Thromboxane B2 (BioDeep_00000002514)
Secondary id: BioDeep_00000629602, BioDeep_00001870902
human metabolite Endogenous blood metabolite natural product
代谢物信息卡片
化学式: C20H34O6 (370.2355)
中文名称: 凝血氧烷 B2
谱图信息:
最多检出来源 Homo sapiens(blood) 19.84%
分子结构信息
SMILES: CCCCCC(C=CC1C(C(CC(O1)O)O)CC=CCCCC(=O)O)O
InChI: InChI=1S/C20H34O6/c1-2-3-6-9-15(21)12-13-18-16(17(22)14-20(25)26-18)10-7-4-5-8-11-19(23)24/h4,7,12-13,15-18,20-22,25H,2-3,5-6,8-11,14H2,1H3,(H,23,24)/b7-4-,13-12+/t15-,16-,17-,18+,20-/m0/s1
描述信息
Thromboxanes. A stable, physiologically active compound formed in vivo from the prostaglandin endoperoxides. It is important in the platelet-release reaction (release of ADP and serotonin). -- Pubchem. Thromboxanes are eicosanoids. The eicosanoids consist of the prostaglandins (PGs), thromboxanes (TXs), leukotrienes (LTs), and lipoxins (LXs). The PGs and TXs are collectively identified as prostanoids. Prostaglandins were originally shown to be synthesized in the prostate gland, thromboxanes from platelets (thrombocytes), and leukotrienes from leukocytes, hence the derivation of their names. All mammalian cells except erythrocytes synthesize eicosanoids. These molecules are extremely potent, able to cause profound physiological effects at very dilute concentrations. All eicosanoids function locally at the site of synthesis, through receptor-mediated G-protein linked signalling pathways.
Thromboxanes
同义名列表
9 个代谢物同义名
(5Z)-7-[(2R,3S,4S)-4,6-dihydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]oxan-3-yl]hept-5-enoic acid; (Z)-7-[(2R,3S,4S,6S)-4,6-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]oxan-3-yl]hept-5-enoic acid; 9S,11,15S-trihydroxy-thromboxa-5Z,13E-dien-1-oic acid; TXB2 (Thromboxane B2); b2, Thromboxane; Thromboxane B2; TXB2; PhD; Thromboxane B2
数据库引用编号
32 个数据库交叉引用编号
- ChEBI: CHEBI:182522
- ChEBI: CHEBI:28728
- KEGG: C05963
- PubChem: 5280890
- PubChem: 5283137
- PubChem: 5461
- HMDB: HMDB0003252
- Metlin: METLIN422
- ChEMBL: CHEMBL1552426
- Wikipedia: Thromboxane_B2
- MeSH: Thromboxane B2
- foodb: FDB023130
- chemspider: 4446261
- CAS: 63783-09-5
- CAS: 54397-85-2
- MoNA: UT000370
- MoNA: UT000374
- MoNA: UT000378
- MoNA: UT000371
- MoNA: UT000372
- MoNA: UT000373
- MoNA: UT000376
- MoNA: UT000375
- MoNA: UT000377
- PMhub: MS000003072
- PubChem: 8247
- LipidMAPS: LMFA03030002
- 3DMET: B01937
- NIKKAJI: J37.201C
- RefMet: TXB2
- KNApSAcK: 182522
- LOTUS: LTS0079939
分类词条
相关代谢途径
Reactome(5)
BioCyc(0)
PlantCyc(0)
代谢反应
59 个相关的代谢反应过程信息。
Reactome(5)
- Metabolism:
3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA + CoA-SH ⟶ choloyl-CoA + propionyl CoA
- Metabolism of lipids:
1-3-oxo-THA-CoA + CoA-SH ⟶ DHA-CoA + propionyl CoA
- Fatty acid metabolism:
ATP + PROP-CoA + carbon dioxide ⟶ ADP + MEMA-CoA + Pi
- Arachidonic acid metabolism:
H+ + e- + prostaglandin G2 ⟶ H2O + prostaglandin H2
- Synthesis of Prostaglandins (PG) and Thromboxanes (TX):
H+ + e- + prostaglandin G2 ⟶ H2O + prostaglandin H2
BioCyc(0)
WikiPathways(8)
- Eicosanoid metabolism via cyclooxygenases (COX):
Arachidonic acid ⟶ 15(S)-HETE
- Folate metabolism:
Thromboxane A2 ⟶ Thromboxane B2
- Vitamin B12 metabolism:
Thromboxane A2 ⟶ Thromboxane B2
- Selenium micronutrient network:
Ascorbic acid ⟶ Dehydroascorbic acid
- Selenium micronutrient network:
Ascorbic acid ⟶ Dehydroascorbic acid
- Vitamin B12 metabolism:
Thromboxane A2 ⟶ Thromboxane B2
- Folate metabolism:
Thromboxane A2 ⟶ Thromboxane B2
- Arachidonic acid (AA, ARA) oxylipin metabolism:
HXB3 ⟶ Trioxilin B3
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(46)
- Leukotriene C4 Synthesis Deficiency:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Piroxicam Action Pathway:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Acetylsalicylic Acid Action Pathway:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Etodolac Action Pathway:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Ketoprofen Action Pathway:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Ibuprofen Action Pathway:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Rofecoxib Action Pathway:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Diclofenac Action Pathway:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Sulindac Action Pathway:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Celecoxib Action Pathway:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Ketorolac Action Pathway:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Suprofen Action Pathway:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Bromfenac Action Pathway:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Indomethacin Action Pathway:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Mefenamic Acid Action Pathway:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Oxaprozin Action Pathway:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Nabumetone Action Pathway:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Naproxen Action Pathway:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Diflunisal Action Pathway:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Meloxicam Action Pathway:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Valdecoxib Action Pathway:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Antipyrine Action Pathway:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Antrafenine Action Pathway:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Carprofen Action Pathway:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Etoricoxib Action Pathway:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Fenoprofen Action Pathway:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Flurbiprofen Action Pathway:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Magnesium Salicylate Action Pathway:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Lumiracoxib Action Pathway:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Lornoxicam Action Pathway:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Phenylbutazone Action Pathway:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Arachidonic Acid Metabolism:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Trisalicylate-Choline Action Pathway:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Tolmetin Action Pathway:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Tiaprofenic Acid Action Pathway:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Tenoxicam Action Pathway:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Salsalate Action Pathway:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Salicylate-Sodium Action Pathway:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Nepafenac Action Pathway:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Acetaminophen Action Pathway:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Arachidonic Acid Metabolism:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Leukotriene C4 Synthesis Deficiency:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Arachidonic Acid Metabolism:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Arachidonic Acid Metabolism:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Leukotriene C4 Synthesis Deficiency:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
- Salicylic Acid Action Pathway:
Glutathione + Leukotriene A4 ⟶ Leukotriene C4
PharmGKB(0)
15 个相关的物种来源信息
- 7458 - Apidae: LTS0079939
- 7459 - Apis: LTS0079939
- 7461 - Apis cerana: 10.1371/JOURNAL.PONE.0175573
- 7461 - Apis cerana: LTS0079939
- 6656 - Arthropoda: LTS0079939
- 7711 - Chordata: LTS0079939
- 2759 - Eukaryota: LTS0079939
- 9604 - Hominidae: LTS0079939
- 9605 - Homo: LTS0079939
- 9606 - Homo sapiens: -
- 9606 - Homo sapiens: 10.1038/NBT.2488
- 9606 - Homo sapiens: LTS0079939
- 50557 - Insecta: LTS0079939
- 40674 - Mammalia: LTS0079939
- 33208 - Metazoa: LTS0079939
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Neven Žarković, Wojciech Łuczaj, Iwona Jarocka-Karpowicz, Biserka Orehovec, Bruno Baršić, Marko Tarle, Marta Kmet, Ivica Lukšić, Michał Biernacki, Elżbieta Skrzydlewska. Diversified Effects of COVID-19 as a Consequence of the Differential Metabolism of Phospholipids and Lipid Peroxidation Evaluated in the Plasma of Survivors and Deceased Patients upon Admission to the Hospital.
