Maslinic acid (BioDeep_00000000171)

human metabolite PANOMIX_OTCML-2023 Endogenous blood metabolite BioNovoGene_Lab2019

代谢物信息卡片

(4aS,6aS,6bR,8aR,10R,11R,12aR,12bR,14bS)-10,11-Dihydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-octadecahydro-2H-picene-4a-carboxylic acid

化学式: C30H48O4 (472.3552408)
中文名称: 马斯里酸, 山楂酸, 2α-羟基齐墩果酸, 山楂酸，马斯里酸;
谱图信息: 最多检出来源 Viridiplantae(plant) 0.54%

分子结构信息

SMILES: CC1(C)CCC2(C(=O)O)CCC3(C)C(=CCC4C5(C)CC(O)C(O)C(C)(C)C5CCC43C)C2C1
InChI: InChI=1S/C30H48O4/c1-25(2)12-14-30(24(33)34)15-13-28(6)18(19(30)16-25)8-9-22-27(5)17-20(31)23(32)26(3,4)21(27)10-11-29(22,28)7/h8,19-23,31-32H,9-17H2,1-7H3,(H,33,34)

描述信息

Maslinic acid is a compound derived from dry olive-pomace oil (an olive skin wax) which is a byproduct of olive oil extraction. It is a member of the group of triterpenes known as oleananes.; Maslinic acid is a pentacyclic triterpene, found in the non-glyceride fraction of olive pomace oil (Olive pomace oil, also known as "orujo" olive oil, is a blend of refined-pomace oil and virgin olive oil, fit for human consumption). Pentacyclic triterpenes are natural compounds which are widely distributed in plants. These natural products have been demonstrated to possess anti-inflammatory properties. Triterpenoids have been reported to possess antioxidant properties, since they prevent lipid peroxidation and suppress superoxide anion generation. The triterpenes have a history of medicinal use in many Asian countries. Maslinic acid exhibits both pro- and anti-inflammatory properties depending on chemical structure and dose and may be useful in modulating the immune response; further studies are required to confirm the immunomodulatory behaviour of this triterpenoid, and characterise the mechanisms underlying the biphasic nature of some aspects of the inflammatory response. (PMID: 17292619)
Maslinic acid is a pentacyclic triterpene, found in the non-glyceride fraction of olive pomace oil (Olive pomace oil, also known as "orujo" olive oil, is a blend of refined-pomace oil and virgin olive oil, fit for human consumption). Pentacyclic triterpenes are natural compounds which are widely distributed in plants. These natural products have been demonstrated to possess anti-inflammatory properties. Triterpenoids have been reported to possess antioxidant properties, since they prevent lipid peroxidation and suppress superoxide anion generation. The triterpenes have a history of medicinal use in many Asian countries. Maslinic acid exhibits both pro- and anti-inflammatory properties depending on chemical structure and dose and may be useful in modulating the immune response; further studies are required to confirm the immunomodulatory behaviour of this triterpenoid, and characterise the mechanisms underlying the biphasic nature of some aspects of the inflammatory response. (PMID: 17292619).
Maslinic acid is a pentacyclic triterpenoid that is olean-12-ene substituted by hydroxy groups at positions 2 and 3 and a carboxy group at position 28 (the 2alpha,3beta stereoisomer). It is isolated from Olea europaea and Salvia canariensis and exhibits anti-inflammatory, antioxidant and antineoplastic activity. It has a role as an antioxidant, an antineoplastic agent, an anti-inflammatory agent and a plant metabolite. It is a pentacyclic triterpenoid and a dihydroxy monocarboxylic acid. It derives from a hydride of an oleanane.
Maslinic acid is a natural product found in Chaenomeles speciosa, Salvia tomentosa, and other organisms with data available.
See also: Centaurium erythraea whole (part of).
A pentacyclic triterpenoid that is olean-12-ene substituted by hydroxy groups at positions 2 and 3 and a carboxy group at position 28 (the 2alpha,3beta stereoisomer). It is isolated from Olea europaea and Salvia canariensis and exhibits anti-inflammatory, antioxidant and antineoplastic activity.
Maslinic acid can inhibit the DNA-binding activity of NF-κB p65 and abolish the phosphorylation of IκB-α, which is required for p65 activation.
Maslinic acid can inhibit the DNA-binding activity of NF-κB p65 and abolish the phosphorylation of IκB-α, which is required for p65 activation.

同义名列表

43 个代谢物同义名

数据库引用编号

23 个数据库交叉引用编号

ChEBI: CHEBI:66682
KEGG: C16939
PubChem: 73659
PubChem: 3694932
HMDB: HMDB0002392
Metlin: METLIN44861
ChEMBL: CHEMBL201515
Wikipedia: Maslinic_acid
LipidMAPS: LMPR0106180014
MeSH: maslinic acid
ChemIDplus: 0004373415
KNApSAcK: C00030742
KNApSAcK: C00029762
foodb: FDB013041
chemspider: 66312
CAS: 4373-41-5
medchemexpress: HY-N0629
PMhub: MS000004117
MetaboLights: MTBLC66682
PubChem: 96023428
NIKKAJI: J22.580K
RefMet: Maslinic acid
BioNovoGene_Lab2019: BioNovoGene_Lab2019-806

