4-Chlorophenoxyacetic acid (BioDeep_00000002118)

 

Secondary id: BioDeep_00000408788

human metabolite blood metabolite


代谢物信息卡片


4-Chlorophenoxyacetic acid, potassium salt

化学式: C8H7ClO3 (186.0084)
中文名称: 4-氯苯氧乙酸
谱图信息: 最多检出来源 Homo sapiens(blood) 41.92%

分子结构信息

SMILES: C1=CC(=CC=C1OCC(=O)O)Cl
InChI: InChI=1S/C8H7ClO3/c9-6-1-3-7(4-2-6)12-5-8(10)11/h1-4H,5H2,(H,10,11)

描述信息

CONFIDENCE standard compound; INTERNAL_ID 1191; DATASET 20200303_ENTACT_RP_MIX499; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3757; ORIGINAL_PRECURSOR_SCAN_NO 3752
CONFIDENCE standard compound; INTERNAL_ID 1191; DATASET 20200303_ENTACT_RP_MIX507; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3829; ORIGINAL_PRECURSOR_SCAN_NO 3825
CONFIDENCE standard compound; INTERNAL_ID 1191; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4159; ORIGINAL_PRECURSOR_SCAN_NO 4154
CONFIDENCE standard compound; INTERNAL_ID 1191; DATASET 20200303_ENTACT_RP_MIX499; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 3737; ORIGINAL_PRECURSOR_SCAN_NO 3736
CONFIDENCE standard compound; INTERNAL_ID 1191; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4074; ORIGINAL_PRECURSOR_SCAN_NO 4072
CONFIDENCE standard compound; INTERNAL_ID 1191; DATASET 20200303_ENTACT_RP_MIX505; DATA_PROCESSING MERGING RMBmix ver. 0.2.7; DATA_PROCESSING PRESCREENING Shinyscreen ver. 0.8.0; ORIGINAL_ACQUISITION_NO 4080; ORIGINAL_PRECURSOR_SCAN_NO 4076
KEIO_ID C151

同义名列表

17 个代谢物同义名

4-Chlorophenoxyacetic acid, potassium salt; 4-Chlorophenoxyacetic acid, ammonium salt; 4-Chlorophenoxyacetic acid, sodium salt; 2-(4-chlorophenoxy)acetic acid; Para-chlorophenoxyacetic acid; (p-Chlorophenoxy)acetic acid; 4-CHLOROPHENOXYACETIC ACID; P-Chlorophenoxyacetic acid; Para-chlorophenoxyacetate; 4-Chlorphenoxyessigsaeure; (p-Chlorophenoxy)acetate; (4-Chlorophenoxy)acetate; p-Chlorophenoxyacetate; 4-Chlorophenoxyacetate; sure-set; 4-CPA; 4-Chlorophenoxyacetate



数据库引用编号

24 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 7 AHR, CAT, FST, G6PD, GADD45G, PPM1G, PTP4A2
Peripheral membrane protein 2 CRAT, G6PD
Nucleus 6 AHR, FST, GADD45G, PPARA, PPM1G, PTP4A2
cytosol 8 AHR, CAT, CLC, CRAT, G6PD, GSR, LEP, PTP4A2
dendrite 1 C4A
nucleoplasm 4 AHR, CD2, PPARA, PPM1G
Cell membrane 2 CD2, NPHS1
Lipid-anchor 1 PPM1G
Cell projection, axon 1 C4A
Cytoplasmic granule 1 CLC
Multi-pass membrane protein 1 SLC9C1
Synapse 1 C4A
cell surface 1 CD2
Golgi apparatus 3 ATRN, CD2, NPY
mitochondrial inner membrane 1 CRAT
neuronal cell body 1 C4A
Cytoplasm, cytosol 2 CLC, G6PD
Lysosome 1 CTSV
plasma membrane 6 ATRN, C4A, CD2, NPHS1, PTP4A2, SLC9C1
Membrane 4 CAT, G6PD, PPM1G, SLC9C1
axon 1 C4A
extracellular exosome 6 ATRN, C4A, CAT, G6PD, GSR, NPHS1
endoplasmic reticulum 1 CRAT
extracellular space 7 ATRN, C4A, CLC, CTSV, FST, LEP, NPY
lysosomal lumen 1 CTSV
mitochondrion 3 CAT, CRAT, GSR
protein-containing complex 3 AHR, CAT, CD2
intracellular membrane-bounded organelle 2 CAT, G6PD
Single-pass type I membrane protein 3 ATRN, CD2, NPHS1
Secreted 5 C4A, CLC, LEP, NPY, PRB1
extracellular region 9 C4A, CAT, CD2, CLC, CTSV, FST, LEP, NPY, PRB1
cytoplasmic side of plasma membrane 2 CD2, G6PD
[Isoform 2]: Secreted 1 ATRN
mitochondrial matrix 2 CAT, GSR
transcription regulator complex 1 AHR
centriolar satellite 1 G6PD
motile cilium 1 SLC9C1
external side of plasma membrane 2 CD2, GSR
slit diaphragm 1 NPHS1
Early endosome 1 PTP4A2
cell-cell junction 2 CD2, NPHS1
Mitochondrion inner membrane 1 CRAT
Matrix side 1 CRAT
focal adhesion 2 CAT, NPHS1
GABA-ergic synapse 1 NPY
Peroxisome 2 CAT, CRAT
Peroxisome matrix 1 CAT
peroxisomal matrix 2 CAT, CRAT
peroxisomal membrane 1 CAT
collagen-containing extracellular matrix 1 CLC
chromatin 2 AHR, PPARA
cell projection 1 NPHS1
[Isoform 1]: Mitochondrion 1 CRAT
blood microparticle 1 C4A
[Isoform 3]: Secreted 1 ATRN
Cell projection, cilium, flagellum membrane 1 SLC9C1
aryl hydrocarbon receptor complex 1 AHR
Cell projection, dendrite 1 C4A
ficolin-1-rich granule lumen 1 CAT
secretory granule lumen 1 CAT
endoplasmic reticulum lumen 1 C4A
neuronal dense core vesicle 1 NPY
[Isoform 1]: Cell membrane 1 ATRN
CRLF-CLCF1 complex 1 CLC
Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle 1 NPY
catalase complex 1 CAT
CNTFR-CLCF1 complex 1 CLC
nuclear aryl hydrocarbon receptor complex 1 AHR
cytosolic aryl hydrocarbon receptor complex 1 AHR
[Isoform 2]: Peroxisome 1 CRAT


