Ciprofloxacin (BioDeep_00000001534)

 

Secondary id: BioDeep_00000397461

human metabolite blood metabolite PANOMIX_OTCML-2023 Chemicals and Drugs natural product


代谢物信息卡片


1-Cyclopropyl-6-fluoro-7-(4-methyl-piperazin-1-yl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid

化学式: C17H18FN3O3 (331.1332)
中文名称: 环丙沙星
谱图信息: 最多检出来源 Homo sapiens(otcml) 9.81%

分子结构信息

SMILES: C(C1)C1N(C=C(C-2=O)C(=O)O)-c(cc(c3F)N(CCN4)CC4)c2c3
InChI: InChI=1S/C17H18FN3O3/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24/h7-10,19H,1-6H2,(H,23,24)

描述信息

Ciprofloxacin is only found in individuals that have used or taken this drug. It is a broad-spectrum antimicrobial carboxyfluoroquinoline.The bactericidal action of ciprofloxacin results from inhibition of the enzymes topoisomerase II (DNA gyrase) and topoisomerase IV, which are required for bacterial DNA replication, transcription, repair, strand supercoiling repair, and recombination.
J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01M - Quinolone antibacterials > J01MA - Fluoroquinolones
D004791 - Enzyme Inhibitors > D065607 - Cytochrome P-450 Enzyme Inhibitors > D065609 - Cytochrome P-450 CYP1A2 Inhibitors
S - Sensory organs > S03 - Ophthalmological and otological preparations > S03A - Antiinfectives > S03AA - Antiinfectives
D000970 - Antineoplastic Agents > D059003 - Topoisomerase Inhibitors > D059005 - Topoisomerase II Inhibitors
S - Sensory organs > S01 - Ophthalmologicals > S01A - Antiinfectives > S01AE - Fluoroquinolones
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D024841 - Fluoroquinolones
C254 - Anti-Infective Agent > C52588 - Antibacterial Agent > C280 - Antitubercular Agent
S - Sensory organs > S02 - Otologicals > S02A - Antiinfectives > S02AA - Antiinfectives
C254 - Anti-Infective Agent > C258 - Antibiotic > C795 - Quinolone Antibiotic
CONFIDENCE standard compound; EAWAG_UCHEM_ID 276
KEIO_ID C133; [MS3] KO008906
KEIO_ID C133; [MS2] KO008905
KEIO_ID C133
Ciprofloxacin (Bay-09867) is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin has anti-proliferative activity and induces apoptosis. Ciprofloxacin is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity[1][2][3][4].
Ciprofloxacin (Bay-09867) is a potent, orally active topoisomerase IV inhibitor. Ciprofloxacin induces mitochondrial DNA and nuclear DNA damage and lead to mitochondrial dysfunction, ROS production. Ciprofloxacin has anti-proliferative activity and induces apoptosis. Ciprofloxacin is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity[1][2][3][4].

同义名列表

33 个代谢物同义名

1-Cyclopropyl-6-fluoro-7-(4-methyl-piperazin-1-yl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid; 1-Cyclopropyl-6-fluoro-7-(4-methyl-piperazin-1-yl)-4-oxo-1,4-dihydro-quinoline-3-carboxylate; 1-Cyclopropyl-6-fluoro-7-hexahydro-1-pyrazinyl-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid; 1-Cyclopropyl-6-fluoro-7-hexahydro-1-pyrazinyl-4-oxo-1,4-dihydro-3-quinolinecarboxylate; 1-Cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid; 1-Cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-quinoline-3-carboxylic acid; 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid; 1-CYCLOPROPYL-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydroquinoline-3-carboxylIC ACID; 1-Cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylate; 1-Cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-quinoline-3-carboxylate; 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylate; 1-CYCLOPROPYL-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydroquinoline-3-carboxylate; 1-Cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid; 1-Cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylate; Monohydrochloride monohydrate, ciprofloxacin; Monohydrate, ciprofloxacin monohydrochloride; Ciprofloxacin monohydrochloride monohydrate; Anhydrous, ciprofloxacin hydrochloride; Hydrochloride anhydrous, ciprofloxacin; Ciprofloxacin hydrochloride anhydrous; Ciprofloxacin monohydrochloride; Hydrochloride, ciprofloxacin; Ciprofloxacin Hydrochloride; Ciprofloxacinum; Ciprofloxacino; Ciprofloxacina; Ciprofloxacine; ciprofloxacin; Ciprinol; Cipro; CPFX; Bay-09867; Ciprofloxacin