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

135 个相关的物种来源信息

3625 - Actinidia chinensis: 10.1016/J.FITOTE.2010.06.007
3625 - Actinidia Chinensis Planch: -
59970 - Aegiceras corniculatum: 10.1021/NP200789S
155132 - Akebia trifoliata:
516068 - Anisomeles: 10.1021/NP800147Z
516069 - Anisomeles indica: 10.1021/NP800147Z
545239 - Bidens subalternans: 10.1055/S-2006-957586
69056 - Buddleja asiatica: 10.1515/ZNB-2008-0717
4270 - Byrsonima crassifolia: 10.1016/S0031-9422(96)00842-4
996322 - Cantinoa mutabilis: 10.1021/NP50059A035
79559 - Careya arborea: 10.1016/0031-9422(82)83045-8
36622 - Chaenomeles sinensis: 10.1248/CPB.51.1318
106546 - Chaenomeles speciosa: 10.3390/MOLECULES15118507
986250 - Condea verticillata: 10.1021/NP50100A011
60117 - Cornus capitata: 10.1021/NP50046A034
16906 - Cornus Officinalis Sieb. Et Zucc.: -
510735 - Crataegus pinnatifida: 10.1021/JF903337F
169244 - Dillenia philippinensis: 10.1248/CPB.59.397
1948899 - Diospyros melanoxylon:
140964 - Durio kutejensis: 10.1021/NP050553T
75585 - Elliottia paniculata: 10.1248/YAKUSHI1947.94.12_1634
183809 - Eucalyptus albens: 10.1007/BF00714930
34316 - Eucalyptus camaldulensis: 10.1007/BF00714930
34317 - Eucalyptus globulus: 10.1007/BF00714930
34318 - Eucalyptus leucoxylon: 10.1007/BF00714930
36592 - Eucalyptus obliqua: 10.1007/BF00714930
155760 - Eucalyptus ovata: 10.1007/BF00714930
183845 - Eucalyptus perriniana: 10.1016/S0031-9422(00)84771-8
183847 - Eucalyptus polyanthemos: 10.1007/BF00714930
1541731 - Eucalyptus sideroxylon: 10.1007/BF00714930
183855 - Eucalyptus tereticornis: 10.1007/BF00714930
155764 - Eucalyptus viminalis: 10.1007/BF00579992
1442725 - Euonymus nanoides: 10.1248/CPB.54.219
2835888 - Euphorbia sororia: 10.1007/S10600-010-9459-Y
13523 - Euptelea polyandra:
212252 - Galphimia glauca: 10.1055/S-2006-931601
1240870 - Gardenia tubifera: 10.1021/NP800002Z
225203 - Gentiana dahurica: 10.1002/HLCA.201000095
714473 - Geum aleppicum:
321607 - Geum japonicum:
32229 - Geum macrophyllum:
9606 - Homo sapiens: -
204122 - Hyptis: 10.1021/NP9001724
204123 - Hyptis brevipes: 10.1021/NP9001724
204124 - Hyptis capitata: 10.1016/0031-9422(88)80028-1
662909 - Isodon flavidus:
662913 - Isodon glutinosus: 10.1007/S10600-014-1130-6
662932 - Isodon yuennanensis: 10.1016/0031-9422(91)85279-9
51240 - Juglans regia: 10.1021/NP1008202
122810 - Lagerstroemia speciosa: 10.1248/CPB.41.2129
4136 - Lamiaceae: 10.1016/J.EJPHAR.2011.09.175
260634 - Lavandula multifida: 10.1016/J.PHYMED.2004.02.007
980664 - Lepechinia caulescens:
378905 - Leucas: 10.1021/NP058118M
483811 - Leucas aspera: 10.1021/NP058118M
1389444 - Ligusticum lucidum: 10.4268/CJCMM20100712
46072 - Ligustrum japonicum: 10.4268/CJCMM20100712
458695 - Ligustrum lucidum: 10.4268/CJCMM20100712
178760 - Ligustrum obtusifolium:
577011 - Luehea divaricata: 10.1590/S0103-50532003000300024
375239 - Luma chequen: 10.1515/ZNC-1999-1220
49153 - Lyonia ovalifolia: 10.1248/YAKUSHI1947.94.10_1349
164936 - Melaleuca leucadendra: 10.1002/JCCS.199800048
986226 - Mesosphaerum oblongifolium: 10.1016/0031-9422(90)87117-D
197124 - Microcos paniculata: 10.3390/MOLECULES15085547
1272984 - Moquilea pyrifolia: 10.1021/NP960134J
262757 - Morella rubra:
1747497 - Mucuna birdwoodiana: 10.1016/0031-9422(91)80094-H
45164 - Muntingia calabura: 10.1016/S0031-9422(03)00112-2
1317686 - Musanga cecropioides:
1781622 - Myrianthus serratus: 10.1016/S0031-9422(98)00292-1
28950 - Nothofagus pumilio: 10.1016/J.PHYTOCHEM.2004.04.002
4146 - Olea europaea:
82726 - Orphium frutescens: 10.1016/S0176-1617(11)80384-6
45171 - Paeonia suffruticosa: 10.1016/0031-9422(94)00445-Y
48386 - Perilla frutescens: 10.1007/S11418-006-0015-9
140999 - Photinia serratifolia: 10.1002/HLCA.200890070
29724 - Phytolacca dodecandra:
33090 - Plants: -
2485399 - Plectranthus punctatus: 10.1002/CBDV.200900193
58884 - Polygala amara: 10.1248/CPB.54.1739
2072282 - Pourouma guianensis: 10.1078/0944-7113-00381
39358 - Prunella vulgaris:
379279 - Prunus africana:
22662 - Punica: 10.1248/CPB.56.1628
22663 - Punica granatum:
193309 - Pyracantha coccinea: 10.1016/S0040-4020(01)90428-4
237596 - Rosa davurica: 10.1248/CPB.37.2232
74652 - Rosa laevigata: 10.1021/NP1007922
1650721 - Rubia yunnanensis: 10.1021/NP2002918
49210 - Salvia canariensis: 10.1021/NP50028A032
1749387 - Salvia carduacea: 10.1021/NP020178U
260612 - Salvia coccinea: 10.1016/0031-9422(90)85143-4
342061 - Salvia deserta: 10.1016/S0031-9422(00)82493-0
1520021 - Salvia deserti: 10.1016/S0031-9422(00)82493-0
392636 - Salvia dianthera: 10.1021/JO00174A030
392661 - Salvia fulgens: 10.1016/0031-9422(83)85059-6
2263203 - Salvia hierosolymitana: 10.1016/0031-9422(90)80046-J
226208 - Salvia miltiorrhiza: 10.1002/HLCA.201000154
49215 - Salvia nemorosa: 10.1016/0031-9422(90)85143-4
38868 - Salvia officinalis:
268920 - Salvia palaestina: 10.1016/S0031-9422(00)81143-7
1933756 - Salvia sahendica: 10.1021/NP1002516
1132405 - Salvia tomentosa:
342065 - Salvia trijuga: 10.1021/NP100250W
49220 - Salvia verticillata: 10.1021/NP50036A047
1298553 - Salvia virgata: 10.1016/0031-9422(90)85143-4
49988 - Satureja montana: 10.1021/NP50037A025
1986532 - Scutellaria strigillosa: 10.1007/S11418-005-0023-1
155236 - Sideritis candicans: 10.1016/0305-1978(95)00067-4
239704 - Symplocos lancifolia: 10.1021/NP100502Y
112400 - Syncarpha gnaphaloides: 10.1016/0031-9422(91)84127-E
178762 - Syringa oblata: 10.1016/J.PHYTOL.2018.07.009
126367 - Syringa reticulata: 10.1248/YAKUSHI1947.107.1_23
219868 - Syzygium aromaticum:
334497 - Syzygium sandwicense: 10.1016/S0031-9422(01)00180-7
334497 - Syzygium sandwicense: 10.1016/S0031-9422(98)00091-0
155022 - Terminalia chebula: 10.1016/0031-9422(90)83072-9
1924228 - Terminalia glabrescens: 10.1590/S0103-50532003000300021
1507733 - Terminalia pallida: 10.1016/S0367-326X(99)00060-X
59683 - Ternstroemia: 10.1021/NP030069V
13715 - Tetracentron sinense: 10.1016/S0031-9422(99)00457-4
619227 - Thalictrum aquilegiifolium: 10.1248/CPB.34.726
324797 - Thomandersia laurifolia:
226819 - Trogopterus xanthipes: 10.1248/CPB.37.648
198266 - Ulmus pumila: 10.1248/CPB.54.775
237931 - Viburnum cylindricum: 10.1002/HLCA.200800420
54477 - Vitex agnus-castus: 10.1248/CPB.59.392
549680 - Vitex altissima: 10.1016/J.PHYTOCHEM.2005.05.008
177074 - Vochysia ferruginea: 10.1590/S0103-50532000000300007
751879 - Ziziphora clinopodioides: 10.1248/CPB.60.397
326968 - Ziziphus jujuba: 10.1248/CPB.26.3075
326968 - Ziziphus jujuba Mill.: -
33090 - 大枣: -
33090 - 山楂叶: -

