Cetyl palmitate (BioDeep_00000009601)

Main id: BioDeep_00000630013

 

human metabolite blood metabolite natural product


代谢物信息卡片


Fatty acids, C16-18, C12-18-alkyl esters

化学式: C32H64O2 (480.4906044)
中文名称: C16-18 脂肪酸 C12-18 烷醇酯, 十六酸十六酯
谱图信息: 最多检出来源 Homo sapiens(blood) 95.24%

分子结构信息

SMILES: CCCCCCCCCCCCCCCC(OCCCCCCCCCCCCCCCC)=O
InChI: InChI=1S/C32H64O2/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-34-32(33)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h3-31H2,1-2H3

描述信息

Ceryl palmitate, also known as hexadecanyl hexadecanoate or hexadecanoic acid, hexadecyl ester, is a member of the class of compounds known as wax monoesters. Wax monoesters are waxes bearing an ester group at exactly one position. Thus, ceryl palmitate is considered to be a fatty ester lipid molecule. Ceryl palmitate is practically insoluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). Ceryl palmitate can be found in loquat and opium poppy, which makes ceryl palmitate a potential biomarker for the consumption of these food products.

同义名列表

23 个代谢物同义名

Fatty acids, C16-18, C12-18-alkyl esters; Hexadecanoic acid, hexadecyl ester; Palmitic acid, hexadecyl ester; Hexadecanoate, hexadecyl ester; N-Hexadecyl hexadecanoic acid; Hexadecanyl hexadecanoic acid; Palmitic acid palmityl ester; N-Hexadecanyl palmitic acid; Palmitic acid, cetyl ester; N-Hexadecyl hexadecanoate; hexadecanyl hexadecanoate; 1-hexadecyl hexadecanoate; Palmitate palmityl ester; N-Hexadecanyl palmitate; hexadecyl hexadecanoate; Palmitate, cetyl ester; Cetyl palmitic acid; Ceryl palmitic acid; Palmityl palmitate; Cetyl palmitate; Ceryl palmitate; WE(16:0/16:0); WE 32:0



数据库引用编号

19 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(2)

BioCyc(0)

PlantCyc(0)