数据库引用编号

42 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

6 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 4 ABCB1, ALB, CYP3A4, MRTFA
Peripheral membrane protein 2 CYP1B1, CYP27A1
Endoplasmic reticulum membrane 3 CYP1A2, CYP1B1, CYP3A4
Mitochondrion membrane 2 ABCG2, CYP27A1
Nucleus 3 ALB, KLK3, MRTFA
cytosol 4 ALB, ATP12A, LIPE, MRTFA
dendrite 1 PCDH8
mitochondrial membrane 1 ABCG2
centrosome 1 ALB
nucleoplasm 2 ABCG2, MRTFA
Cell membrane 6 ABCB1, ABCG2, LIPE, PCDH8, RECK, TNF
Multi-pass membrane protein 3 ABCB1, ABCG2, ATP12A
cell surface 3 ABCB1, TNF, TNR
glutamatergic synapse 3 MRTFA, PCDH8, TNR
Golgi apparatus 2 ALB, ATRN
mitochondrial inner membrane 1 CYP27A1
neuronal cell body 1 TNF
postsynapse 1 MRTFA
presynaptic membrane 1 PCDH8
Cytoplasm, cytosol 1 LIPE
Presynapse 1 MRTFA
plasma membrane 8 ABCB1, ABCG2, ATP12A, ATRN, KLK3, PCDH8, RECK, TNF
Membrane 6 ABCB1, ABCG2, CYP1B1, CYP3A4, LIPE, RECK
apical plasma membrane 3 ABCB1, ABCG2, ATP12A
basolateral plasma membrane 1 ATP12A
caveola 1 LIPE
extracellular exosome 4 ABCB1, ALB, ATRN, KLK3
endoplasmic reticulum 1 ALB
extracellular space 9 ALB, ATRN, CRP, CSF3, CXCL8, IL2, KLK3, TNF, TNR
lysosomal lumen 1 CSF3
Schaffer collateral - CA1 synapse 2 PCDH8, TNR
mitochondrion 2 CYP1B1, CYP27A1
protein-containing complex 2 ALB, KLK3
intracellular membrane-bounded organelle 3 CYP1A2, CYP1B1, CYP3A4
Microsome membrane 3 CYP1A2, CYP1B1, CYP3A4
Single-pass type I membrane protein 2 ATRN, PCDH8
Secreted 5 ALB, CRP, CSF3, CXCL8, IL2
extracellular region 9 ALB, CRP, CSF3, CXCL8, IL2, KLK3, RECK, TNF, TNR
[Isoform 2]: Secreted 1 ATRN
mitochondrial matrix 1 CYP27A1
anchoring junction 1 ALB
external side of plasma membrane 1 TNF
Secreted, extracellular space, extracellular matrix 1 TNR
actin cytoskeleton 1 ATP12A
Wnt signalosome 1 RECK
recycling endosome 1 TNF
Single-pass type II membrane protein 1 TNF
postsynaptic membrane 1 PCDH8
Apical cell membrane 3 ABCB1, ABCG2, ATP12A
Mitochondrion inner membrane 1 CYP27A1
Membrane raft 3 ABCG2, TNF, TNR
collagen-containing extracellular matrix 1 TNR
secretory granule 1 KLK3
ciliary basal body 1 ALB
phagocytic cup 1 TNF
centriole 1 ALB
brush border membrane 1 ABCG2
spindle pole 1 ALB
blood microparticle 1 ALB
Lipid-anchor, GPI-anchor 1 RECK
[Isoform 3]: Secreted 1 ATRN
Lipid droplet 1 LIPE
Membrane, caveola 1 LIPE
Cell projection, dendrite 1 PCDH8
side of membrane 1 RECK
endoplasmic reticulum lumen 1 ALB
platelet alpha granule lumen 1 ALB
perineuronal net 1 TNR
external side of apical plasma membrane 2 ABCB1, ABCG2
[Isoform 1]: Cell membrane 1 ATRN
endocytic vesicle lumen 1 CSF3
[Tumor necrosis factor, soluble form]: Secreted 1 TNF
potassium:proton exchanging ATPase complex 1 ATP12A
tenascin complex 1 TNR
ciliary transition fiber 1 ALB
[C-domain 2]: Secreted 1 TNF
[Tumor necrosis factor, membrane form]: Membrane 1 TNF
[C-domain 1]: Secreted 1 TNF