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Kun Yang, Sheng-Bing Wang, Dong Pei, Lu-Mei Pu, Xin-Yi Huang. Effective separation of maslinic acid and oleanolic acid from olive pomace using high-speed shear off-line coupled with high-speed countercurrent chromatography and their antibacterial activity test. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2024 Apr; 1236(?):124069. doi: 10.1016/j.jchromb.2024.124069. [PMID: 38442634]
Marta Ramos-Barbero, Eva E Rufino-Palomares, Sergio Serrano-Carmona, Manuel Hernández-Yera, Leticia García-Salguero, José Antonio Lupiáñez, Amalia Pérez-Jiménez. Effect of Nutraceutical Factors on Hepatic Intermediary Metabolism in Wistar Rats with Induced Tendinopathy. International journal of molecular sciences. 2024 Jan; 25(1):. doi: 10.3390/ijms25010629. [PMID: 38203800]
Aixa Aguilera-Garrido, Pablo Graván, Saúl A Navarro-Marchal, Marta Medina-O'Donnell, Andrés Parra, María José Gálvez-Ruiz, Juan Antonio Marchal, Francisco Galisteo-González. Maslinic acid solid lipid nanoparticles as hydrophobic anticancer drug carriers: Formulation, in vitro activity and in vivo biodistribution. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2023 Jul; 163(?):114828. doi: 10.1016/j.biopha.2023.114828. [PMID: 37163783]
Elisabeta-Irina Geana, Corina Teodora Ciucure, Irina Mirela Apetrei, Maria Lisa Clodoveo, Constantin Apetrei. Discrimination of Olive Oil and Extra-Virgin Olive Oil from Other Vegetable Oils by Targeted and Untargeted HRMS Profiling of Phenolic and Triterpenic Compounds Combined with Chemometrics. International journal of molecular sciences. 2023 Mar; 24(6):. doi: 10.3390/ijms24065292. [PMID: 36982366]
Fiammetta Alagna, James Reed, Ornella Calderini, Ramesha Thimmappa, Nicolò G M Cultrera, Alice Cattivelli, Davide Tagliazucchi, Soraya Mousavi, Roberto Mariotti, Anne Osbourn, Luciana Baldoni. OeBAS and CYP716C67 catalyze the biosynthesis of health-beneficial triterpenoids in olive (Olea europaea L.) fruits. The New phytologist. 2023 Mar; ?(?):. doi: 10.1111/nph.18863. [PMID: 36880371]
Yan He, Yi Wang, Kun Yang, Jia Jiao, Hong Zhan, Youjun Yang, De Lv, Weihong Li, Weijun Ding. Maslinic Acid: A New Compound for the Treatment of Multiple Organ Diseases. Molecules (Basel, Switzerland). 2022 Dec; 27(24):. doi: 10.3390/molecules27248732. [PMID: 36557864]
Lin Wang, Yi-Fu Fan, Bing-Rui Li, Wen-Hui Sun, Li-Na Wang. Maslinic Acid Suppresses High Glucose-induced Inflammation by Epigenetically Inhibiting TXNIP Expression. Current medical science. 2022 Dec; 42(6):1213-1219. doi: 10.1007/s11596-022-2657-6. [PMID: 36350490]
Aixa Aguilera-Garrido, Elena Arranz, María José Gálvez-Ruiz, Juan Antonio Marchal, Francisco Galisteo-González, Linda Giblin. Solid lipid nanoparticles to improve bioaccessibility and permeability of orally administered maslinic acid. Drug delivery. 2022 Dec; 29(1):1971-1982. doi: 10.1080/10717544.2022.2086937. [PMID: 35762633]
Tianqi Li, Huan Wang, Siyu Dong, Meng Liang, Jun Ma, XiaoWen Jiang, Wenhui Yu. Protective effects of maslinic acid on high fat diet-induced liver injury in mice. Life sciences. 2022 Jul; 301(?):120634. doi: 10.1016/j.lfs.2022.120634. [PMID: 35568228]
Lin Li, Lei Lin, Shaoqing Lei, Si Shi, Chun Chen, Zhongyuan Xia. Maslinic Acid Inhibits Myocardial Ischemia-Reperfusion Injury-Induced Apoptosis and Necroptosis via Promoting Autophagic Flux. DNA and cell biology. 2022 May; 41(5):487-497. doi: 10.1089/dna.2021.0918. [PMID: 35475713]
Karabo R Matee, Akinjide M Akinnuga, Angezwa Siboto, Phikelelani Ngubane, Andile Khathi. Bredemolic acid restores glucose utilization and attenuates oxidative stress in palmitic acid-induced insulin-resistant C2C12 cells. Endocrine regulations. 2022 Apr; 56(2):126-133. doi: 10.2478/enr-2022-0014. [PMID: 35489052]
Akinjide Moses Akinnuga, Angezwa Siboto, Bongiwe Khumalo, Ntethelelo Hopewell Sibiya, Phikelelani Ngubane, Andile Khathi. Evaluation of the effects of bredemolic acid on selected markers of glucose homeostasis in diet-induced prediabetic rats. Archives of physiology and biochemistry. 2022 Apr; 128(2):306-312. doi: 10.1080/13813455.2019.1680697. [PMID: 31686537]
Huijuan Gao, Hong Wu. Maslinic acid activates renal AMPK/SIRT1 signaling pathway and protects against diabetic nephropathy in mice. BMC endocrine disorders. 2022 Jan; 22(1):25. doi: 10.1186/s12902-022-00935-6. [PMID: 35042497]
Jiuwei Chen, Lin Wang. Maslinic Acid Inhibits Cervical Intraepithelial Neoplasia by Suppressing Interleukin- 6 and Enhancing Apoptosis in a Mouse Model. Anti-cancer agents in medicinal chemistry. 2022; 22(3):579-585. doi: 10.2174/1871520621666210903143922. [PMID: 34477530]
Ghassab M Al-Mazaideh, Mohammed Hf Shalayel, Saada Nour, Farhan Khashim Al-Swailmi, Saleem Aladaileh. In silico anti-fungal efficacy and the mechanism of binding of some Syzygium aromaticum ingredient compounds to aspartate semialdehyde dehydrogenase, 6C8W and 6C85, enzymes from Blastomyces dermatitidis. Pakistan journal of pharmaceutical sciences. 2021 Nov; 34(6):2219-2226. doi: . [PMID: 35034884]
Hani A Alhadrami, Ahmed M Sayed, Ahmed M Sharif, Esam I Azhar, Mostafa E Rateb. Olive-Derived Triterpenes Suppress SARS COV-2 Main Protease: A Promising Scaffold for Future Therapeutics. Molecules (Basel, Switzerland). 2021 May; 26(9):. doi: 10.3390/molecules26092654. [PMID: 34062737]