代谢反应

62 个相关的代谢反应过程信息。

Reactome(62)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

9 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Rita M Pinto, Claudia Monteiro, Sofia A Costa Lima, Susana Casal, Patrick Van Dijck, M Cristina L Martins, Cláudia Nunes, Salette Reis. N-Acetyl-l-cysteine-Loaded Nanosystems as a Promising Therapeutic Approach Toward the Eradication of Pseudomonas aeruginosa Biofilms. ACS applied materials & interfaces. 2021 Sep; 13(36):42329-42343. doi: 10.1021/acsami.1c05124. [PMID: 34464076]
  • Ilaria Arduino, Zehua Liu, Antti Rahikkala, Patrícia Figueiredo, Alexandra Correia, Annalisa Cutrignelli, Nunzio Denora, Hélder A Santos. Preparation of cetyl palmitate-based PEGylated solid lipid nanoparticles by microfluidic technique. Acta biomaterialia. 2021 02; 121(?):566-578. doi: 10.1016/j.actbio.2020.12.024. [PMID: 33326887]
  • Eliana B Souto, Slavomira Doktorovova, Aleksandra Zielinska, Amélia M Silva. Key production parameters for the development of solid lipid nanoparticles by high shear homogenization. Pharmaceutical development and technology. 2019 Nov; 24(9):1181-1185. doi: 10.1080/10837450.2019.1647235. [PMID: 31354002]
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  • Warangkana Pornputtapitak, Jaturavit Pantakitcharoenkul, Veerawat Teeranachaideekul, Kitiphat Sinthiptharakoon, Chaweewan Sapcharoenkun, Benchaporn Meemuk. Effect of Oil Content on Physiochemical Characteristics of γ-Oryzanol-Loaded Nanostructured Lipid Carriers. Journal of oleo science. 2019 Aug; 68(8):699-707. doi: 10.5650/jos.ess18127. [PMID: 31292337]
  • Hery Mitsutake, Lígia N M Ribeiro, Gustavo H Rodrigues da Silva, Simone R Castro, Eneida de Paula, Ronei J Poppi, Márcia C Breitkreitz. Evaluation of miscibility and polymorphism of synthetic and natural lipids for nanostructured lipid carrier (NLC) formulations by Raman mapping and multivariate curve resolution (MCR). European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2019 Jul; 135(?):51-59. doi: 10.1016/j.ejps.2019.05.002. [PMID: 31071439]
  • Mariana Domingues Bianchin, Sílvia Maria Borowicz, Gabriella da Rosa Monte Machado, Bruna Pippi, Sílvia Stanisçuaski Guterres, Adriana Raffin Pohlmann, Alexandre Meneghello Fuentefria, Irene Clemes Külkamp-Guerreiro. Lipid core nanoparticles as a broad strategy to reverse fluconazole resistance in multiple Candida species. Colloids and surfaces. B, Biointerfaces. 2019 Mar; 175(?):523-529. doi: 10.1016/j.colsurfb.2018.12.011. [PMID: 30579053]
  • Hery Mitsutake, Simone R Castro, Eneida de Paula, Ronei J Poppi, Douglas N Rutledge, Márcia C Breitkreitz. Comparison of different chemometric methods to extract chemical and physical information from Raman images of homogeneous and heterogeneous semi-solid pharmaceutical formulations. International journal of pharmaceutics. 2018 Dec; 552(1-2):119-129. doi: 10.1016/j.ijpharm.2018.09.058. [PMID: 30266516]
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  • Maryam Ghadiri, Shohreh Fatemi, Alireza Vatanara, Delaram Doroud, Abdolhossein Rouholamini Najafabadi, Majid Darabi, Amir Abbas Rahimi. Loading hydrophilic drug in solid lipid media as nanoparticles: statistical modeling of entrapment efficiency and particle size. International journal of pharmaceutics. 2012 Mar; 424(1-2):128-37. doi: 10.1016/j.ijpharm.2011.12.037. [PMID: 22227603]
  • Kuo-Sheng Liu, Chih-Jen Wen, Tzu-Chen Yen, K C Sung, Ming-Chuan Ku, Jhi-Joung Wang, Jia-You Fang. Combined strategies of apomorphine diester prodrugs and nanostructured lipid carriers for efficient brain targeting. Nanotechnology. 2012 Mar; 23(9):095103. doi: 10.1088/0957-4484/23/9/095103. [PMID: 22327243]
  • C Carbone, B Tomasello, B Ruozi, M Renis, G Puglisi. Preparation and optimization of PIT solid lipid nanoparticles via statistical factorial design. European journal of medicinal chemistry. 2012 Mar; 49(?):110-7. doi: 10.1016/j.ejmech.2012.01.001. [PMID: 22244589]
  • Akhayacatra Chinsriwongkul, Ponwanit Chareanputtakhun, Tanasait Ngawhirunpat, Theerasak Rojanarata, Warisada Sila-on, Uracha Ruktanonchai, Praneet Opanasopit. Nanostructured lipid carriers (NLC) for parenteral delivery of an anticancer drug. AAPS PharmSciTech. 2012 Mar; 13(1):150-8. doi: 10.1208/s12249-011-9733-8. [PMID: 22167418]