文献列表

  • Junjun Feng, Haiyun Jiang, Jing Wang, Zhengyi Jing, Fan Zhang, Tianyu Tan, Feng He, Lihua Jiang, Haiqin Li, Shimin Chang, Tengfei Li. [Simultaneous determination of 40 plant growth regulators, fungicides, insecticides, and antibiotics in bean sprouts by QuEChERS-high performance liquid chromatography-tandem mass spectrometry]. Se pu = Chinese journal of chromatography. 2022 Sep; 40(9):843-853. doi: 10.3724/sp.j.1123.2021.12028. [PMID: 36156631]
  • Zhenhua Liu, Yan Wang, Wenjiang Pu, Haifeng Zhu, Jinjun Liang, Jiang Wu, Liang Hong, Pingyin Guan, Jianfang Hu. 4-CPA (4-Chlorophenoxyacetic Acid) Induces the Formation and Development of Defective 'Fenghou' (Vitis vinifera × V. labrusca) Grape Seeds. Biomolecules. 2021 03; 11(4):. doi: 10.3390/biom11040515. [PMID: 33808413]
  • Qixun Nian, Lianfeng Ai, Dongmei Li, Xuelei Chen, Lei Zhang, Manman Wang, Xuesheng Wang. Rapid monitoring of plant growth regulators in bean sprouts via automated on-line polymeric monolith solid-phase extraction coupled with liquid chromatography tandem mass spectrometry. Analytical and bioanalytical chemistry. 2018 Nov; 410(27):7239-7247. doi: 10.1007/s00216-018-1334-x. [PMID: 30151683]
  • Wenxin Yuan, Zhiping Liu, Ping Liu, Rong Zhao, Guohua Wu, Sai Fan, Yang Zhou. [Determination of 4 kinds of plant growth regulator in bean sprout by solid phase extraction column coupled with ultra-high performance liquid chromatography]. Wei sheng yan jiu = Journal of hygiene research. 2017 Sep; 46(5):783-812. doi: . [PMID: 29903308]
  • Nishikant Wase, Boqiang Tu, James W Allen, Paul N Black, Concetta C DiRusso. Identification and Metabolite Profiling of Chemical Activators of Lipid Accumulation in Green Algae. Plant physiology. 2017 Aug; 174(4):2146-2165. doi: 10.1104/pp.17.00433. [PMID: 28652262]
  • Yehong Han, Chunliu Yang, Yang Zhou, Dandan Han, Hongyuan Yan. Ionic Liquid-Hybrid Molecularly Imprinted Material-Filter Solid-Phase Extraction Coupled with HPLC for Determination of 6-Benzyladenine and 4-Chlorophenoxyacetic Acid in Bean Sprouts. Journal of agricultural and food chemistry. 2017 Mar; 65(8):1750-1757. doi: 10.1021/acs.jafc.6b03922. [PMID: 28147482]
  • Shilei Ji, Li Qi, Nan Li, Minglin Wang. Preparation of amino acid-based polymer functionalized magnetic nanoparticles as adsorbents for analysis of plant growth regulators in bean sprouts. Talanta. 2016 Sep; 158(?):229-234. doi: 10.1016/j.talanta.2016.05.056. [PMID: 27343600]
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  • Hehe Huang, Jin Zhang, Dunming Xu, Yu Zhou, Jia Luo, Meiling Li, Shubin Chen, Lianzhu Wang. [Determination of 21 plant growth regulator residues in fruits by QuEChERS-high performance liquid chromatography-tandem mass spectrometry]. Se pu = Chinese journal of chromatography. 2014 Jul; 32(7):707-16. doi: 10.3724/sp.j.1123.2014.03003. [PMID: 25255562]
  • Hanbing Xie, Mingying Zhou, Haifeng Zhao, Yigang Wang, Wanfeng Jiang, Shan Zhao. [Determination of three exogenous plant hormone residues in bean sprout by high performance liquid chromatography-quadrupole-time of flight mass spectrometry]. Se pu = Chinese journal of chromatography. 2014 May; 32(5):493-8. doi: 10.3724/sp.j.1123.2013.12029. [PMID: 25185309]
  • Vasantharaju S Gowdra, Jayesh Mudgal, Punit Bansal, Pawan G Nayak, Seethappa A Manohara Reddy, Gautham G Shenoy, Manna Valiathan, Mallikarjuna R Chamallamudi, Gopalan K Nampurath. Synthesis, characterization, and preclinical evaluation of new thiazolidin-4-ones substituted with p-chlorophenoxy acetic acid and clofibric acid against insulin resistance and metabolic disorder. BioMed research international. 2014; 2014(?):620434. doi: 10.1155/2014/620434. [PMID: 24995315]
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  • Emeline L Maillet, Robert F Margolskee, Bedrich Mosinger. Phenoxy herbicides and fibrates potently inhibit the human chemosensory receptor subunit T1R3. Journal of medicinal chemistry. 2009 Nov; 52(21):6931-5. doi: 10.1021/jm900823s. [PMID: 19817384]
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