Cetyl palmitate (BioDeep_00000009601)

Main id: BioDeep_00000630013

 

human metabolite blood metabolite natural product


代谢物信息卡片


Fatty acids, C16-18, C12-18-alkyl esters

化学式: C32H64O2 (480.4906)
中文名称: C16-18 脂肪酸 C12-18 烷醇酯, 十六酸十六酯
谱图信息: 最多检出来源 Homo sapiens(blood) 55.08%

分子结构信息

SMILES: CCCCCCCCCCCCCCCC(OCCCCCCCCCCCCCCCC)=O
InChI: InChI=1S/C32H64O2/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-34-32(33)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h3-31H2,1-2H3

描述信息

Ceryl palmitate, also known as hexadecanyl hexadecanoate or hexadecanoic acid, hexadecyl ester, is a member of the class of compounds known as wax monoesters. Wax monoesters are waxes bearing an ester group at exactly one position. Thus, ceryl palmitate is considered to be a fatty ester lipid molecule. Ceryl palmitate is practically insoluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). Ceryl palmitate can be found in loquat and opium poppy, which makes ceryl palmitate a potential biomarker for the consumption of these food products.

同义名列表

23 个代谢物同义名

Fatty acids, C16-18, C12-18-alkyl esters; Hexadecanoic acid, hexadecyl ester; Palmitic acid, hexadecyl ester; Hexadecanoate, hexadecyl ester; N-Hexadecyl hexadecanoic acid; Hexadecanyl hexadecanoic acid; Palmitic acid palmityl ester; N-Hexadecanyl palmitic acid; Palmitic acid, cetyl ester; N-Hexadecyl hexadecanoate; hexadecanyl hexadecanoate; 1-hexadecyl hexadecanoate; Palmitate palmityl ester; N-Hexadecanyl palmitate; hexadecyl hexadecanoate; Palmitate, cetyl ester; Cetyl palmitic acid; Ceryl palmitic acid; Palmityl palmitate; Cetyl palmitate; Ceryl palmitate; WE(16:0/16:0); WE 32:0



数据库引用编号

19 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(2)

BioCyc(0)

PlantCyc(0)

代谢反应

62 个相关的代谢反应过程信息。

Reactome(62)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

9 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表
Cytoplasm 5 ABCB1, MTOR, PDGFRA, TYR, VEGFA
Peripheral membrane protein 1 MTOR
Endoplasmic reticulum membrane 3 MTOR, PDGFRA, SLN
Nucleus 4 BEND3, MTOR, PDGFRA, VEGFA
cytosol 2 LIPE, MTOR
dendrite 1 MTOR
phagocytic vesicle 1 MTOR
centrosome 1 SLC16A1
nucleoplasm 3 BEND3, MTOR, PDGFRA
Cell membrane 4 ABCB1, LIPE, PDGFRA, SLC16A1
Cytoplasmic side 1 MTOR
Multi-pass membrane protein 2 ABCB1, SLC16A1
Golgi apparatus membrane 1 MTOR
Synapse 1 SLC16A1
cell junction 2 PDGFRA, SLC16A1
cell surface 2 ABCB1, VEGFA
Golgi apparatus 2 PDGFRA, VEGFA
Golgi membrane 2 INS, MTOR
lysosomal membrane 1 MTOR
Cytoplasm, cytosol 1 LIPE
Lysosome 2 MTOR, TYR
plasma membrane 4 ABCB1, PDGFRA, PRSS27, SLC16A1
Membrane 7 ABCB1, LIPE, MTOR, PDGFRA, SLC16A1, SLN, VEGFA
apical plasma membrane 2 ABCB1, SLC16A1
basolateral plasma membrane 1 SLC16A1
caveola 1 LIPE
extracellular exosome 2 ABCB1, SLC16A1
Lysosome membrane 1 MTOR
endoplasmic reticulum 1 VEGFA
extracellular space 5 IL4, IL6, INS, PNLIP, VEGFA
perinuclear region of cytoplasm 1 TYR
adherens junction 1 VEGFA
protein-containing complex 1 PDGFRA
intracellular membrane-bounded organelle 2 SLC16A1, TYR
Microsome membrane 1 MTOR
TORC1 complex 1 MTOR
TORC2 complex 1 MTOR
Single-pass type I membrane protein 2 PDGFRA, TYR
Secreted 5 IL4, IL6, INS, PNLIP, VEGFA
extracellular region 6 IL4, IL6, INS, PNLIP, PRSS27, VEGFA
Mitochondrion outer membrane 1 MTOR
Single-pass membrane protein 1 SLN
mitochondrial outer membrane 1 MTOR
Cell projection, cilium 1 PDGFRA
external side of plasma membrane 1 PDGFRA
Secreted, extracellular space, extracellular matrix 1 VEGFA
nucleolus 1 BEND3
Melanosome membrane 1 TYR
Golgi-associated vesicle 1 TYR
Apical cell membrane 2 ABCB1, SLC16A1
heterochromatin 1 BEND3
extracellular matrix 1 VEGFA
sarcoplasmic reticulum 1 SLN
Nucleus, PML body 1 MTOR
PML body 1 MTOR
secretory granule 1 VEGFA
lateral plasma membrane 1 SLC16A1
receptor complex 1 PDGFRA
cilium 1 PDGFRA
Nucleus, nucleolus 1 BEND3
Basolateral cell membrane 1 SLC16A1
nuclear envelope 1 MTOR
Endomembrane system 1 MTOR
endosome lumen 1 INS
microvillus 1 PDGFRA
Lipid droplet 1 LIPE
Membrane, caveola 1 LIPE
Melanosome 1 TYR
basal plasma membrane 1 SLC16A1
secretory granule lumen 1 INS
Golgi lumen 1 INS
endoplasmic reticulum lumen 2 IL6, INS
platelet alpha granule lumen 1 VEGFA
transport vesicle 1 INS
Sarcoplasmic reticulum membrane 1 SLN
Endoplasmic reticulum-Golgi intermediate compartment membrane 1 INS
external side of apical plasma membrane 1 ABCB1
Cytoplasmic vesicle, phagosome 1 MTOR
interleukin-6 receptor complex 1 IL6
[N-VEGF]: Cytoplasm 1 VEGFA
[VEGFA]: Secreted 1 VEGFA
[Isoform L-VEGF189]: Endoplasmic reticulum 1 VEGFA
[Isoform VEGF121]: Secreted 1 VEGFA
[Isoform VEGF165]: Secreted 1 VEGFA
VEGF-A complex 1 VEGFA