  • R Witzleb, A Müllertz, V-R Kanikanti, H-J Hamann, P Kleinebudde. Dissolution of solid lipid extrudates in biorelevant media. International journal of pharmaceutics. 2012 Jan; 422(1-2):116-24. doi: 10.1016/j.ijpharm.2011.10.037. [PMID: 22044538]
  • Susana M Martins, Thierry Wendling, Virgínia M F Gonçalves, Bruno Sarmento, Domingos C Ferreira. Development and validation of a simple reversed-phase HPLC method for the determination of camptothecin in animal organs following administration in solid lipid nanoparticles. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2012 Jan; 880(1):100-7. doi: 10.1016/j.jchromb.2011.11.023. [PMID: 22153332]
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  • Patrícia Severino, Tatiana Andreani, Ana Sofia Macedo, Joana F Fangueiro, Maria Helena A Santana, Amélia M Silva, Eliana B Souto. Current State-of-Art and New Trends on Lipid Nanoparticles (SLN and NLC) for Oral Drug Delivery. Journal of drug delivery. 2012; 2012(?):750891. doi: 10.1155/2012/750891. [PMID: 22175030]
  • Jessica Carilli, Simon D Donner, Aaron C Hartmann. Historical temperature variability affects coral response to heat stress. PloS one. 2012; 7(3):e34418. doi: 10.1371/journal.pone.0034418. [PMID: 22479626]
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  • Delaram Doroud, Farnaz Zahedifard, Alireza Vatanara, Yasaman Taslimi, Rouholah Vahabpour, Fatemeh Torkashvand, Behrooz Vaziri, Abdolhossein Rouholamini Najafabadi, Sima Rafati. C-terminal domain deletion enhances the protective activity of cpa/cpb loaded solid lipid nanoparticles against Leishmania major in BALB/c mice. PLoS neglected tropical diseases. 2011 Jul; 5(7):e1236. doi: 10.1371/journal.pntd.0001236. [PMID: 21765963]
  • Mohamed Sellami, Imen Aissa, Fakher Frikha, Youssef Gargouri, Nabil Miled. Immobilized Rhizopus oryzae lipase catalyzed synthesis of palm stearin and cetyl alcohol wax esters: optimization by response surface methodology. BMC biotechnology. 2011 Jun; 11(?):68. doi: 10.1186/1472-6750-11-68. [PMID: 21682865]
  • D Doroud, F Zahedifard, A Vatanara, A R Najafabadi, S Rafati. Cysteine proteinase type I, encapsulated in solid lipid nanoparticles induces substantial protection against Leishmania major infection in C57BL/6 mice. Parasite immunology. 2011 Jun; 33(6):335-48. doi: 10.1111/j.1365-3024.2011.01289.x. [PMID: 21410716]
  • Lucia Montenegro, Agata Campisi, Maria Grazia Sarpietro, Claudia Carbone, Rosaria Acquaviva, Giuseppina Raciti, Giovanni Puglisi. In vitro evaluation of idebenone-loaded solid lipid nanoparticles for drug delivery to the brain. Drug development and industrial pharmacy. 2011 Jun; 37(6):737-46. doi: 10.3109/03639045.2010.539231. [PMID: 21204752]
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  • Rui Yang, Renchao Gao, Fang Li, Haibing He, Xing Tang. The influence of lipid characteristics on the formation, in vitro release, and in vivo absorption of protein-loaded SLN prepared by the double emulsion process. Drug development and industrial pharmacy. 2011 Feb; 37(2):139-48. doi: 10.3109/03639045.2010.497151. [PMID: 20578879]
  • Sin Man Lam, Louis Tong, Siew Sian Yong, Bowen Li, Shyam S Chaurasia, Guanghou Shui, Markus R Wenk. Meibum lipid composition in Asians with dry eye disease. PloS one. 2011; 6(10):e24339. doi: 10.1371/journal.pone.0024339. [PMID: 22043274]
  • Yosra S R Elnaggar, Magda A El-Massik, Ossama Y Abdallah. Fabrication, appraisal, and transdermal permeation of sildenafil citrate-loaded nanostructured lipid carriers versus solid lipid nanoparticles. International journal of nanomedicine. 2011; 6(?):3195-205. doi: 10.2147/ijn.s25825. [PMID: 22238508]
  • Sharareh Eskandari, Jaleh Varshosaz, Mohsen Minaiyan, Majid Tabbakhian. Brain delivery of valproic acid via intranasal administration of nanostructured lipid carriers: in vivo pharmacodynamic studies using rat electroshock model. International journal of nanomedicine. 2011; 6(?):363-71. doi: 10.2147/ijn.s15881. [PMID: 21499426]
  • Effat Sadat Farboud, Saman Ahmad Nasrollahi, Zahra Tabbakhi. Novel formulation and evaluation of a Q10-loaded solid lipid nanoparticle cream: in vitro and in vivo studies. International journal of nanomedicine. 2011; 6(?):611-7. doi: 10.2147/ijn.s16815. [PMID: 21674018]
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