38278309]
  • Hongye Fu, Qiong Zhao. CircSCUBE3 promoted ferroptosis to inhibit lung adenocarcinoma progression. Cellular and molecular biology (Noisy-le-Grand, France). 2024 Feb; 70(2):161-168. doi: 10.14715/cmb/2024.70.2.23. [PMID: 38430026]
  • Chen Yan, Fei Xuan. Paris saponin VII promotes ferroptosis to inhibit breast cancer via Nrf2/GPX4 axis. Biochemical and biophysical research communications. 2024 Feb; 697(?):149524. doi: 10.1016/j.bbrc.2024.149524. [PMID: 38252991]
  • Tian Niu, Xin Shi, Xijian Liu, Haiyan Wang, Kun Liu, Yupeng Xu. Porous Se@SiO2 nanospheres alleviate diabetic retinopathy by inhibiting excess lipid peroxidation and inflammation. Molecular medicine (Cambridge, Mass.). 2024 Feb; 30(1):24. doi: 10.1186/s10020-024-00785-z. [PMID: 38321393]
  • Yan-Guang Li, Jiang-Hong Li, Hai-Qin Wang, Junhua Liao, Xiao-Ya Du. Cinnamaldehyde protects cardiomyocytes from oxygen-glucose deprivation/reoxygenation-induced lipid peroxidation and DNA damage via activating the Nrf2 pathway. Chemical biology & drug design. 2024 02; 103(2):e14489. doi: 10.1111/cbdd.14489. [PMID: 38404216]
  • John C Berude, Paul Kennouche, Michelle L Reniere, Daniel A Portnoy. Listeria monocytogenes utilizes glutathione and limited inorganic sulfur compounds as sources of essential cysteine. Infection and immunity. 2024 Jan; ?(?):e0042223. doi: 10.1128/iai.00422-23. [PMID: 38289071]
  • Jianxiong Gui, Lingman Wang, Jie Liu, Hanyu Luo, Dishu Huang, Xiaoyue Yang, Honghong Song, Ziyao Han, Linxue Meng, Ran Ding, Jiaxin Yang, Li Jiang. Ambient particulate matter exposure induces ferroptosis in hippocampal cells through the GSK3B/Nrf2/GPX4 pathway. Free radical biology & medicine. 2024 Jan; 213(?):359-370. doi: 10.1016/j.freeradbiomed.2024.01.045. [PMID: 38290604]
  • Wenliang He, Erin A Posey, Chandler C Steele, Jeffrey W Savell, Fuller W Bazer, Guoyao Wu. Dietary glycine supplementation enhances glutathione availability in tissues of pigs with intrauterine growth restriction. Journal of animal science. 2024 Jan; ?(?):. doi: 10.1093/jas/skae025. [PMID: 38271555]
  • Jesus H Beltran-Ornelas, Diana L Silva-Velasco, Jorge Tapia-Martínez, Araceli Sánchez-López, Edgar Cano-Europa, Saúl Huerta de la Cruz, David Centurión. NaHS reverts chronic stress-induced cardiovascular alterations by reducing oxidative stress. Journal of cardiovascular pharmacology. 2024 Jan; ?(?):. doi: 10.1097/fjc.0000000000001538. [PMID: 38207007]
  • Jiejie Cai, Jingye Pan. Beta vulgaris-derived exosome-like nanovesicles alleviate chronic doxorubicin-induced cardiotoxicity by inhibiting ferroptosis. Journal of biochemical and molecular toxicology. 2024 Jan; 38(1):e23540. doi: 10.1002/jbt.23540. [PMID: 37728183]
  • Xueguang Dong, Xiumei Chen, Yuanhao Zhao, Qunyan Wu, Yuguo Ren. CircTMEM87A promotes the tumorigenesis of gastric cancer by regulating the miR-1276/SLC7A11 axis. Journal of gastroenterology and hepatology. 2024 Jan; 39(1):121-132. doi: 10.1111/jgh.16402. [PMID: 38037531]
  • Wenjie Huang, Fang Wen, Peipei Yang, Ye Li, Qiurong Li, Peng Shu. Yi-qi-hua-yu-jie-du decoction induces ferroptosis in cisplatin-resistant gastric cancer via the AKT/GSK3β/NRF2/GPX4 axis. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2024 Jan; 123(?):155220. doi: 10.1016/j.phymed.2023.155220. [PMID: 38056149]