文献列表

  • Elif Yakamercan, Ahmet Aygün, Halis Simsek. Antibiotic ciprofloxacin removal from aqueous solutions by electrochemically activated persulfate process: Optimization, degradation pathways, and toxicology assessment. Journal of environmental sciences (China). 2024 Sep; 143(?):85-98. doi: 10.1016/j.jes.2023.08.013. [PMID: 38644026]
  • Pei Fan, Haihao Yu, Tian Lv, Huiyuan Wang, Dexiang Li, Chao Tong, Zhonghua Wu, Dan Yu, Chunhua Liu. Alien emergent aquatic plants develop better ciprofloxacin tolerance and metabolic capacity than one native submerged species. The Science of the total environment. 2024 Jul; 932(?):173030. doi: 10.1016/j.scitotenv.2024.173030. [PMID: 38719043]
  • Zuhier Alakayleh, Faisal Al-Akayleh, Mayyas Al-Remawi, Waseem Mahyoob, Husam A Abu Hajar, Muayad Esaifan, Reyad Shawabkeh. Utilizing olive leaves biomass as an efficient adsorbent for ciprofloxacin removal: characterization, isotherm, kinetic, and thermodynamic analysis. Environmental monitoring and assessment. 2024 May; 196(6):562. doi: 10.1007/s10661-024-12712-0. [PMID: 38769235]
  • Zirwa Fayyaz, Muhammad Akhyar Farrukh, Anwar Ul-Hamid, Kok-Keong Chong. Elucidating the structural, catalytic, and antibacterial traits of Ficus carica and Azadirachta indica leaf extract-mediated synthesis of the Ag/CuO/rGO nanocomposite. Microscopy research and technique. 2024 May; 87(5):957-976. doi: 10.1002/jemt.24487. [PMID: 38174385]
  • Giedrė Kacienė, Austra Dikšaitytė, Irena Januškaitienė, Diana Miškelytė, Gintarė Sujetovienė, Renata Dagiliūtė, Jūratė Žaltauskaitė. Veterinary antibiotics differ in phytotoxicity on oilseed rape grown over a wide range of concentrations. Chemosphere. 2024 May; 356(?):141977. doi: 10.1016/j.chemosphere.2024.141977. [PMID: 38608779]
  • Klaudia Stando, Michał Grzybowski, Anna Byczek-Wyrostek, Sylwia Bajkacz. Efficiency of phytoremediation and identification of biotransformation pathways of fluoroquinolones in the aquatic environment. International journal of phytoremediation. 2024 May; 26(7):1027-1037. doi: 10.1080/15226514.2023.2288898. [PMID: 38069676]
  • Xiaolian Wu, Chenze Jin, Gengying Du, Jianan Wang, Jiayi Su, Rongxuan Li. Urea promoted soil microbial community and reduced the residual ciprofloxacin in soil and its uptake by Chinese flowering cabbage. Environmental science and pollution research international. 2024 Apr; 31(20):30137-30148. doi: 10.1007/s11356-024-33213-0. [PMID: 38602632]
  • M A Hossain, A U Ahmed, M M S Shahabuddin, K E Zannat, S M M Tanzim, A Afrin, S Nahar, M Aktar, R N Shimu, S Sultana, M Afrin, S Jahan. Antibacterial Activities of Methanolic Seeds Extract of Black pepper (Piper nigrum L.) against Gram Positive Staphylococcus aureus & Gram-Negative Escherichia coli. Mymensingh medical journal : MMJ. 2024 Apr; 33(2):350-355. doi: ". [PMID: 38557509]
  • Junnan Li, Luhua You, Zichen Xu, Karina Yew-Hoong Gin, Yiliang He. Nano-scale and micron-scale plastics amplify the bioaccumulation of benzophenone-3 and ciprofloxacin, as well as their co-exposure effect on disturbing the antioxidant defense system in mussels, Perna viridis. Environmental pollution (Barking, Essex : 1987). 2024 Apr; 346(?):123547. doi: 10.1016/j.envpol.2024.123547. [PMID: 38387549]