International journal of molecular sciences.
2022 Oct; 23(19):. doi:
10.3390/ijms231911810
. [PMID: 36233111] - Jeffrey J Rade, Bruce A Barton, Ramachandran S Vasan, Shari S Kronsberg, Vanessa Xanthakis, John F Keaney, Naomi M Hamburg, Nikolaos Kakouros, Thomas A Kickler. Association of Thromboxane Generation With Survival in Aspirin Users and Nonusers.
Journal of the American College of Cardiology.
2022 07; 80(3):233-250. doi:
10.1016/j.jacc.2022.04.034
. [PMID: 35660296] - Essa Hariri, Nikolaos Kakouros, David A Bunsick, Stuart D Russell, James O Mudd, Katherine Laws, Mikhailia W Lake, Jeffrey J Rade. Nonplatelet thromboxane generation is associated with impaired cardiovascular performance and mortality in heart failure.
American journal of physiology. Heart and circulatory physiology.
2022 07; 323(1):H248-H255. doi:
10.1152/ajpheart.00212.2022
. [PMID: 35714178] - Alexander A Boucher, Brenton J Francisco, Amanda Pfeiffer, Matthew Martin, Janine Martin, Amy Shova, Jaimie D Nathan, Gregory M Tiao, Lori Luchtman-Jones. Urinary 11-dehydrothromboxane B2 aspirin efficacy testing is sensitive to perioperative inflammation in pediatric solid-organ transplant patients.
Pediatric blood & cancer.
2022 02; 69(2):e29413. doi:
10.1002/pbc.29413
. [PMID: 34676969] - Maeve Kiely, Ginger L Milne, Tsion Z Minas, Tiffany H Dorsey, Wei Tang, Cheryl J Smith, Francine Baker, Christopher A Loffredo, Clayton Yates, Michael B Cook, Stefan Ambs. Urinary Thromboxane B2 and Lethal Prostate Cancer in African American Men.
Journal of the National Cancer Institute.
2022 01; 114(1):123-129. doi:
10.1093/jnci/djab129
. [PMID: 34264335] - Mingwen Yang, Zekang Ye, Lianlian Mei, Inam Ullah, Chuchu Tan, Guoyu Wang, Qian Gu, Yi Lu, Samee Abdus, Lu Shi, Xiaoxuan Gong, Jianling Bai, John W Eikelboom, Chunjian Li. Pharmacodynamic effects of indobufen compared with aspirin in patients with coronary atherosclerosis.
European journal of clinical pharmacology.
2021 Dec; 77(12):1815-1823. doi:
10.1007/s00228-021-03177-y
. [PMID: 34331551] - Pandarisamy Sundaravadivel, Rita Christopher, Nitin Ramanujam, Sadanandavalli Retnaswami Chandra. Serum thromboxane B2 but not soluble P-selectin levels identify ischemic stroke patients with persistent platelet reactivity while on aspirin therapy.
Thrombosis research.
2021 Dec; 208(?):92-98. doi:
10.1016/j.thromres.2021.10.021
. [PMID: 34742142] - Theresa Wolfram, Leonie M Weidenbach, Johanna Adolf, Maria Schwarz, Patrick Schädel, André Gollowitzer, Oliver Werz, Andreas Koeberle, Anna P Kipp, Solveigh C Koeberle. The Trace Element Selenium Is Important for Redox Signaling in Phorbol Ester-Differentiated THP-1 Macrophages.
International journal of molecular sciences.
2021 Oct; 22(20):. doi:
10.3390/ijms222011060
. [PMID: 34681720] - Silvia Lee, Beate Eichelberger, Christoph W Kopp, Simon Panzer, Thomas Gremmel. Residual platelet reactivity in low-dose aspirin-treated patients with class 1 obesity.
Vascular pharmacology.
2021 02; 136(?):106819. doi:
10.1016/j.vph.2020.106819
. [PMID: 33207279] - Anindita A Nandi, Nisha S Wadhwani, Karuna N Randhir, Shweta D Madiwale, Juilee S Deshpande, Girija N Wagh, Sadhana R Joshi. Maternal vitamin D deficiency influences long-chain polyunsaturated fatty acids and pregnancy outcome in association with alterations in one-carbon metabolism.
Nutrition research (New York, N.Y.).
2021 02; 86(?):37-49. doi:
10.1016/j.nutres.2020.11.009
. [PMID: 33482597] - Paul A Gurbel, Kevin P Bliden, Udaya S Tantry. Defining platelet response to acetylsalicylic acid: the relation between inhibition of serum thromboxane B2 and agonist-induced platelet aggregation.
Journal of thrombosis and thrombolysis.
2021 Feb; 51(2):260-264. doi:
10.1007/s11239-020-02334-x
. [PMID: 33170486] - Miltan Chandra Roy, Kiwoong Nam, Jaesu Kim, David Stanley, Yonggyun Kim. Thromboxane Mobilizes Insect Blood Cells to Infection Foci.
Frontiers in immunology.
