Sulfamethopyrazine (BioDeep_00000858471)

Main id: BioDeep_00000009363

 


代谢物信息卡片


Sulfamethopyrazine

化学式: C11H12N4O3S (280.0630082)
中文名称: 磺胺林
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: COC1=NC=CN=C1NS(=O)(=O)C2=CC=C(C=C2)N
InChI: InChI=1S/C11H12N4O3S/c1-18-11-10(13-6-7-14-11)15-19(16,17)9-4-2-8(12)3-5-9/h2-7H,12H2,1H3,(H,13,15)

描述信息

J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01E - Sulfonamides and trimethoprim > J01ED - Long-acting sulfonamides
D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents
C254 - Anti-Infective Agent > C29739 - Sulfonamide Anti-Infective Agent
D000890 - Anti-Infective Agents > D013424 - Sulfanilamides
Same as: D01216

同义名列表

2 个代谢物同义名

Sulfamethopyrazine; SULFALENE



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Hongyan Zhang, Li Ma, Wenbo Peng, Bing Wang, Yongning Sun. Association between gut microbiota and onset of type 2 diabetes mellitus: a two-sample Mendelian randomization study. Frontiers in cellular and infection microbiology. 2024; 14(?):1327032. doi: 10.3389/fcimb.2024.1327032. [PMID: 38596649]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Lorenzo Drago, Marco Toscano, Valentina Rodighiero, Elena De Vecchi, Giovanni Mogna. Cultivable and pyrosequenced fecal microflora in centenarians and young subjects. Journal of clinical gastroenterology. 2012 Oct; 46 Suppl(?):S81-4. doi: 10.1097/mcg.0b013e3182693982. [PMID: 22955365]
  • Lidao Bao, Shimin Bai, Gereltu Borijihan. Hypolipidemic effects of a new piperine derivative GB-N from Piper longum in high-fat diet-fed rats. Pharmaceutical biology. 2012 Aug; 50(8):962-7. doi: 10.3109/13880209.2012.654395. [PMID: 22494195]
  • V Sama, M Nadipelli, P Yenumula, M R Bommineni, R Mullangi. Effect of piperine on antihyperglycemic activity and pharmacokinetic profile of nateglinide. Arzneimittel-Forschung. 2012 Aug; 62(8):384-8. doi: 10.1055/s-0032-1314849. [PMID: 22753154]
  • Loredana Baffoni, Francesca Gaggìa, Diana Di Gioia, Cecilia Santini, Luca Mogna, Bruno Biavati. A Bifidobacterium-based synbiotic product to reduce the transmission of C. jejuni along the poultry food chain. International journal of food microbiology. 2012 Jul; 157(2):156-61. doi: 10.1016/j.ijfoodmicro.2012.04.024. [PMID: 22608658]
  • Sarka Rockova, Vojtech Rada, Jiri Nevoral, Petr Marsik, Eva Vlkova, Vera Bunesova. Inter-species differences in the growth of bifidobacteria cultured on human milk oligosaccharides. Folia microbiologica. 2012 Jul; 57(4):321-4. doi: 10.1007/s12223-012-0134-5. [PMID: 22491988]
  • Fabiana Carvalho Rodrigues, Adriano Simões Barbosa Castro, Vívian Carolina Rodrigues, Sérgio Antônio Fernandes, Edimar Aparecida Filomeno Fontes, Tânia Toledo de Oliveira, Hércia Stampini Duarte Martino, Célia Lúcia de Luces Fortes Ferreira. Yacon flour and Bifidobacterium longum modulate bone health in rats. Journal of medicinal food. 2012 Jul; 15(7):664-70. doi: 10.1089/jmf.2011.0296. [PMID: 22510044]
  • Xiao Fei Du, Jae-Jun Song, Seungug Hong, Jihye Kim. Ethanol extract of Piper longum L. attenuates gentamicin-induced hair cell loss in neonatal cochlea cultures. Die Pharmazie. 2012 Jun; 67(6):559-63. doi: ". [PMID: 22822547]
  • Xiaoli Sun, Kaibin Zhang, Xiuhong Ji, Yanwen Wang, Zidichouski Jeffrey, Yan Tong, Huimin Gao, Junzeng Zhang, Zhimin Wang. [Screening of pancreatic lipase and alpha-glucosidase inhibitors from Chinese dietary herbs]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2012 May; 37(9):1319-23. doi: 10.4268/cjcmm20120931. [PMID: 22803384]