Khong Trong Quan, Byung Gu Min, In Hyun Hwang, Yeon Jung Choi, Sang Kyum Kim, MinKyun Na. Oleanane triterpenoids from Rubia philippinensis and their inhibitory effect on 20-HETE synthesis. Natural product research. 2021 Apr; 35(8):1267-1273. doi: 10.1080/14786419.2019.1645656. [PMID: 31343260]
Lei Yu, Xiaofang Xie, Xiaoyu Cao, Junren Chen, Guanru Chen, Yan Chen, Gangmin Li, Junyuan Qin, Fu Peng, Cheng Peng. The Anticancer Potential of Maslinic Acid and Its Derivatives: A Review. Drug design, development and therapy. 2021; 15(?):3863-3879. doi: 10.2147/dddt.s326328. [PMID: 34526766]
Liu Liu, Haobin Li, Kaiwen Hu, Qinglong Xu, Xiaoan Wen, Keguang Cheng, Caiping Chen, Haoliang Yuan, Liang Dai, Hongbin Sun. Synthesis and anti-inflammatory activity of saponin derivatives of δ-oleanolic acid. European journal of medicinal chemistry. 2021 Jan; 209(?):112932. doi: 10.1016/j.ejmech.2020.112932. [PMID: 33131725]
Kung-Wen Lu, Mei-Due Yang, Shu-Fen Peng, Jaw-Chyun Chen, Po-Yuan Chen, Hung-Yi Chen, Tai-Jung Lu, Fu-Shin Chueh, Jin-Cherng Lien, Kuang-Chi Lai, Kuo-Ching Liu, Yin-Ying Tai. Maslinic Acid Induces DNA Damage and Impairs DNA Repair in Human Cervical Cancer HeLa Cells. Anticancer research. 2020 Dec; 40(12):6869-6877. doi: 10.21873/anticanres.14709. [PMID: 33288579]
Feng Zhang, Jian Huang, Rong-Jing He, Lu Wang, Peng-Chao Huo, Xiao-Qing Guan, Sheng-Quan Fang, Yan-Wei Xiang, Shou-Ning Jia, Guang-Bo Ge. Herb-drug interaction between Styrax and warfarin: Molecular basis and mechanism. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2020 Oct; 77(?):153287. doi: 10.1016/j.phymed.2020.153287. [PMID: 32739573]
Rafael de la Torre, Marceli Carbó, Mitona Pujadas, Sarah Biel, María-Dolores Mesa, María-Isabel Covas, Manuela Expósito, Juan-Antonio Espejo, Estefanía Sanchez-Rodriguez, Patricia Díaz-Pellicer, Francisco Jimenez-Valladares, Carmen Rosa, Oscar Pozo, Montserrat Fitó. Pharmacokinetics of maslinic and oleanolic acids from olive oil - Effects on endothelial function in healthy adults. A randomized, controlled, dose-response study. Food chemistry. 2020 Aug; 322(?):126676. doi: 10.1016/j.foodchem.2020.126676. [PMID: 32305871]
Su Wen Phang, Bee Kee Ooi, Nafees Ahemad, Wei Hsum Yap. Maslinic acid suppresses macrophage foam cells formation: Regulation of monocyte recruitment and macrophage lipids homeostasis. Vascular pharmacology. 2020 May; 128-129(?):106675. doi: 10.1016/j.vph.2020.106675. [PMID: 32200116]
Akinjide Moses Akinnuga, Angezwa Siboto, Bongiwe Khumalo, Ntethelelo Hopewell Sibiya, Phikelelani Ngubane, Andile Khathi. Bredemolic Acid Improves Cardiovascular Function and Attenuates Endothelial Dysfunction in Diet-Induced Prediabetes: Effects on Selected Markers. Cardiovascular therapeutics. 2020; 2020(?):1936406. doi: 10.1155/2020/1936406. [PMID: 32117470]
Akinjide Moses Akinnuga, Angezwa Siboto, Bongiwe Khumalo, Ntethelelo Hopewell Sibiya, Phikelelani Ngubane, Andile Khathi. Ameliorative Effects of Bredemolic Acid on Markers Associated with Renal Dysfunction in a Diet-Induced Prediabetic Rat Model. Oxidative medicine and cellular longevity. 2020; 2020(?):2978340. doi: 10.1155/2020/2978340. [PMID: 32655765]
Akinjide Moses Akinnuga, Angezwa Siboto, Bongiwe Khumalo, Ntethelelo Hopewell Sibiya, Phikelelani Ngubane, Andile Khathi. Bredemolic Acid Ameliorates Selected Liver Function Biomarkers in a Diet-Induced Prediabetic Rat Model. Canadian journal of gastroenterology & hepatology. 2020; 2020(?):2475301. doi: 10.1155/2020/2475301. [PMID: 32149046]
Blessing Nkazimulo Mkhwanazi, Fanie Retief van Heerden, Greanious Alfred Mavondo, Musa Vuyisile Mabandla, Cephas Tagumirwa Musabayane. Triterpene derivative improves the renal function of streptozotocin-induced diabetic rats: a follow-up study on maslinic acid. Renal failure. 2019 Nov; 41(1):547-554. doi: 10.1080/0886022x.2019.1623818. [PMID: 31234683]
Chian-Jiun Liou, Yi-Wen Dai, Chia-Ling Wang, Li-Wen Fang, Wen-Chung Huang. Maslinic acid protects against obesity-induced nonalcoholic fatty liver disease in mice through regulation of the Sirt1/AMPK signaling pathway. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2019 11; 33(11):11791-11803. doi: 10.1096/fj.201900413rrr. [PMID: 31361524]
Dimitris Tsoukalas, Persefoni Fragkiadaki, Anca Oana Docea, Athanasios K Alegakis, Evangelia Sarandi, Maria Thanasoula, Demetrios A Spandidos, Aristidis Tsatsakis, Mayya Petrovna Razgonova, Daniela Calina. Discovery of potent telomerase activators: Unfolding new therapeutic and anti-aging perspectives. Molecular medicine reports. 2019 Oct; 20(4):3701-3708. doi: 10.3892/mmr.2019.10614. [PMID: 31485647]
Xin-Yi Huang, Xia Zhang, Dong Pei, Jian-Fei Liu, Yuan Gong, Haji Akber Aisa, Duo-Long Di. Continuous separation of maslinic and oleanolic acids from olive pulp by high-speed countercurrent chromatography with elution-extrusion mode. Journal of separation science. 2019 Jun; 42(11):2080-2088. doi: 10.1002/jssc.201900112. [PMID: 31087537]
M Emília Juan, Glòria Lozano-Mena, Marta Sánchez-González, Joana M Planas. Reduction of Preneoplastic Lesions Induced by 1,2-Dimethylhydrazine in Rat Colon by Maslinic Acid, a Pentacyclic Triterpene from Olea europaea L. Molecules (Basel, Switzerland). 2019 Apr; 24(7):. doi: 10.3390/molecules24071266. [PMID: 30939812]