2021; 12(?):791319. doi:
10.3389/fimmu.2021.791319
. [PMID: 34987515] - Beatrice Mainoli, Gonçalo S Duarte, João Costa, Joaquim Ferreira, Daniel Caldeira. Once- versus Twice-Daily Aspirin in Patients at High Risk of Thrombotic Events: Systematic Review and Meta-Analysis.
American journal of cardiovascular drugs : drugs, devices, and other interventions.
2021 Jan; 21(1):63-71. doi:
10.1007/s40256-020-00409-x
. [PMID: 32394295] - Yao Tang, Sunhua Huang, Wenhao Lin, Ke Wen, Zhexuan Lin, Ming Han. Arachidonic Acid-Dependent Pathway Inhibition in Platelets: its Role in Multiple Injury-Induced Coagulopathy and the Potential Mechanisms.
Shock (Augusta, Ga.).
2021 01; 55(1):121-127. doi:
10.1097/shk.0000000000001563
. [PMID: 32433211] - Jia Ke, Meng-Ting Li, Ya-Jing Huo, Yan-Qiong Cheng, Shu-Fen Guo, Yang Wu, Lei Zhang, Jianpeng Ma, Ai-Jun Liu, Yan Han. The Synergistic Effect of Ginkgo biloba Extract 50 and Aspirin Against Platelet Aggregation.
Drug design, development and therapy.
2021; 15(?):3543-3560. doi:
10.2147/dddt.s318515
. [PMID: 34429584] - Mariangela Scavone, Jessica Rizzo, Eti A Femia, Gian Marco Podda, Elena Bossi, Sabrina Caberlon, Rita Paroni, Marco Cattaneo. Patients with Essential Thrombocythemia may be Poor Responders to Enteric-Coated Aspirin, but not to Plain Aspirin.
Thrombosis and haemostasis.
2020 Oct; 120(10):1442-1453. doi:
10.1055/s-0040-1714351
. [PMID: 32717754] - Marie Michèle Boulet, David Cheillan, Mathilde Di Filippo, Taïssia Lelekov-Boissard, Charline Buisson, Stéphanie Lambert-Porcheron, Julie-Anne Nazare, Jessica Tressou, Marie-Caroline Michalski, Catherine Calzada, Philippe Moulin. Postprandial Triglyceride-Rich Lipoproteins from Type 2 Diabetic Women Stimulate Platelet Activation Regardless of the Fat Source in the Meal.
Molecular nutrition & food research.
2020 10; 64(19):e2000694. doi:
10.1002/mnfr.202000694
. [PMID: 32844550] - Tessa J Barrett, Angela H Lee, Yuhe Xia, Lawrence H Lin, Margaret Black, Paolo Cotzia, Judith Hochman, Jeffrey S Berger. Platelet and Vascular Biomarkers Associate With Thrombosis and Death in Coronavirus Disease.
Circulation research.
2020 09; 127(7):945-947. doi:
10.1161/circresaha.120.317803
. [PMID: 32757722] - Elżbieta Cecerska-Heryć, Rafał Heryć, Magda Wiśniewska, Natalia Serwin, Bartłomiej Grygorcewicz, Barbara Dołęgowska. Effect of renal replacement therapy on selected arachidonic acid derivatives concentration.
BMC nephrology.
2020 09; 21(1):394. doi:
10.1186/s12882-020-02053-8
. [PMID: 32917166] - Laura Lucarini, Mariaconcetta Durante, Silvia Sgambellone, Cecilia Lanzi, Elisabetta Bigagli, Ozlem Akgul, Emanuela Masini, Claudiu T Supuran, Fabrizio Carta. Effects of New NSAID-CAI Hybrid Compounds in Inflammation and Lung Fibrosis.
Biomolecules.
2020 09; 10(9):. doi:
10.3390/biom10091307
. [PMID: 32927723] - Pavel Chrbolka, Stefan Alusik, Dagmar Kalatova, Zoltan Paluch. Increased platelet activity in tinnitus patients.
Neuro endocrinology letters.
2020 Sep; 41(2):102-106. doi:
. [PMID: 33185996]
- Tomokazu Tokoro, Isamu Makino, Shinichi Harada, Koichi Okamoto, Shinichi Nakanuma, Seisho Sakai, Jun Kinoshita, Keishi Nakamura, Tomoharu Miyashita, Hidehiro Tajima, Itasu Ninomiya, Sachio Fushida, Tetsuo Ohta. Interactions Between Neutrophils and Platelets in the Progression of Acute Pancreatitis.
Pancreas.
2020 07; 49(6):830-836. doi:
10.1097/mpa.0000000000001585
. [PMID: 32541639] - Yeek Tat Ng, Sonia Chew Wen Phang, Gerald Chen Jie Tan, En Yng Ng, Nevein Philip Botross Henien, Uma Devi M Palanisamy, Badariah Ahmad, Khalid Abdul Kadir. The Effects of Tocotrienol-Rich Vitamin E (Tocovid) on Diabetic Neuropathy: A Phase II Randomized Controlled Trial.
Nutrients.
2020 May; 12(5):. doi:
10.3390/nu12051522
. [PMID: 32456230] - Jiawen Huang, Xiangyu Wang, Liyuan Xie, Mingan Wu, Wei Zhao, Yongbin Zhang, Qi Wang, Limei Yao, Weirong Li. Extract of Danggui-Shaoyao-San ameliorates cognition deficits by regulating DHA metabolism in APP/PS1 mice.
Journal of ethnopharmacology.
2020 May; 253(?):112673. doi:
10.1016/j.jep.2020.112673
. [PMID: 32084555] - Michael S Garshick, Michael Tawil, Tessa J Barrett, Charissa M Salud-Gnilo, Michael Eppler, Angela Lee, Jose U Scher, Andrea L Neimann, Sanja Jelic, Nehal N Mehta, Edward A Fisher, James G Krueger, Jeffrey S Berger. Activated Platelets Induce Endothelial Cell Inflammatory Response in Psoriasis via COX-1.
Arteriosclerosis, thrombosis, and vascular biology.
2020 05; 40(5):1340-1351. doi:
10.1161/atvbaha.119.314008
. [PMID: 32131611] - Mohamed Nabil Elshafei, Yahia Imam, Mouhand F H Mohamed, Arwa Ebrahim AlSaud, Mohamed Sayed Ahmed, Khaldun Obeidat, Razan Saeid, Mohamed Ali, Ibtihal M Abdallah, Aeijaz Sultan Parray, Mohammed Ibn-Masoud Danjuma. An investigation into the impact of enteric coated of aspirin in patients with newly diagnosed ischemic stroke (ECASIS).
Medicine.