  • Yue Shi, Xiujie Shi, Mingming Zhao, Yifan Zhang, Qi Zhang, Jing Liu, Hangyu Duan, Bin Yang, Yu Zhang. Ferroptosis is involved in focal segmental glomerulosclerosis in rats. Scientific reports. 2023 12; 13(1):22250. doi: 10.1038/s41598-023-49697-8. [PMID: 38097813]
  • Zalán Czékus, Dávid Milodanovic, Péter Koprivanacz, Krisztina Bela, María F López-Climent, Aurelio Gómez-Cadenas, Péter Poór. The role of salicylic acid on glutathione metabolism under endoplasmic reticulum stress in tomato. Plant physiology and biochemistry : PPB. 2023 Dec; 205(?):108192. doi: 10.1016/j.plaphy.2023.108192. [PMID: 37995576]
  • Gao-Bo Yu, Jin Tian, Ru-Nan Chen, Han-Lin Liu, Bo-Wen Wen, Jin-Peng Wei, Qiu-Sen Chen, Feng-Qiong Chen, Yun-Yan Sheng, Feng-Jun Yang, Chun-Yuan Ren, Yu-Xian Zhang, Golam Jalal Ahammed. Glutathione-dependent redox homeostasis is critical for chlorothalonil detoxification in tomato leaves. Ecotoxicology and environmental safety. 2023 Dec; 268(?):115732. doi: 10.1016/j.ecoenv.2023.115732. [PMID: 38000301]
  • Zexin Qi, Fenglou Ling, Dongsheng Jia, Jingjing Cui, Zhian Zhang, Chen Xu, Lintian Yu, Chenglong Guan, Ye Wang, Mengru Zhang, Jiaqi Dou. Effects of low nitrogen on seedling growth, photosynthetic characteristics and antioxidant system of rice varieties with different nitrogen efficiencies. Scientific reports. 2023 Nov; 13(1):19780. doi: 10.1038/s41598-023-47260-z. [PMID: 37957233]
  • Tie Hu, Hua-Xi Zou, Shu-Yu Le, Ya-Ru Wang, Ya-Mei Qiao, Yong Yuan, Ji-Chun Liu, Song-Qing Lai, Huang Huang. Tanshinone IIA confers protection against myocardial ischemia/reperfusion injury by inhibiting ferroptosis and apoptosis via VDAC1. International journal of molecular medicine. 2023 Nov; 52(5):. doi: 10.3892/ijmm.2023.5312. [PMID: 37800609]
  • Yu Xiao, Changsong Duan, Pushuang Gong, Qi Zhao, Xin Hui Wang, Fang Geng, Jin Zeng, Tianfeng Luo, Yisha Xu, Junning Zhao. Kinsenoside from Anoectochilus roxburghii (Wall.) Lindl. suppressed oxidative stress to attenuate aging-related learning and memory impairment via ERK/Nrf2 pathway. Journal of ethnopharmacology. 2023 Sep; 319(Pt 1):117152. doi: 10.1016/j.jep.2023.117152. [PMID: 37689328]
  • Yang Liu, Aimin Wu, Ruixia Mo, Qiang Zhou, Lianghui Song, Zheng Li, Hua Zhao, Zhengfeng Fang, Yan Lin, Shengyu Xu, Bin Feng, Yong Zhuo, De Wu, Lianqiang Che. Dietary lysolecithin supplementation improves growth performance of weaned piglets via improving nutrients absorption, lipid metabolism and redox status. Journal of animal science. 2023 Sep; ?(?):. doi: 10.1093/jas/skad293. [PMID: 37668533]
  • Germán Muñoz-Sánchez, Lucila A Godínez-Méndez, Mary Fafutis-Morris, Vidal Delgado-Rizo. Effect of Antioxidant Supplementation on NET Formation Induced by LPS In Vitro; the Roles of Vitamins E and C, Glutathione, and N-acetyl Cysteine. International journal of molecular sciences. 2023 Aug; 24(17):. doi: 10.3390/ijms241713162. [PMID: 37685966]
  • Carlos Espírito-Santo, Carmen Alburquerque, Francisco A Guardiola, Rodrigo O A Ozório, Leonardo J Magnoni. Induced swimming modified the antioxidant status of gilthead seabream (Sparus aurata). Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 2023 Aug; 269(?):110893. doi: 10.1016/j.cbpb.2023.110893. [PMID: 37604407]
  • Na Huang, Yu Wei, Meng Liu, Zhen Yang, Kang Yuan, Jingli Chen, Zhixin Wu, Fanghao Zheng, Kaijun Lei, Mingfeng He. Dachaihu decoction ameliorates septic intestinal injury via modulating the gut microbiota and glutathione metabolism as revealed by multi-omics. Journal of ethnopharmacology. 2023 Aug; 312(?):116505. doi: 10.1016/j.jep.2023.116505. [PMID: 37080366]