Zhubo Dai, Yun Liu, Zhoutong Sun, Dong Wang, Ge Qu, Xiaolin Ma, Feiyu Fan, Lili Zhang, Shoulian Li, Xueli Zhang. Identification of a novel cytochrome P450 enzyme that catalyzes the C-2α hydroxylation of pentacyclic triterpenoids and its application in yeast cell factories. Metabolic engineering. 2019 01; 51(?):70-78. doi: 10.1016/j.ymben.2018.10.001. [PMID: 30339834]
Aymen Ben Nejma, Mansour Znati, Adam Daich, Mohamed Othman, Ata Martin Lawson, Hichem Ben Jannet. Design and semisynthesis of new herbicide as 1,2,3-triazole derivatives of the natural maslinic acid. Steroids. 2018 Oct; 138(?):102-107. doi: 10.1016/j.steroids.2018.07.004. [PMID: 30016641]
Joaquín Velasco, Francisca Holgado, Gloria Márquez-Ruiz, María Victoria Ruiz-Méndez. Concentrates of triterpenic acids obtained from crude olive pomace oils: characterization and evaluation of their potential antioxidant activity. Journal of the science of food and agriculture. 2018 Oct; 98(13):4837-4844. doi: 10.1002/jsfa.9012. [PMID: 29574746]
Xiukun Lin, Ulku Ozbey, Uteuliyev Yerzhan Sabitaliyevich, Rukset Attar, Beraat Ozcelik, Yuanyan Zhang, Mingyue Guo, Minghua Liu, Saleh S Alhewairini, Ammad Ahmad Farooqi. Maslinic acid as an effective anticancer agent. Cellular and molecular biology (Noisy-le-Grand, France). 2018 Jul; 64(10):87-91. doi: . [PMID: 30084808]
Yao Li, Sheng Guo, Quanjin Ren, Dandan Wei, Ming Zhao, Shulan Su, Zhishu Tang, Jin-Ao Duan. Pharmacokinetic Comparisons of Multiple Triterpenic Acids from Jujubae Fructus Extract Following Oral Delivery in Normal and Acute Liver Injury Rats. International journal of molecular sciences. 2018 07; 19(7):. doi: 10.3390/ijms19072047. [PMID: 30011885]
Yuan-Yuan Wang, Bao-Zhong Diao, Li-Hua Zhong, Bao-Ling Lu, Yu Cheng, Lei Yu, Li-Ying Zhu. Maslinic acid protects against lipopolysaccharide/d-galactosamine-induced acute liver injury in mice. Microbial pathogenesis. 2018 Jun; 119(?):49-53. doi: 10.1016/j.micpath.2018.04.002. [PMID: 29627448]
Wei Hsum Yap, Bee Kee Ooi, Nafees Ahmed, Yang Mooi Lim. Maslinic acid modulates secreted phospholipase A2-IIA (sPLA2-IIA)-mediated inflammatory effects in macrophage foam cells formation. Journal of biosciences. 2018 Jun; 43(2):277-285. doi: . [PMID: 29872016]
Christina E Mair, Ulrike Grienke, Anke Wilhelm, Ernst Urban, Martin Zehl, Michaela Schmidtke, Judith M Rollinger. Anti-Influenza Triterpene Saponins from the Bark of Burkea africana. Journal of natural products. 2018 03; 81(3):515-523. doi: 10.1021/acs.jnatprod.7b00774. [PMID: 29394063]
Ninh Khac Ban, Nguyen Thi Kim Thoa, Tran My Linh, Do Thi Trang, Phan Van Kiem, Nguyen Xuan Nhiem, Bui Huu Tai, Chau Van Minh, Jae-Hyoung Song, Hyun-Jeong Ko, Seung Hyun Kim. Labdane-type diterpenoids from Vitex limonifolia and their antivirus activities. Journal of natural medicines. 2018 Jan; 72(1):290-297. doi: 10.1007/s11418-017-1125-2. [PMID: 28914420]
Zhi-Hong Wang, Mei-Chin Mong, Ya-Chen Yang, Mei-Chin Yin. Asiatic acid and maslinic acid attenuated kainic acid-induced seizure through decreasing hippocampal inflammatory and oxidative stress. Epilepsy research. 2018 01; 139(?):28-34. doi: 10.1016/j.eplepsyres.2017.11.003. [PMID: 29156327]
Roseane Leandra da Rosa, Luciane Ângela Nottar Nesello, Luisa Nathalia Bolda Mariano, Lincon Bordignon Somensi, Adriana Campos, Ana Myrelle Pinheiro, Sabrina Costa, Marjana Rial, Mariana Tozzo, Valdir Cechinel-Filho, Sérgio Faloni de Andrade, Luísa Mota Da Silva. Gastroprotective activity of the methanol extract from peels of Plinia edulis (Vell.) Sobral fruits and its isolated triterpenes: maslinic and ursolic acids. Naunyn-Schmiedeberg's archives of pharmacology. 2018 01; 391(1):95-101. doi: 10.1007/s00210-017-1442-8. [PMID: 29209743]
Se Jin Jeon, Eunji Kim, Jin Su Lee, Hee Kyong Oh, Jiabao Zhang, Yubeen Kwon, Dae Sik Jang, Jong Hoon Ryu. Maslinic acid ameliorates NMDA receptor blockade-induced schizophrenia-like behaviors in mice. Neuropharmacology. 2017 Nov; 126(?):168-178. doi: 10.1016/j.neuropharm.2017.09.014. [PMID: 28899728]
Oscar J Pozo, Mitona Pujadas, Sarah Biel Gleeson, Maria Dolores Mesa-García, Antoni Pastor, Aristotelis Kotronoulas, Montserrat Fitó, Maria-Isabel Covas, José Ramón Fernández Navarro, Juan Antonio Espejo, Estefania Sanchez-Rodriguez, Rosa Marchal, Miguel Angel Calleja, Rafael de la Torre. Liquid chromatography tandem mass spectrometric determination of triterpenes in human fluids: Evaluation of markers of dietary intake of olive oil and metabolic disposition of oleanolic acid and maslinic acid in humans. Analytica chimica acta. 2017 Oct; 990(?):84-95. doi: 10.1016/j.aca.2017.07.041. [PMID: 29029746]
Nguyen Huu Tung, Kensuke Nakajima, Takuhiro Uto, Nguyen Thanh Hai, Dinh Doan Long, Tomoe Ohta, Shigeru Oiso, Hiroko Kariyazono, Yukihiro Shoyama. Bioactive Triterpenes from the Root of Salvia miltiorrhiza Bunge. Phytotherapy research : PTR. 2017 Sep; 31(9):1457-1460. doi: 10.1002/ptr.5877. [PMID: 28766764]
Yui Kaneta, Midori A Arai, Naoki Ishikawa, Kazufumi Toume, Takashi Koyano, Thaworn Kowithayakorn, Tetsuhiro Chiba, Atsushi Iwama, Masami Ishibashi. Identification of BMI1 Promoter Inhibitors from Beaumontia murtonii and Eugenia operculata. Journal of natural products. 2017 06; 80(6):1853-1859. doi: 10.1021/acs.jnatprod.7b00138. [PMID: 28598616]