2020 May; 99(20):e20307. doi:
10.1097/md.0000000000020307
. [PMID: 32443379] - Kijeong Lee, Sang Hag Lee, Tae Hoon Kim. The Biology of Prostaglandins and Their Role as a Target for Allergic Airway Disease Therapy.
International journal of molecular sciences.
2020 Mar; 21(5):. doi:
10.3390/ijms21051851
. [PMID: 32182661] - Malgorzata Cebo, Jörg Schlotterbeck, Meinrad Gawaz, Madhumita Chatterjee, Michael Lämmerhofer. Simultaneous targeted and untargeted UHPLC-ESI-MS/MS method with data-independent acquisition for quantification and profiling of (oxidized) fatty acids released upon platelet activation by thrombin.
Analytica chimica acta.
2020 Jan; 1094(?):57-69. doi:
10.1016/j.aca.2019.10.005
. [PMID: 31761048] - Vikas Kumar, A Aneesh Kumar, Vinod Joseph, Vipin Mohan Dan, Abdul Jaleel, T R Santhosh Kumar, Chandrasekharan C Kartha. Untargeted metabolomics reveals alterations in metabolites of lipid metabolism and immune pathways in the serum of rats after long-term oral administration of Amalaki rasayana.
Molecular and cellular biochemistry.
2020 Jan; 463(1-2):147-160. doi:
10.1007/s11010-019-03637-1
. [PMID: 31595424] - Giusy Tiseo, Elena Cavarretta, Arianna Forniti, Cristina Nocella, Sebastiano Sciarretta, Ornella Spagnolello, Enrico Baldini, Mariangela Peruzzi, Giuliano Bertazzoni, Francesco Menichetti, Antonino G M Marullo, Fabio Miraldi, Andrea Morelli, Giacomo Frati, Roberto Carnevale, Falcone Marco. Interplay between Nox2 Activity and Platelet Activation in Patients with Sepsis and Septic Shock: A Prospective Study.
Oxidative medicine and cellular longevity.
2020; 2020(?):4165358. doi:
10.1155/2020/4165358
. [PMID: 33194001] - Changqin Li, Miyun Hu, Shengjun Jiang, Zhenhua Liang, Jinmei Wang, Zhenhua Liu, Hui-Min David Wang, Wenyi Kang. Evaluation Procoagulant Activity and Mechanism of Astragalin.
Molecules (Basel, Switzerland).
2020 Jan; 25(1):. doi:
10.3390/molecules25010177
. [PMID: 31906332] - Ramona C Dolscheid-Pommerich, Juliane Weikert, Madlen Reinicke, Rolf Fimmers, Birgit Stoffel-Wagner, Felix Erdfelder, Uta Ceglarek, Lars Eichhorn. Changes in PUFA and eicosanoid metabolism during/after apnea diving: a prospective single-center study.
Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc.
2020 Fou; 47(4):539-549. doi:
. [PMID: 33227829]
- Xuqiang Liu, Jing Dong, Qiongxin Liang, Hui-Min David Wang, Zhenhua Liu, Ruian Xu, Wenyi Kang. Coagulant Effects and Mechanism of Schefflera heptaphylla (L.) Frodin.
Molecules (Basel, Switzerland).
2019 Dec; 24(24):. doi:
10.3390/molecules24244547
. [PMID: 31842361] - H Patrick MacKnight, Daniel J Stephenson, L Alexis Hoeferlin, Savannah D Benusa, James T DeLigio, Kenneth D Maus, Anika N Ali, Jennifer S Wayne, Margaret A Park, Edward H Hinchcliffe, Rhoderick E Brown, John J Ryan, Robert F Diegelmann, Charles E Chalfant. The interaction of ceramide 1-phosphate with group IVA cytosolic phospholipase A2 coordinates acute wound healing and repair.
Science signaling.
2019 12; 12(610):. doi:
10.1126/scisignal.aav5918
. [PMID: 31796632] - Minghui Ou, Yunfeng Zhang, Shichao Cui, Shibo Zhao, Jie Tu. Upregulated MiR-9-5p Protects Against Inflammatory Response in Rats with Deep Vein Thrombosis via Inhibition of NF-κB p50.
Inflammation.
2019 Dec; 42(6):1925-1938. doi:
10.1007/s10753-019-01031-z
. [PMID: 31463646] - Patrudu Makena, Gang Liu, Peter Chen, Charles R Yates, G L Prasad. Urinary Leukotriene E4 and 2,3-Dinor Thromboxane B2 Are Biomarkers of Potential Harm in Short-Term Tobacco Switching Studies.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.
2019 Dec; 28(12):2095-2105. doi:
10.1158/1055-9965.epi-19-0342
. [PMID: 31558507] - Dominick J Angiolillo, Deepak L Bhatt, Frank Lanza, Byron Cryer, Jin-Fei Dong, Walter Jeske, Ronald R Zimmerman, Estela von Chong, Jayne Prats, Efthymios N Deliargyris, Upendra Marathi. Pharmacokinetic/pharmacodynamic assessment of a novel, pharmaceutical lipid-aspirin complex: results of a randomized, crossover, bioequivalence study.
Journal of thrombosis and thrombolysis.
2019 Nov; 48(4):554-562. doi:
10.1007/s11239-019-01933-7
. [PMID: 31420787] - Chunpeng Lu, Yanping Yin, Yongliang Cui, Lili Wang, Yan Bai, Jian Li, Tingting Huang, Maimaiti Reziwanguli, Lifu Miao. 1,25(OH)2D3 improves blood lipid metabolism, liver function, and atherosclerosis by constraining the TGF-β/Smad signaling pathway in rats with hyperlipidemia.
Cell cycle (Georgetown, Tex.).
2019 Nov; 18(22):3111-3124. doi:
10.1080/15384101.2019.1669389
. [PMID: 31544583] - Remo H M Furtado, Robert P Giugliano, Talia F Dalcoquio, Flavia B B Arantes, Carlos J D G Barbosa, Paulo R R Genestreti, André Franci, Fernando R Menezes, Carlos A K Nakashima, Marco A Scanavini Filho, Aline G Ferrari, Rocio Salsoso, Luciano M Baracioli, Jose C Nicolau. Increased bodyweight and inadequate response to aspirin in individuals with coronary artery disease.
Journal of thrombosis and thrombolysis.
2019 Aug; 48(2):217-224. doi:
10.1007/s11239-019-01830-z
. [PMID: 30879169] - R Morchón, E Carretón, R García, T Zueva, V Kartashev, F Simón. A possible relationship between Thromboxane B2 and Leukotriene B4 and the encapsulation of Dirofilaria repens worms in human subcutaneous dirofilariasis.