  • Akihiro Ishizuka, Kotomi Tomizuka, Ryo Aoki, Tomohiko Nishijima, Yasuo Saito, Ryo Inoue, Kazunari Ushida, Takashi Mawatari, Takayuki Ikeda. Effects of administration of Bifidobacterium animalis subsp. lactis GCL2505 on defecation frequency and bifidobacterial microbiota composition in humans. Journal of bioscience and bioengineering. 2012 May; 113(5):587-91. doi: 10.1016/j.jbiosc.2011.12.016. [PMID: 22284965]
  • S Justin Packia Jacob, J S Finub, Anand Narayanan. Synthesis of silver nanoparticles using Piper longum leaf extracts and its cytotoxic activity against Hep-2 cell line. Colloids and surfaces. B, Biointerfaces. 2012 Mar; 91(?):212-4. doi: 10.1016/j.colsurfb.2011.11.001. [PMID: 22119564]
  • Deolinda M F Scalabrin, Susan H Mitmesser, Gjalt W Welling, Cheryl L Harris, John D Marunycz, D Carey Walker, Nico A Bos, Satu Tölkkö, Seppo Salminen, Jon A Vanderhoof. New prebiotic blend of polydextrose and galacto-oligosaccharides has a bifidogenic effect in young infants. Journal of pediatric gastroenterology and nutrition. 2012 Mar; 54(3):343-52. doi: 10.1097/mpg.0b013e318237ed95. [PMID: 21946836]
  • Nacim Zouari, Imen Ayadi, Nahed Fakhfakh, Ahmed Rebai, Sami Zouari. Variation of chemical composition of essential oils in wild populations of Thymus algeriensis Boiss. et Reut., a North African endemic species. Lipids in health and disease. 2012 Feb; 11(?):28. doi: 10.1186/1476-511x-11-28. [PMID: 22439877]
  • Malwina Michalak, Lise V Thomassen, Henna Roytio, Arthur C Ouwehand, Anne S Meyer, Jørn D Mikkelsen. Expression and characterization of an endo-1,4-β-galactanase from Emericella nidulans in Pichia pastoris for enzymatic design of potentially prebiotic oligosaccharides from potato galactans. Enzyme and microbial technology. 2012 Feb; 50(2):121-9. doi: 10.1016/j.enzmictec.2011.11.001. [PMID: 22226198]
  • Nuria Salazar, Patricia Ruas-Madiedo, Alicia Prieto, Luis P Calle, Clara G de Los Reyes-Gavilán. Characterization of exopolysaccharides produced by Bifidobacterium longum NB667 and its cholate-resistant derivative strain IPLA B667dCo. Journal of agricultural and food chemistry. 2012 Feb; 60(4):1028-35. doi: 10.1021/jf204034n. [PMID: 22229884]
  • Michele Malaguarnera, Marco Vacante, Tijana Antic, Maria Giordano, Giuseppe Chisari, Rosaria Acquaviva, Silvana Mastrojeni, Giulia Malaguarnera, Antonio Mistretta, Giovanni Li Volti, Fabio Galvano. Bifidobacterium longum with fructo-oligosaccharides in patients with non alcoholic steatohepatitis. Digestive diseases and sciences. 2012 Feb; 57(2):545-53. doi: 10.1007/s10620-011-1887-4. [PMID: 21901256]
  • N K Kovalenko, O A Poltavskaia, L B Zelenaia. [Bifidobacterial species composition of digestive tract of people of different age groups]. Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993). 2012 Jan; 74(1):8-13. doi: NULL. [PMID: 22545438]
  • Il-Hoon Jung, Jeong Hoon Lee, Yang-Jin Hyun, Dong-Hyun Kim. Metabolism of ginsenoside Rb1 by human intestinal microflora and cloning of its metabolizing β-D-glucosidase from Bifidobacterium longum H-1. Biological & pharmaceutical bulletin. 2012; 35(4):573-81. doi: 10.1248/bpb.35.573. [PMID: 22466563]
  • Ren-Ying Xu, Yan-Ping Wan, Qi-Yu Fang, Wei Lu, Wei Cai. Supplementation with probiotics modifies gut flora and attenuates liver fat accumulation in rat nonalcoholic fatty liver disease model. Journal of clinical biochemistry and nutrition. 2012 Jan; 50(1):72-7. doi: 10.3164/jcbn.11-38. [PMID: 22247604]
  • Manoj Kumar, Ravinder Nagpal, Rajesh Kumar, R Hemalatha, Vinod Verma, Ashok Kumar, Chaitali Chakraborty, Birbal Singh, Francesco Marotta, Shalini Jain, Hariom Yadav. Cholesterol-lowering probiotics as potential biotherapeutics for metabolic diseases. Experimental diabetes research. 2012; 2012(?):902917. doi: 10.1155/2012/902917. [PMID: 22611376]