Miroslav Novakovic, Jasmina Nikodinovic-Runic, Jovana Veselinovic, Tatjana Ilic-Tomic, Vera Vidakovic, Vele Tesevic, Slobodan Milosavljevic. Bioactive Pentacyclic Triterpene Ester Derivatives from Alnus viridis ssp. viridis Bark. Journal of natural products. 2017 05; 80(5):1255-1263. doi: 10.1021/acs.jnatprod.6b00805. [PMID: 28368586]
Chung Sub Kim, Lalita Subedi, Joonseok Oh, Sun Yeou Kim, Sang Un Choi, Kang Ro Lee. Bioactive Triterpenoids from the Twigs of Chaenomeles sinensis. Journal of natural products. 2017 04; 80(4):1134-1140. doi: 10.1021/acs.jnatprod.7b00111. [PMID: 28358502]
Thanh Tra Nguyen, Bich Ngan Truong, Huong Doan Thi Mai, Marc Litaudon, Van Hung Nguyen, Thao Do Thi, Van Minh Chau, Van Cuong Pham. Cytotoxic dammarane-type triterpenoids from the leaves of Viburnum sambucinum. Bioorganic & medicinal chemistry letters. 2017 04; 27(8):1665-1669. doi: 10.1016/j.bmcl.2017.03.014. [PMID: 28318944]
Maria Ferhat, Zahia Kabouchea, Yoshinori Fujimoto, Hiroshi Araya. Two New Triterpenes and Other Compounds from Mentha aquatica (Lamiaceae). Natural product communications. 2017 Apr; 12(4):483-486. doi: ". [PMID: 30520576]
Prasad G Jamkhande, Shahbaz K Pathan, Shailesh J Wadher. In silico PASS analysis and determination of antimycobacterial, antifungal, and antioxidant efficacies of maslinic acid in an extract rich in pentacyclic triterpenoids. International journal of mycobacteriology. 2016 12; 5(4):417-425. doi: 10.1016/j.ijmyco.2016.06.020. [PMID: 27931683]
Chen Wang, Ping Wu, Shuai Tian, Jinghua Xue, Liangxiong Xu, Hanxiang Li, Xiaoyi Wei. Bioactive Pentacyclic Triterpenoids from the Leaves of Cleistocalyx operculatus. Journal of natural products. 2016 11; 79(11):2912-2923. doi: 10.1021/acs.jnatprod.6b00715. [PMID: 27797185]
Amalia Pérez-Jiménez, Eva E Rufino-Palomares, Nieves Fernández-Gallego, M Carmen Ortuño-Costela, Fernando J Reyes-Zurita, Juan Peragón, Leticia García-Salguero, Khalida Mokhtari, Pedro P Medina, José A Lupiáñez. Target molecules in 3T3-L1 adipocytes differentiation are regulated by maslinic acid, a natural triterpene from Olea europaea. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2016 Nov; 23(12):1301-1311. doi: 10.1016/j.phymed.2016.07.001. [PMID: 27765349]
Jun Cao, Li-Qing Peng, Jing-Jing Xu. Microcrystalline cellulose based matrix solid phase dispersion microextration for isomeric triterpenoid acids in loquat leaves by ultrahigh-performance liquid chromatography and quadrupole time-of-flight mass spectrometry. Journal of chromatography. A. 2016 Nov; 1472(?):16-26. doi: 10.1016/j.chroma.2016.10.034. [PMID: 27776775]
Yisong Qian, Xuzhen Tang, Teng Guan, Yunman Li, Hongbin Sun. Neuroprotection by Combined Administration with Maslinic Acid, a Natural Product from Olea europaea, and MK-801 in the Cerebral Ischemia Model. Molecules (Basel, Switzerland). 2016 Aug; 21(8):. doi: 10.3390/molecules21081093. [PMID: 27548129]
Jie Yang, Yuan-Jia Hu, Bo-Yang Yu, Jin Qi. Integrating qualitative and quantitative characterization of Prunellae Spica by HPLC-QTOF/MS and HPLC-ELSD. Chinese journal of natural medicines. 2016 May; 14(5):391-400. doi: 10.3724/sp.j.1009.2016.00391. [PMID: 27478103]
Satoshi Fukumitsu, Myra O Villareal, Takashi Fujitsuka, Kazuhiko Aida, Hiroko Isoda. Anti-inflammatory and anti-arthritic effects of pentacyclic triterpenoids maslinic acid through NF-κB inactivation. Molecular nutrition & food research. 2016 Feb; 60(2):399-409. doi: 10.1002/mnfr.201500465. [PMID: 26499467]
Mluleki Luvuno, Hlengiwe Prosperity Mbongwa, Andile Khathi. THE EFFECTS OF Syzygium aromaticum-DERIVED TRITERPENES ON GASTROINTESTINAL GHRELIN EXPRESSION IN STREPTOZOTOCIN-INDUCED DIABETIC RATS. African journal of traditional, complementary, and alternative medicines : AJTCAM. 2016; 13(4):8-14. doi: 10.21010/ajtcam.v13i4.2. [PMID: 28852714]
Li Zhang, Dong Pei, Yan-ru Huang, Jian-teng Wei, Duo-long Di, Lan-xia Wang. [Chemical Constituents from Cynomorium songaricum]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2016 Jan; 39(1):74-7. doi: . [PMID: 30079707]
A Venditti, C Frezza, M Riccardelli, S Foddai, M Nicoletti, M Serafini, A Bianco. Unusual molecular pattern in Ajugoideae subfamily: the case of Ajuga genevensis L. from Dolomites. Natural product research. 2016; 30(9):1098-102. doi: 10.1080/14786419.2015.1102140. [PMID: 26508158]
Jiyoon Cho, Lisa Tremmel, Okkyung Rho, Andrew M Camelio, Dionicio Siegel, Thomas J Slaga, John DiGiovanni. Evaluation of pentacyclic triterpenes found in Perilla frutescens for inhibition of skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate. Oncotarget. 2015 Nov; 6(36):39292-306. doi: 10.18632/oncotarget.5751. [PMID: 26513295]
Xue Wang, Haribalan Perumalsamy, Hyung Wook Kwon, Young-Eun Na, Young-Joon Ahn. Effects and possible mechanisms of action of acacetin on the behavior and eye morphology of Drosophila models of Alzheimer's disease. Scientific reports. 2015 Nov; 5(?):16127. doi: 10.1038/srep16127. [PMID: 26530776]
Yi-chih Hung, Hui-ting Yang, Mei-chin Yin. Asiatic acid and maslinic acid protected heart via anti-glycative and anti-coagulatory activities in diabetic mice. Food & function. 2015 Sep; 6(9):2967-74. doi: 10.1039/c5fo00549c. [PMID: 26190771]
Jian-you Huang, Wen-jie Lu, Xiao Tan, Guo-shou Lu, Zhou-feng Huang. [Chemical Constituents from Macaranga denticulata Root]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2015 Aug; 38(8):1671-3. doi: . [PMID: 26983243]