Journal of helminthology.
2019 Jul; 94(?):e67. doi:
10.1017/s0022149x19000464
. [PMID: 31339092] - Pankamol Sirivadhanakul, Ampaiwan Chuansumrit, Duantida Songdej, Praguywan Kadegasem, Pakawan Wongwerawattanakoon, Nongnuch Sirachainan. Increased endothelial activation in α-thalassemia disease.
Annals of hematology.
2019 Jul; 98(7):1593-1602. doi:
10.1007/s00277-019-03672-4
. [PMID: 30953084] - Chandra Prakash Pandey, Ankita Misra, Mahendra Pal Singh Negi, Babu Nageswararao Kanuri, Yashpal Singh Chhonker, Rabi Shanker Bhatta, Varun Shanker Narain, Madhu Dikshit. Aspirin & clopidogrel non-responsiveness & its association with genetic polymorphisms in patients with myocardial infarction.
The Indian journal of medical research.
2019 07; 150(1):50-61. doi:
10.4103/ijmr.ijmr_782_17
. [PMID: 31571629] - Chikako Sakaguchi, Naoki Miura, Hiromi Ohara, Yasufumi Nagata. Effects of reduced exposure to cigarette smoking on changes in biomarkers of potential harm in adult smokers: results of combined analysis of two clinical studies.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals.
2019 Jul; 24(5):457-468. doi:
10.1080/1354750x.2019.1609579
. [PMID: 31084221] - Anindita A Nandi, Nisha S Wadhwani, Sadhana R Joshi. Maternal vitamin D deficiency increases the thromboxane/prostacyclin ratio through alterations in the one-carbon cycle in Wistar rats.
BioFactors (Oxford, England).
2019 Jul; 45(4):548-555. doi:
10.1002/biof.1510
. [PMID: 30985971] - Giovanna Petrucci, Francesco Zaccardi, Alberto Giaretta, Viviana Cavalca, Esmeralda Capristo, Carmine Cardillo, Dario Pitocco, Benedetta Porro, Francesca Schinzari, Gianna Toffolo, Elena Tremoli, Bianca Rocca. Obesity is associated with impaired responsiveness to once-daily low-dose aspirin and in vivo platelet activation.
Journal of thrombosis and haemostasis : JTH.
2019 06; 17(6):885-895. doi:
10.1111/jth.14445
. [PMID: 30933424] - Chun-Cai Zou, Hai-Yan Yan, Li-Li Wang, Ying-Ying Bian. [Anti-platelet aggregation and anti-thrombotic mechanism of Trichosanthis Fructus combined with aspirin based on network pharmacology].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2019 Apr; 44(8):1654-1659. doi:
10.19540/j.cnki.cjcmm.20190111.003
. [PMID: 31090331] - Cati Racca, Jeske Joanna Katarina van Diemen, Wessel Willem Fuijkschot, Karlinde Spit, Tobias Nicolaas Bonten, Mattijs Everard Numans, Johanna Gerarda van der Bom, Yvo Michiel Smulders, Abel Thijs. Aspirin intake in the morning is associated with suboptimal platelet inhibition, as measured by serum Thromboxane B2, during infarct-prone early-morning hours.
Platelets.
2019; 30(7):871-877. doi:
10.1080/09537104.2018.1528347
. [PMID: 30346860] - Helga Helgadóttir, Ísleifur Ólafsson, Karl Andersen, Sveinbjörn Gizurarson. Stability of thromboxane in blood samples.
Vascular health and risk management.
2019; 15(?):143-147. doi:
10.2147/vhrm.s204925
. [PMID: 31239692] - Rena Kasimu, Xinling Wang, Xiaomei Wang, Junping Hu, Xiaoqing Wang, Yuming Mu. Antithrombotic effects and related mechanisms of Salvia deserta Schang root EtOAc extracts.
Scientific reports.
2018 12; 8(1):17753. doi:
10.1038/s41598-018-36026-7
. [PMID: 30532017] - Paola Simeone, Rossella Liani, Romina Tripaldi, Augusto Di Castelnuovo, Maria Teresa Guagnano, Armando Tartaro, Riccardo C Bonadonna, Virginia Federico, Francesco Cipollone, Agostino Consoli, Francesca Santilli. Thromboxane-Dependent Platelet Activation in Obese Subjects with Prediabetes or Early Type 2 Diabetes: Effects of Liraglutide- or Lifestyle Changes-Induced Weight Loss.
Nutrients.
2018 Dec; 10(12):. doi:
10.3390/nu10121872
. [PMID: 30513818] - A Kij, K Kus, M Smeda, A Zakrzewska, B Proniewski, K Matyjaszczyk, A Jasztal, M Stojak, M Walczak, S Chlopicki. Differential effects of nitric oxide deficiency on primary tumour growth, pulmonary metastasis and prostacyclin/thromboxane A2 balance in orthotopic and intravenous murine models of 4T1 breast cancer.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society.
2018 Dec; 69(6):. doi:
10.26402/jpp.2018.6.05
. [PMID: 30802213] - Mohammed E Al-Sofiani, Lisa R Yanek, Nauder Faraday, Brian G Kral, Rasika Mathias, Lewis C Becker, Diane M Becker, Dhananjay Vaidya, Rita R Kalyani. Diabetes and Platelet Response to Low-Dose Aspirin.
The Journal of clinical endocrinology and metabolism.
2018 12; 103(12):4599-4608. doi:
10.1210/jc.2018-01254
. [PMID: 30265320] - Paola Simeone, Andrea Boccatonda, Rossella Liani, Francesca Santilli. Significance of urinary 11-dehydro-thromboxane B2 in age-related diseases: Focus on atherothrombosis.
Ageing research reviews.
2018 12; 48(?):51-78. doi:
10.1016/j.arr.2018.09.004
. [PMID: 30273676] - Yu He, Xiaohui Lou, Zhan Jin, Li Yu, Ling Deng, Haitong Wan. Mahuang decoction mitigates airway inflammation and regulates IL-21/STAT3 signaling pathway in rat asthma model.
Journal of ethnopharmacology.
2018 Oct; 224(?):373-380. doi:
10.1016/j.jep.2018.06.011
. [PMID: 29906536] - Anupama Vasudevan, Kristen M Tecson, Jeanna Bennett-Firmin, Teodoro Bottiglieri, Luis R Lopez, Margarita Peterson, Mohanakrishnan Sathyamoorthy, Raphael Schiffmann, Jeffrey M Schussler, Caren Swift, Carlos E Velasco, Peter A McCullough. Prognostic value of urinary 11-dehydro-thromboxane B2 for mortality: A cohort study of stable coronary artery disease patients treated with aspirin.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.