  • Yu-Hong Huang, Yu-Jie Yang, Jie-Yu Li, Huixiong Lü, Hai-Ming Zhao, Lei Xiang, Hui Li, Ce-Hui Mo, Yan-Wen Li, Quan-Ying Cai, Qing X Li. Root-associated bacteria strengthen their community stability against disturbance of antibiotics on structure and functions. Journal of hazardous materials. 2024 Mar; 465(?):133317. doi: 10.1016/j.jhazmat.2023.133317. [PMID: 38218031]
  • P Sirajunnisa, S Sreelakshmi, G S Sailaja. Lawsonia inermis-organically modified chitosan intercalated bentonite clay: A multifunctional nanotheranostic system for controlled drug delivery, sensing and cellular imaging. International journal of biological macromolecules. 2024 Mar; 262(Pt 2):130209. doi: 10.1016/j.ijbiomac.2024.130209. [PMID: 38365155]
  • Hussan Ibne Shoukani, Sobia Nisa, Yamin Bibi, Muhammad Zia, Anila Sajjad, Afsheen Ishfaq, Hussain Ali. Ciprofloxacin loaded PEG coated ZnO nanoparticles with enhanced antibacterial and wound healing effects. Scientific reports. 2024 02; 14(1):4689. doi: 10.1038/s41598-024-55306-z. [PMID: 38409460]
  • Érika M L Sousa, Marta Otero, María V Gil, Paula Ferreira, Valdemar I Esteves, Vânia Calisto. Evaluation of different functionalization methodologies for improving the removal of three target antibiotics from wastewater by a brewery waste activated carbon. The Science of the total environment. 2024 Feb; 912(?):169437. doi: 10.1016/j.scitotenv.2023.169437. [PMID: 38128671]
  • Hai-Ming Zhao, He-Biao Huang, Zhen-Xuan Zhan, Yao-Yao Ye, Ji-Liang Cheng, Lei Xiang, Yan-Wen Li, Quan-Ying Cai, Yunchang Xie, Ce-Hui Mo. Insights into the molecular network underlying phytotoxicity and phytoaccumulation of ciprofloxacin. The Science of the total environment. 2024 Feb; 912(?):169392. doi: 10.1016/j.scitotenv.2023.169392. [PMID: 38104812]
  • Mahmood Yousefi, Mahdi Farzadkia, Amir Hossein Mahvi, Majid Kermani, Mitra Gholami, Ali Esrafili. Photocatalytic degradation of ciprofloxacin using a novel carbohydrate-based nanocomposite from aqueous solutions. Chemosphere. 2024 Feb; 349(?):140972. doi: 10.1016/j.chemosphere.2023.140972. [PMID: 38114023]
  • Gisele Canan-Rochenbach, Marco A B Barreiros, André O S Lima, Pascale Bauda, Eric Sanches-Simões, Wendell Pimentel-Almeida, Rafael Ariente-Neto, Cleder A Somensi, Tito C M Almeida, Rogério Corrêa, Claudemir M Radetski. Characterization of bacterial resistance in treated hospital wastewater. Environmental technology. 2024 Jan; 45(1):120-128. doi: 10.1080/09593330.2022.2100282. [PMID: 35802062]
  • Luu Quynh Huong, Thomas Chisnall, John D Rodgers, Shaun A Cawthraw, Roderick M Card. Prevalence, antibiotic resistance, and genomic characterisation of Campylobacter spp. in retail chicken in Hanoi, Vietnam. Microbial genomics. 2024 Jan; 10(1):. doi: 10.1099/mgen.0.001190. [PMID: 38294872]
  • Mengnan Shen, Yi Hu, Ke Zhao, Zhi Qu, Chen Lyu, Binshuo Liu, Ming Li, Xiaodan Bu, Chenyang Li, Shuang Zhong, Jie Cheng. Effects of dissolved organic matter, pH and nutrient on ciprofloxacin bioaccumulation and toxicity in duckweed. Aquatic toxicology (Amsterdam, Netherlands). 2024 Jan; 266(?):106775. doi: 10.1016/j.aquatox.2023.106775. [PMID: 38043483]
  • Chandra Kant Singh, Kushneet Kaur Sodhi, Dileep Kumar Singh. Understanding the bacterial community structure associated with the Eichhornia crassipes rootzone. Molecular biology reports. 2023 Dec; 51(1):35. doi: 10.1007/s11033-023-08979-0. [PMID: 38157124]
  • Marina Ika Irianti, Jean-Paul Vincken, Sarah van Dinteren, Ellen Ter Beest, Klaas Martinus Pos, Carla Araya-Cloutier. Prenylated isoflavonoids from Fabaceae against the NorA efflux pump in Staphylococcus aureus. Scientific reports. 2023 12; 13(1):22548. doi: 10.1038/s41598-023-48992-8. [PMID: 38110428]