Qing Wang, Qiaomei Sun, Xiangling Ma, Zaisheng Rao, Hui Li. Probing the binding interaction of human serum albumin with three bioactive constituents of Eriobotrta japonica leaves: Spectroscopic and molecular modeling approaches. Journal of photochemistry and photobiology. B, Biology. 2015 Jul; 148(?):268-276. doi: 10.1016/j.jphotobiol.2015.04.030. [PMID: 25985147]
Hongliang Wu, Guoliang Li, Shucheng Liu, Di Liu, Guang Chen, Na Hu, Yourui Suo, Jinmao You. Simultaneous determination of six triterpenic acids in some Chinese medicinal herbs using ultrasound-assisted dispersive liquid-liquid microextraction and high-performance liquid chromatography with fluorescence detection. Journal of pharmaceutical and biomedical analysis. 2015 Mar; 107(?):98-107. doi: 10.1016/j.jpba.2014.10.031. [PMID: 25569287]
A Venditti, M Serafini, M Nicoletti, A Bianco. Terpenoids of Linaria alpina (L.) Mill. from Dolomites, Italy. Natural product research. 2015; 29(21):2041-4. doi: 10.1080/14786419.2015.1018252. [PMID: 25738749]
Su Yeong Kim, Jung Eun Kim, Hee Jung Bu, Chang-Gu Hyun, Nam Ho Lee. Chemical constituents of Tilia taquetii leaves and their inhibition of MMP-1 expression and elastase activities. Natural product communications. 2014 Dec; 9(12):1683-5. doi: . [PMID: 25632458]
Ines Sifaoui, Atteneri López-Arencibia, Carmen Maria Martín-Navarro, Juan Carlos Ticona, María Reyes-Batlle, Mondher Mejri, Antonio Ignacio Jiménez, Isabel Lopez-Bazzocchi, Basilio Valladares, Jacob Lorenzo-Morales, Manef Abderabba, José E Piñero. In vitro effects of triterpenic acids from olive leaf extracts on the mitochondrial membrane potential of promastigote stage of Leishmania spp. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2014 Oct; 21(12):1689-94. doi: 10.1016/j.phymed.2014.08.004. [PMID: 25442278]
Marta Sánchez-González, Helena Colom, Glòria Lozano-Mena, M Emília Juan, Joana M Planas. Population pharmacokinetics of maslinic acid, a triterpene from olives, after intravenous and oral administration in rats. Molecular nutrition & food research. 2014 Oct; 58(10):1970-9. doi: 10.1002/mnfr.201400147. [PMID: 25045029]
Blessing N Mkhwanazi, Metse R Serumula, Rene B Myburg, Fanie R Van Heerden, Cephas T Musabayane. Antioxidant effects of maslinic acid in livers, hearts and kidneys of streptozotocin-induced diabetic rats: effects on kidney function. Renal failure. 2014 Apr; 36(3):419-31. doi: 10.3109/0886022x.2013.867799. [PMID: 24344651]
Jun Liu, Xue Wang, Yu-Peng Chen, Li-Fei Mao, Jing Shang, Hong-Bin Sun, Lu-Yong Zhang. Maslinic acid modulates glycogen metabolism by enhancing the insulin signaling pathway and inhibiting glycogen phosphorylase. Chinese journal of natural medicines. 2014 Apr; 12(4):259-65. doi: 10.1016/s1875-5364(14)60052-2. [PMID: 24863350]
Andres Parra, Samuel Martin-Fonseca, Francisco Rivas, Fernando J Reyes-Zurita, Marta Medina-O'Donnell, Antonio Martinez, Andres Garcia-Granados, Jose A Lupiañez, Fernando Albericio. Semi-synthesis of acylated triterpenes from olive-oil industry wastes for the development of anticancer and anti-HIV agents. European journal of medicinal chemistry. 2014 Mar; 74(?):278-301. doi: 10.1016/j.ejmech.2013.12.049. [PMID: 24480359]
Bianka Siewert, René Csuk. Membrane damaging activity of a maslinic acid analog. European journal of medicinal chemistry. 2014 Mar; 74(?):1-6. doi: 10.1016/j.ejmech.2013.12.031. [PMID: 24440377]
Bo Zhai, Julie Clark, Taotao Ling, Michele Connelly, Fabricio Medina-Bolivar, Fatima Rivas. Antimalarial evaluation of the chemical constituents of hairy root culture of Bixa orellana L. Molecules (Basel, Switzerland). 2014 Jan; 19(1):756-66. doi: 10.3390/molecules19010756. [PMID: 24406786]
Hong-Min Wang, Qun-Fang Liu, Yi-Wu Zhao, Shuang-Zhu Liu, Zhen-Hua Chen, Ru-Jun Zhang, Zhen-Zhong Wang, Wei Xiao, Wei-Min Zhao. Four new triterpenoids isolated from the resin of Garcinia hanburyi. Journal of Asian natural products research. 2014 Jan; 16(1):20-8. doi: 10.1080/10286020.2013.875012. [PMID: 24392659]
Marta Sánchez-González, Glòria Lozano-Mena, M Emília Juan, Andrés García-Granados, Joana M Planas. Liquid chromatography-mass spectrometry determination in plasma of maslinic acid, a bioactive compound from Olea europaea L. Food chemistry. 2013 Dec; 141(4):4375-81. doi: 10.1016/j.foodchem.2013.07.023. [PMID: 23993628]
Marta Sánchez-González, Glòria Lozano-Mena, M Emília Juan, Andrés García-Granados, Joana M Planas. Assessment of the safety of maslinic acid, a bioactive compound from Olea europaea L. Molecular nutrition & food research. 2013 Feb; 57(2):339-46. doi: 10.1002/mnfr.201200481. [PMID: 23175023]
Augusta Caligiani, Giulia Malavasi, Gerardo Palla, Angela Marseglia, Massimiliano Tognolini, Renato Bruni. A simple GC-MS method for the screening of betulinic, corosolic, maslinic, oleanolic and ursolic acid contents in commercial botanicals used as food supplement ingredients. Food chemistry. 2013 Jan; 136(2):735-41. doi: 10.1016/j.foodchem.2012.08.011. [PMID: 23122121]
Glòria Lozano-Mena, M Emília Juan, Andrés García-Granados, Joana M Planas. Determination of maslinic acid, a pentacyclic triterpene from olives, in rat plasma by high-performance liquid chromatography. Journal of agricultural and food chemistry. 2012 Oct; 60(41):10220-5. doi: 10.1021/jf3023996. [PMID: 23003682]
