Hexoprenaline (BioDeep_00000858894)
代谢物信息卡片
化学式: C22H32N2O6 (420.226)
中文名称: 海索那林
谱图信息:
最多检出来源 () %
分子结构信息
SMILES: C1=CC(=C(C=C1C(CNCCCCCCNCC(C2=CC(=C(C=C2)O)O)O)O)O)O
InChI: InChI=1S/C22H32N2O6/c25-17-7-5-15(11-19(17)27)21(29)13-23-9-3-1-2-4-10-24-14-22(30)16-6-8-18(26)20(28)12-16/h5-8,11-12,21-30H,1-4,9-10,13-14H2
描述信息
R - Respiratory system > R03 - Drugs for obstructive airway diseases > R03C - Adrenergics for systemic use > R03CC - Selective beta-2-adrenoreceptor agonists
R - Respiratory system > R03 - Drugs for obstructive airway diseases > R03A - Adrenergics, inhalants > R03AC - Selective beta-2-adrenoreceptor agonists
D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D001993 - Bronchodilator Agents
C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C87053 - Adrenergic Agonist
D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists
D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents
D012102 - Reproductive Control Agents > D015149 - Tocolytic Agents
同义名列表
2 个代谢物同义名
数据库引用编号
6 个数据库交叉引用编号
- KEGGdrug: D08039
- PubChem: 3609
- DrugBank: DB08957
- ChEMBL: CHEMBL1589896
- MeSH: Hexoprenaline
- CAS: 3215-70-1
分类词条
相关代谢途径
Reactome()
BioCyc()
PlantCyc()
代谢反应
个相关的代谢反应过程信息。
Reactome()
BioCyc()
WikiPathways()
Plant Reactome()
INOH()
PlantCyc()
COVID-19 Disease Map()
PathBank()
PharmGKB()
个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Daniel J Warner, Hongming Chen, Louis-David Cantin, J Gerry Kenna, Simone Stahl, Clare L Walker, Tobias Noeske. Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Drug metabolism and disposition: the biological fate of chemicals.
2012 Dec; 40(12):2332-41. doi:
10.1124/dmd.112.047068. [PMID: 22961681] - Rasha M El-Nashar. Flow injection potentiometric assay of hexoprenaline in its pure state, pharmaceutical preparations, and biological samples.
Journal of automated methods & management in chemistry.
2008; 2008(?):586310. doi:
10.1155/2008/586310. [PMID: 18483573] - Iu A Pytel', D M Rapoport, V I Rudenko, A V Chaban. [beta 2-Adrenomimetics before and after extracorporeal lithotripsy].
Urologiia i nefrologiia.
1998 Sep; ?(5):3-6. doi:
. [PMID: 9820034] - P Bremner, C Burgess, G Purdie, R Beasley, J Crane. The extrapulmonary effects of inhaled hexoprenaline and salbutamol in healthy individuals.
European journal of clinical pharmacology.
1993; 45(1):37-9. doi:
10.1007/bf00315347. [PMID: 8405027] - N Vavra, P Sevelda, R Fitz, W Eppel, A R Fuchs, F Fuchs, P Husslein. [The significance of prostaglandin F2 alpha (PGFM)--and plasma oxytocin level in patients with premature labor].
Geburtshilfe und Frauenheilkunde.
1992 Aug; 52(8):475-8. doi:
10.1055/s-2007-1023792. [PMID: 1397943] - H H Bodemann, M Irmer, K J Schlüter, M Reininghaus, J Keul. Activation of sodium transport in human erythrocytes by beta-adrenoceptor stimulation in vivo.
European journal of applied physiology and occupational physiology.
1987; 56(4):375-80. doi:
10.1007/bf00417762. [PMID: 3040390] - W Lechner, G Daxenbichler. [Myoglobin behavior with hexoprenaline and beta blockade].
Zeitschrift fur Geburtshilfe und Perinatologie.
1984 Sep; 188(5):226-7. doi:
. [PMID: 6506836] - U Siekmann, L Heilmann, O E Brodde. [Maternal and fetal hemodynamics under simultaneous beta stimulation and beta1 blockade in a tocolysis model. Considerations on status of the neonatal beta receptor and transplacental passage of metoprolol].
Arzneimittel-Forschung.
1984; 34(9):1025-30. doi:
. [PMID: 6150714] - L Heilmann, U Siekmann, H Ludwig. [Hemodynamic changes during tocolysis with hexoprenaline and fenoterol].
Zeitschrift fur Geburtshilfe und Perinatologie.
1983 Jan; 187(1):11-6. doi:
. [PMID: 6682592] - M Haukkamaa, M Gummerus. Decrease of serum oestriol during intravenous hexoprenaline or salbutamol treatment.
British journal of obstetrics and gynaecology.
1982 Nov; 89(11):917-20. doi:
10.1111/j.1471-0528.1982.tb05057.x. [PMID: 7171499] - E Gitsch, K Philipp. Prevention of urological complications after radical operation of cervical carcinoma.
European journal of gynaecological oncology.
1982; 3(1):8-13. doi:
. [PMID: 6129138] - W Lechner, F Dienstl, W Poewe, G Daxenbichler. [Myoglobin increase during tocolysis (author's transl)].
Wiener klinische Wochenschrift.
1980 Jul; 92(14):502-5. doi:
. [PMID: 6933741] - R Shires, B I Joffe, L G Heding, H C Seftel. Metabolic studies in acute asthma before and after treatment.
British journal of diseases of the chest.
1979 Jan; 73(1):66-70. doi:
. [PMID: 435379] - J Lipshitz, A I Vinik. The effects of hexoprenaline, a beta 2-sympathomimetic drug, on maternal glucose, insulin, glucagon, and free fatty acid levels.
American journal of obstetrics and gynecology.
1978 Apr; 130(7):761-4. doi:
10.1016/0002-9378(78)90005-4. [PMID: 637098]