  • Gamze Ersan, Alexsandro J Dos Santos, Marcos R V Lanza, François Perreault, Sergi Garcia-Segura. Enhancing the selective ciprofloxacin adsorption in urine matrices through the metal-doping of carbon sorbents. Journal of environmental management. 2023 Dec; 348(?):119298. doi: 10.1016/j.jenvman.2023.119298. [PMID: 37839202]
  • Yong Xiao, Jiahong He, Jibin An, Taiping Xie, Junjie Lin. Highly efficient activation of peroxymonosulfate by ZIF-67 anchored cotton derived for ciprofloxacin degradation. Environmental research. 2023 Dec; 244(?):117863. doi: 10.1016/j.envres.2023.117863. [PMID: 38070857]
  • Adeola Olowofolahan, Omowumi Fatunsin, Olufunso Olorunsogo. Modulatory effect of ciprofloxacin, a broad spectrum antibacterial drug, on mPT pore using rat model with estradiol benzoate-induced endometrial hyperplasia. Naunyn-Schmiedeberg's archives of pharmacology. 2023 Nov; ?(?):. doi: 10.1007/s00210-023-02824-8. [PMID: 37943297]
  • Iñaki Deza-Cruz, María J Vilar, Martina Velasova, Manal AbuOun, Muna F Anjum, Richard P Smith. Antimicrobial resistance of Escherichia coli in the UK: comparison of single vs. pooled samples from healthy pigs. Letters in applied microbiology. 2023 Nov; ?(?):. doi: 10.1093/lambio/ovad123. [PMID: 37942558]
  • Jian-Fang Yan, Lei Xiang, Bi-Ying Zhang, Can Tang, You-Qun Xie, Yan-Wen Li, Nai-Xian Feng, Bai-Lin Liu, Hui Li, Quan-Ying Cai, Qing X Li, Hai-Ming Zhao, Ce-Hui Mo. Mechanism and Association between Microbial Nitrogen Transformation in Rhizosphere and Accumulation of Ciprofloxacin in Choysum (Brassica parachinensis). Environmental science & technology. 2023 10; 57(42):16053-16064. doi: 10.1021/acs.est.3c04709. [PMID: 37824517]
  • Genilson Silva de Jesus, Danielle Silva Trentin, Thayná Fernandes Barros, Alda Maria Teixeira Ferreira, Bruna Castro de Barros, Patrícia de Oliveira Figueiredo, Fernanda Rodrigues Garcez, Érica Luiz Dos Santos, Ana Camila Micheletti, Nidia Cristiane Yoshida. Medicinal plant Miconia albicans synergizes with ampicillin and ciprofloxacin against multi-drug resistant Acinetobacter baumannii and Staphylococcus aureus. BMC complementary medicine and therapies. 2023 Oct; 23(1):374. doi: 10.1186/s12906-023-04147-w. [PMID: 37872494]
  • Tanongsak Sassa-Deepaeng, Wachira Yodthong, Nattakanwadee Khumpirapang, Songyot Anuchapreeda, Siriporn Okonogi. Effects of plant-based copper nanoparticles on the elimination of ciprofloxacin. Drug discoveries & therapeutics. 2023 Oct; ?(?):. doi: 10.5582/ddt.2023.01057. [PMID: 37839876]
  • Amr M Shehabeldine, Abdulaziz A Al-Askar, Hamada AbdElgawad, Fatouh A Hagras, Amr A Ramadan, Mohamed R Kamel, Mohamed A Ahmed, Kareem H Atia, Amr H Hashem. Wound Dressing Scaffold with High Anti-biofilm Performance Based on Ciprofloxacin-Loaded Chitosan-Hydrolyzed Starch Nanocomposite: In Vitro and In Vivo Study. Applied biochemistry and biotechnology. 2023 Oct; 195(10):6421-6439. doi: 10.1007/s12010-023-04665-w. [PMID: 37450215]
  • Tennyson Mathai, Tathagata Pal, Nayan Prakash, Soumyo Mukherji. Portable biosensor for the detection of Enrofloxacin and Ciprofloxacin antibiotic residues in food, body fluids, environmental and wastewater samples. Biosensors & bioelectronics. 2023 Oct; 237(?):115478. doi: 10.1016/j.bios.2023.115478. [PMID: 37356410]