Vlasios Goulas, George A Manganaris. Towards an efficient protocol for the determination of triterpenic acids in olive fruit: a comparative study of drying and extraction methods. Phytochemical analysis : PCA. 2012 Sep; 23(5):444-9. doi: 10.1002/pca.1378. [PMID: 22213569]
Mei-Chin Yin, Ming-Cheng Lin, Mei-Chin Mong, Chia-Yu Lin. Bioavailability, distribution, and antioxidative effects of selected triterpenes in mice. Journal of agricultural and food chemistry. 2012 Aug; 60(31):7697-701. doi: 10.1021/jf302529x. [PMID: 22816768]
Althaf Hussain Shaik, S N Rasool, M Abdul Kareem, G Saayi Krushna, P Mohammad Akhtar, Kodidhela Lakshmi Devi. Maslinic acid protects against isoproterenol-induced cardiotoxicity in albino Wistar rats. Journal of medicinal food. 2012 Aug; 15(8):741-6. doi: 10.1089/jmf.2012.2191. [PMID: 22846081]
José M Lou-Bonafonte, Carmen Arnal, María A Navarro, Jesús Osada. Efficacy of bioactive compounds from extra virgin olive oil to modulate atherosclerosis development. Molecular nutrition & food research. 2012 Jul; 56(7):1043-57. doi: 10.1002/mnfr.201100668. [PMID: 22760979]
Jiayi Tao, Weishuo Fang. [Chemical constituents from Sambucus chinensis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2012 May; 37(10):1399-401. doi: 10.4268/cjcmm20121011. [PMID: 22860449]
M Gowri Ponnapalli, S Ch V A Rao Annam, Saidulu Ravirala, Sushma Sukki, Madhu Ankireddy, V Raju Tuniki. Unusual isomeric corniculatolides from mangrove, Aegiceras corniculatum. Journal of natural products. 2012 Feb; 75(2):275-9. doi: 10.1021/np200789s. [PMID: 22316191]
Naïm Stiti, Marie-Andrée Hartmann. Nonsterol Triterpenoids as Major Constituents of Olea europaea. Journal of lipids. 2012; 2012(?):476595. doi: 10.1155/2012/476595. [PMID: 22523691]
Hala I Al-Jaber, Khadeja K Abrouni, Mahmuod A Al-Qudah, Musa H Abu Zarga. New terpenes from Salvia palaestina Benth. and Salvia syriaca L. growing wild in Jordan. Journal of Asian natural products research. 2012; 14(7):618-25. doi: 10.1080/10286020.2012.682151. [PMID: 22574636]
Chen-Chen Zhu, Li Gao, Zhong-Xiang Zhao, Chao-Zhan Lin. Triterpenes from Callicarpa integerrima Champ. Yao xue xue bao = Acta pharmaceutica Sinica. 2012 Jan; 47(1):77-83. doi: ". [PMID: 22493809]
Sheng Guo, Jin-ao Duan, Yuping Tang, Yefei Qian, Jinlong Zhao, Dawei Qian, Shulan Su, Erxin Shang. Simultaneous qualitative and quantitative analysis of triterpenic acids, saponins and flavonoids in the leaves of two Ziziphus species by HPLC-PDA-MS/ELSD. Journal of pharmaceutical and biomedical analysis. 2011 Sep; 56(2):264-70. doi: 10.1016/j.jpba.2011.05.025. [PMID: 21665400]
Fuqiang Jiang, Xuemei Zhang, Yunbao Ma, Chang'an Geng, Zhiyong Jiang, Jijun Chen. [Chemical constituents of Swertia hispidicalyx]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2011 Aug; 36(16):2215-8. doi: . [PMID: 22097333]
Hongbo Zhou, Feng Wang, Zhijian Fang. [Study on triterpenes from Solanum torvum]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2011 Aug; 36(15):2096-8. doi: 10.4268/cjcmm20111518. [PMID: 22066447]
Jun Liu, Hongbin Sun, Jing Shang, Yuanyuan Yong, Luyong Zhang. Effect of olive pomace extracts on hyperlipidaemia. Natural product research. 2011 Jul; 25(12):1190-4. doi: 10.1080/14786419.2010.521750. [PMID: 21740285]
Yuexia Wu, Fan Ye, Wei Zhang, Jicheng Li, Na Liu. [Chemical constituents about the stem of Rabdosia excisa]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2011 Jul; 36(13):1772-5. doi: 10.4268/cjcmm20111317. [PMID: 22032142]
Ivone Lucia Acebey-Castellon, Laurence Voutquenne-Nazabadioko, Huong Doan Thi Mai, Nathalie Roseau, Naima Bouthagane, Dima Muhammad, Elisabeth Le Magrex Debar, Sophie C Gangloff, Marc Litaudon, Thierry Sevenet, Nguyen Van Hung, Catherine Lavaud. Triterpenoid saponins from Symplocos lancifolia. Journal of natural products. 2011 Feb; 74(2):163-8. doi: 10.1021/np100502y. [PMID: 21288041]
Eunkyung Kim, Arlene Sy-Cordero, Tyler N Graf, Scott J Brantley, Mary F Paine, Nicholas H Oberlies. Isolation and identification of intestinal CYP3A inhibitors from cranberry (Vaccinium macrocarpon) using human intestinal microsomes. Planta medica. 2011 Feb; 77(3):265-70. doi: 10.1055/s-0030-1250259. [PMID: 20717876]
Yisong Qian, Teng Guan, Xuzhen Tang, Longfei Huang, Menghao Huang, Yunman Li, Hongbin Sun, Rong Yu, Fan Zhang. Astrocytic glutamate transporter-dependent neuroprotection against glutamate toxicity: an in vitro study of maslinic acid. European journal of pharmacology. 2011 Jan; 651(1-3):59-65. doi: 10.1016/j.ejphar.2010.10.095. [PMID: 21118675]
Yosra Allouche, Fernando Warleta, María Campos, Cristina Sánchez-Quesada, Marino Uceda, Gabriel Beltrán, José Juan Gaforio. Antioxidant, antiproliferative, and pro-apoptotic capacities of pentacyclic triterpenes found in the skin of olives on MCF-7 human breast cancer cells and their effects on DNA damage. Journal of agricultural and food chemistry. 2011 Jan; 59(1):121-30. doi: 10.1021/jf102319y. [PMID: 21142067]
Alain Bertrand Dongmo, Anatole Guy Blaise Azebaze, Flaure Metchi Donfack, Théophile Dimo, Pepin Alango Nkeng-Efouet, Krishna Prasad Devkota, Bruno Sontia, Hildebert Wagner, Norbert Sewald, Wolfgang Vierling. Pentacyclic triterpenoids and ceramide mediate the vasorelaxant activity of Vitex cienkowskii via involvement of NO/cGMP pathway in isolated rat aortic rings. Journal of ethnopharmacology. 2011 Jan; 133(1):204-12. doi: 10.1016/j.jep.2010.09.033. [PMID: 20920567]