  • Markku T Saarinen, Sampo J Lahtinen, Jens F Sørensen, Kirsti Tiihonen, Arthur C Ouwehand, Nina Rautonen, Andrew Morgan. Treatment of bran containing bread by baking enzymes; effect on the growth of probiotic bacteria on soluble dietary fiber extract in vitro. Bioscience, biotechnology, and biochemistry. 2012; 76(6):1135-9. doi: 10.1271/bbb.110977. [PMID: 22790935]
  • Hélène Moussu, Laurence Van Overtvelt, Stéphane Horiot, Sophie Tourdot, Sabi Airouche, Adrian Zuercher, Sébastien Holvoet, Guénolée Prioult, Sophie Nutten, Annick Mercenier, Laurent Mascarell, Philippe Moingeon. Bifidobacterium bifidum NCC 453 promotes tolerance induction in murine models of sublingual immunotherapy. International archives of allergy and immunology. 2012; 158(1):35-42. doi: 10.1159/000330101. [PMID: 22205338]
  • Zhijian Yu, Zhen Huang, Chongwen Sao, Yuanjian Huang, Fan Zhang, Jin Yang, Jie Lian, Zhongming Zeng, Wenshen Luo, Weiseng Zeng, Qiwen Deng. Bifidobacterium as an oral delivery carrier of interleukin-12 for the treatment of Coxsackie virus B3-induced myocarditis in the Balb/c mice. International immunopharmacology. 2012 Jan; 12(1):125-30. doi: 10.1016/j.intimp.2011.10.022. [PMID: 22088614]
  • Vasuki Ramesh, Rajeswary Hari, Samudram Pandian, Geetha Arumugam. Antioxidant activity of combined ethanolic extract of Eclipta alba and Piper longum Linn. Journal of complementary & integrative medicine. 2011 Dec; 8(?):. doi: 10.2202/1553-3840.1591. [PMID: 22718673]
  • P Bercik, A J Park, D Sinclair, A Khoshdel, J Lu, X Huang, Y Deng, P A Blennerhassett, M Fahnestock, D Moine, B Berger, J D Huizinga, W Kunze, P G McLean, G E Bergonzelli, S M Collins, E F Verdu. The anxiolytic effect of Bifidobacterium longum NCC3001 involves vagal pathways for gut-brain communication. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society. 2011 Dec; 23(12):1132-9. doi: 10.1111/j.1365-2982.2011.01796.x. [PMID: 21988661]
  • Junhui Liu, Ying Bi, Rong Luo, Xia Wu. Simultaneous UFLC-ESI-MS/MS determination of piperine and piperlonguminine in rat plasma after oral administration of alkaloids from Piper longum L.: application to pharmacokinetic studies in rats. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2011 Oct; 879(27):2885-90. doi: 10.1016/j.jchromb.2011.08.018. [PMID: 21903488]
  • Pieter Van den Abbeele, Philippe Gérard, Sylvie Rabot, Aurélia Bruneau, Sahar El Aidy, Muriel Derrien, Michiel Kleerebezem, Erwin G Zoetendal, Hauke Smidt, Willy Verstraete, Tom Van de Wiele, Sam Possemiers. Arabinoxylans and inulin differentially modulate the mucosal and luminal gut microbiota and mucin-degradation in humanized rats. Environmental microbiology. 2011 Oct; 13(10):2667-80. doi: 10.1111/j.1462-2920.2011.02533.x. [PMID: 21883787]
  • Dagmar Srůtková, Alena Spanova, Miroslav Spano, Vladimír Dráb, Martin Schwarzer, Hana Kozaková, Bohuslav Rittich. Efficiency of PCR-based methods in discriminating Bifidobacterium longum ssp. longum and Bifidobacterium longum ssp. infantis strains of human origin. Journal of microbiological methods. 2011 Oct; 87(1):10-6. doi: 10.1016/j.mimet.2011.06.014. [PMID: 21756944]
  • Songhee Jeon, Shambhunath Bose, Jinyoung Hur, Kiyoung Jun, Young-Kyoon Kim, Kyoung Sang Cho, Byung-Soo Koo. A modified formulation of Chinese traditional medicine improves memory impairment and reduces Aβ level in the Tg-APPswe/PS1dE9 mouse model of Alzheimer's disease. Journal of ethnopharmacology. 2011 Sep; 137(1):783-9. doi: 10.1016/j.jep.2011.06.046. [PMID: 21762767]