2018 10; 92(4):653-658. doi:
10.1002/ccd.27437
. [PMID: 29193683] - Yezhe Cheng, Yanjie Chu, Xitong Su, Kexia Zhang, Yu Zhang, Zhenzhong Wang, Wei Xiao, Longshan Zhao, Xiaohui Chen. Pharmacokinetic-pharmacodynamic modeling to study the anti-dysmenorrhea effect of Guizhi Fuling capsule on primary dysmenorrhea rats.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2018 Sep; 48(?):141-151. doi:
10.1016/j.phymed.2018.04.041
. [PMID: 30195872] - Lili Cui, Meimei Xing, Lanting Xu, Junya Wang, Xiaofeng Zhang, Changyang Ma, Wenyi Kang. Antithrombotic components of Malus halliana Koehne flowers.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2018 Sep; 119(?):326-333. doi:
10.1016/j.fct.2018.02.049
. [PMID: 29496530] - Tomoko Nakao, Atsushi Yasumoto, Suzumi Tokuoka, Yoshihiro Kita, Takuya Kawahara, Masao Daimon, Yutaka Yatomi. The impact of night-shift work on platelet function in healthy medical staff.
Journal of occupational health.
2018 Jul; 60(4):324-332. doi:
10.1539/joh.2018-0027-fs
. [PMID: 29669967] - Dorottya Nagy-Szakal, Dinesh K Barupal, Bohyun Lee, Xiaoyu Che, Brent L Williams, Ellie J R Kahn, Joy E Ukaigwe, Lucinda Bateman, Nancy G Klimas, Anthony L Komaroff, Susan Levine, Jose G Montoya, Daniel L Peterson, Bruce Levin, Mady Hornig, Oliver Fiehn, W Ian Lipkin. Insights into myalgic encephalomyelitis/chronic fatigue syndrome phenotypes through comprehensive metabolomics.
Scientific reports.
2018 07; 8(1):10056. doi:
10.1038/s41598-018-28477-9
. [PMID: 29968805] - John M Thomason, Todd M Archer, Robert W Wills, Andrew J Mackin. Effects of immunosuppressive agents on the hemostatic system in normal dogs.
Journal of veterinary internal medicine.
2018 Jul; 32(4):1325-1333. doi:
10.1111/jvim.15132
. [PMID: 29749651] - Hewang Lee, Hila Roshanravan, Ying Wang, Koji Okamoto, Junghwa Ryu, Shashi Shrivastav, Peng Qu, Jeffrey B Kopp. ApoL1 renal risk variants induce aberrant THP-1 monocyte differentiation and increase eicosanoid production via enhanced expression of cyclooxygenase-2.
American journal of physiology. Renal physiology.
2018 07; 315(1):F140-F150. doi:
10.1152/ajprenal.00254.2017
. [PMID: 29357411] - Stefania Tacconelli, Melania Dovizio, Luigia Di Francesco, Alessandra Meneguzzi, Ilaria D'Agostino, Virgilio Evangelista, Stefano Manarini, Marta L Capone, Linda Grossi, Ettore Porreca, Concetta Di Febbo, Annalisa Bruno, Patrizia Ballerini, Giacomo Levantesi, Cristiano Fava, Pietro Minuz, Paola Patrignani. Reduced Variability to Aspirin Antiplatelet Effect by the Coadministration of Statins in High-Risk Patients for Cardiovascular Disease.
Clinical pharmacology and therapeutics.
2018 07; 104(1):111-119. doi:
10.1002/cpt.1075
. [PMID: 29574792] - Ying Lu, Ying-Jun Zhu, Xiu-Ying Yue, Shao-Zheng Chen, Xiong Wang. [Effects of Gui Zhi Fu Ling Jiao Nang on Hemorheology and Expression of Phenotypic Proteins in Uterine Smooth Muscle Cells in Rats with An Intrauterine Device].
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae.
2018 Jun; 40(3):315-320. doi:
10.3881/j.issn.1000-503x.2018.03.003
. [PMID: 29978785] - Valerio De Stefano, Bianca Rocca, Alberto Tosetto, Denise Soldati, Giovanna Petrucci, Eloise Beggiato, Irene Bertozzi, Silvia Betti, Giuseppe Carli, Monica Carpenedo, Daniele Cattaneo, Viviana Cavalca, Alfredo Dragani, Elena Elli, Guido Finazzi, Alessandra Iurlo, Giuseppe Lanzarone, Laura Lissandrini, Francesca Palandri, Chiara Paoli, Alessandro Rambaldi, Paola Ranalli, Maria Luigia Randi, Alessandra Ricco, Elena Rossi, Marco Ruggeri, Giorgina Specchia, Andrea Timillero, Linda Turnu, Nicola Vianelli, Alessandro M Vannucchi, Francesco Rodeghiero, Carlo Patrono. The Aspirin Regimens in Essential Thrombocythemia (ARES) phase II randomized trial design: Implementation of the serum thromboxane B2 assay as an evaluation tool of different aspirin dosing regimens in the clinical setting.
Blood cancer journal.
2018 06; 8(6):49. doi:
10.1038/s41408-018-0078-3
. [PMID: 29880847] - Dong-Yue Sun, Xin-Ya Wang, Xiao-Ting Wang, Li Yan, Xiao-Feng Liu, Bo Pang, Hui Gao. [Comparison of integration processing technology of origin and traditional cutting processing technology of Moslae Herba for lung-Yang deficiency rats].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2018 Jun; 43(12):2537-2542. doi:
10.19540/j.cnki.cjcmm.20180322.001
. [PMID: 29950072] - Roberto Cangemi, Roberto Carnevale, Cristina Nocella, Camilla Calvieri, Vittoria Cammisotto, Marta Novo, Valentina Castellani, Alessandra D'Amico, Chiara Zerbinati, Lucia Stefanini, Francesco Violi. Glucocorticoids impair platelet thromboxane biosynthesis in community-acquired pneumonia.
Pharmacological research.
2018 05; 131(?):66-74. doi:
10.1016/j.phrs.2018.03.014
. [PMID: 29577968] - Naif M Alhawiti. Antiplatelets and profibrinolytic activity of Citrullus colocynthis in control and high-fat diet-induced obese rats: mechanisms of action.
Archives of physiology and biochemistry.
2018 May; 124(2):156-166. doi:
10.1080/13813455.2017.1369999
. [PMID: 28857634] - Wen-Li Cao, Jing Li. [Antithrombotic effects of recombinant hirudin in mice and its mechanism].
Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology.
2018 Apr; 34(4):371-374. doi:
10.12047/j.cjap.5664.2018.085
. [PMID: 30788948] - Taiki Hamabata, Tatsuro Nakamura, Sakura Masuko, Shingo Maeda, Takahisa Murata. Production of lipid mediators across different disease stages of dextran sodium sulfate-induced colitis in mice.
Journal of lipid research.
2018 04; 59(4):586-595. doi:
10.1194/jlr.m079095
. [PMID: 29414763] - Romain A Colas, Patricia R Souza, Mary E Walker, Maudrian Burton, Zbigniew Zasłona, Annie M Curtis, Raquel M Marques, Jesmond Dalli. Impaired Production and Diurnal Regulation of Vascular RvDn-3 DPA Increase Systemic Inflammation and Cardiovascular Disease.
Circulation research.
2018 03; 122(6):855-863. doi:
10.1161/circresaha.117.312472
. [PMID: 29437834] - Jane A Mitchell, Rebecca B Knowles, Nicholas S Kirkby, Daniel M Reed, Matthew L Edin, William E White, Melissa V Chan, Hilary Longhurst, Magdi M Yaqoob, Ginger L Milne, Darryl C Zeldin, Timothy D Warner. Kidney Transplantation in a Patient Lacking Cytosolic Phospholipase A2 Proves Renal Origins of Urinary PGI-M and TX-M.
Circulation research.
2018 02; 122(4):555-559. doi:
10.1161/circresaha.117.312144
. [PMID: 29298774] - Nina S McCarthy, Ciara Vangjeli, Praveen Surendran, Achim Treumann, Cathy Rooney, Emily Ho, Peter Sever, Simon Thom, Alun D Hughes, Patricia B Munroe, Philip Howard, Toby Johnson, Mark Caulfield, Denis C Shields, Eoin O'Brien, Desmond J Fitzgerald, Alice V Stanton. Genetic variants in PPARGC1B and CNTN4 are associated with thromboxane A2 formation and with cardiovascular event free survival in the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT).
Atherosclerosis.
2018 02; 269(?):42-49. doi:
10.1016/j.atherosclerosis.2017.12.013
. [PMID: 29258006] - N McLewee, T Archer, R Wills, A Mackin, J Thomason. Effects of aspirin dose escalation on platelet function and urinary thromboxane and prostacyclin levels in normal dogs.
Journal of veterinary pharmacology and therapeutics.
2018 Feb; 41(1):60-67. doi:
10.1111/jvp.12432
. [PMID: 28664658] - Yonghai Lu, Jinling Fang, Li Zou, Liang Cui, Xu Liang, Seng Gee Lim, Yock-Young Dan, Choon Nam Ong. Omega-6-derived oxylipin changes in serum of patients with hepatitis B virus-related liver diseases.
Metabolomics : Official journal of the Metabolomic Society.
2018 01; 14(3):26. doi:
10.1007/s11306-018-1326-z
. [PMID: 30830341] - Kay D Beharry, Charles L Cai, Gloria B Valencia, Douglas Lazzaro, Arwin M Valencia, Fabrizio Salomone, Jacob V Aranda. Human retinal endothelial cells and astrocytes cultured on 3-D scaffolds for ocular drug discovery and development.
Prostaglandins & other lipid mediators.
2018 01; 134(?):93-107. doi:
10.1016/j.prostaglandins.2017.09.005
. [PMID: 28923362] - Qi Zhang, Xiang Wang, Guifang Yan, Juan Lei, Yu Zhou, Lei Wu, Ting Wang, Xiao Zhang, Duyun Ye, Yongsheng Li. Anti- Versus Pro-Inflammatory Metabololipidome Upon Cupping Treatment.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology.
2018; 45(4):1377-1389. doi:
10.1159/000487563
. [PMID: 29462800] - Lei Pi, Di Che, Haifeng Long, Zhenzhen Fang, Jiawen Li, Shuyi Lin, Yunfeng Liu, Meiai Li, Lijuan Bao, Wenli Li, Yuan Zhang, Qiulian Deng, Techang Liu, Li Zhang, Xiaoqiong Gu. Immature platelets and antiplatelet therapy response to aspirin in Kawasaki disease.
Drug design, development and therapy.
2018; 12(?):1353-1362. doi:
10.2147/dddt.s163705
. [PMID: 29872260] - Nan Wang, Kimberly C Vendrov, Brian P Simmons, Robert N Schuck, George A Stouffer, Craig R Lee. Urinary 11-dehydro-thromboxane B2 levels are associated with vascular inflammation and prognosis in atherosclerotic cardiovascular disease.
Prostaglandins & other lipid mediators.
2018 01; 134(?):24-31. doi:
10.1016/j.prostaglandins.2017.11.003
. [PMID: 29155368] - Elena Gonzalo-Gil, Carmen García-Herrero, Oscar Toldos, Alicia Usategui, Gabriel Criado, Sonia Pérez-Yagüe, Domingo F Barber, Jose L Pablos, Maria Galindo. Microthrombotic Renal Vascular Lesions Are Associated to Increased Renal Inflammatory Infiltration in Murine Lupus Nephritis.
Frontiers in immunology.
2018; 9(?):1948. doi:
10.3389/fimmu.2018.01948
. [PMID: 30210500] - Paul A Gurbel, Kevin P Bliden, Junhong Zhu, Emanuel Troullos, Robert Centofanti, Sistine Jarvis, Palak Venkataraman, Udaya S Tantry. Thromboxane inhibition during concurrent therapy with low-dose aspirin and over-the-counter naproxen sodium.
Journal of thrombosis and thrombolysis.
2018 Jan; 45(1):18-26. doi:
10.1007/s11239-017-1593-y
. [PMID: 29198079] - Jingjing Zhou, Zehai Song, Mingshu Han, Baoxing Yu, Guanghui Lv, Na Han, Zhihui Liu, Jun Yin. Evaluation of the antithrombotic activity of Zhi-Xiong Capsules, a Traditional Chinese Medicinal formula, via the pathway of anti-coagulation, anti-platelet activation and anti-fibrinolysis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2018 Jan; 97(?):1622-1631. doi:
10.1016/j.biopha.2017.11.135
. [PMID: 29793324] - Yun-Xiu Hou, Shi-Wen Liu, Lian-Wen Wang, Shu-Hua Wu. Physiopathology of multiple organ dysfunctions in severely monocrotophos-poisoned rabbits.
Chemico-biological interactions.
