plaunotol (BioDeep_00000858751)

Main id: BioDeep_00000009437

 

Volatile Flavor Compounds natural product


代谢物信息卡片


plaunotol

化学式: C20H34O2 (306.2558664)
中文名称: 谱劳诺托
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(=CCCC(=CCCC(=CCCC(=CCO)C)CO)C)C
InChI: InChI=1S/C20H34O2/c1-17(2)8-5-9-18(3)10-6-12-20(16-22)13-7-11-19(4)14-15-21/h8,10,13-14,21-22H,5-7,9,11-12,15-16H2,1-4H3/b18-10+,19-14+,20-13-

描述信息

C78276 - Agent Affecting Digestive System or Metabolism > C29701 - Anti-ulcer Agent
D005765 - Gastrointestinal Agents > D000897 - Anti-Ulcer Agents
D000890 - Anti-Infective Agents

同义名列表

2 个代谢物同义名

plaunotol; Plaunotol



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(1)

PlantCyc(1)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

17 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Siriluk Sintupachee, Nattaya Ngamrojanavanich, Worapan Sitthithaworn, Wanchai De-Eknamkul. Molecular cloning, bacterial expression and functional characterisation of cytochrome P450 monooxygenase, CYP97C27, and NADPH-cytochrome P450 reductase, CPR I, from Croton stellatopilosus Ohba. Plant science : an international journal of experimental plant biology. 2014 Dec; 229(?):131-141. doi: 10.1016/j.plantsci.2014.09.001. [PMID: 25443840]
  • Chatchai Chaotham, Songpol Chivapat, Anan Chaikitwattana, Wanchai De-Eknamkul. Acute and chronic oral toxicity of a partially purified plaunotol extract from Croton stellatopilosus Ohba. BioMed research international. 2013; 2013(?):303162. doi: 10.1155/2013/303162. [PMID: 24286075]
  • Prasob-orn Rinthong, Shu Zhu, Katsuko Komatsu, Suchart Chanama, Wanchai De-Eknamkul. Genetic variation of Croton stellatopilosus Ohba based on non-coding DNA sequences of ITS, trnK and trnL-F regions. Journal of natural medicines. 2011 Jul; 65(3-4):641-5. doi: 10.1007/s11418-011-0536-8. [PMID: 21499847]
  • Siribang-on Piboonniyom Khovidhunkit, Nadiya Yingsaman, Kongtawat Chairachvit, Rudee Surarit, Pornpoj Fuangtharnthip, Amorn Petsom. In vitro study of the effects of plaunotol on oral cell proliferation and wound healing. Journal of Asian natural products research. 2011 Feb; 13(2):149-59. doi: 10.1080/10286020.2010.546790. [PMID: 21279879]
  • Naoyuki Yoshikawa, Jun Yamada, Nelson H Tsuno, Yurai Okaji, Kazushige Kawai, Takeshi Tsuchiya, Satomi Yoneyama, Junichiro Tanaka, Yasutaka Shuno, Takeshi Nishikawa, Hirokazu Nagawa, Noriko Oshima, Koki Takahashi. Plaunotol and geranylgeraniol induce caspase-mediated apoptosis in colon cancer. The Journal of surgical research. 2009 May; 153(2):246-53. doi: 10.1016/j.jss.2008.04.021. [PMID: 18805546]
  • Juraithip Wungsintaweekul, Tanawan Sirisuntipong, Damrong Kongduang, Thanaisawan Losuphanporn, Anan Ounaroon, Pimpimon Tansakul, Wanchai De-Eknamkul. Transcription profiles analysis of genes encoding 1-deoxy-D-xylulose 5-phosphate synthase and 2C-methyl-D-erythritol 4-phosphate synthase in plaunotol biosynthesis from Croton stellatopilosus. Biological & pharmaceutical bulletin. 2008 May; 31(5):852-6. doi: 10.1248/bpb.31.852. [PMID: 18451506]
  • Jun Yamada, Kazushige Kawai, Nelson H Tsuno, Joji Kitayama, Takeshi Tsuchiya, Satomi Yoneyama, Masahiro Asakage, Yurai Okaji, Koki Takahashi, Hirokazu Nagawa. Plaunotol induces apoptosis of gastric cancer cells. Planta medica. 2007 Aug; 73(10):1068-73. doi: 10.1055/s-2007-981578. [PMID: 17691055]