  • Francisco Javier Romera, María José García, Carlos Lucena, Macarena Angulo, Rafael Pérez-Vicente. NO Is Not the Same as GSNO in the Regulation of Fe Deficiency Responses by Dicot Plants. International journal of molecular sciences. 2023 Aug; 24(16):. doi: 10.3390/ijms241612617. [PMID: 37628796]
  • Zeyu Wang, Weijian Li, Xue Wang, Qin Zhu, Liguo Liu, Shimei Qiu, Lu Zou, Ke Liu, Guoqiang Li, Huijie Miao, Yang Yang, Chengkai Jiang, Yong Liu, Rong Shao, Xu'an Wang, Yingbin Liu. Isoliquiritigenin induces HMOX1 and GPX4-mediated ferroptosis in gallbladder cancer cells. Chinese medical journal. 2023 Jul; ?(?):. doi: 10.1097/cm9.0000000000002675. [PMID: 37488674]
  • Yingzhi Wang, Menglu Xing, Xinru Gao, Min Wu, Fei Liu, Liangliang Sun, Ping Zhang, Ming Duan, Weixin Fan, Jin Xu. Physiological and transcriptomic analyses reveal that phytohormone pathways and glutathione metabolism are involved in the arsenite toxicity response in tomatoes. The Science of the total environment. 2023 Jul; 899(?):165676. doi: 10.1016/j.scitotenv.2023.165676. [PMID: 37481082]
  • Shuyan Li, Shiheng Lu, Lei Wang, Shasha Liu, Lei Zhang, Jialun Du, Ziwen Wu, Xiaojing Huang. Effects of amygdalin on ferroptosis and oxidative stress in diabetic retinopathy progression via the NRF2/ARE signaling pathway. Experimental eye research. 2023 Jul; ?(?):109569. doi: 10.1016/j.exer.2023.109569. [PMID: 37422064]
  • Shi-Hao Ni, Xiao-Jiao Zhang, Xiao-Lu OuYang, Tao-Chun Ye, Jin Li, Yue Li, Shu-Ning Sun, Xiao-Wei Han, Wen-Jie Long, Ling-Jun Wang, Zhong-Qi Yang, Lu Lu. Lobetyolin Alleviates Ferroptosis of Skeletal Muscle in 5/6 Nephrectomized Mice via Activation of Hedgehog-GLI1 Signaling. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2023 Jul; 115(?):154807. doi: 10.1016/j.phymed.2023.154807. [PMID: 37121057]
  • Rizwan Alam, Rizwan Rasheed, Muhammad Arslan Ashraf, Iqbal Hussain, Shafaqat Ali. Allantoin alleviates chromium phytotoxic effects on wheat by regulating osmolyte accumulation, secondary metabolism, ROS homeostasis and nutrient acquisition. Journal of hazardous materials. 2023 Jun; 458(?):131920. doi: 10.1016/j.jhazmat.2023.131920. [PMID: 37413799]
  • F Impellitteri, K Yunko, V Martyniuk, T Matskiv, S Lechachenko, V Khoma, A Mudra, G Piccione, O Stoliar, C Faggio. Physiological and biochemical responses to caffeine and microplastics in Mytilus galloprovincialis. The Science of the total environment. 2023 May; ?(?):164075. doi: 10.1016/j.scitotenv.2023.164075. [PMID: 37230349]
  • Tuo Ji, Lihua Zheng, Jiale Wu, Mei Duan, Qianwen Liu, Peng Liu, Chen Shen, Jinling Liu, Qinyi Ye, Jiangqi Wen, Jiangli Dong, Tao Wang. The thioesterase APT1 is a bidirectional-adjustment redox sensor. Nature communications. 2023 May; 14(1):2807. doi: 10.1038/s41467-023-38464-y. [PMID: 37198152]
  • Rui-Jia Wen, Xin Dong, Hao-Wen Zhuang, Feng-Xiang Pang, Shou-Chang Ding, Nan Li, Yong-Xin Mai, Shu-Ting Zhou, Jun-Yan Wang, Jin-Fang Zhang. Baicalin induces ferroptosis in osteosarcomas through a novel Nrf2/xCT/GPX4 regulatory axis. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2023 May; 116(?):154881. doi: 10.1016/j.phymed.2023.154881. [PMID: 37209607]
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