2017 Dec; 278(?):9-14. doi:
10.1016/j.cbi.2017.08.016
. [PMID: 28864276] - Zu-Yue Deng, Wei-Guang Shan, Shen-Feng Wang, Meng-Mei Hu, Yan Chen. Effects of astaxanthin on blood coagulation, fibrinolysis and platelet aggregation in hyperlipidemic rats.
Pharmaceutical biology.
2017 Dec; 55(1):663-672. doi:
10.1080/13880209.2016.1261905
. [PMID: 27951728] - Nikolaos Kakouros, Tyler J Gluckman, John V Conte, Thomas S Kickler, Katherine Laws, Bruce A Barton, Jeffrey J Rade. Differential Impact of Serial Measurement of Nonplatelet Thromboxane Generation on Long-Term Outcome After Cardiac Surgery.
Journal of the American Heart Association.
2017 Nov; 6(11):. doi:
10.1161/jaha.117.007486
. [PMID: 29097390] - K Przyborowski, H Kassassir, M Wojewoda, K Kmiecik, B Sitek, K Siewiera, A Zakrzewska, A M Rudolf, R Kostogrys, C Watala, J A Zoladz, S Chlopicki. Effects of a single bout of strenuous exercise on platelet activation in female ApoE/LDLR-/- mice.
Platelets.
2017 Nov; 28(7):657-667. doi:
10.1080/09537104.2016.1254764
. [PMID: 28067100] - Naoaki Morihara, Atsuko Hino, Satomi Miki, Miyuki Takashima, Jun-Ichiro Suzuki. Aged garlic extract suppresses inflammation in apolipoprotein E-knockout mice.
Molecular nutrition & food research.
2017 10; 61(10):. doi:
10.1002/mnfr.201700308
. [PMID: 28726277] - Vincenzo Mollace, Giuseppe Rosano, Natalia Malara, Enzo Di Fabrizio, Cristiana Vitale, Marialaura Coluccio, Jessica Maiuolo, Ayesha Ali Wasti, Carolina Muscoli, Micaela Gliozzi, Rocco Mollace, Vincenzo Musolino, Cristina Carresi, Massimo Fini, Bruno Silvestrini. Aspirin wears smart.
European heart journal. Cardiovascular pharmacotherapy.
2017 10; 3(4):185-188. doi:
10.1093/ehjcvp/pvx017
. [PMID: 28505311] - Nikola Hadzi-Petrushev, Dine Mitrov, Vladimir Kostovski, Mitko Mladenov. The impact of vitamin C on the relationship among inflammation, lipid peroxidation and platelet activation during analgesic nephropathy in rats.
Journal of basic and clinical physiology and pharmacology.
2017 Sep; 28(5):473-481. doi:
10.1515/jbcpp-2016-0150
. [PMID: 28771433] - Daniele Pastori, Cristina Nocella, Alessio Farcomeni, Simona Bartimoccia, Maria Santulli, Fortunata Vasaturo, Roberto Carnevale, Danilo Menichelli, Francesco Violi, Pasquale Pignatelli. Relationship of PCSK9 and Urinary Thromboxane Excretion to Cardiovascular Events in Patients With Atrial Fibrillation.
Journal of the American College of Cardiology.
2017 Sep; 70(12):1455-1462. doi:
10.1016/j.jacc.2017.07.743
. [PMID: 28911508] - Mahim I Qureshi, Michele Greco, Panagiotis A Vorkas, Elaine Holmes, Alun H Davies. Application of Metabolic Profiling to Abdominal Aortic Aneurysm Research.
Journal of proteome research.
2017 07; 16(7):2325-2332. doi:
10.1021/acs.jproteome.6b00894
. [PMID: 28287739] - N O'Kennedy, L Crosbie, H-J Song, X Zhang, G Horgan, A K Duttaroy. A randomised controlled trial comparing a dietary antiplatelet, the water-soluble tomato extract Fruitflow, with 75 mg aspirin in healthy subjects.
European journal of clinical nutrition.
2017 06; 71(6):723-730. doi:
10.1038/ejcn.2016.222
. [PMID: 27876806] - Rachel C Drew, Cheryl A Blaha, Michael D Herr, Ruda Cui, Lawrence I Sinoway. Muscle mechanoreflex activation via passive calf stretch causes renal vasoconstriction in healthy humans.
American journal of physiology. Regulatory, integrative and comparative physiology.
2017 06; 312(6):R956-R964. doi:
10.1152/ajpregu.00322.2016
. [PMID: 28381456] - Anupama Vasudevan, Teodoro Bottiglieri, Kristen M Tecson, Mohanakrishnan Sathyamoorthy, Jeffrey M Schussler, Carlos E Velasco, Luis R Lopez, Caren Swift, Margarita Peterson, Jeanna Bennett-Firmin, Raphael Schiffmann, Peter A McCullough. Residual thromboxane activity and oxidative stress: influence on mortality in patients with stable coronary artery disease.
Coronary artery disease.
2017 Jun; 28(4):287-293. doi:
10.1097/mca.0000000000000461
. [PMID: 28005558] - D T Robinson, H L Palac, V Baillif, E Van Goethem, M Dubourdeau, L Van Horn, C R Martin. Long chain fatty acids and related pro-inflammatory, specialized pro-resolving lipid mediators and their intermediates in preterm human milk during the first month of lactation.
Prostaglandins, leukotrienes, and essential fatty acids.
2017 Jun; 121(?):1-6. doi:
10.1016/j.plefa.2017.05.003
. [PMID: 28651692] - Pingyao Xie, Yong Zhang, Xuebiao Wang, Jinfeng Wei, Wenyi Kang. Antithrombotic effect and mechanism of Rubus spp. Blackberry.
Food & function.
2017 May; 8(5):2000-2012. doi:
10.1039/c6fo01717g
. [PMID: 28485425] - J S Paikin, J Hirsh, J S Ginsberg, J I Weitz, N C Chan, R P Whitlock, G Pare, J W Eikelboom. Once versus twice daily aspirin after coronary bypass surgery: a randomized trial.
Journal of thrombosis and haemostasis : JTH.
2017 05; 15(5):889-896. doi:
10.1111/jth.13667
. [PMID: 28267249] - Peter A McCullough, Anupama Vasudevan, Mohanakrishnan Sathyamoorthy, Jeffrey M Schussler, Carlos E Velasco, Luis R Lopez, Caren Swift, Margarita Peterson, Jenna Bennett-Firmin, Raphael Schiffmann, Teodoro Bottiglieri. Urinary 11-Dehydro-Thromboxane B2 and Mortality in Patients With Stable Coronary Artery Disease.
The American journal of cardiology.
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