  • Hai ying Fu, Yuki Yabe, Kayoko Asahi, Yujiro Hayashi, Hiroaki Murata, Hiroshi Eguchi, Masahiko Tsujii, Shingo Tsuji, Sunao Kawano. (2E,6Z,10E)-7-hydroxymethyl-3,11,15-trimethyl-2,6,10,14-hexadecatetraen-1-ol (Plaunotol) increases cyclooxygenase-2 expression via nuclear factor kappaB and cyclic AMP response element in rat gastric epithelial cells. European journal of pharmacology. 2005 Nov; 524(1-3):38-43. doi: 10.1016/j.ejphar.2005.09.044. [PMID: 16253229]
  • Yoshiji Ohta, Yoshio Kamiya, Yoichiro Imai, Tomiyasu Arisawa, Hiroshi Nakano. Plaunotol prevents the progression of acute gastric mucosal lesions induced by compound 48/80, a mast cell degranulator, in rats. Pharmacology. 2005 Jul; 74(4):182-92. doi: 10.1159/000085388. [PMID: 15855831]
  • H Tamura, H Tokushima, M Murakawa, O Matsumura, S Itoyama, S Sekine, H Hirose, T Mitarai, K Isoda. Eradication of Helicobacter pylori in patients with end-stage renal disease under dialysis treatment. American journal of kidney diseases : the official journal of the National Kidney Foundation. 1997 Jan; 29(1):86-90. doi: 10.1016/s0272-6386(97)90012-3. [PMID: 9002534]
  • K Murakami, T Fujioka, A Nishizono, J Nagai, M Tokieda, R Kodama, T Kubota, M Nasu. Atopic dermatitis successfully treated by eradication of Helicobacter pylori. Journal of gastroenterology. 1996 Nov; 31 Suppl 9(?):77-82. doi: . [PMID: 8959527]
  • H Tokushima, H Tamura, O Matsumura, M Murakawa, Y Itakura, S Itoyama, T Mitarai, K Isoda. [Eradication of Helicobacter pylori in patients with end-stage renal disease undergoing dialysis treatment]. Nihon Jinzo Gakkai shi. 1996 Aug; 38(8):349-55. doi: . [PMID: 8828354]
  • H Kaneko, T Mitsuma, H Nagai, M Harada, H Kotera, A Furusawa, K Morise. Effect of plaunotol on hypergastrinemia induced by long-term omeprazole administration in humans. Digestive diseases and sciences. 1995 Jan; 40(1):160-5. doi: 10.1007/bf02063960. [PMID: 7821104]
  • K Shiratori, S Watanabe, T Takeuchi. Role of endogenous prostaglandins in secretin- and plaunotol-induced inhibition of gastric acid secretion in the rat. The American journal of gastroenterology. 1993 Jan; 88(1):84-9. doi: . [PMID: 8420279]
  • T Takeuchi, K Shiratori, S Watanabe, J H Chang, Y Moriyoshi, K Shimizu. Secretin as a potential mediator of antiulcer actions of mucosal protective agents. Journal of clinical gastroenterology. 1991; 13 Suppl 1(?):S83-7. doi: 10.1097/00004836-199112001-00014. [PMID: 1940202]
  • K Shiratori, S Watanabe, T Takeuchi, K Shimizu. Plaunotol inhibits postprandial gastrin release by its unique secretin-releasing action in humans. Digestive diseases and sciences. 1990 Sep; 35(9):1140-5. doi: 10.1007/bf01537587. [PMID: 2390929]
  • K Shiratori, S Watanabe, T Takeuchi, J H Chang, Y Moriyoshi. Effect of plaunotol on release of plasma secretin and pancreatic exocrine secretion in humans. Pancreas. 1989; 4(3):323-8. doi: 10.1097/00006676-198906000-00008. [PMID: 2471968]
  • J H Chang, S Watanabe, K Shiratori, Y Moriyoshi, T Takeuchi. Plaunotol stimulates endogenous secretin release and exocrine pancreatic secretion in rats. Digestion. 1989; 44(3):142-7. doi: 10.1159/000199903. [PMID: 2483390]
  • . . . . doi: . [PMID: 19782428]