3-Hydroxyflavanone (BioDeep_00000859165)

代谢物信息卡片

2,3-dihydroflavon-3-ol

化学式: C15H12O3 (240.0786402)
中文名称: 3-羟基黄酮, 3-羟基黄烷酮
谱图信息: 最多检出来源 Homo sapiens(blood) 44.76%

分子结构信息

SMILES: C1=CC=C(C=C1)C2C(C(=O)C3=CC=CC=C3O2)O
InChI: InChI=1S/C15H12O3/c16-13-11-8-4-5-9-12(11)18-15(14(13)17)10-6-2-1-3-7-10/h1-9,14-15,17H

描述信息

The simplest member of the class of dihydroflavonols that is flavanone with a hydroxy substituent at the 3-position.
A monohydroxyflavanone in which the hydroxy group is located at position 3.

同义名列表

3 个代谢物同义名

2,3-dihydroflavon-3-ol; 3-Hydroxyflavanone; 3-hydroxy flavanone

数据库引用编号

15 个数据库交叉引用编号

ChEBI: CHEBI:48040
ChEBI: CHEBI:48039
ChEBI: CHEBI:48022
KEGG: C15204
KEGGdrug: D90992
PubChem: 147806
PubChem: 3534982
ChEMBL: CHEMBL485021
CAS: 124191-32-8
CAS: 1621-55-2
CAS: 92496-65-6
MetaboLights: MTBLC48040
MetaboLights: MTBLC48022
PubChem: 17396201
NIKKAJI: J1.257.765F

分类词条

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

33 个相关的物种来源信息

178749 - Acacia acuminata: 10.1016/S0031-9422(00)85959-2
205021 - Acacia aneura: 10.1016/S0031-9422(00)85959-2
138511 - Acacia aulacocarpa: 10.1016/S0031-9422(00)85959-2
205027 - Acacia auriculiformis: 10.1016/S0031-9422(00)85959-2
1174742 - Acacia binervia: 10.1016/S0031-9422(00)85959-2
1173640 - Acacia cheelii: 10.1016/S0031-9422(00)85959-2
1174758 - Acacia complanata: 10.1016/S0031-9422(00)85959-2
1173642 - Acacia concurrens: 10.1016/S0031-9422(00)85959-2
694541 - Acacia doratoxylon: 10.1016/S0031-9422(00)85959-2
1174788 - Acacia excelsa: 10.1016/S0031-9422(00)85959-2
866001 - Acacia floribunda: 10.1016/S0031-9422(00)85959-2
669369 - Acacia harpophylla: 10.1016/S0031-9422(00)85959-2
1120455 - Acacia holosericea: 10.1016/S0031-9422(00)85959-2
1120457 - Acacia implexa: 10.1016/S0031-9422(00)85959-2
139010 - Acacia longifolia: 10.1016/S0031-9422(00)85959-2
795978 - Acacia maidenii: 10.1016/S0031-9422(00)85959-2
224085 - Acacia mangium: 10.1016/S0031-9422(00)85959-2
138028 - Acacia melanoxylon: 10.1016/S0031-9422(00)85959-2
866003 - Acacia obtusifolia: 10.1016/S0031-9422(00)85959-2
1173659 - Acacia omalophylla: 10.1016/S0031-9422(00)85959-2
866004 - Acacia orites: 10.1016/S0031-9422(00)85959-2
139013 - Acacia oswaldii: 10.1016/S0031-9422(00)85959-2
1173660 - Acacia pendula: 10.1016/S0031-9422(00)85959-2
1174874 - Acacia pubifolia: 10.1016/S0031-9422(00)85959-2
1280823 - Acacia pycnostachya: 10.1016/S0031-9422(00)85959-2
1050817 - Acacia retinodes: 10.1016/S0031-9422(00)85959-2
694556 - Acacia rigens: 10.1016/S0031-9422(00)85959-2
1378425 - Acacia trineura: 10.1016/S0031-9422(00)85959-2
1120475 - Acacia verniciflua: 10.1016/S0031-9422(00)85959-2
649199 - Astragalus membranaceus: 10.1093/CHROMSCI/BMT016
119829 - Astragalus mongholicus: 10.1093/CHROMSCI/BMT016
3570 - Dianthus caryophyllus: 10.1515/ZNC-1992-7-811
99292 - Hovenia dulcis: 10.1016/J.FOODCHEM.2012.09.098

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

文献列表

Huixiao Hong, William S Branham, Hui Wen Ng, Carrie L Moland, Stacey L Dial, Hong Fang, Roger Perkins, Daniel Sheehan, Weida Tong. Human sex hormone-binding globulin binding affinities of 125 structurally diverse chemicals and comparison with their binding to androgen receptor, estrogen receptor, and α-fetoprotein. Toxicological sciences : an official journal of the Society of Toxicology. 2015 Feb; 143(2):333-48. doi: 10.1093/toxsci/kfu231. [PMID: 25349334]
Huixiao Hong, William S Branham, Stacey L Dial, Carrie L Moland, Hong Fang, Jie Shen, Roger Perkins, Daniel Sheehan, Weida Tong. Rat α-Fetoprotein binding affinities of a large set of structurally diverse chemicals elucidated the relationships between structures and binding affinities. Chemical research in toxicology. 2012 Nov; 25(11):2553-66. doi: 10.1021/tx3003406. [PMID: 23013281]
Sang Jun Uhm, Mukesh Kumar Gupta, Ziban Chandra Das, Nam-Hyung Kim, Hoon Taek Lee. 3-Hydroxyflavone improves the in vitro development of cloned porcine embryos by inhibiting ROS production. Cellular reprogramming. 2011 Oct; 13(5):441-9. doi: 10.1089/cell.2011.0017. [PMID: 21740267]
Sule Oncul, Andrey S Klymchenko, Oleksandr A Kucherak, Alexander P Demchenko, Sophie Martin, Monique Dontenwill, Youri Arntz, Pascal Didier, Guy Duportail, Yves Mély. Liquid ordered phase in cell membranes evidenced by a hydration-sensitive probe: effects of cholesterol depletion and apoptosis. Biochimica et biophysica acta. 2010 Jul; 1798(7):1436-43. doi: 10.1016/j.bbamem.2010.01.013. [PMID: 20100458]
Adriana del V Pacciaroni, María de los Angeles Gette, Marcos Derita, Luis Ariza-Espinar, Roberto R Gil, Susana A Zacchino, Gloria L Silva. Antifungal activity of Heterothalamus alienus metabolites. Phytotherapy research : PTR. 2008 Apr; 22(4):524-8. doi: 10.1002/ptr.2380. [PMID: 18386258]
Yuji Sawada, Kengo Kinoshita, Tomoyoshi Akashi, Toshio Aoki, Shin-Ichi Ayabe. Key amino acid residues required for aryl migration catalysed by the cytochrome P450 2-hydroxyisoflavanone synthase. The Plant journal : for cell and molecular biology. 2002 Sep; 31(5):555-64. doi: 10.1046/j.1365-313x.2002.01378.x. [PMID: 12207646]