文献列表

  • Rita M Pinto, Claudia Monteiro, Sofia A Costa Lima, Susana Casal, Patrick Van Dijck, M Cristina L Martins, Cláudia Nunes, Salette Reis. N-Acetyl-l-cysteine-Loaded Nanosystems as a Promising Therapeutic Approach Toward the Eradication of Pseudomonas aeruginosa Biofilms. ACS applied materials & interfaces. 2021 Sep; 13(36):42329-42343. doi: 10.1021/acsami.1c05124. [PMID: 34464076]
  • Ilaria Arduino, Zehua Liu, Antti Rahikkala, Patrícia Figueiredo, Alexandra Correia, Annalisa Cutrignelli, Nunzio Denora, Hélder A Santos. Preparation of cetyl palmitate-based PEGylated solid lipid nanoparticles by microfluidic technique. Acta biomaterialia. 2021 02; 121(?):566-578. doi: 10.1016/j.actbio.2020.12.024. [PMID: 33326887]
  • Eliana B Souto, Slavomira Doktorovova, Aleksandra Zielinska, Amélia M Silva. Key production parameters for the development of solid lipid nanoparticles by high shear homogenization. Pharmaceutical development and technology. 2019 Nov; 24(9):1181-1185. doi: 10.1080/10837450.2019.1647235. [PMID: 31354002]
  • Luciana N Andrade, Daniele M L Oliveira, Marco V Chaud, Thais F R Alves, Marcelo Nery, Classius F da Silva, Joyce K C Gonsalves, Rogéria S Nunes, Cristiane B Corrêa, Ricardo G Amaral, Elena Sanchez-Lopez, Eliana B Souto, Patrícia Severino. Praziquantel-Solid Lipid Nanoparticles Produced by Supercritical Carbon Dioxide Extraction: Physicochemical Characterization, Release Profile, and Cytotoxicity. Molecules (Basel, Switzerland). 2019 Oct; 24(21):. doi: 10.3390/molecules24213881. [PMID: 31661906]
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  • Mariana Domingues Bianchin, Sílvia Maria Borowicz, Gabriella da Rosa Monte Machado, Bruna Pippi, Sílvia Stanisçuaski Guterres, Adriana Raffin Pohlmann, Alexandre Meneghello Fuentefria, Irene Clemes Külkamp-Guerreiro. Lipid core nanoparticles as a broad strategy to reverse fluconazole resistance in multiple Candida species. Colloids and surfaces. B, Biointerfaces. 2019 Mar; 175(?):523-529. doi: 10.1016/j.colsurfb.2018.12.011. [PMID: 30579053]
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  • Mohamed Sellami, Imen Aissa, Fakher Frikha, Youssef Gargouri, Nabil Miled. Immobilized Rhizopus oryzae lipase catalyzed synthesis of palm stearin and cetyl alcohol wax esters: optimization by response surface methodology. BMC biotechnology. 2011 Jun; 11(?):68. doi: 10.1186/1472-6750-11-68. [PMID: 21682865]
  • D Doroud, F Zahedifard, A Vatanara, A R Najafabadi, S Rafati. Cysteine proteinase type I, encapsulated in solid lipid nanoparticles induces substantial protection against Leishmania major infection in C57BL/6 mice. Parasite immunology. 2011 Jun; 33(6):335-48. doi: 10.1111/j.1365-3024.2011.01289.x. [PMID: 21410716]
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  • Sharareh Eskandari, Jaleh Varshosaz, Mohsen Minaiyan, Majid Tabbakhian. Brain delivery of valproic acid via intranasal administration of nanostructured lipid carriers: in vivo pharmacodynamic studies using rat electroshock model. International journal of nanomedicine. 2011; 6(?):363-71. doi: 10.2147/ijn.s15881. [PMID: 21499426]
  • Effat Sadat Farboud, Saman Ahmad Nasrollahi, Zahra Tabbakhi. Novel formulation and evaluation of a Q10-loaded solid lipid nanoparticle cream: in vitro and in vivo studies. International journal of nanomedicine. 2011; 6(?):611-7. doi: 10.2147/ijn.s16815. [PMID: 21674018]
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