2-Pyrocatechuic acid (BioDeep_00000001192)
Secondary id: BioDeep_00000400086, BioDeep_00000405262, BioDeep_00000870598
human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite BioNovoGene_Lab2019 Volatile Flavor Compounds
代谢物信息卡片
化学式: C7H6O4 (154.0266076)
中文名称: 2,3-二羟基苯甲酸
谱图信息:
最多检出来源 Homo sapiens(blood) 0.05%
分子结构信息
SMILES: C1=CC(=C(C(=C1)O)O)C(=O)O
InChI: InChI=1S/C7H6O4/c8-5-3-1-2-4(6(5)9)7(10)11/h1-3,8-9H,(H,10,11)
描述信息
2-Pyrocatechuic acid is a normal human benzoic acid metabolite found in plasma (PMID 16351159), and is normally found with increased levels after consumption of many nutrients and drugs, i.e.: cranberry juice (PMID 14733499), aspirin ingestion. (PMID 3342084) It has been found associated with idiopathic oro-facial pain due to stress (oxidative stress might enhance the production of free radicals); it has been suggested that OH radicals are responsible for the production of many systemic and local tissue injury diseases which may initially manifest as pain syndrome, and 2-Pyrocatechuic acid is a biological marker for the detection and quantification of OH radicals, and patients had significantly increased circulating levels of 2-Pyrocatechuic acid after aspirin ingestion than control subjects. (PMID 7748148).
D064449 - Sequestering Agents > D002614 - Chelating Agents > D007502 - Iron Chelating Agents
Occurs in Gentiana lutea (yellow gentian)
Pyrocatechuic acid is a normal human benzoic acid metabolite found in plasma, and has increased levels after aspirin ingestion.
Pyrocatechuic acid is a normal human benzoic acid metabolite found in plasma, and has increased levels after aspirin ingestion.
同义名列表
26 个代谢物同义名
1,2-Dihydroxybenzene-3-carboxylic acid; 2-Pyrocatechuic acid, sodium salt; Ferri-2,3-dihydroxybenzoic acid; Catechol-3-carboxylic acid; 2,3-Dihydroxy benzoic acid; 2,3-DIHYDROXY-benzoIC ACID; 2,3-Dihydroxybenzoic acid; Catecholcarboxylic acid; 3-Hydroxysalicylic acid; Catechol-3-carboxylate; 2,3-DIHYDROXY-benzoate; 2,3-Dihydroxybenzoate; o-Pyrocatechuic acid; 2-Pyrocatechuic acid; Catecholcarboxylate; 3-Hydroxysalicylate; Pyrocatechuic acid; 2-Pyrocatechuate; O-Pyrocatechuate; Pyrocatechuate; 2,3 DHB; DOBK; DHBA; 2-Pyrocatechuic acid; NSC 27435; 2,3-Dihydroxybenzoate
数据库引用编号
22 个数据库交叉引用编号
- ChEBI: CHEBI:18026
- KEGG: C00196
- PubChem: 19
- HMDB: HMDB0000397
- Metlin: METLIN3276
- DrugBank: DB01672
- ChEMBL: CHEMBL1432
- Wikipedia: 2,3-Dihydroxybenzoic_acid
- KNApSAcK: C00002669
- foodb: FDB012200
- chemspider: 18
- CAS: 27138-57-4
- CAS: 303-38-8
- PMhub: MS000000099
- PubChem: 3496
- PDB-CCD: DBH
- 3DMET: B00056
- NIKKAJI: J79.590I
- RefMet: 2-Pyrocatechuic acid
- medchemexpress: HY-Y0202
- BioNovoGene_Lab2019: BioNovoGene_Lab2019-416
- KNApSAcK: 18026
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
6 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(6)
- Biosynthesis of Siderophore Group Nonribosomal Peptides:
2,3-Dihydroxybenzoic acid + Adenosine triphosphate + L-Serine ⟶ Adenosine monophosphate + Hydrogen Ion + Pyrophosphate + enterobactin
- Biosynthesis of Siderophore Group Nonribosomal Peptides:
2,3-Dihydroxybenzoic acid + Adenosine triphosphate + L-Serine ⟶ Adenosine monophosphate + Hydrogen Ion + Pyrophosphate + enterobactin
- 2,3-Dihydroxybenzoate Biosynthesis:
Water + isochorismate ⟶ (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate + Pyruvic acid
- Enterobactin Biosynthesis:
(2,3-Dihydroxybenzoyl)adenylic acid + a holo-[EntB isochorismatase/aryl-carrier protein] ⟶ Adenosine monophosphate + Hydrogen Ion + a 2,3-dihydroxybenzoyl-[EntB isochorismatase/aryl-carrier protein]
- 2,3-Dihydroxybenzoate Biosynthesis:
Water + isochorismate ⟶ (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate + Pyruvic acid
- Enterobactin Biosynthesis:
(2,3-Dihydroxybenzoyl)adenylic acid + a holo-[EntB isochorismatase/aryl-carrier protein] ⟶ Adenosine monophosphate + Hydrogen Ion + a 2,3-dihydroxybenzoyl-[EntB isochorismatase/aryl-carrier protein]
PharmGKB(0)
9 个相关的物种来源信息
- 1080010 - Aloe africana: 10.1021/JF071110T
- 155651 - Grosmannia huntii: 10.1139/V86-149
- 9606 - Homo sapiens: -
- 358659 - Isatis quadrialata: 10.1016/0031-9422(95)00059-G
- 591742 - Ixora javanica: 10.1016/0304-3835(90)90147-P
- 5082 - Penicillium roqueforti: 10.1271/BBB.59.319
- 1883 - Streptomyces:
- 32046 - Synechococcus elongatus: 10.1111/1462-2920.12899
- 29760 - Vitis vinifera: 10.1080/0957126032000114982
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Mengqian Lu, Yifan Zhao, Yingying Feng, Xiaoyan Tang, Wei Zhao, Keke Yu, Yuting Pan, Qiang Wang, Jilai Cui, Mengting Zhang, Jieyang Jin, Jingming Wang, Mingyue Zhao, Wilfried Schwab, Chuankui Song. 2,4-Dihydroxybenzoic Acid, a Novel SA Derivative, Controls Plant Immunity via UGT95B17-Mediated Glucosylation: A Case Study in Camellia Sinensis.
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Rapid communications in mass spectrometry : RCM.
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Food & function.
2022 May; 13(10):5602-5615. doi:
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