  • K E Zannat, S M Tanzim, A Afrin, N Akter, M S Mostaqim, J B Joynal, M Ferdausee, B C Saha, N H Nira. Antibacterial Effects of Methanol Henna (Lawsone inermis) Leaf Extracts against Two Food Borne Infection Causing Pathogens: Gram-Positive Staphylococcus aureus and Gram Negative Klebsiella pneumoniae. Mymensingh medical journal : MMJ. 2023 Oct; 32(4):1009-1014. doi: . [PMID: 37777894]
  • Florence Nantaba, John Wasswa, Henrik Kylin, Hindrik Bouwman, Wolf-Ulrich Palm, Klaus Kümmerer. Spatial trends and ecotoxic risk assessment of selected pharmaceuticals in sediments from Lake Victoria, Uganda, East Africa. The Science of the total environment. 2023 Sep; 906(?):167348. doi: 10.1016/j.scitotenv.2023.167348. [PMID: 37769731]
  • Muhammad Talha Usmani, Muhammad Harris Shoaib, Fahad Siddiqui, Farrukh Rafiq Ahmed, Rabia Ismail Yousuf, Muhammad Talha Saleem. Formulation development, in vivo bioequivalence and pediatric PBPK modeling studies of taste-masked ciprofloxacin chewable tablets. Scientific reports. 2023 09; 13(1):16070. doi: 10.1038/s41598-023-43423-0. [PMID: 37752265]
  • Wenjie Cai, Mingqi Lu, Weijun Dai. Novel antibiotic susceptibility of an RNA polymerase α-subunit mutant in Pseudomonas aeruginosa. The Journal of antimicrobial chemotherapy. 2023 09; 78(9):2162-2169. doi: 10.1093/jac/dkad207. [PMID: 37428003]
  • Xiaowei Wu, Xiaoli Zhao, Xia Wang, Rouzheng Chen, Peng Liu, Weigang Liang, Junyu Wang, Di Shi, Shixiang Gao. Bioaccessibility of polypropylene microfiber-associated tetracycline and ciprofloxacin in simulated human gastrointestinal fluids. Environment international. 2023 09; 179(?):108193. doi: 10.1016/j.envint.2023.108193. [PMID: 37703772]
  • R Ricky, S Shanthakumar. An investigation on removal of ciprofloxacin and norfloxacin by phycoremediation with an emphasis on acute toxicity and biochemical composition. Scientific reports. 2023 08; 13(1):13911. doi: 10.1038/s41598-023-41144-y. [PMID: 37626153]
  • Henny Kasmawati, Ruslin Ruslin, Arfan Arfan, Nurramadhani A Sida, Dimas Isnu Saputra, Eli Halimah, Resmi Mustarichie. Antibacterial Potency of an Active Compound from Sansevieria trifasciata Prain: An Integrated In Vitro and In Silico Study. Molecules (Basel, Switzerland). 2023 Aug; 28(16):. doi: 10.3390/molecules28166096. [PMID: 37630348]
  • Saumya Singh, Taru Verma, Balaram Khamari, Eswarappa Pradeep Bulagonda, Dipankar Nandi, Siva Umapathy. Antimicrobial Resistance Studies Using Raman Spectroscopy on Clinically Relevant Bacterial Strains. Analytical chemistry. 2023 08; 95(30):11342-11351. doi: 10.1021/acs.analchem.3c01453. [PMID: 37463121]
  • Jiuyan Chen, Qiang Zhang, Yuwei Zhu, Mengli Zhang, Yutong Zhu, Usman Farooq, Taotao Lu, Zhichong Qi, Weifeng Chen. Adsorption of fluoroquinolone antibiotics onto ferrihydrite under different anionic surfactants and solution pH. Environmental science and pollution research international. 2023 Jul; 30(32):78229-78242. doi: 10.1007/s11356-023-28059-x. [PMID: 37269523]
  • K E Zannat, S K Saha, S M Tanzim, A Afrin, B C Saha, J B Joynal, M Aktar, N H Nira, N Akhter, M A Hossain. Antibacterial Effects of Chloroform Henna (Lawsonia inermis) Leaf Extracts against Two Nosocomial Infection Causing Pathogens: Gram-positive Staphylococcus aureus and Gram-negative Klebsiella pneumoniae: A Comparative Study. Mymensingh medical journal : MMJ. 2023 Jul; 32(3):620-626. doi: . [PMID: 37391949]
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