  • Jennifer Keiser, Hanan Sayed, Maged el-Ghanam, Hoda Sabry, Saad Anani, Aly el-Wakeel, Christoph Hatz, Jürg Utzinger, Sayed Seif el-Din, Walaa el-Maadawy, Sanaa Botros. Efficacy and safety of artemether in the treatment of chronic fascioliasis in Egypt: exploratory phase-2 trials. PLoS neglected tropical diseases. 2011 Sep; 5(9):e1285. doi: 10.1371/journal.pntd.0001285. [PMID: 21909440]
  • Nipat Simakachorn, Rodrigo Bibiloni, Phisek Yimyaem, Yothi Tongpenyai, Wandee Varavithaya, Dominik Grathwohl, Gloria Reuteler, Jean-Claude Maire, Stephanie Blum, Philippe Steenhout, Jalil Benyacoub, Eduardo J Schiffrin. Tolerance, safety, and effect on the faecal microbiota of an enteral formula supplemented with pre- and probiotics in critically ill children. Journal of pediatric gastroenterology and nutrition. 2011 Aug; 53(2):174-81. doi: 10.1097/mpg.0b013e318216f1ec. [PMID: 21788759]
  • Daniela C U Cavallini, Juliana Y Suzuki, Dulcinéia S P Abdalla, Regina C Vendramini, Nadiége D Pauly-Silveira, Mariana N Roselino, Roseli A Pinto, Elizeu A Rossi. Influence of a probiotic soy product on fecal microbiota and its association with cardiovascular risk factors in an animal model. Lipids in health and disease. 2011 Jul; 10(?):126. doi: 10.1186/1476-511x-10-126. [PMID: 21801422]
  • Hyang Mi An, Shin Young Park, Do Kyung Lee, Jung Rae Kim, Min Kyeong Cha, Si Won Lee, Hyung Taeck Lim, Kyung Jae Kim, Nam Joo Ha. Antiobesity and lipid-lowering effects of Bifidobacterium spp. in high fat diet-induced obese rats. Lipids in health and disease. 2011 Jul; 10(?):116. doi: 10.1186/1476-511x-10-116. [PMID: 21745411]
  • Giovanni V Coppa, Orazio Gabrielli, Lucia Zampini, Tiziana Galeazzi, Anna Ficcadenti, Lucia Padella, Lucia Santoro, Sara Soldi, Antonio Carlucci, Enrico Bertino, Lorenzo Morelli. Oligosaccharides in 4 different milk groups, Bifidobacteria, and Ruminococcus obeum. Journal of pediatric gastroenterology and nutrition. 2011 Jul; 53(1):80-7. doi: 10.1097/mpg.0b013e3182073103. [PMID: 21478759]
  • Suresh Kumar, Jitpal Kamboj, Suman, Sunil Sharma. Overview for various aspects of the health benefits of Piper longum linn. fruit. Journal of acupuncture and meridian studies. 2011 Jun; 4(2):134-40. doi: 10.1016/s2005-2901(11)60020-4. [PMID: 21704957]
  • Rolf Boesten, Frank Schuren, Kaouther Ben Amor, Monique Haarman, Jan Knol, Willem M de Vos. Bifidobacterium population analysis in the infant gut by direct mapping of genomic hybridization patterns: potential for monitoring temporal development and effects of dietary regimens. Microbial biotechnology. 2011 May; 4(3):417-27. doi: 10.1111/j.1751-7915.2010.00216.x. [PMID: 21375714]
  • Shreya S Shah, Gaurang B Shah, Satbeer D Singh, Priyanshi V Gohil, Kajal Chauhan, Khyati A Shah, Mehul Chorawala. Effect of piperine in the regulation of obesity-induced dyslipidemia in high-fat diet rats. Indian journal of pharmacology. 2011 May; 43(3):296-9. doi: 10.4103/0253-7613.81516. [PMID: 21713094]
  • H Rajeswary, R Vasuki, P Samudram, A Geetha. Hepatoprotective action of ethanolic extracts of Melia azedarach Linn. and Piper longum Linn and their combination on CCl4 induced hepatotoxicity in rats. Indian journal of experimental biology. 2011 Apr; 49(4):276-81. doi: ". [PMID: 21614891]
  • Nayan R Bhalodia, V J Shukla. Antibacterial and antifungal activities from leaf extracts of Cassia fistula l.: An ethnomedicinal plant. Journal of advanced pharmaceutical technology & research. 2011 Apr; 2(2):104-9. doi: 10.4103/2231-4040.82956. [PMID: 22171301]
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